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| Product | Description | |
|---|---|---|
| Cytochrome C | 500mg Pack Size. Group: Biochemicals, Organics, Research Organics & Inorganics. Formula: C42H54FeN8O6S2. CAS No. 9007-43-6. Prepack ID : 46874650-500mg. Molecular Weight : 886.91. |  |
| 6-Hydroxy Chlorzoxazone-[13C6] | 6-Hydroxychlorzoxazone-[13C6] is the labelled analogue of 6-Hydroxychlorzoxazone, which is a major metabolite of chlorzoxazone. Formed by the actions of cytochrome P450IIE1. Group: Pharmaceutical. Alternative Names: [13C6]-6-Hydroxychlorzoxazone; 5-Chloro-6-Hydroxy-3H-1,3-Benzoxazol-2-One-13C6; 5-Chloro-6-hydroxy-2(3H)-benzoxazolone-13C6; 6-Hydroxy Chlorzoxazone-13C6. CAS No. 475295-90-0. Pack Sizes: 10 mg. Product ID: BLP-000970. Molecular formula: C[13C]6H4ClNO3. Mole weight: 191.52. Custom synthesis is available. Send your inquiries for more information. |  London |
| Abiraterone Related Compound 7 | An impurity of Abiraterone , a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor. Group: Pharmaceutical. Alternative Names: Abiraterone Impurity 7. Pack Sizes: 1mg;1g;10g. Molecular formula: C47H61NO4. Mole weight: 704.01. Custom synthesis is available. Send your inquiries for more information. | London |
| Amentoflavone | Amentoflavone, a natural flavonoid isolated from the the seed of Ginkgo biloba L, exhibits anti-inflammatory activity, and inhibits NF-κB/DNA binding activity potently along with inhibition of degradation of IκBα and NF-κB translocation into nucleus in TNFα-activated A549 cells. Amentoflavone has the inhibition of LPS-induced NO formation, due to its inhibition of NF-kappaB by blocking degradation, which may be the mechanistic basis of the anti-inflammatory effects of amentoflavone. Uses: Cytochrome p-450 cyp2c9 inhibitors. Group: Pharmaceutical. Alternative Names: 4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 3''',8-Biflavone, 4',4''',5,5'',7,7''-hexahydroxy-; 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Ginkgetin, didemethyl-; Amenthoflavone; I3',II8-Biapigenin; NSC 295677; Tridemethylsciadopitysin. CAS No. 1617-53-4. Pack Sizes: 100 mg. Product ID: B2703-464494. Molecular formula: C30H18O10. Mole weight: 538.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Azamulin | Azamulin is an azole derivative of pleuromutilin. Azamulin is a highly selective inhibitor of cytochrome P450 3A4 (CYP3A4). Group: Pharmaceutical. Alternative Names: Azamulinum. CAS No. 76530-44-4. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04090. Molecular formula: C24H36N4O4S. Mole weight: 476.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Azoxystrobin | Azoxystrobin is a systemic fungicide commonly used in agriculture. It is used as an active agent protecting plants and fruit/vegetables from fungal diseases. It inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Group: Pharmaceutical. Alternative Names: Amistar; Bankit; Heritage; Quadris; methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate. CAS No. 131860-33-8. Pack Sizes: 5 g. Product ID: B0084-467187. Molecular formula: C22H17N3O5. Mole weight: 403.394. Custom synthesis is available. Send your inquiries for more information. | London |
| Bergamottin | Bergamottin (5-geranoxypsoralen) is a natural furanocoumarin found in the pulp of pomelos and grapefruits. It is also found in the peel and pulp of the bergamot orange, from which it was first isolated and from which its name is derived. It shows antiproliferative activity against HepG2 liver, HL-60 leukemia, and BGC-823 gastric cancer cell lines in a dose-dependent manner and induces cell death of CHO cells following near ultraviolet irradiation. Bergamottin inhibits the cytochrome P450 isoform 3A4 with Ki of 7.7 μM and is a mixed inhibitor of simvastatin drug metabolism with Ki of 174 μM. It also increases glucose consumption in HepG2 cells in a dose-dependent manner. Group: Pharmaceutical. Alternative Names: 5-Geranoxypsoralen; Bergamottin. CAS No. 7380-40-7. Pack Sizes: 10 mg. Product ID: B2703-097781. Molecular formula: C21H22O4. Mole weight: 338.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Byakangelicin | Byakangelicin is an effective inhibitor of sex hormones and affects the catabolism of endogenous hormones. It directly affects the cytochrome P450 isoform (CY) P3A4 in human hepatocytes. It is an inhibitor of aldose reductase used in the treatment of diabetic cataracts. Byakangelicin is a natural coumarin compound found in Murraya koenigii, Triphasia trifoliata, and other organisms. Group: Pharmaceutical. Alternative Names: 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxy-; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-, (R)-; 9-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one; Biacangelicin; (+)-Byakangelicin; 5-Methoxy-8-(2,3-dihydroxy-3-methylbutoxy)psoralene; Bjacangelicin; Bjakangelicin; Byankagelicine. CAS No. 482-25-7. Pack Sizes: 10 mg. Product ID: NP1139. Molecular formula: C17H18O7. Mole weight: 334.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Chalepensin | Chalepensin is a furanocoumarin found in several medicinal Rutaceae plants. Chalepensin acts as a cytochrome P450 (P450, CYP) inhibitor that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepensin also exhibits an antimicrobial effect against Streptococcus mutans. Group: Pharmaceutical. Alternative Names: Xylotenin; 3-(alpha,alpha-Dimethylallyl)psoralen; 6-(2-methylbut-3-en-2-yl)-7h-furo[3,2-g]chromen-7-one. CAS No. 13164-03-9. Pack Sizes: 5 mg. Product ID: NP1084. Molecular formula: C16H14O3. Mole weight: 254.285. Custom synthesis is available. Send your inquiries for more information. | London |
| Chamaechromone | Chamaechromone is isolated from the roots of Stellera chamaeja sme. Chamaechromone can undergo extensive phase I and phase II metabolism in rat. Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by α-naphthoflavone, and predominantly catalyzed by recombinant human cytochrome P450 1A2. Group: Pharmaceutical. Alternative Names: 3-[1,1-bis(4-hydroxyphenyl)-3-oxo-3-(2,4,6-trihydroxyphenyl)propan-2-yl]-5,7-dihydroxychromen-4-one. CAS No. 93413-00-4. Pack Sizes: 5 mg. Product ID: NP2301. Molecular formula: C30H22O10. Mole weight: 542.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Ciprofloxacin hydrochloride | Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline, a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. It is used for urogenital infections caused by sensitive bacteria. Uses: Cytochrome p-450 cyp1a2 inhibitors. Group: Pharmaceutical. Alternative Names: Ciprofloxacin hydrochloride. CAS No. 93107-08-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3410. Molecular formula: C17H19ClFN3O3. Mole weight: 367.8. Custom synthesis is available. Send your inquiries for more information. | London |
| Cobicistat | Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate. Uses: Anti-hiv agents. Group: Pharmaceutical. Alternative Names: Cobicistat, GS-9350; GS 9350; GS9350. CAS No. 1004316-88-4. Pack Sizes: 25 mg. Product ID: B0084-456314. Molecular formula: C40H53N7O5S2. Mole weight: 776.028. Custom synthesis is available. Send your inquiries for more information. | London |
| Cycloguanil hydrochloride | Cycloguanil is an active metabolite of proguanil, produced by the cytochrome P450 2C19 isoform. It is also an inhibitor of dihydrofolate reductase (DHFR) (Kis = 0.3 and 1.5 nM for Plasmodium and human forms, respectively). Uses: Antimalarials. Group: Pharmaceutical. Alternative Names: Chloroguanide Triazine; NSC 3074; 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine monohydrochloride. CAS No. 152-53-4. Pack Sizes: 500 mg. Product ID: B2693-118548. Molecular formula: C11H14ClN5·HCl. Mole weight: 288.2. Custom synthesis is available. Send your inquiries for more information. | London |
| Diosmetin | Diosmetin is a flavonoid that inhibits cytochrome P450 (CYP) isoforms 1A1 and 1B1 in human liver microsomes (Ki values of 89 and 16 nM, respectively). It exhibits anti-mutagenic and anti-allergic properties. Diosmetin has anti-oxidation, anti-infection, anti-shock and other functional foods, cosmetics and future drugs. Uses: Anti-inflammatory, antioxidant. Group: Pharmaceutical. Alternative Names: Diosmin EP Impurity F; Luteolin 4'-methyl ether; 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one; 4'-Methylluteolin; Salinigricoflavonol; Diosmetin; HSDB 8101; HSDB 8101; HSDB-8101; Luteolin 4'-methyl ether. CAS No. 520-34-3. Pack Sizes: 5 g. Product ID: NP2523. Molecular formula: C16H12O6. Mole weight: 300.266. Custom synthesis is available. Send your inquiries for more information. | London |
| Elacridar | Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Group: Pharmaceutical. Alternative Names: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. CAS No. 143664-11-3. Pack Sizes: 100 mg. Product ID: B0084-311800. Molecular formula: C34H33N3O5. Mole weight: 563.654. Custom synthesis is available. Send your inquiries for more information. | London |
| ELQ-300 | ELQ-300 is a potent and orally bioavailable antimalarial agent, and it is a novel inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (complex III in the electron transport chain). Group: Pharmaceutical. Alternative Names: ELQ300; ELQ 300; 6-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one. CAS No. 1354745-52-0. Pack Sizes: 50 mg. Product ID: B1370-334059. Molecular formula: C24H17ClF3NO4. Mole weight: 475.84. Custom synthesis is available. Send your inquiries for more information. | London |
| Famotidine | Famotidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. Unlike cimetidine, the first H2 antagonist, famotidine has no effect on the cytochrome P450 enzyme system, and does not appear to interact with other drugs. Group: Pharmaceutical. Alternative Names: Famotidine, Famotidine Hydrochloride, MK-208, Pepcid, YM-11170, YM11170, YM 11170, MK 208, MK208. CAS No. 76824-35-6. Pack Sizes: 10 g. Product ID: B2693-098225. Molecular formula: C8H15N7O2S3. Mole weight: 337.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Isoimperatorin | Isoimperatorin is a COX-2 inhibitor, and also inhibits cytochrome P450 (CYP) isoform 1A activity. In bone marrow-derived mast cells, isoimperatorin exhibits an inhibitory effect on degranulation. Isoimperatorin suppresses proliferation in melanoma cells. Uses: Antimycobacterial, antimycobacterial. Group: Pharmaceutical. Alternative Names: Iso Imperatorin; 4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one. CAS No. 482-45-1. Pack Sizes: 1 g. Product ID: NP1132. Molecular formula: C16H14O4. Mole weight: 270.284. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Homoserine | An impurity of Cobicistat, a cytochrome P450 3A (CYP3A) inhibitor used for the treatment of HIV/AIDS infection. Group: Pharmaceutical. Alternative Names: L-HomoSer-OH; L-2-Amino-4-hydroxybutyric acid; (S)-2-Amino-4-hydroxybutyric acid; Butyric acid, 2-amino-4-hydroxy-, L-; (S)-2-Amino-4-hydroxybutanoic acid; (S)-Homoserine; Butanoic acid, 2-amino-4-hydroxy-, (S)-; Homoserine; NSC 206251. CAS No. 672-15-1. Pack Sizes: 1mg;1g;10g. Product ID: BAT-005589. Molecular formula: C4H9NO3. Mole weight: 119.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Naringin | Naringin inhibits hepatic P-glycoprotein (P-gp) and some drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions. Naringin can be used as an edible additive, mainly for gum, refreshing drinks, etc. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation and antibacterial effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. Uses: Antioxidant, anticancer, anti-atherogenic. Group: Pharmaceutical. Alternative Names: Aurantiin; AI3-19008; AI319008; AI3 19008; Naringoside; (2S)-Naringin; Naringenin 7-Rhamnoglucoside; Naringenin 7-O-neohesperidoside; 4',5,7-trihydroxyflavanone 7-rhamnoglucoside; Naringenin-7-beta-neohesperidoside; (2S)-7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; K-ALL; KTB 30983; Naringenin 7-β-neohesperidoside; NSC 5548; OYL-BLP; Sanfix Naringin. CAS No. 10236-47-2. Pack Sizes: 250 g. Product ID: NP1904. Molecular formula: C27H32O14. Mole weight: 580.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Nitroso-sertraline-[d3] (cis racemic mixture) | Nitroso-sertraline-[d3] (cis racemic mixture) is a labelled analogue of nitroso-sertraline. Nitroso-sertraline is undergoing extensive first-pass metabolism by cytochrome P450 and selectively inhibits the reuptake of serotonin at the presynaptic neuronal membrane that is used to treat the major depressive disorder, a social anxiety disorder. Group: Pharmaceutical. Alternative Names: N-((1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(methyl-d3)nitrous amide; Nitroso-sertraline-d3 (cis racemic mixture). Pack Sizes: 10 mg. Product ID: BLP-014819. Molecular formula: C17H13D3Cl2N2O. Mole weight: 338.25. Custom synthesis is available. Send your inquiries for more information. | London |
| Paroxetine hydrochloride | Paroxetineis a selective serotonin reuptake inhibitor (SSRI). It is used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms. Uses: Cytochrome p-450 cyp2d6 inhibitors. Group: Pharmaceutical. Alternative Names: Win 47203; Win-47203; Win47203. CAS No. 78246-49-8. Pack Sizes: 25 g. Product ID: NP2639. Molecular formula: C19H21ClFNO3. Mole weight: 365.83. Custom synthesis is available. Send your inquiries for more information. | London |
| Pioglitazone hydrochloride | Pioglitazone hydrochloride, a thiazolidinedione antidiabetic drug, is a cytochrome P450 (CYP)2C8 and CYP3A4 enzymes inhibitor with Kis of 1.7, 11.8 and 32.1 μM for CYP2C8, CYP3A4 and CYP2C9, respectively. It is an agonist of the peroxisome proliferator-activated receptor γ. Uses: Hypoglycemic agents. Group: Pharmaceutical. Alternative Names: 5-[[4-[2-(5-Ethyl-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione Hydrochloride; AD-4833; Actos; U-72107A; 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride; NSC 758876; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, monohydrochloride. CAS No. 112529-15-4. Pack Sizes: 250 mg. Product ID: BBF-05868. Molecular formula: C19H20N2O3S.HCl. Mole weight: 392.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Plitidepsin | Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. Group: Pharmaceutical. Alternative Names: aplidin; aplidine; plitidepsin; dehydrodidemnin B. CAS No. 137219-37-5. Pack Sizes: 1 mg. Product ID: BAT-010093. Molecular formula: C57H87N7O15. Mole weight: 1110.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Rhodamine 110 chloride | Rhodamine 110 is a green fluorescent cationic dye that can be used in ezyme assays when incorporated with a hydrolytic substrate. Rhodamine 110 has also been used in a fluorescence quenching method for determining trace nitrite and as a probe for cytochrome P450 activity. Group: Pharmaceutical. Alternative Names: Rhodamine 110; Rhodamine 560; Rhodamine N; 3,6-diamino-9-(2-carboxyphenyl)-xanthylium, monochloride; 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid hydrochloride. CAS No. 13558-31-1. Pack Sizes: 1 g. Product ID: B1370-351461. Molecular formula: C20H15ClN2O3. Mole weight: 366.8. Custom synthesis is available. Send your inquiries for more information. | London |
| Rhodionin | Rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs. Rhodionin showed inhibitory activity with IC50 values of 0.761 μM and 0.420 μM, respectively. Rhodionin was determined to be non-competitive inhibitors with Ki values of 0.769 μM and 0.535 μM. Group: Pharmaceutical. Alternative Names: Herbacetin 7-O-a-rhamnopyranoside; 7-[(6-Deoxy-α-L-mannopyranosyl)oxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Herbacetin 7-O-α-L-rhamnopyranoside. CAS No. 85571-15-9. Pack Sizes: 5 mg. Product ID: NP1985. Molecular formula: C21H20O11. Mole weight: 448.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Secalciferol | Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification. lt mediates calcium and phosphorus homeostasis and inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. lt also can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Uses: Bone density conservation agents. Group: Pharmaceutical. Alternative Names: (24R)-24,25-Dihydroxyvitamin D3; Osteo D; (24R)-Hydroxycalcidiol. CAS No. 55721-11-4. Pack Sizes: 1 mg. Product ID: B0084-375020. Molecular formula: C27H44O3. Mole weight: 416.64. Custom synthesis is available. Send your inquiries for more information. | London |
| Seneciphylline | Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase. Group: Pharmaceutical. Alternative Names: Jacodine; (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione; 13,19-didehydro-12-hydroxysenecionan-11,16-dione. CAS No. 480-81-9. Pack Sizes: 10 mg. Product ID: NP0002. Molecular formula: C18H23NO5. Mole weight: 333.4. Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-(+)-Mephenytoin | (S)-(+)-Mephenytoin is an S-isomer of Mephenytoin, which is known to target sodium channel protein type 5 subunit alpha. Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. It can be used to screen for such mutations by assaying its metabolites in urine. Group: Pharmaceutical. Alternative Names: (S)-5-Ethyl-3-methyl-5-phenylhydantoin; (+)-Mephenytoin; (5S)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione. CAS No. 70989-04-7. Pack Sizes: 50 mg. Product ID: B1370-204709. Molecular formula: C12H14N2O2. Mole weight: 218.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Terconazole | Terconazole is an antifungal drug used to treat vaginal yeast infection. It has a relatively broad spectrum compared to azole compounds. It may exert its antifungal activity by disrupting normal fungal cell membrane permeability. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It is a suitable compound for prophylaxis for those that suffer from chronic vulvovaginal candidiasis. It has a far greater selectively for yeast cytochrome P-450 than for mammalian microsomal cytochrome P-450. It may also be used in vitro to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of Candida albicans. It was developed by Johnson & Johnson and has been listed. Uses: Terconazole is an antifungal drug used to treat vaginal yeast infection. it may also be used in vitro to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of candida albicans. Group: Pharmaceutical. Alternative Names: Piperazine, 1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, cis-; cis-1-(p-{[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine; Piperazine, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, rel-; r. CAS No. 67915-31-5. Pack Sizes: 500 mg. Product ID: B0084-400393. Molec | London |
| Tetrahydropiperine | Tetrahydropiperine is a piperine alkaloid originally isolated from P. longum. It acts as an agonist of transient receptor potential vanilloid type 1 (TRPV1). It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH) and 7-methoxycoumarin O-demethylase (MOCD) activity in rat liver microsomes. Group: Pharmaceutical. Alternative Names: THP; Tetrahydropiperin; 5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpentan-1-one. CAS No. 23434-88-0. Pack Sizes: 100 mg. Product ID: B2703-059108. Molecular formula: C17H23NO3. Mole weight: 289.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Uniconazole | Uniconazole is a plant growth hormone that inhibits cytochrome P450 707As, resulting in a suppression of gibberellin production. Uses: Fungicides, industrial. Group: Pharmaceutical. Alternative Names: 1H-1,2,4-Triazole-1-ethanol, β-[(4-chlorophenyl)methylene]-α-(1,1-dimethylethyl)-, (βE)-; (βE)-β-[(4-Chlorophenyl)methylene]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol; 1H-1,2,4-Triazole-1-ethanol, β-[(4-chlorophenyl)methylene]-α-(1,1-dimethylethyl)-, (E)-(±)-; (E)-1-(4-Chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol; 1H-1,2,4-Triazole-1-ethanol, β-[(4-chlorophenyl)methylene]-α-(1,1-dimethylethyl)-, (E)-; M 13144; Majic; Majic S 3307D; Pentefenzol; Prunit; S 07; S 327D; S 3307; S 3307D; Sumagic; Sumiseven; XE 1019; XE 1019D. CAS No. 83657-22-1. Pack Sizes: 25 g. Product ID: B0084-078170. Molecular formula: C15H18ClN3O. Mole weight: 291.77. Custom synthesis is available. Send your inquiries for more information. | London |
| Vitamin D3 | Cholecalciferol is a naturally occurring form of vitamin D which is obtained from dietary sources, such as fish, or through the conversion of 7-dehydrocholesterol by ultraviolet light. It is subsequently metabolized to 25-hydroxyvitamin D3 and the active form 1,25-dihydroxyvitamin D3 by cytochrome P450 isoforms in the liver. It could prevent proliferation of cancer cells. Vitamin supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; Cholecalciferol; Duphafral D3 1000; Delsterol; Deparal; Ebivit; Oleovitamin D3; Provitina; Ricketon; Vi-De3; Videkhol; Vigorsan; Vitinc Dan-Dee-3; Colecalciferol. CAS No. 67-97-0. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05875. Molecular formula: C27H44O. Mole weight: 384.64. Custom synthesis is available. Send your inquiries for more information. | London |
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