Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| Chrysophanol | Chrysophanic acid (Chrysophanol) is a natural anthraquinone with anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in other cell lines (HT7, HT29, KM12C, SW480, HCT116 and SNU-C4) with low levels of EGFR expression. Chrysophanic acid treatment in SNU-C5 cells inhibited EGF-induced phosphorylation of EGFR and suppressed activation of downstream signaling molecules, such as AKT, extracellular signal-regulated kinase (ERK) and the mammalian target of rapamycin (mTOR)/ribosomal protein S6 kinase (p70S6K). Chrysophanic acid (80 and 120 μm) significantly blocked cell proliferation when combined with the mTOR inhibitor, rapamycin. These findings offer the first evidence of anticancer activity for chrysophanic acid via EGFR/mTOR mediated signaling transduction pathway. Chrysophanol is a natural compound found in the roots and rhizomes of Rheum palmatum L. It can be used in cosmetics material. Uses: Anti-inflammatory. Group: Pharmaceutical. Alternative Names: 1,8-dihydroxy-3-methylanthracene-9,10-dione. CAS No. 481-74-3. Pack Sizes: 1 g. Product ID: NP0901. Molecular formula: C15H10O4. Mole weight: 254.24. Custom synthesis is available. Send your inquiries for more information. |  London |
| Chrysophanol 1-O-glucoside | Chrysophanol 1-O-glucoside, an inherent component of diverse botanical species, boasts of paramount attention for its noteworthy anti-inflammatory and anti-tumor potentialities that have long been professed in traditional medicine. Its multifaceted pharmacological abilities have been under the researchers' radar, warranting potential deployment in treating metabolic maladies, liver afflictions, and obesity. Besides, this natural compound may stimulate the food and cosmetics industries with its remarkable antioxidant traits. Group: Pharmaceutical. Alternative Names: 8-hydroxy-3-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione; Chrysophanol 1-glucoside. CAS No. 4839-60-5. Pack Sizes: 5 mg. Product ID: NP0916. Molecular formula: C21H20O9. Mole weight: 416.382. Custom synthesis is available. Send your inquiries for more information. | London |
| Senna Leaf Extract | Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides. Group: Pharmaceutical. Alternative Names: Senna, Cassia obovata, ext.; Senna extract; Folium Sennae Extract. CAS No. 85085-71-8. Pack Sizes: 1 kg. Product ID: B1370-138804. Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
