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| Product | Description | |
|---|---|---|
| 3-(4-Methylphenyl)-5-(trifluoromethyl)-1H-pyrazole | An impurity of Celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. CAS No. 219986-64-8. Pack Sizes: 10 mg. Product ID: B2694-309476. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 4-Desmethyl-2-methyl Celecoxib | 4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. CAS No. 170569-99-0. Pack Sizes: 100 mg. Product ID: B2694-468625. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Methyl-3,4-diphenyl-4,5-dihydroisoxazol-5-ol | An intermediate for the preparation of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Uses: Intermediate for the preparation of valdecoxib. Group: Pharmaceutical. CAS No. 181696-73-1. Pack Sizes: 200 mg. Product ID: B2694-053919. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetophenone-[13C] | Acetophenone-[Methyl-13C] is an intermediate in synthesizing Ibuprofen-[13C6], a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Group: Pharmaceutical. CAS No. 71777-36-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-009173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetophenone-[13C6] | Acetophenone-[13C6] is an intermediate in synthesizing Ibuprofen-[13C]6, a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Pharmaceutical. CAS No. 125770-94-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-000007. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetophenone-[α-13C] | Acetophenone-[α-13C] is an intermediate in synthesizing Ibuprofen-[13C6], a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Group: Pharmaceutical. CAS No. 10383-88-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-010986. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetophenone-[α,β-13C2] | Acetophenone-[α,β-13C2] is an intermediate in synthesizing Ibuprofen-[13C6], a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Group: Pharmaceutical. CAS No. 190314-15-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-010985. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetophenone-[d8] | Acetophenone-[d8] is an intermediate in synthesizing Ibuprofen-[13C6], a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Group: Pharmaceutical. CAS No. 19547-00-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-010984. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetophenone-[methyl-d3] | Acetophenone-[methyl-d3] is an intermediate in synthesizing Ibuprofen-[13C6], a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Group: Pharmaceutical. CAS No. 17537-31-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-010987. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib | Celecoxib is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID) used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. Uses: Cyclooxygenase 2 inhibitors. Group: Pharmaceutical. CAS No. 169590-42-5. Pack Sizes: 5 g. Product ID: B0084-451901. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib EP Impurity A | A meta positional isomer of Celecoxib with selective inhibitory activity against human cyclooxygenase-2. Group: Pharmaceutical. CAS No. 170570-01-1. Pack Sizes: 100 mg. Product ID: B2694-468619. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib EP Impurity B | An isomeric impurity of Celecoxib with selective inhibitory activity against human cyclooxygenase-2. Group: Pharmaceutical. CAS No. 331943-04-5. Pack Sizes: 100 mg. Product ID: B2694-468620. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib Impurity 2 | An impurity of celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. CAS No. 948293-46-7. Pack Sizes: 10 mg. Product ID: B2694-468624. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Clematomandshurica saponin B | Clematomandshurica saponin B is a triterpenoid saponin isolated from the roots and rhizomes of Clematis mandshurica with inhibitory effect against cyclooxygenase-2. Group: Pharmaceutical. CAS No. 916649-91-7. Pack Sizes: 5 mg. Product ID: B0005-053726. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diclofenac Potassium | Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. It is a competitive inhibitor of cyclooxygenase (COX) that suppresses the production of prostaglandins. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Uses: Nsaid. Group: Pharmaceutical. CAS No. 15307-81-0. Pack Sizes: 20 g. Product ID: B0084-059596. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (-)-Epiafzelechin | (-)-Epiafzelechin exhibits various modes of action in suppressing HSV-2 multiplication. Uses: Antioxidant; cyclooxygenase-1 inhibitor; anti-inflammatory. Group: Pharmaceutical. CAS No. 24808-04-6. Pack Sizes: 5 mg. Product ID: NP2037. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Epicatechin | (-)-Epicatechin is a 2R,3R stereoisomer of catechin and is a naturally occurring flavanol. It is a powerful antioxidant and could inhibit cyclooxygenase. L-Epicatechin is a natural compound found in the woods of Acacia catechu (L.F.) Willd, it can be used in cosmetics material. Uses: Anti-oxidant; anti-atherogenic. Group: Pharmaceutical. CAS No. 490-46-0. Pack Sizes: 5 g. Product ID: NP1874. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Etodolac Impurity L | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B2694-471282. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GYY-4137 Morpholine salt | GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Group: Pharmaceutical. CAS No. 106740-09-4. Pack Sizes: 100 mg. Product ID: B2693-272139. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Harpagoside | Harpagoside, isolated from the Harpagophytum procumbens (Devil's Claw) root or Crophularia ningpoensis Hemsl (Figwort), inhibited lipopolysaccharide-induced mRNA levels. Harpagoside also inhibited protein expression of cyclooxygenase-2 and inducible nitric oxide in HepG2 cells, which involves suppression of NF-kappaB activation, thereby inhibiting downstream inflammation and subsequent pain events. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 19210-12-9. Pack Sizes: 50 mg. Product ID: NP3892. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen piconol | Ibuprofen piconol is an anti-inflammatory agent that can be synthesized from Ibuprofen. It acts as a cyclooxygenase inhibitor. Group: Pharmaceutical. CAS No. 64622-45-3. Pack Sizes: 5 g. Product ID: B0046-448719. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Irigenin | Irigenin is a natural compound isolated from the rhizomes of Belamcanda chinensis (L.) DC. Irigenin prevents metastatic capacity of lung cancer cells by selectively blocking Extra Domain A. Irigenin has anti-inflammatory effects that can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable cytotoxic effect. Group: Pharmaceutical. CAS No. 548-76-5. Pack Sizes: 20 mg. Product ID: NP2498. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mofezolac | Mofezolac is a cyclooxygenase-1 selective inhibitor. Uses: Cyclooxygenase inhibitors. Group: Pharmaceutical. CAS No. 78967-07-4. Pack Sizes: 10 g. Product ID: B2693-008944. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mussaenoside | Mussaenoside is a natural iridoid found in the herbs of Melampyrum roseum Maxim, it can inhibit the release of pro-inflammatory cytokines induced by LPS, the production of nitric oxide (NO) and prostaglandin E2, and the expression of inducible NO synthase and cyclooxygenase-2 induced by lipopolysaccharide (LPS) in the RAW264.7 murine macrophage cell line. Mussaenoside also exhibits the activity of anti-inflammatory. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 64421-27-8. Pack Sizes: 1 mg. Product ID: NP3859. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetamide | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Group: Pharmaceutical. CAS No. 198471-06-6. Pack Sizes: 20 mg. Product ID: B2694-484462. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Osthol | Osthole is a coumarin which is isolated from Cnidium monnieri (L.) Cusson. Osthole is a calcium channel modulator via inhibiting phosphodiesterases. It also regulates the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. Osthole is a natural compound used in cosmetics material. Uses: Anti-tumor; anti-cancer; may be used as bio-pesticides. Group: Pharmaceutical. CAS No. 484-12-8. Pack Sizes: 100 g. Product ID: NP1032. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rebamipide | Rebamipide has been shown to enhance mucosal defense by scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2. Uses: Enzyme inhibitors. Group: Pharmaceutical. CAS No. 90098-04-7. Pack Sizes: 20 g. Product ID: B0084-100251. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Resveratrol | Resveratrol is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity), mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity), and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose-and time-dependent manner. Resveratrol is a natural compound used in cosmetic materials. It is widely used in anti-aging and wrinkle removal, whitening and whitening spots, antibacterial and anti-inflammatory, oil control and acne, anti-allergy and analgesia, scar repair, hair care and other products, and it is compatible with lotion cream formula, gel formula and water formula. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 501-36-0. Pack Sizes: 20 g. Product ID: BBF-03781. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SKF-86002 | SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Group: Pharmaceutical. CAS No. 72873-74-6. Pack Sizes: 300 mg. Product ID: B0084-195907. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Valdecoxib Impurity E | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Group: Pharmaceutical. CAS No. 1373038-63-1. Pack Sizes: 5 mg. Product ID: B2694-484468. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Valdecoxib Impurity I | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Group: Pharmaceutical. CAS No. 1373038-59-5. Pack Sizes: 5 mg. Product ID: B2694-484471. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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