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Choline alfoscerate. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 28319-77-9. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: sn-glycero-3-phosphocholine.
Cenik Chemicals
Choline bicarbonate
Choline bicarbonate. Group: Pharmaceutical. CAS No. 78-73-9. Pack Sizes: 500 g. Product ID: B1370-008933. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Choline bicarbonate
Choline bicarbonate. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 78-73-9. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: choline carbonate (1:1).
Cenik Chemicals
Choline bis(trifluoromethylsulfonyl)imde
Choline bis(trifluoromethylsulfonyl)imde. Group: Pharmaceutical. CAS No. 827027-25-8. Pack Sizes: 100 g. Product ID: B1370-274158. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Choline chloride
1kg Pack Size. Group: Quaternary Ammonium salts. Formula: (CH3)3N(Cl)CH2CH2OH. CAS No. 67-48-1. Prepack ID : 18337252-1kg. Molecular Weight : 139.62.
Choline Chloride 60%
Choline Chloride 60%, CAS 67-48-1, Vitamins. Formerly Lansdowne Chemicals
1kg Pack Size. Group: Building Blocks, Organics. Formula: C11H21NO8. CAS No. 77-91-8. Prepack ID : 90027799-1kg. Molecular Weight : 295.29.
Choline Fenofibrate
Choline Fenofibrate is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipidemia. Group: Pharmaceutical. CAS No. 856676-23-8. Pack Sizes: 5 g. Product ID: B0084-259938. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Choline Impurities
Choline Impurities act as crucial parameters in the scrutiny of choline-based formulation integrity, playing a vital role in research and quality control. Their evaluation is essential for medications addressing cognitive disorders, such as Alzheimer's, and hepatic dysfunctions, thereby enhancing therapeutic standards and aiding in the development of safer, more effective pharmaceuticals. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetylcholine-[1,1,2,2-d4] Bromide
Acetylcholine-[1,1,2,2-d4] Bromide is the labelled analogue of Acetylcholine Bromide, which is an endogenous neurotransmitter at cholinergic synapses. Group: Pharmaceutical. CAS No. 93449-31-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-011762. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetylcholine chloride-[d9]
Acetylcholine chloride-[d9] is the deuterium labelled edition of Acetylcholine chloride. Acetylcholine is an organic molecule that acts as a neurotransmitter in many organisms, including humans. Uses: Cholinergic. Group: Pharmaceutical. CAS No. 344298-95-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-001596. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetylcholine-[d13] bromide
Acetylcholine-[d13] Bromide is the labelled analogue of Acetylcholine Bromide, which is an endogenous neurotransmitter at cholinergic synapses. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-013565. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetylcholine-[d16] Bromide
Acetylcholine-[d16] Bromide is the labelled analogue of Acetylcholine Bromide, which is an endogenous neurotransmitter at cholinergic synapses. Group: Pharmaceutical. CAS No. 347841-43-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-011763. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetylcholine Impurities
Acetylcholine Impurities are significant in the biomedical industry for their role in neurotransmitter synthesis and degradation studies. They are crucial for developing and testing drugs targeting neurological disorders like Alzheimer's disease and myasthenia gravis, offering insights into cholinergic system functioning and associated therapeutic interventions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Thiocholine iodide
Thiocholine iodide is an important hydrolyzed product of acetylthio-choline iodide and could be used and one of the substrates of Cholinesterase. Uses: For research used only. Group: Pharmaceutical. CAS No. 7161-73-1. Pack Sizes: 100 mg. Product ID: B0001-149809. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acotiamide
Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Group: Pharmaceutical. CAS No. 185106-16-5. Pack Sizes: 100 mg. Product ID: B0084-284892. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Bethanechol Impurities
Bethanechol Impurities, significant in drug research, play a pivotal role in pharmaceutical quality control, especially in the development of cholinergic agent Bethanechol. Analyzing these impurities helps ensure the safety and efficacy of medications used to manage urinary retention and glaucoma, assisting researchers in improving drug synthesis and compliance with regulatory standards. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Butylphthalide (Natural)
Butylphthalide is an anti-cerebral-ischemia drug, which is first isolated from the seeds of celery, showed efficacy in animal models of stroke. It alleviates oxidative stress caused by chronic cerebral ischemia, improves cholinergic function, and inhibits amyloid beta accumulation, thereby improving cerebral neuronal injury and cognitive deficits. Uses: Antihypertensive;anti-cerebral-ischemia. Group: Pharmaceutical. CAS No. 6066-49-5. Pack Sizes: 50 mg. Product ID: B0005-464370. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Coluracetam
MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested. Group: Pharmaceutical. CAS No. 135463-81-9. Pack Sizes: 2 g. Product ID: B0084-083492. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Demecarium bromide
Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals. Uses: Cholinesterase inhibitors; miotics. Group: Pharmaceutical. CAS No. 56-94-0. Pack Sizes: 500 mg. Product ID: B0084-071868. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Donepezil
Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Group: Pharmaceutical. CAS No. 120014-06-4. Pack Sizes: 50 g. Product ID: B2692-082304. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Donepezil hydrochloride
Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively. Uses: Cholinesterase inhibitors. Group: Pharmaceutical. CAS No. 120011-70-3. Pack Sizes: 100 mg. Product ID: NP3421. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Escitalopram
Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. Uses: Serotonin uptake inhibitors; antidepressive agents, second-generation. Group: Pharmaceutical. CAS No. 128196-01-0. Pack Sizes: 500 mg. Product ID: B2693-461840. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ethyl diethylcarbamate
Ethyl diethylcarbamate, a carbamate derivative, finds extensive use as an alcohol denaturant and as an intermediate for the production of pesticides and pharmaceuticals. Furthermore, it exhibits potential therapeutic effects as a cholinesterase inhibitor, offering respite in the management of myasthenia gravis, a neuromuscular disorder that is typified by muscle weakness and fatigue. Group: Pharmaceutical. CAS No. 3553-80-8. Pack Sizes: 1 g. Product ID: B1370-130938. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Galanthamine
Galanthamine, also called Razadyne, found in GALANTHUS and other AMARYLLIDACEAE, a cholinesterase inhibitor prescribed to treat symptoms of mild to moderate Alzheimer's, enhances cholinergic function accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Uses: Treatment of alzheimer's disease. Group: Pharmaceutical. CAS No. 357-70-0. Pack Sizes: 1 g. Product ID: B1370-343377. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Nefiracetam
Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Uses: Neuroprotective agents. Group: Pharmaceutical. CAS No. 77191-36-7. Pack Sizes: 1 g. Product ID: B0084-076916. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Neostigmine Impurities
Neostigmine Impurities, associated with the synthesis of neostigmine, play a crucial role in quality control for drugs targeting myasthenia gravis and postoperative urinary retention. These impurities help ensure the efficacy and safety of cholinesterase inhibitors by providing insights into the drug's purity and stability during pharmaceutical development. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Nobiletin
Nobiletin is a citrus flavonoid isolated from citrus peels like in tangerine, which has anti-inflammatory and anti-tumor activities. Nobiletin has anti-hemagglutination, anti-thrombosis, anti-fungal, anti-allergic, anti-cholinesterase and anti-epileptic effects. It is a carbohydrate metabolism promoter. Uses: Anticancer. Group: Pharmaceutical. CAS No. 478-01-3. Pack Sizes: 1 g. Product ID: NP1887. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Physostigmine salicylate
Physostigmine salicylate is a cholinesterase inhibitor that can cross blood-brain barrier. It forms slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). It has been used to improve cognitive ability and treat glaucoma. Group: Pharmaceutical. CAS No. 57-64-7. Pack Sizes: 250 mg. Product ID: B0084-028331. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Polygalacic acid
Polygalacic Acid is a compound of the triterpenoid saponins that can promote the cholinergic system reactivity. Group: Pharmaceutical. CAS No. 22338-71-2. Pack Sizes: 5 mg. Product ID: B0005-464921. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine
Rivastigmine, a carbamate derivative, is a reversible cholinesterase inhibitor that is selective for the central nervous system to treat Alzheimer's Disease. Uses: Neuroprotective agents. Group: Pharmaceutical. CAS No. 123441-03-2. Pack Sizes: 10 g. Product ID: B0084-082595. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine-[d6] oxalate
Rivastigmine-[d6] oxalate is a labelled impurity of Rivastigmine. Rivastigmine is a parasympathomimetic or cholinergic drug for the treatment of dementia. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014089. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine Impurity F
An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. CAS No. 889443-69-0. Pack Sizes: 25 mg. Product ID: B2694-479199. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine USP Related Compound F
An impurity of Rivastigmine, a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. CAS No. 1346602-84-3. Pack Sizes: 5 g. Product ID: B2694-479202. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Solifenacin Succinate
Solifenacin is a competitive cholinergic receptor antagonist. Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class. Uses: Urological agents. Group: Pharmaceutical. CAS No. 242478-38-2. Pack Sizes: 1 g. Product ID: B2694-063823. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Tebanicline hydrochloride
Tebanicline hydrochloride is the hydrochloride salt of Tebanicline (ABT-594) which is a neuronal nicotinic acetyl-choline receptor agonist and has been described as a breakthrough inanalgesia. Group: Pharmaceutical. CAS No. 203564-54-9. Pack Sizes: 100 mg. Product ID: B1370-007298. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Tolcapone
Tolcapone functions as a selective peripheral and central COMT inhibitor, exerting no effect on adrenergic, serotonergic, or cholinergic receptors or other enzymes involved in synthesis or catabolism of catecholamines. Group: Pharmaceutical. CAS No. 134308-13-7. Pack Sizes: 250 mg. Product ID: B0084-352400. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Trospium Chloride
Trospium chloride is a competitive muscarinic cholinergic receptor antagonist. Uses: Urological agents. Group: Pharmaceutical. CAS No. 10405-02-4. Pack Sizes: 5 g. Product ID: B2693-053465. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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(±)-Vesamicol hydrochloride
(±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (Ki = 2 nM) that blocks the loading of acetylcholine into synaptic vesicles of cholinergic nerve terminals. The inhibition by Vesamicol attenuates acetylcholine neuronal signaling without direct effecys on signaling mechanisms. Group: Pharmaceutical. CAS No. 120447-62-3. Pack Sizes: 100 mg. Product ID: B1370-072516. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Y27632
Y-27632 is a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. In addition, studies show that Y-27632 increases the release of neurotransmitters from cholinergic nerves. Uses: Reprogramming, self-renewal. Group: Pharmaceutical. CAS No. 146986-50-7. Pack Sizes: 100 mg. Product ID: B1370-321602. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Zuclopenthixol Decanoate
Zuclopenthixol decanoate is a typical antipsychotic drug belonging to the thioxanthene class. lt has high affinity for both dopamine D1 and D2 receptors, for α1-adrenoceptors and 5-HT2 receptors but has no affinity for cholinergic muscarine receptors. It is used in the maintenance treatment of chronic schizophrenic patients. lt is not approved for use in the United States. It was introduced in 1962 by Lundbeck. Uses: Zuclopenthixol decanoate is used in the maintenance treatment of chronic schizophrenic patients. Group: Pharmaceutical. CAS No. 64053-00-5. Pack Sizes: 1 g. Product ID: B1370-419146. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Zuclopenthixol dihydrochloride
Zuclopenthixol dihydrochloride is an antagonist at D1 and D2 dopamine receptors. Zuclopenthixol also has high affinity for alpha1-adrenergic and 5-HT2 receptors, but it has weaker histamine H1 receptor blocking activity, and even lower affinity for muscarinic cholinergic and alpha2-adrenergic receptors. lt is the cis-isomer of clopenthixol. It is an antipsychotic drug belonging the thioxanthene class. Group: Pharmaceutical. CAS No. 58045-23-1. Pack Sizes: 100 mg. Product ID: B1370-285267. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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