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| Product | Description | |
|---|---|---|
| Cyclopamine | Cyclopamine (11-deoxojervine) is a naturally occurring chemical that belongs to the group of steroidal jerveratrum alkaloids. It is a teratogen isolated from the corn lily (Veratrum californicum) that causes usually fatal birth defects. It can prevent the fetal brain from dividing into two lobes (holoprosencephaly) and cause the development of a single eye (cyclopia). It does so by inhibiting the hedgehog signaling pathway (Hh). Cyclopamine is useful in studying the role of Hh in normal development, and as a potential treatment for certain cancers in which Hh is overexpressed. Group: Pharmaceutical. CAS No. 4449-51-8. Pack Sizes: 100 mg. Product ID: BBF-03880. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Cyclopamine Impurities | Cyclopamine Impurities serve a fundamental role in biomedical exploration, crucial for deciphering cancer-associated signaling pathways. These impurities facilitate the development of therapeutic agents targeting the Hedgehog signaling cascade, primarily implicated in basal cell carcinoma and medulloblastoma treatment, significantly advancing oncological therapy research. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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