Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| 2,4,6-trichloro-N-phenylaniline | A Diclofenac impurity which is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Group: Pharmaceutical. CAS No. 15362-44-4. Pack Sizes: 10 mg. Product ID: B1370-379610. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 4-[3-(Acryloyloxy)propoxy]benzoic acid | 4-[3-(Acryloyloxy)propoxy]benzoic acid, an essential raw material in the synthesis of pharmaceuticals and agrochemicals, possesses enormous potential as a COX-2 inhibitor, thereby providing considerable therapeutic benefits in alleviating inflammation and pain. Moreover, it serves as an indispensable reagent in organic chemistry and is exclusively utilized in the synthesis of polymeric compounds and surface functionalization. Its multifaceted applications in various fields highlight its enormous industrial significance. Group: Pharmaceutical. CAS No. 245349-46-6. Pack Sizes: 100 mg. Product ID: B0001-103450. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Methoxybenzenemethanamine-[d3] | 4-Methoxybenzenemethanamine-[d3] is an isotopic labelled analogue of 4-Methoxybenzylamine, an intermediate used in the synthesis of COX2 inhibitors based on a pyrimidine scaffold. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BLP-014118. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Vinylsyringol | 4-Vinylsyringol, a phenolic compound with antioxidant properties, shows potential as a COX-2 inhibitor and is a flavoring agent extracted from crude canola oil. It may inhibit tumor cell growth while inducing cell apoptosis. Group: Pharmaceutical. CAS No. 28343-22-8. Pack Sizes: 100 mg. Product ID: B0001-453486. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acemetacin-[13C6] | Acemetacin-[13C6] is the labelled analogue of Acemetacin. Acemetacin is a COX inhibitor; A non-steroidal anti-inflammatory drug. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-000972. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetaminophen | Acetaminophen is a selective COX-2 inhibitor. It has antipyretic, analgesic, and anti-inflammatory effects. Group: Pharmaceutical. CAS No. 103-90-2. Pack Sizes: 1mg; 1g; 10g. Product ID: NP3382. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetaminophen-[d3] | Acetaminophen-[d3] is the labelled analogue of Acetaminophen, which is a selective COX-2 inhibitor. Acetaminophen is a medication for the treatment of fever and pains. Group: Pharmaceutical. CAS No. 60902-28-5. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-011551. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetylsalicylic Acid-[d4] | Acetylsalicylic Acid-[d4] is the labelled analogue of Acetylsalicylic Acid, which is an antithrombotic, anti-inflammatory, antipyretic analgesic. Acetylsalicylic Acid is an inhibitor of Cox-1 and Cox-2. Group: Pharmaceutical. CAS No. 97781-16-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-012816. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| a-Chlorobenzyl 4-Fluorophenyl Ketone | a-Chlorobenzyl 4-Fluorophenyl Ketone is derived from Benzyl 4-Fluorophenyl Ketone (B279785), which is used in preparation and evaluation of 2,3-diarylpyrazines and quinoxalines as selective COX-2 inhibitors. Group: Pharmaceutical. CAS No. 62148-67-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BB069533. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AG 126 | Tyrphostins are protein tyrosine kinase inhibitors developed to inhibit cell growth through blocking the activity of certain GFRK (growth factor receptor kinases). AG 126 selectively inhibits the phosphorylation of ERK1 and ERK2 at 25-50 μM. It also inhibits the production of TNF-α (tumor necrosis factor-α), attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in animal models. AG 126 is a poor inhibitor of epidermal GFRK with IC50 of 450 μM and platelet-derived GFRK with IC50 > 100 μM. AG 126 may represent a new approach for the therapy of inflammation. Uses: Anti- inflammation. Group: Pharmaceutical. CAS No. 118409-62-4. Pack Sizes: 100 mg. Product ID: B1370-195904. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| α-Mangostin | It was isolated from Garcinia mangostana Linn (Guttiferae). It is an anti-inflammatory agent. It can inhibit the activity of COX-2, an inhibitor of mutant IDH1 (IDH1-R132H). Group: Pharmaceutical. CAS No. 6147-11-1. Pack Sizes: 1 g. Product ID: BBF-04170. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Berberine hydrochloride | Berberine hydrochloride is an isoqinoline alkaloid and acts as a COX-2 inhibitor that exhibits chemopreventive activity against colon tumor formation. Study in humans and hamsters shows that berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides. It also inhibits c-Jun and suppresses inflammation and cancers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 633-65-8. Pack Sizes: 250 g. Product ID: B0084-073975. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Carprofen | Carprofen is a COX-2 inhibitor used as a non-steroidal anti-inflammatory drug. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 53716-49-7. Pack Sizes: 25 g. Product ID: B0046-464118. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib | Celecoxib is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID) used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. Uses: Cyclooxygenase 2 inhibitors. Group: Pharmaceutical. CAS No. 169590-42-5. Pack Sizes: 5 g. Product ID: B0084-451901. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Desmethyl Etoricoxib | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Group: Pharmaceutical. CAS No. 202409-31-2. Pack Sizes: 100 mg. Product ID: B2694-471299. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diclofenac EP Impurity C | Diclofenac EP Impurity C is an impurity of Diclofenac, which is a non-selective COX inhibitor used as a non-steroidal anti-inflammatory drug (NSAID). Group: Pharmaceutical. CAS No. 27204-57-5. Pack Sizes: 100 mg. Product ID: B2694-470082. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diclofenac Potassium | Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. It is a competitive inhibitor of cyclooxygenase (COX) that suppresses the production of prostaglandins. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Uses: Nsaid. Group: Pharmaceutical. CAS No. 15307-81-0. Pack Sizes: 20 g. Product ID: B0084-059596. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Esculentic acid | Esculentic acid has been isolated from the roots of Phytolacca acinosa Roxb. It has protective effects against LPS-induced endotoxic shock. Esculentic acid is a selective COX-2 inhibitor and has anti-inflammatory effect. Uses: Anti-inflammatory effect. Group: Pharmaceutical. CAS No. 103974-74-9. Pack Sizes: 5 mg. Product ID: NP6746. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Etoricoxib | Etoricoxib is a selective COX-2 inhibitor. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 202409-33-4. Pack Sizes: 1 g. Product ID: B0084-461973. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Etoricoxib Impurity 10 | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Group: Pharmaceutical. CAS No. 316149-01-6. Pack Sizes: 1 mg. Product ID: B0042-471301. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Etoricoxib Impurity 7 | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Group: Pharmaceutical. CAS No. 646459-39-4. Pack Sizes: 50 mg. Product ID: B2694-471305. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Etoricoxib N-Oxide | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Group: Pharmaceutical. CAS No. 325855-74-1. Pack Sizes: 100 mg. Product ID: B2694-471302. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fenazox | Amfenac is a COX inhibitor with IC50 of 0.25 and 0.15 μM for COX-1 and COX-2, respectively. Group: Pharmaceutical. CAS No. 61618-27-7. Pack Sizes: 5 g. Product ID: NP3190. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Firocoxib | Firocoxib is a selective COX-2 inhibitor that can be used to control postoperative pain and inflammation associated with soft tissue and orthopedic surgery in dogs. Group: Pharmaceutical. CAS No. 189954-96-9. Pack Sizes: 5 g. Product ID: B2693-086516. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen | Ibuprofen is an inhibitor of COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. Ibuprofen has been used to treat mild-moderate pain, fever, and inflammation. Group: Pharmaceutical. CAS No. 15687-27-1. Pack Sizes: 500 g. Product ID: B2693-084941. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen lysine | Ibuprofen lysine is a non-selective COX inhibitor that can be used as an anti-inflammatory drug. Group: Pharmaceutical. CAS No. 57469-77-9. Pack Sizes: 2 g. Product ID: B2693-072008. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Iguratimod | Iguratimod is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. Uses: Anti-inflammation agent. Group: Pharmaceutical. CAS No. 123663-49-0. Pack Sizes: 250 mg. Product ID: B0084-056331. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isoimperatorin | Isoimperatorin is a COX-2 inhibitor, and also inhibits cytochrome P450 (CYP) isoform 1A activity. In bone marrow-derived mast cells, isoimperatorin exhibits an inhibitory effect on degranulation. Isoimperatorin suppresses proliferation in melanoma cells. Uses: Antimycobacterial, antimycobacterial. Group: Pharmaceutical. CAS No. 482-45-1. Pack Sizes: 1 g. Product ID: NP1132. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| L-α-Methyltyrosine | L-α-Methyltyrosine is a tyrosine hydroxylase inhibitor. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. It reduces the elevated levels of catecholamines associated with pheochromocytoma, thus preventing hypertension. It significantly inhibits COX-2 activity and has anti-inflammatory and anti-ulcer effects. Uses: L-α-methyltyrosine is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. Group: Pharmaceutical. CAS No. 672-87-7. Pack Sizes: 5 g. Product ID: BAT-008124. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lornoxicam | Lornoxicam is a non-steroidal COX-1/COX-2 inhibitor used as an anti-inflammatory drug. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 70374-39-9. Pack Sizes: 1 g. Product ID: B2693-185746. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lumiracoxib Impurities | Lumiracoxib Impurities, integral in pharmacological examinations, act as essential analytical markers, facilitating meticulous calibration and stringent evaluation of drug integrity and therapeutic efficacy in osteoarthritis and rheumatoid maladies. By aiding in degradation entity identification, they ensure the safety and effectiveness of lumiracoxib, a selective COX-2 inhibitor, in clinical applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mavacoxib | Mavacoxib, a pyrazol derivative, has been found to be a COX-2 Inhibitor that could be used in pain and inflammation therapy for dogs. Group: Pharmaceutical. CAS No. 170569-88-7. Pack Sizes: 1 g. Product ID: B2693-244941. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Naproxen | (S)-Naproxen is a non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 μM and 2.0-28.4 μM, respectively. It is an anti-inflammatory agent with analgesic and antipyretic activities, which is commonly used for the treatment of rheumatoid arthritis and gout. Uses: The treatment of rheumatoid arthritis and gout. Group: Pharmaceutical. CAS No. 22204-53-1. Pack Sizes: 50 g. Product ID: NP2658. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nepafenac | Nepafenac is an inhibitor of COX-1 and COX-2. Group: Pharmaceutical. CAS No. 78281-72-8. Pack Sizes: 250 mg. Product ID: B0046-464115. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nimesulide Impurity E | An impurity of Nimesulide, which is a selective COX-7 inhibitor. Group: Pharmaceutical. CAS No. 905858-63-1. Pack Sizes: 10 mg. Product ID: B0159-478173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nimesulide Impurity F | An impurity of Nimesulide, which is a selective COX-5 inhibitor. Group: Pharmaceutical. CAS No. 51765-72-1. Pack Sizes: 100 mg. Product ID: B0159-478172. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Trans-Feruloyltyramine | N-trans-Feruloyltyramine(NTF) ,a natural plant phenylpropanoid which is isolated from the herbs of Cannabis sativa L. exhibits the activity of anti-oxidative and has hepatoprotective effect. N-trans-Feruloyltyramine is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor. Uses: Anti-oxidative. Group: Pharmaceutical. CAS No. 66648-43-9. Pack Sizes: 10 mg. Product ID: NP0183. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Parecoxib Impurity 1 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Group: Pharmaceutical. CAS No. 1708094-99-8. Pack Sizes: 5 mg. Product ID: B2694-338806. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Parecoxib Impurity 24 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Group: Pharmaceutical. CAS No. 198470-82-5. Pack Sizes: 5 mg. Product ID: B2694-338807. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Polmacoxib | Polmacoxib is a first-in-class NSAID drug candidate that acts as a dual inhibitor of COX-2 and carbonic anhydrase (CA). It exhibits superior safety for cardiovascular, renal, and gastrointestinal tissues due to its dual COX-2 and CA binding properties. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. Group: Pharmaceutical. CAS No. 301692-76-2. Pack Sizes: 10 mg. Product ID: B0084-462767. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| R-Ibuprofen | R-Ibuprofen is an inhibitor of Cox-1 and Cox-2 used as a nonsteroidal anti-inflammatory drug. Group: Pharmaceutical. CAS No. 51146-57-7. Pack Sizes: 500 mg. Product ID: B2693-120682. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rofecoxib Impurities | Rofecoxib Impurities are critical in the biomedical industry for evaluating drug safety and efficacy. These impurities help researchers understand degradation pathways and adverse effect mechanisms linked to Rofecoxib, a COX-2 inhibitor used for pain and inflammation in osteoarthritis and other conditions. Their study aids in enhancing drug formulation and regulatory compliance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Salicin | Salicin is a phenol β-glycosid produced from willow bark that shows an anti-inflammatory effect. It acts as a non-selective COX inhibitor (IC50 values > 100 μM for COX-1 and COX-2). Salicin is a natural compound used in cosmetics material. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 138-52-3. Pack Sizes: 250 g. Product ID: NP5372. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SKF-86002 | SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Group: Pharmaceutical. CAS No. 72873-74-6. Pack Sizes: 300 mg. Product ID: B0084-195907. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sphondin | Sphondin is isolated from the fruits of Heracleum sibiricum L. It possesses an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells. Uses: Anti-inflammatory activity. Group: Pharmaceutical. CAS No. 483-66-9. Pack Sizes: 25 mg. Product ID: NP1078. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Xanthohumol | Xanthohumol is a prenylated flavonoid isolated from Hops (Humulus lupulus L.), displaying anticancer and anti-angiogenic properties. It acts as an inhibitor of DGAT, COX-1 and COX-2. Group: Pharmaceutical. CAS No. 6754-58-1. Pack Sizes: 250 mg. Product ID: B2703-464713. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
