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| Product | Description | |
|---|---|---|
| COMBINATION pH ELECTRODE | COMBINATION pH ELECTRODE, UK suppliers of laboratory chemicals and apparatus needed |  |
| 16-Dehydropregnenolone acetate | 16-Dehydropregnenolone acetate is an impurity of Abiraterone, which is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: Dehydropregnenolone acetate; 16,17-Didehydropregnenolone acetate. CAS No. 979-02-2. Pack Sizes: 25 g. Product ID: NP6241. Molecular formula: C23H32O3. Mole weight: 356.51. Custom synthesis is available. Send your inquiries for more information. |  London |
| 2,5-Dioxopyrrolidine Sacubitril | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. Alternative Names: (2R,4S)-5-Biphenyl-4-yl-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester. CAS No. 1038924-97-8. Pack Sizes: 100 mg. Product ID: B1604-479386. Molecular formula: C24H27NO4. Mole weight: 393.483. Custom synthesis is available. Send your inquiries for more information. | London |
| 2R,4R-Sacubitril | An isomer of Sacubitril. Sacubitril is a neprilysin inhibitor that is commonly used in combination with valsartan (an angiotensin II receptor blocker) to form a dual-acting medication known as sacubitril/valsartan. Group: Pharmaceutical. Alternative Names: (2R,4R)-Sacubitril; LCZ 696 Impurity B; 4-((rel-(2R,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; Sacubitril-(2R,4R) Isomer. CAS No. 766480-48-2. Pack Sizes: 5 mg. Product ID: B1370-459004. Molecular formula: C24H29NO5. Mole weight: 411.49. Custom synthesis is available. Send your inquiries for more information. | London |
| (2R,4S)-4-Amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride | An impurity of Sacubitril, a neprilysin inhibitor that is used in combination with valsartan to treat high blood pressure. Group: Pharmaceutical. Alternative Names: 1038924-71-8; (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride(2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid;hydrochloride; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride; SCHEMBL597864. CAS No. 1038924-71-8. Pack Sizes: 100 mg. Product ID: B2694-013668. Molecular formula: C18H22ClNO2. Mole weight: 319.8. Custom synthesis is available. Send your inquiries for more information. | London |
| (2R,4S)-5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. Alternative Names: 1012341-50-2; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid(2R,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid; FJ7AWX8DMFUNII-FJ7AWX8DMF. CAS No. 1012341-50-2. Pack Sizes: 100 mg. Product ID: B1604-479394. Molecular formula: C23H29NO4. Mole weight: 383.488. Custom synthesis is available. Send your inquiries for more information. | London |
| (2S)-Isopropyl 2-(((perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Group: Pharmaceutical. Alternative Names: Propan-2-yl (2S)-2-{[pentafluorophenoxy(phenoxy)phosphoryl]amino}propanoate; N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl]-L-Alanine 1-Methylethyl Ester; N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine1-methylethyl ester. CAS No. 1256490-52-4. Pack Sizes: 25 mg. Product ID: B1628-480349. Molecular formula: C18H17F5NO5P. Mole weight: 453.302. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A is an inhibitor of S-adenosylmethionine-dependent methyltransferase. In combination with sodium butyrate, 3-Deazaneplanocin A can induce epigenetically reprogramming of human embryonic stem cells (hESC). Group: Pharmaceutical. Alternative Names: DZNep; (1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol. CAS No. 102052-95-9. Pack Sizes: 10 mg. Product ID: B0084-462897. Molecular formula: C12H14N4O3. Mole weight: 262.26. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Deoxy-3-acetyl abiraterone-3-ene | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 1-((8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl)ethanone. Pack Sizes: 10 mg. Product ID: B0038-007224. Molecular formula: C26H31NO. Mole weight: 373.54. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Deoxy 3-chloroabiraterone | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-((8R,9S,10R,13S,14S)-3-Chloro-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Pack Sizes: 10 mg. Product ID: B0038-007226. Molecular formula: C24H30ClN. Mole weight: 367.95. Custom synthesis is available. Send your inquiries for more information. | London |
| (3R,5S)-5-Biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. Alternative Names: 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-. CAS No. 1038924-70-7. Pack Sizes: 100 mg. Product ID: B1604-479385. Molecular formula: C18H19NO. Mole weight: 265.356. Custom synthesis is available. Send your inquiries for more information. | London |
| 4,4'-Diaminodiphenylsulfone | Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase. Uses: Anti-inflammatory agent. Group: Pharmaceutical. Alternative Names: 4-(4-aminophenyl)sulfonylaniline. CAS No. 80-08-0. Pack Sizes: 1 kg. Product ID: NP2822. Molecular formula: C12H12N2O2S. Mole weight: 248.3. Custom synthesis is available. Send your inquiries for more information. | London |
| 5,10,15,20-tetrakis(4-aminophenyl)porphyrinatozinc(II) | 5,10,15,20-tetrakis(4-aminophenyl)porphyrinatozinc(II), a porphyrin-derived molecule, has garnered significant scientific interest due to its potential in anticancer therapies. The compounds photochemical properties may be aptly harnessed for photodynamic therapy, effectively shrinking tumors. Moreover, the compounds antioxidant attributes have garnered considerable attention, creating a possibility for treatment of oxidative stress-inflicted ailments. Recent studies have induced optimism for the compounds use in co-treatments, in combination with frontline therapy drugs to better combat cancer. Group: Pharmaceutical. CAS No. 67595-98-6. Pack Sizes: 10 mg. Product ID: B2708-285096. Molecular formula: C44H32N8Zn. Mole weight: 738.182. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate | An impurity of Prasugrel. Prasugrel is a platelet inhibitor and an irreversible antagonist of P2Y12ADP receptors that prevents the formation of blood clots. It was appoved for the treatment of acute coronary syndrome (ACS), and some cardiovascular diseasess in combination with Aspirin. Group: Pharmaceutical. Alternative Names: 5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate maleate; Prasugrel Impurity 4. CAS No. 1373350-61-8. Pack Sizes: 20 mg. Product ID: B0219-007244. Molecular formula: C24H25ClFNO7S. Mole weight: 525.972. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone isopropyl ether | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-[3-(1-Methylethoxy)androsta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. CAS No. 2484719-15-3. Pack Sizes: 1mg;1g;10g. Product ID: 2484719-15-3. Molecular formula: C27H37NO. Mole weight: 391.59. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone Methyl Ether | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-[(3β)-3-Methoxyandrosta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. CAS No. 1470276-23-3. Pack Sizes: 1mg;1g;10g. Product ID: 1470276-23-3. Molecular formula: C25H33NO. Mole weight: 363.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone O-β-D-glucuronide | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: Abiraterone O-beta-D-glucuronide; (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol β-D-Glucuronide. CAS No. 2307194-33-6. Pack Sizes: 1mg;1g;10g. Product ID: 2307194-33-6. Molecular formula: C30H39NO7. Mole weight: 525.63. Custom synthesis is available. Send your inquiries for more information. | London |
| AC 186 | AC 186, also called GTPL8897, a diphenyl substituted cyclohexane derivatives, decreases Aβ levels in combination with ACP-105 in a rat model of Alzheimer's disease. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Group: Pharmaceutical. Alternative Names: 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]phenol; GTPL8897; SCHEMBL14672438; AC-186; AC 186; AC186; AKOS025147323; 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]phenol; AC 186|4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol. CAS No. 1421854-16-1. Pack Sizes: 1mg;1g;10g. Product ID: 1421854-16-1. Molecular formula: C18H17F3O. Mole weight: 306.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Afoxolaner | Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies. It is administered orally in meat-flavoured tablets, and poisons fleas once they start feeding. It is used either alone or as a combination treatment with milbemycin oxime. Group: Pharmaceutical. Alternative Names: 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide. CAS No. 1093861-60-9. Pack Sizes: 100 mg. Product ID: B2692-475054. Molecular formula: C26H17ClF9N3O3. Mole weight: 625.87. Custom synthesis is available. Send your inquiries for more information. | London |
| Anhydro abiraterone | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-Androsta-3,5,16-trien-17-yl-pyridine; 3-((8R,9S,10R,13S,14S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine; 17-(3-Pyridyl)androsta-3,5,16-triene. CAS No. 154229-20-6. Pack Sizes: 10 mg. Product ID: B0038-007225. Molecular formula: C24H29N. Mole weight: 331.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Artemisinin | Artemisinin is a natural product originally isolated from plants of the genus Artemisia. It effectively kills malarial parasites of the genus Plasmodium. It is usually used in combination therapy for the treatment of malaria. Artemisinin is also used against a wide range of trematodes, including Schistosoma. Artemisinin is an inhibitor of human NOS2 (iNOS) with anticancer activity. Group: Pharmaceutical. Alternative Names: (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epox12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; Artemisine; Arteannuin; Huanghuahaosu; QHS; Qinghaosu; (+)-Artemisinin. CAS No. 63968-64-9. Pack Sizes: 100 g. Product ID: BBF-04621. Molecular formula: C15H22O5. Mole weight: 282.33. Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam Sodium Salt | Avibactam Sodium Salt, a novel non-?-lactam ?-lactamase inhibitor, binds covalently to Ambler class A ?-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. Group: Pharmaceutical. Alternative Names: sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[321]octan-6-yl sulfate; NXL104; NXL-104; NXL 104; Avibactam; Avibactam sodium. CAS No. 1192491-61-4. Pack Sizes: 500 mg. Product ID: B0084-465274. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD0364 | AZD-0364 is a potent and selective ERK2 inhibitor, which has an IC50 value of 0.6 nM. AZD-0364 is measured in the A375 phospho-p90RSK assays with IC50s of 5.7 nM. AZD-0364 can inhibit the growth of a panel of cancer cell lines. The combination of Selumetinib and AZD-0364 ethanesulfonic acid results in a reduction in tumor growth. Group: Pharmaceutical. Alternative Names: AZD-0364; AZD 0364; tizaterkib. CAS No. 2097416-76-5. Pack Sizes: 25 mg. Product ID: B2693-291616. Molecular formula: C24H24F2N8O2. Mole weight: 494.5. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD3965 | AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Group: Pharmaceutical. Alternative Names: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AZD3965; AZD-3965; AZD 3965. CAS No. 1448671-31-5. Pack Sizes: 25 mg. Product ID: B2693-463251. Molecular formula: C21H24F3N5O5S. Mole weight: 515.51. Custom synthesis is available. Send | London |
| AZD-5363 | AZD-5363 is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AZD-5363 binds to and inhibits all AKT isoforms. This agent may be used as monotherapy or combination therapy for a variety of human cancers. Group: Pharmaceutical. Alternative Names: AZD5363; AZD 5363; Capivasertib. CAS No. 1143532-39-1. Pack Sizes: 10 mg. Product ID: B2693-457058. Molecular formula: C21H25ClN6O2. Mole weight: 428.9152. Custom synthesis is available. Send your inquiries for more information. | London |
| BDT-1006 | BDT-1006 is a dendritic acrylate with an average functionality of 6. The hyper-branched structure of BDT-1006 imparts the unique combination of low diluted viscosity with unmatched chemical and thermal resistance, which is ideal in applications where withstanding exposure to the harshest conditions is paramount. Great for high-temperature applications because thermogravimetric analysis indicates the oligomer doesnt decompose until 377 °C. Uses: Graphic arts, coatings, electronics, digital inks. Group: Oligomer. Oligomer Functionality: 6. Viscosity [CP]: 1,500 (Neat). Durometer Hardness: 90D. Tensile Strength [MPa]: 17. Elongation at Break [%]: 3. Elegonation with %: 3%. Categories: Oligomers. |  |
| BDT-1015 | A dendritic acrylate with an average functionality of 15. The hyper-branched structure of BDT-1015 imparts a unique combination of low diluted viscosity with unmatched chemical and thermal resistance. This is ideal in applications where withstanding exposure to the hardest of conditions is paramount. BDT-1015 is also great for high-temperature applications because thermogravimetric analysis indicates the oligomer doesnt decompose until 372°C. Uses: Graphic arts, coatings, electronics, digital inks. Group: Oligomer. Oligomer Functionality: 15. Viscosity [CP]: 31,000 (Neat). Durometer Hardness: 89D. Tensile Strength [MPa]: 30. Elongation at Break [%]: 3. Elegonation with %: 3%. Categories: Oligomers. | |
| BDT-4330 | A dendritic acrylate with an average functionality of 30. The hyper-branched structure of BDT-4330 imparts the unique combination of low diluted viscosity with unmatched chemical and thermal resistance, which is ideal in applications where withstanding exposure to the harshest conditions is paramount. Great for high-temperature applications because thermogravimetric analysis indicates the oligomer doesnt decompose until 397°C. Uses: Graphic arts, coatings, electronics, digital inks. Group: Oligomer. Oligomer Functionality: 30. Viscosity [CP]: 1,500 (Neat). Durometer Hardness: 94D. Tensile Strength [MPa]: 39. Elongation at Break [%]: 1.7. Elegonation with %: 1.7%. Categories: Oligomers. | |
| Bictegravir | Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM for strand transfer activity. Bictegravir is a drug of the integrase inhibitor class that was copied from Dolutegravir by scientists at Gilead Sciences. Bictegravir also inhibits HIV-1 viral infection in MT-2 and MT-4 cells, CD4+ T cells, and macrophages (EC50s = 1.5, 2.5, 1.5, and 6.6 nM, respectively) without exhibiting cytotoxicity (CC50s = 10.3, 3.7, 13, and 29.8 μM, respectively). In 2016, bictegravir was in a Phase 3 trial as part of a single tablet regimen in combination with tenofovir alafenamide (TAF) and emtricitabine (FTC) for the treatment of HIV-1 infection. Group: Pharmaceutical. Alternative Names: GS-9883; GS 9883; GS9883. CAS No. 1611493-60-7. Pack Sizes: 100 mg. Product ID: B2693-058383. Molecular formula: C21H18F3N3O5. Mole weight: 449.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Butafosfan | Butafosfan, a component of Catosal, is licensed for the treatment of metabolic disorders or as a tonic in swine. It reduces the stress-induced cortisol (C696302, d4 labelled) response after mixing of unfamiliar pigs. It can also increase milk production in Holstein cows in combination with cyanocobalamin. Group: Pharmaceutical. Alternative Names: P-[1-(Butylamino)-1-methylethyl]-phosphinic Acid; [1-(Butylamino)-1-methylethyl]-phosphinic Acid; 1-(Butylamino)-1-methylethylphosphonous Acid; Butaphosphan. CAS No. 17316-67-5. Pack Sizes: 1mg;1g;10g. Product ID: 17316-67-5. Molecular formula: C7H18NO2P. Mole weight: 179.2. Custom synthesis is available. Send your inquiries for more information. | London |
| C12-200 | C12-200 is almost a macromolecule. It contains multiple tertiary amines, the pKa of which should also be close to but no greater than 7. Ionizable lipids in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. Group: Pharmaceutical. Alternative Names: 1,1'-((2-(4-(2-((2-(Bis(2-hydroxydodecyl)amino)ethyl)(2-hydroxydodecyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(dodecan-2-ol). CAS No. 1220890-25-4. Pack Sizes: 1 g. Product ID: B1370-358162. Molecular formula: C70H145N5O5. Mole weight: 1136.93. Custom synthesis is available. Send your inquiries for more information. | London |
| CHIR-99021 | CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. It enhances reprogramming of mouse embryonic fibroblasts, transduced by Oct4 and Klf4 only, into iPSCs in combination with tranylcypromine. It also induces cardiomyocyte differentiation from human embryonic stem (ES). Uses: Potential antineoplastic agent. Group: Pharmaceutical. Alternative Names: CHIR-99021; CT99021; 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile. CAS No. 252917-06-9. Pack Sizes: 100 mg. Product ID: B0084-462893. Molecular formula: C22H18Cl2N8. Mole weight: 465.342. Custom synthesis is available. Send your inquiries for more information. | London |
| Cyclosporin | It is produced by the strain of Polypocladiurn inflatum. It has a strong immunosuppressive action, but also has anti-inflammatory and weak antifungal effects. The mechanism of immunosuppression is the combination of cyclosporin A and cyclosporin-binding protein in T cells, which inhibits the activity of Calcineurin, and then impedes the transposition of intracellular transcription factors into the nucleus, and inhibits the interleukin-2 transcription, resulting in immunosuppression. It is mainly used for kidney transplantation, bone marrow and heart transplantation, and is one of the most important immunosuppressive agents in clinical application. Uses: Enzyme inhibitors. Group: Pharmaceutical. Alternative Names: Cyclosporins. CAS No. 79217-60-0. Pack Sizes: 1mg;1g;10g. Product ID: BBF-01751. Custom synthesis is available. Send your inquiries for more information. | London |
| dasabuvir | Dasabuvir is an antiviral drug for the treatment of hepatitis C. It inhibits hepatitis C virus (HCV) non-nucleoside NS5B palm polymerase to suppress RNA replicase. Dasabuvir is commonly used in combination with ombitasvir/paritaprevir/ritonavir to effect on HCV type 1. Uses: The treatment of hepatitis c. Group: Pharmaceutical. Alternative Names: ABT333; ABT-333; ABT 333, Dasabuvir. Trade names: Viekira Pak (with ombitasvir/paritaprevir/ritonavir tablets), Exviera; N-(6-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide. CAS No. 1132935-63-7. Pack Sizes: 100 mg. Product ID: B0084-462255. Molecular formula: C26H27N3O5S. Mole weight: 493.578. Custom synthesis is available. Send your inquiries for more information. | London |
| Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate 4-methylbenzenesulfonate | An impurity of Pemetrexed, which has been approved by FDA in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug. Group: Pharmaceutical. Alternative Names: (S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate 4-methylbenzenesulfonate; N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]L-glutamic acid; 4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl-L-glutamic acid diethyl ester p-toluenesulfonate salt. CAS No. 165049-28-5. Pack Sizes: 2.5 g. Product ID: NP3162. Molecular formula: C31H37N5O9S. Mole weight: 655.72. Custom synthesis is available. Send your inquiries for more information. | London |
| Dipivefrin hydrochloride | Dipivefrin is a prodrug of epinephrine that is hydrolyzed by cholinesterase and other esterases in the cornea to epinephrine. It reduces the density of cultured bovine primary trabecular meshwork cells. Additionally, it induces an elongated, fibroblast-like morphology and disrupts the actin cytoskeleton in bovine primary trabecular meshwork cells when used at a concentration of 103 μM. Formulations containing dipivefrin have been used alone and in combination with β-adrenergic receptor antagonists for the treatment of glaucoma. Group: Pharmaceutical. Alternative Names: Dipivefrin HCl; Dipivefrine hydrochloride; AKPro. CAS No. 64019-93-8. Pack Sizes: 1mg;1g;10g. Product ID: 64019-93-8. Molecular formula: C19H29NO5·HCl. Mole weight: 387.9. Custom synthesis is available. Send your inquiries for more information. | London |
| DOPE | DOPE, also known as 1,2-Dioleoyl-sn-glycero-3-PE or 1,2-DOPE, is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery. Group: Pharmaceutical. Alternative Names: 18:1 PE; 1,2-Dioleoyl-sn-glycero-3-PE; 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine; 1,2-DOPE; PE(18:1/18:1); Phophatidylethanolamine(18:1n9/18:1n9); Phophatidylethanolamine(18:1w9/18:1w9); 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; PE(18:1(9Z)/18:1(9Z)); 2-Aminoethyl (R)-2,3-Bis(oleoyloxy)propyl Hydrogen Phosphate; Olein, 1,2-di-, 2-aminoethyl hydrogen phosphate, L-; 9-Octadecenoic acid (9Z)-, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester. CAS No. 4004-5-1. Pack Sizes: 1 g. Product ID: B4059-163865. Molecular formula: C41H78NO8P. Mole weight: 744.05. Custom synthesis is available. Send your inquiries for more information. | London |
| Dulaglutide | Dulaglutide is a medication used for the treatment of type 2 diabetes in combination with diet and exercise. Group: Pharmaceutical. Alternative Names: LY2189265. CAS No. 923950-08-7. Pack Sizes: 5 mg. Product ID: BAT-009065. Custom synthesis is available. Send your inquiries for more information. | London |
| EAI045 | EAI045 is an allosteric, non-ATP competitive inhibitor of mutant EGFR. In vitro studies proved that EAI045 is active and selective for T790M- harboring EGFR mutants that are in a monomer state. In vivo the combination of EAI045 and cetuximab caused a marked tumor shrinkage in a mouse model carrying the EGFR mutant with L858R/T790M/C797S. Therefore, EAI045 is the first allosteric inhibitor that targets T790M and C797S EGFR mutants but it is effective only in combination with cetuximab. Group: Pharmaceutical. Alternative Names: 2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide; 2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide; EAI045; EAI 045; EAI-045. CAS No. 1942114-09-1. Pack Sizes: 50 mg. Product ID: B0084-475458. Molecular formula: C19H14FN3O3S. Mole weight: 383.397. Custom synthesis is available. Send your inquiries for more information. | London |
| Eflornithine hydrochloride, hydrate | Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. It is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. It displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways. It also demonstrates antiparasitic activity in a model of C. parvum infection. Group: Pharmaceutical. Alternative Names: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; MDL 71782 hydrochloride hydrate; RMI 71782 hydrochloride hydrate; MDL71782 hydrochloride hydrate; RMI71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate; Vaniqa hydrochloride hydrate. CAS No. 96020-91-6. Pack Sizes: 10 g. Product ID: BAT-008153. Molecular formula: C6H15ClF2N2O3. Mole weight: 236.64. Custom synthesis is available. Send your inquiries for more information. | London |
| Elexacaftor | Elexacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector used as a medication for cystic fibrosis treatment in combination with ivacaftor and tezacaftor. Group: Pharmaceutical. Alternative Names: VX-445; VX445; (S)-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide. CAS No. 2216712-66-0. Pack Sizes: 25 mg. Product ID: B1370-381497. Molecular formula: C26H34F3N7O4S. Mole weight: 597.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Entacapone | Entacapone is a selective and reversible inhibitor of the enzyme catechol-O-methyltransferase (COMT) (IC50 = 151 nM), commonly used in combination with other medications for the treatment of Parkinson's disease. Group: Pharmaceutical. Alternative Names: 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2E)-; Comtan; HSDB 8251; HSDB-8251; HSDB8251; OR-611; OR 611; OR611; (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (E)-; (E)-Entacapone; Comtess; Entacom; Parkicapone. CAS No. 130929-57-6. Pack Sizes: 500 mg. Product ID: B0084-057038. Molecular formula: C14H15N3O5. Mole weight: 305.29. Custom synthesis is available. Send your inquiries for more information. | London |
| Entinostat | Entinostat is a histone deacetylase (HDAC) inhibitor displaying antiproliferative and antineoplastic effects. Entinostat induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), which slows cell growth, differentiation, and tumor development in vivo. Entinostat is potentially used as an antitumor drug in combination with other drugs like adriamycin, PARP inhibitors and Hsp90 inhibitors. Uses: Histone deacetylase inhibitors. Group: Pharmaceutical. Alternative Names: MS275; MS-275; MS 2275; SNDX275; SNDX-275; SNDX 275; Entinostat; pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate. CAS No. 209783-80-2. Pack Sizes: 500 mg. Product ID: B0084-062759. Molecular formula: C21H20N4O3. Mole weight: 376.416. Custom synthesis is available. Send your inquiries for more information. | London |
| Gadopentetate dimeglumine | Gadopentetate dimeglumine, also known as SH-L-451A, is a complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), and is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI. Group: Pharmaceutical. Alternative Names: 2-[bis[2-[carboxylatomethyl(carboxymethyl)amino]ethyl]amino]acetate;gadolinium(3+);(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol; Diethylenetriaminepenta-acetic Acid, Gadolinium; Dimeglumine, Gadolinium DTPA; Dimeglumine, Gadopentetate; DTPA, Gadolinium; Gadolinium Diethylenetriaminepenta acetic Acid; Gadolinium Diethylenetriaminepenta-acetic Acid; Gadolinium DTPA; Gadolinium DTPA; Dimeglumine; Gadolinium DTPA Dimeglumine Salt; Gadolinium DTPA Disodium Salt; Gadopentetate Dimeglumine; Gadopentetic Acid; Gd DTPA; Gd-DTPA; Magnevist; Magnevist Enteral; Magnograf; Magnograf Enteral. CAS No. 86050-77-3. Pack Sizes: 1mg;1g;10g. Product ID: 86050-77-3. Molecular formula: C28H54GdN5O20. Mole weight: 938. Custom synthesis is available. Send your inquiries for more information. | London |
| Gelatin | Gelatin is used as a thickening agent and emulsifier in pharmaceutical formulations. It is a complex combination of proteins obtained by hydrolysis of collagen by boiling skin, tendons, ligaments, bones, etc. Group: Pharmaceutical. Alternative Names: Gelatins; Gelatins, acetylated, conjugates; Gelatins, conjugates; 225 Bloom; AGP 28 (gelatin); BCN-HL (gelatin); CLV (gelatin); CLW (gelatin); Collagens, gelatins; Coni-Snap; Conjugates acetylated gelatins; Conjugates, gelatins; CP (gelatin); DAB 7 (gelatin); E 200 (gelatin); Gelodan G; Gelofusine; KV 3000 (gelatin); Medigelatin; Oetker; Pharmagel A; Surgifoam; Vitrigel; VYSE; Z-KN 707. CAS No. 9000-70-8. Pack Sizes: 100 g. Product ID: B1370-194066. Custom synthesis is available. Send your inquiries for more information. | London |
| Hydroxychloroquine Sulfate | Hydroxychloroquine Sulfate is an autophagy inhibitor that induces autophagic cell death. It also inhibits TLR9. Hydroxychloroquine is an antimalarial drug, and in combination with other medications, it can be used in the treatment of some autto-immune diseases. It has been used in emergency of COVID-19. Group: Pharmaceutical. Alternative Names: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate. CAS No. 747-36-4. Pack Sizes: 100 g. Product ID: B2693-076365. Molecular formula: C18H28ClN3O5S. Mole weight: 433.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Idelalisib | Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Group: Pharmaceutical. Alternative Names: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. CAS No. 870281-82-6. Pack Sizes: 250 mg. Product ID: B0084-307712. Molecular formula: C22H18FN7O. Mole weight: 415.432. Custom synthesis is available. Send your inquiries for more information. | London |
| Isopropyl-β-D-thiogalactopyranoside | IPTG is a galactose analog that is used in combination with X-GAL in cloning procedures requiring expression of β-galactosidase activity. Group: Pharmaceutical. Alternative Names: IPTG; Isopropyl-beta-D-thiogalactopyranoside; Isopropyl β-D-thiogalactoside (IPTG); Isopropyl β-D-1-thiogalactopyranoside; Isopropyl 1-thio-b-D-galactopyranoside; Isopropyl 1-Thio-β-D-galactopyranoside; Isopropyl β-D-thiogalactoside; 1-Methylethyl 1-thio-beta-D-galactopyranoside. CAS No. 367-93-1. Pack Sizes: 100 g. Product ID: BAT-008017. Molecular formula: C9H18O5S. Mole weight: 238.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Lactoferrin (17-41) | Lactoferrin (17-41) is the 17-41 fragment of Lactoferrin that exhibits anti-fungal properties in combination of other anti-fungal agents. Uses: Lactoferrin is a multifunctional glycoprotein that plays a crucial role in various biological processes, including antimicrobial activity, immune modulation, and iron homeostasis. in recent years, research has shown that lactoferrin holds great potential in the field of drug discovery and development due to its diverse range of biological activities and therapeutic properties. saliva, tears, and. Group: Pharmaceutical. Alternative Names: Lactoferrin; Lactoferrin, from bovine milk; Lactoferricin B; Lfcin B; H-Phe-Lys-Cys(1)-Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly-Ala-Pro-Ser-Ile-Thr-Cys(1)-Val-Arg-Arg-Ala-Phe-OH. CAS No. 146897-68-9. Pack Sizes: 10 g. Product ID: BAT-010208. Molecular formula: C141H224N46O29S3. Mole weight: 3123.78. Custom synthesis is available. Send your inquiries for more information. | London |
| Laropiprant | a drug used in combination with niacin to reduce blood cholesterol (LDL and VLDL) that is no longer sold. Uses: A potent, selective dp1 receptor antagonist. Group: Pharmaceutical. Alternative Names: (3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-cyclopent[b]indole-3-acetic acid. CAS No. 571170-77-9. Pack Sizes: 50 mg. Product ID: B0084-474242. Molecular formula: C21H19ClFNO4S. Mole weight: 435.91. Custom synthesis is available. Send your inquiries for more information. | London |
| LEE011 succinate | LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models. Group: Pharmaceutical. Alternative Names: Ribociclib succinate; LEE 011 succinate; LEE-011 succinate. CAS No. 1374639-75-4. Pack Sizes: 1 g. Product ID: B2693-463203. Molecular formula: C27H36N8O5. Mole weight: 552.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Levamisole Impurity D (HCl salt form) | The hydrochloride of Levamisole Impurity D. Levamisole is a medication used for the treatment of parasitic worm infections. It was also indicated to be effective for colon cancer therapy in combination with fluorouracil. Group: Pharmaceutical. Alternative Names: 6-phenyl-2,3-dihydroimidazo[2,1-b]thiazole hydrochloride; AC1MD4BJ; CTK8I7338; MolPort-000-653-456. CAS No. 4335-29-9. Pack Sizes: 30 mg. Product ID: B1298-007230. Molecular formula: C11H11ClN2S. Mole weight: 238.733. Custom synthesis is available. Send your inquiries for more information. | London |
| Lopinavir | An antiretroviral medication acts as a protease inhibitor. It is a co-formulation with a sub-therapeutic dose of ritonavir, as a component of combination therapy to treat HIV/AIDS. Group: Pharmaceutical. Alternative Names: ABT 378; ABT-378; ABT378; Aluviran; Kaletra. CAS No. 192725-17-0. Pack Sizes: 1 g. Product ID: B0084-086623. Molecular formula: C37H48N4O5. Mole weight: 628.81. Custom synthesis is available. Send your inquiries for more information. | London |
| LY2109761 | LY2109761 is a novel inhibitor of TGF-β receptor type I/type II kinases (IC50 = 69 nM), displaying antitumor activity. In vivo study demonstrated that LY2109761, in combination with gemcitabine, significantly reduced the tumor burden, prolonged survival, and reduced spontaneous abdominal metastases. Group: Pharmaceutical. Alternative Names: LY-2109761; 4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine. CAS No. 700874-71-1. Pack Sizes: 100 mg. Product ID: B2693-286403. Molecular formula: C26H27N5O2. Mole weight: 441.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Manganese | A chemical element with the symbol Mn and atomic number 25. It is a hard, brittle, silvery metal, often found in minerals in combination with iron. Manganese is a transition metal with a multifaceted array of industrial alloy uses, particularly in stainless steels. Uses: Laboratory chemicals, Industrial & for professional use. CAS No. 7439-96-5. |  |
| Matrixyl 3000 | Matrixyl 3000 is an anti-aging ingredient developed by Sederma. Matrixyl 3000 is a combination of palmitoyl oligopeptide and palmitoyl tetrapeptide-7. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BAT-006226. Custom synthesis is available. Send your inquiries for more information. | London |
| Megestrol | Megestrol is an orally active progestogen. Megestrol is used in combinations as an oral contraceptive and antineoplastic agent. Uses: Antineoplastic agents, hormonal; progestational hormones, synthetic. Group: Pharmaceutical. Alternative Names: 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione. CAS No. 3562-63-8. Pack Sizes: 10 g. Product ID: B2692-066963. Molecular formula: C22H30O3. Mole weight: 342.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Mericol | Are a range of casein binders of various different properties and uses, offering a combination of modern, technically advanced, whilst retaining traditional formulatory values. The range is produced with only the highest quality of casein to instil quality and consistency to the product and offer the finishers a complete range to suit all their requirements. Uses: Leather Finishing Chemicals. Pack Sizes: 30, 60, 120, 1000. |  NE England |
| Micafungin | Micafungin, also known as FK463, is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. In a mouse model of septic A. fumigatus infection, although non-treated mice survived for a maximum of only 6 days, the survival rate of micafungin-treated mice (0.1 mg kg-1) increased to 20%, while the survival rate of mice treated with a combination of micafungin (0.1 mg kg-1) and KB425796-C (32 mg kg-1) increased to 100% during the 31-day post-infection period. Uses: Antifungal agents. Group: Pharmaceutical. Alternative Names: 1-[(4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; Mycamine; FK463. CAS No. 235114-32-6. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03857. Molecular formula: C56H71N9O23S. Mole weight: 1270.27. Custom synthesis is available. Send your inquiries for more information. | London |
| Minocycline hydrochloride | Minocycline (INN) is a semi-synthetic broad-spectrum tetracycline antibiotic. Minocycline hydrochloride is the most lipid-soluble form, which binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. In combination with CHIR 99021, (S)-(+)-Dimethindene maleate and human leukemia inhibitory factor, it induces the formation of extended pluripotent stem (EPS) cells. Group: Pharmaceutical. Alternative Names: Minocycline HCl; Arestin; Minomycin. CAS No. 13614-98-7. Pack Sizes: 5 g. Product ID: BBF-03822. Molecular formula: C23H27N3O7.HCl. Mole weight: 493.94. Custom synthesis is available. Send your inquiries for more information. | London |
| MK-5172 | Grazoprevir is a hepatitis C virus protease inhibitor developed for the treatment of hepatitis C. It suppresses NS3 and NS4A, which play a role in the virus splitting its polyprotein into the functional virus proteins. Grazoprevir is often used in combination with elbasvir or ribavirin. Uses: Antiviral agents. Group: Pharmaceutical. Alternative Names: Cyclopropanecarboxamide, N-[[[(1R,2R)-2-[5-(3-hydroxy-6-methoxy-2-quinoxalinyl)pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-, cyclic (1→2)-ether, (1R,2S)-; Grazoprevir; (1R,2S)-N-[[[(1R,2R)-2-[5-(3-Hydroxy-6-methoxy-2-quinoxalinyl)pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenylcyclopropanecarboxamide Cyclic (1→2)-Ether. CAS No. 1350514-68-9. Pack Sizes: 100 mg. Product ID: B2693-007134. Molecular formula: C38H50N6O9S. Mole weight: 766.91. Custom synthesis is available. Send your inquiries for more information. | London |
| Monodecarboxy piperacilloic acid | An impurity of Piperacillin, which is a broad-spectrum antibiotic used to treat serious, hospital-acquired infections in combination with the beta lactamase inhibitor tazobactam. Group: Pharmaceutical. Alternative Names: 4-Thiazolidinecarboxylic acid, 2-[[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]methyl]-5,5-dimethyl-, [2R-[2α(R*),4β]]-; α-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)benzylpenilloic acid; (2R,4S)-2-(((R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)methyl)-5,5-dimethylthiazolidine-4-carboxylic acid; Penilloic acids of piperacillin; Piperacillin EP Impurity C (2R-isomer). CAS No. 64817-23-8. Pack Sizes: 10 mg. Product ID: B2694-478852. Molecular formula: C22H29N5O6S. Mole weight: 491.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Pemetrexed Impurity D | An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Group: Pharmaceutical. CAS No. 144051-68-3. Pack Sizes: 50 mg. Product ID: B1494-478643. Molecular formula: C25H28N6O9. Mole weight: 556.54. Custom synthesis is available. Send your inquiries for more information. | London |
| Pemetrexed Impurity E Disodium Salt | An impurity of Pemetrexed, which has been approved by FDA in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug. Group: Pharmaceutical. Alternative Names: (2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid sodium. CAS No. 937370-10-0. Pack Sizes: 50 mg. Product ID: B1494-478645. Molecular formula: C20H19N5Na2O6. Mole weight: 471.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Piperacilloic Acid | An impurity of Piperacillin, which is a broad-spectrum antibiotic used to treat serious, hospital-acquired infections in combination with the beta lactamase inhibitor tazobactam. Group: Pharmaceutical. Alternative Names: Piperacillin penicilloic acid; 2-Thiazolidineacetic acid, 4-carboxy-α-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-5,5-dimethyl-, 2R-[2α[R*(R*)],4β]]-; Glycine, (2R)-N-[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]-2-phenylglycyl-2-[(2R,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]-, (2R)-; (2R,4S)-2-((R)-Carboxy((R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)methyl)-5,5-dimethylthiazolidine-4-carboxylic acid; α-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)benzylpenicilloic acid; Penicilloic acids of piperacillin. CAS No. 64817-22-7. Pack Sizes: 10 mg. Product ID: B2694-121534. Molecular formula: C23H29N5O8S. Mole weight: 535.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Plerixafor Impurity III | Plerixafor Impurity III is an impurity of Plerixafor, an immunostimulant indicated in combination with G-CSF to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with NHL and MM. Group: Pharmaceutical. Alternative Names: 1,11-Bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecane. CAS No. 771464-86-9. Pack Sizes: 5 mg. Product ID: B2694-341919. Molecular formula: C46H84N12. Mole weight: 805.24. Custom synthesis is available. Send your inquiries for more information. | London |
| Potassium guaiacolsulfonate hemihydrate | Potassium guaiacolsulfonate hemihydrate is an effective oral expectorant for acute respiratory tract infections. It helps loosen mucus and is used for coughs caused by the common cold, infections or allergies in combination with other medications. Group: Pharmaceutical. Alternative Names: Potassium 4-guaiacolsulfonate hemihydrate; potassium 4-hydroxy-3-methoxybenzene-1-sulfonate hemihydrate; Guaiacolsulfonic Acid Potassium Salt hemihydrate. CAS No. 78247-49-1. Pack Sizes: 1mg;1g;10g. Product ID: 78247-49-1. Molecular formula: 2(C7H7KO5S).H2O. Mole weight: 502.6. Custom synthesis is available. Send your inquiries for more information. | London |
| PRT062607 monohydrochloride | PRT062607, also known as PRT2607, P505-15, and BIIB057, is a novel, highly selective, and orally bioavailable small molecule SYK inhibitor (SYK IC(50) = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases. PRT062607 successfully inhibited SYK-mediated B-cell receptor signaling and decreased cell viability in NHL and CLL. Oral dosing in mice prevented BCR-mediated splenomegaly and significantly inhibited NHL tumor growth in a xenograft model. In addition, combination treatment of primary CLL cells with PRT062607 plus fludarabine produced synergistic enhancement of activity at nanomolar concentrations. PRT062607 may be a therapeutic agent for B-cell malignancies. A dose finding study in healthy volunteers has been completed. Group: Pharmaceutical. Alternative Names: 5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-, hydrochloride (1:1); PRT2607 HCl; PRT-2607 HCl; PRT 2607 HCl; RPRT062607 HCl; PRT-062607 HCl; PRT 062607 HCl; P505-15 HCl; BIIB057 HCl; BIIB 057 HCl; 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide hydrochloride. CAS No. 1370261-97-4. Pack Sizes: 10 mg. Product ID: B2693-457962. Molecular formula: C19H23N9O.HCl. Mole weight: 429.91. Custom synthesis is available. Send your inquiries for more information. | London |
| PSI 7411 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Group: Pharmaceutical. Alternative Names: 5'-Uridylic acid, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)?-; (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic acid; PSI-7411; PSI7411; 2'-Fluoro-2'-methyl(up)-uridine-5'-monophosphate; 2'-F-2'-Me(up)-UMP; Sofosbuvir Impurity 34 (GS-606965). CAS No. 1015073-43-4. Pack Sizes: 10 mg. Product ID: B2694-479716. Molecular formula: C10H14FN2O8P. Mole weight: 340.2. Custom synthesis is available. Send your inquiries for more information. | London |
| Pyronaridine | Pyronaridine is an antimalarial drug. Pyronaridine was first synthesized in 1970 and has been in clinical use in China since the 1980s. It is one of the components of the artemisinin combination therapy pyronaridine artesunate (Pyramax). Uses: Antimalarial. Group: Pharmaceutical. Alternative Names: 2-Methoxy-7-chloro-10-(3',5'-bis(pyrrolin-1-ylmethyl)-4'-hydroxyphenylamino)benzo(b)-1,5-naphthyridine;76748-86-2(Pyronaridine tetraphosphate). CAS No. 74847-35-1. Pack Sizes: 500 mg. Product ID: B0084-476596. Molecular formula: C29H32ClN5O2. Mole weight: 518.04968. Custom synthesis is available. Send your inquiries for more information. | London |
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