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| Product | Description | |
|---|---|---|
| Colchicine | 1g Pack Size. Group: Bioactive Small Molecules, Biochemicals. Formula: C22H25NO6. CAS No. 64-86-8. Prepack ID : 22115544-1g. Molecular Weight : 399.44. |  |
| Colchicine | Colchicine, a toxic plant-derived alkaloid extracted from plants of the genus Colchicum, inhibits microtubule polymerization (IC50 = 3.2 μM). It inhibits the growth of MCF-7 human breast carcinoma cells and has anti-inflammatory activity. Colchicine can lower body temperature, inhibit the respiratory center, enhance the effect of sympathomimetic drugs, constrict blood vessels, and raise blood pressure. Group: Pharmaceutical. CAS No. 64-86-8. Pack Sizes: 1 g. Product ID: BBF-04529. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Colchicine Impurities | Colchicine Impurities, integral to drug development, significantly aid in quality control and research of colchicine-based formulations. They play an essential role in addressing safety and efficacy concerns by identifying potential adverse effects, particularly in treatments for gout and familial Mediterranean fever, thereby enhancing pharmacological reliability and therapeutic success. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| gamma-Lumicolchicine | gamma-Lumicolchicine is a novel and potent isomer of ultraviolet degradation products of colchicine. Group: Pharmaceutical. CAS No. 6901-14-0. Pack Sizes: 5 mg. Product ID: B1370-069976. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| OXi-4503 | OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue. In addition, orthoquinone intermediates, metabolized from combretastatin A1 by oxidative enzymes found to be elevated levels in some tumor types, may bind to tumor cell thiol-specific antioxidant proteins and DNA, and stimulate oxidative stress by enhancing superoxide/hydrogen peroxide production. CA1 binds to tubulin at the same site as colchicine but with higher affinity. Group: Pharmaceutical. CAS No. 288847-35-8. Pack Sizes: 100 mg. Product ID: B0084-353235. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Thiocolchicoside | Thiocolchicoside is a semi-synthetic derivative of colchicine, an anti-inflammatory glycoside extracted from the flower seeds of superba gloriosa. Thiocolchicoside acts as a GABAA receptor antagonist exhibiting anti-inflammatory and analgesic activity. It is used as a muscle relaxant. Group: Pharmaceutical. CAS No. 602-41-5. Pack Sizes: 500 mg. Product ID: B0084-464811. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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