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Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Group: Pharmaceutical. Alternative Names: Acotiamide;MZ-338;UNII-D42OWK5383. CAS No. 185106-16-5. Pack Sizes: 100 mg. Product ID: B0084-284892. Molecular formula: C21H30N4O5S. Mole weight: 450.554. Custom synthesis is available. Send your inquiries for more information.
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Aldicarb Sulfoxide
Aldicarb sulfoxide is a metabolite and degradation product of the carbamate pesticide aldicarb. It inhibits carboxylesterase and cholinesterase in zebrafish. Second order rate constants were calculated, and it was found that aldicarb sulfone is more sensitive to hydroxide ion concentration than aldicarb sulfoxide which is more sensitive than aldicarb. Group: Pharmaceutical. Alternative Names: ALDICARB SULFOXIDE; Temik sulfoxide; 1646-87-3; Aldicarb-sulfoxide2-Methyl-2-(methylsulfinyl)propionaldehyde O-(methylcarbamoyl)oxime. CAS No. 1646-87-3. Pack Sizes: 1mg;1g;10g. Product ID: 1646-87-3. Molecular formula: C7H14N2O3S. Mole weight: 206.26. Custom synthesis is available. Send your inquiries for more information.
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Altenuene
(-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Group: Pharmaceutical. Alternative Names: (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. CAS No. 29752-43-0. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04104. Molecular formula: C15H16O6. Mole weight: 292.29. Custom synthesis is available. Send your inquiries for more information.
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(-)-Altenuene-[d6]
Labelled (-)-Altenuene. (-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BLP-008828. Molecular formula: C15H10D6O6. Mole weight: 298.32. Custom synthesis is available. Send your inquiries for more information.
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Demecarium bromide
Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals. Uses: Cholinesterase inhibitors; miotics. Group: Pharmaceutical. Alternative Names: 3,3'-[1,10-decanediylbis[(methylimino)carbonyloxy]]bis[N,N,N-trimethylbenzenaminium Bromide; (m-Hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; (m-hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; Demekarium Bromide; Demekastigmine Bromide; Frumtosnil; Humorsol. CAS No. 56-94-0. Pack Sizes: 500 mg. Product ID: B0084-071868. Molecular formula: White Solid. Mole weight: 716.59. Custom synthesis is available. Send your inquiries for more information.
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Dipivefrin hydrochloride
Dipivefrin is a prodrug of epinephrine that is hydrolyzed by cholinesterase and other esterases in the cornea to epinephrine. It reduces the density of cultured bovine primary trabecular meshwork cells. Additionally, it induces an elongated, fibroblast-like morphology and disrupts the actin cytoskeleton in bovine primary trabecular meshwork cells when used at a concentration of 103 μM. Formulations containing dipivefrin have been used alone and in combination with β-adrenergic receptor antagonists for the treatment of glaucoma. Group: Pharmaceutical. Alternative Names: Dipivefrin HCl; Dipivefrine hydrochloride; AKPro. CAS No. 64019-93-8. Pack Sizes: 1mg;1g;10g. Product ID: 64019-93-8. Molecular formula: C19H29NO5·HCl. Mole weight: 387.9. Custom synthesis is available. Send your inquiries for more information.
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Donepezil
Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Group: Pharmaceutical. Alternative Names: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE. CAS No. 120014-06-4. Pack Sizes: 50 g. Product ID: B2692-082304. Molecular formula: C24H29NO3. Mole weight: 379.49. Custom synthesis is available. Send your inquiries for more information.
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Donepezil hydrochloride
Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively. Uses: Cholinesterase inhibitors. Group: Pharmaceutical. Alternative Names: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-oneHydrochloride; Aricept; Aricept D; BNAG; Donepezil HCl; BNAG; donepezilium oxalate trihydrate; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride. CAS No. 120011-70-3. Pack Sizes: 100 mg. Product ID: NP3421. Molecular formula: C24H30ClNO3. Mole weight: 415.95. Custom synthesis is available. Send your inquiries for more information.
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Ethyl diethylcarbamate
Ethyl diethylcarbamate, a carbamate derivative, finds extensive use as an alcohol denaturant and as an intermediate for the production of pesticides and pharmaceuticals. Furthermore, it exhibits potential therapeutic effects as a cholinesterase inhibitor, offering respite in the management of myasthenia gravis, a neuromuscular disorder that is typified by muscle weakness and fatigue. Group: Pharmaceutical. Alternative Names: Diethyl urethane; Diethylcarbamic acid ethyl ester; Carbamic acid, N,N-diethyl-, ethyl ester; NSC 24699; N,N-diethyl O-ethylcarbamate. CAS No. 3553-80-8. Pack Sizes: 1 g. Product ID: B1370-130938. Molecular formula: C7H15NO2. Mole weight: 145.2. Custom synthesis is available. Send your inquiries for more information.
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Galanthamine
Galanthamine, also called Razadyne, found in GALANTHUS and other AMARYLLIDACEAE, a cholinesterase inhibitor prescribed to treat symptoms of mild to moderate Alzheimer's, enhances cholinergic function accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Uses: Treatment of alzheimer's disease. Group: Pharmaceutical. Alternative Names: NSC 100058; NSC100058; NSC-100058; BRN 0093736; BRN0093736; BRN-0093736; Galantamine; Reminyl; Lycoremine; (-)-Galanthamine; Galantamin; Lycoremin; Jilkon; Nivalin; Razadyne; Galantamina; Galanthaminum; Galantaminum; Razadyne ER; Galantaminum. CAS No. 357-70-0. Pack Sizes: 1 g. Product ID: B1370-343377. Molecular formula: C17H21NO3. Mole weight: 287.35. Custom synthesis is available. Send your inquiries for more information.
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Nobiletin
Nobiletin is a citrus flavonoid isolated from citrus peels like in tangerine, which has anti-inflammatory and anti-tumor activities. Nobiletin has anti-hemagglutination, anti-thrombosis, anti-fungal, anti-allergic, anti-cholinesterase and anti-epileptic effects. It is a carbohydrate metabolism promoter. Uses: Anticancer. Group: Pharmaceutical. Alternative Names: Hexamethoxyflavone. CAS No. 478-01-3. Pack Sizes: 1 g. Product ID: NP1887. Molecular formula: C21H22O8. Mole weight: 402.39. Custom synthesis is available. Send your inquiries for more information.
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Physostigmine salicylate
Physostigmine salicylate is a cholinesterase inhibitor that can cross blood-brain barrier. It forms slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). It has been used to improve cognitive ability and treat glaucoma. Group: Pharmaceutical. Alternative Names: [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate (2-hydroxybenzoic acid) salt. CAS No. 57-64-7. Pack Sizes: 250 mg. Product ID: B0084-028331. Molecular formula: C22H27N3O5. Mole weight: 413.5. Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine
Rivastigmine, a carbamate derivative, is a reversible cholinesterase inhibitor that is selective for the central nervous system to treat Alzheimer's Disease. Uses: Neuroprotective agents. Group: Pharmaceutical. Alternative Names: [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate; (S)-N-ethyl-3-((1-dimethyl-amino)ethyl)-N-methylphenylcarbamate; 713, ENA; 713, SDZ ENA; ENA 713; ENA 713, SDZ; ENA-713; ENA713; Exelon; Hydrogen Tartrate, Rivastigmine; rivastigmine; Rivastigmine Hydrogen Tartrate; RivastigmineTartrate; SDZ ENA 713; Tartrate, Rivastigmine Hydrogen; 123441-03-2; ENA 713 free base; (S)-3-(1-(dimethy. CAS No. 123441-03-2. Pack Sizes: 10 g. Product ID: B0084-082595. Molecular formula: C14H22N2O2. Mole weight: 250.34. Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine EP Impurity B
An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. Alternative Names: (R,S)-3-[1-(Dimethylamino)ethyl]phenyl dimethylcarbamate; RivastigMine USP RC B; Desmethyl Rivastigmine; N-Desethyl N-Methyl rac-Rivastigmine; N,N-Dimethylcarbamic acid 3-[(RS)-1-(dimethyl amino) ethyl]phenyl ester. CAS No. 25081-93-0. Pack Sizes: 10 mg. Product ID: B1370-264654. Molecular formula: C13H20N2O2. Mole weight: 236.32. Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine Impurity F
An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. Alternative Names: (αS)-3-Methoxy-N,N,α-trimethylbenzenemethanamine; (S)-1-(3-Methoxyphenyl)-N,N-dimethylethanamine; Rivastigmine EP Impurity F. CAS No. 889443-69-0. Pack Sizes: 25 mg. Product ID: B2694-479199. Molecular formula: C11H17NO. Mole weight: 179.26. Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine USP Related Compound F
An impurity of Rivastigmine, a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. Alternative Names: 3-Vinylphenyl ethyl(methyl)carbamate; 3-Ethenylphenyl ethyl(methyl)carbamate; N-Ethyl-N-methyl-3-vinylphenyl Carbamate. CAS No. 1346602-84-3. Pack Sizes: 5 g. Product ID: B2694-479202. Molecular formula: C12H15NO2. Mole weight: 205.26. Custom synthesis is available. Send your inquiries for more information.
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Thiocholine iodide
Thiocholine iodide is an important hydrolyzed product of acetylthio-choline iodide and could be used and one of the substrates of Cholinesterase. Uses: For research used only. Group: Pharmaceutical. Alternative Names: (2-Mercaptoethyl)trimethylammonium iodide (7CI); Ammonium, (2-mercaptoethyl)trimethyl-, iodide (8CI); Ethanaminium, 2-mercapto-N,N,N-trimethyl-, iodide (9CI); Cholinethiol iodide; Thiocholine iodide; TChI. CAS No. 7161-73-1. Pack Sizes: 100 mg. Product ID: B0001-149809. Molecular formula: C5H14INS. Mole weight: 247.14. Custom synthesis is available. Send your inquiries for more information.
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