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| Product | Description | |
|---|---|---|
| Cilastatin Ammonium Salt | Cilastatin Ammonium Salt is the ammonium salt of Cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Group: Pharmaceutical. CAS No. 877674-82-3. Pack Sizes: 500 mg. Product ID: B2693-468925. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Cilastatin Impurities | Cilastatin Impurities are crucial in the quality control and formulation of cilastatin-containing pharmaceuticals. These impurities must be carefully identified and monitored to ensure the safety and efficacy of drugs used primarily in conjunction with imipenem to treat bacterial infections, enhancing renal safety and expanding antibacterial activity. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cilastatin sodium | Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Group: Pharmaceutical. CAS No. 81129-83-1. Pack Sizes: 1 g. Product ID: B0084-077802. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (4S,6S)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester | (4S,6S)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester, a predominant intermediary in the production of cilastatin in the pharmaceutical industry, boasts versatile applications. Its superior antibacterial properties make it a promising combatant in the treatment of bacterial infections. It further plays a critical role in the production of antibiotics and other biologically active compounds, justifying its pivotal place in scientific research. Group: Pharmaceutical. CAS No. 196085-85-5. Pack Sizes: 20 mg. Product ID: B2699-118526. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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