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| Product | Description | |
|---|---|---|
| CROSS CUT CAPS | CROSS CUT CAPS, UK suppliers of laboratory chemicals wanted |  |
| 1,3-Bis(2-hydroxyethyl)-5,5-dimethylhydantoin | 1,3-Bis(2-hydroxyethyl)-5,5-dimethylhydantoin, a vital crosslinker renowned for its indispensable role in the realm of biomedical science. Leveraged in cutting-edge medical treatments for cancer and infectious diseases, its multifaceted properties exhibit unparalleled efficacy and innovation in therapeutic interventions. Group: Pharmaceutical. CAS No. 26850-24-8. Pack Sizes: 2 g. Product ID: B1370-088990. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Ibudilast | Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Group: Pharmaceutical. CAS No. 50847-11-5. Pack Sizes: 5 g. Product ID: B0084-329045. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TBA-354 | TBA-354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamanid and greater than that of PA-824. TBA-354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates. TBA-354 is 5 to 10 times more potent than PA-824, but selected mutants are cross-resistant to PA-824 and delamanid. TBA-354 is 2 to 4 times more potent than PA-824 when combined with bedaquiline, and when administered at a dose equivalent to that of PA-824, TBA-354 demonstrated superior sterilizing efficacy. TBA-354 has high bioavailability and a long elimination half-life. In vitro studies suggest a low risk of drug-drug interactions. Low-dose aerosol infection models of acute and chronic murine tuberculosis reveal time- and dose-dependent in vivo bactericidal activity that is at least as potent as that of delamanid and more potent than that of PA-824. Group: Pharmaceutical. CAS No. 1257426-19-9. Pack Sizes: 100 mg. Product ID: B2693-463155. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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