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| Product | Description | |
|---|---|---|
| 1-(4-Chlorophenyl)-3-(4-fluorophenyl)thiourea | 1-(4-Chlorophenyl)-3-(4-fluorophenyl)thiourea, a chemical compound widely used in biomedical research, poses significant therapeutic potential against several diseases such as cancer, inflammation and autoimmune disorders. Existing studies have demonstrated the compound's efficacy in thwarting these health conditions. Its multifarious medicinal applications make it an interesting area of further inquiry for the biomedical research community. Group: Pharmaceutical. Alternative Names: N-(4-chlorophenyl)-N'-(4-fluorophenyl)thiourea; NSC 80538. CAS No. 370-26-3. Pack Sizes: 25 mg. Product ID: B0001-284863. Molecular formula: C13H10ClFN2S. Mole weight: 280.745. Custom synthesis is available. Send your inquiries for more information. |  London |
| 2-Chloro-3-fluoroaniline | 25g Pack Size. Group: Building Blocks, Fluorinated Products, Organics. Formula: C6H5ClFN. CAS No. 21397-08-0. Prepack ID : 22451409-25g. Molecular Weight : 145.56. |  |
| 2-Chloro-3-fluoroaniline | 5g Pack Size. Group: Building Blocks, Fluorinated Products, Organics. Formula: C6H5ClFN. CAS No. 21397-08-0. Prepack ID : 22451409-5g. Molecular Weight : 145.56. | |
| 2-Chloro-4-fluorobenzaldehyde | 2-Chloro-4-fluorobenzaldehyde Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 84194-36-5. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply. |  UK / EU / USA / Japan |
| 2-Chloro-4-fluorotoluene | 2-Chloro-4-fluorotoluene Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 452-73-3. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals suppliers. | UK / EU / USA / Japan |
| 2-Chloro-5-fluoropyridine | 2-Chloro-5-fluoropyridine. CAS No. 31301-51-6. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| 2-Chloro-6-fluorotoluene | 2-Chloro-6-fluorotoluene Uses: Pharmaceutical Research and Development. Group: Chemicals & Intermediates. CAS No. 443-83-4. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals (Formerly Melrob-Eurolabs). | UK / EU / USA / Japan |
| 3-Chloro-2-fluorobenzoic acid | 3-Chloro-2-fluorobenzoic acid Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 161957-55-7. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals suppliers (Formerly Melrob-Eurolabs). | UK / EU / USA / Japan |
| 3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene | 3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene, a crucial chemical intermediate, plays a vital role in the intricate synthesis processes of pharmaceuticals and agrochemicals. Its versatile nature allows for the creation of potent drugs aimed at combating a multitude of ailments, such as cancer and infectious diseases. Group: Pharmaceutical. Alternative Names: 443882-99-3; 2-CHLORO-1-(3-FLUOROBENZYLOXY)-4-NITROBENZENE2-Chloro-1-((3-fluorobenzyl)oxy)-4-nitrobenzene3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene2-chloro-1-[(3-fluorophenyl)methoxy]-4-nitrobenzene. CAS No. 443882-99-3. Pack Sizes: 1mg;1g;10g. Product ID: NP3185. Molecular formula: C13H9ClFNO3. Mole weight: 281.67. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Chloro-N-((3-chloro-5-fluorophenyl)carbamothioyl)benzamide | 3-Chloro-N-((3-chloro-5-fluorophenyl)carbamothioyl)benzamide is a novel chemical entity that is widely employed in scientific investigations aimed at uncovering the therapeutic potential of diverse human diseases. Recent evidence suggests that this compound may offer a promising mode of action in the treatment of select cancer types. Although ongoing research continues to elucidate its safety and effectiveness, the preliminary findings hold considerable promise for this molecule as a potentially life-saving drug candidate. Group: Pharmaceutical. Alternative Names: 3-Chloro-N-[[(3-chloro-5-fluorophenyl)amino]thioxomethyl]benzamide; Benzamide, 3-chloro-N-[[(3-chloro-5-fluorophenyl)amino]thioxomethyl]-. CAS No. 1796641-12-7. Pack Sizes: 50 mg. Product ID: B0001-284777. Molecular formula: C14H9Cl2FN2OS. Mole weight: 343.2. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Chloro-2-fluorotoluene | 4-Chloro-2-fluorotoluene Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 452-75-5. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals suppliers (Formerly Melrob-Eurolabs). | UK / EU / USA / Japan |
| 4-Fluorophenyl chloroformate | 1g Pack Size. Group: Building Blocks, Fluorinated Products, Organics. Formula: C7H4ClFO2. CAS No. 38377-38-7. Prepack ID : 90018645-1g. Molecular Weight : 174.56. | |
| 4-N-(3-Chloro-4-fluorophenyl)-7-[(3R)-oxolan-3-yl]oxyquinazoline-4,6-diamine | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. Alternative Names: (R)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine; (R)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. CAS No. 402855-03-2. Pack Sizes: 10 mg. Product ID: B2694-292473. Molecular formula: C18H16ClFN4O2. Mole weight: 374.8. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde | Lapatinib intermediate. Group: Pharmaceutical. Alternative Names: 5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde. CAS No. 231278-84-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3184. Molecular formula: C26H17ClFN3O3. Mole weight: 473.88. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate | An impurity of Prasugrel. Prasugrel is a platelet inhibitor and an irreversible antagonist of P2Y12ADP receptors that prevents the formation of blood clots. It was appoved for the treatment of acute coronary syndrome (ACS), and some cardiovascular diseasess in combination with Aspirin. Group: Pharmaceutical. Alternative Names: 5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate maleate; Prasugrel Impurity 4. CAS No. 1373350-61-8. Pack Sizes: 20 mg. Product ID: B0219-007244. Molecular formula: C24H25ClFNO7S. Mole weight: 525.972. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-(Benzyloxy)-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline | 6-(Benzyloxy)-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline (CAS# 913819-12-2 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(phenylmethoxy)-4-quinazolinamine. CAS No. 913819-12-2. Pack Sizes: 1 g. Product ID: B2699-100471. Molecular formula: C22H17ClFN3O2. Mole weight: 409.84. Custom synthesis is available. Send your inquiries for more information. | London |
| N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine | 6-Iodo-N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]quinazolin-4-amine is a chemical compound employed in the synthesis of novel anticancer agents that selectively modulate pivotal signaling cascades crucial for malignant cell growth and viability, exhibiting notable efficacy against diverse malignancies such as lung carcinoma and breast adenocarcinoma. Group: Pharmaceutical. CAS No. 231278-20-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3186. Molecular formula: C21H14ClFIN3O. Mole weight: 505.71. Custom synthesis is available. Send your inquiries for more information. | London |
| N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide | N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide is an impurity of Afatinib, which is a tyrosine kinase inhibitor used to treat non-small cell lung carcinoma (NSCLC). Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-; (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. CAS No. 439081-18-2. Pack Sizes: 500 mg. Product ID: B0084-092426. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Custom synthesis is available. Send your inquiries for more information. | London |
| O-(6-Chloro-1-hydrocibenzotriazol-1-yl)- -1,1,3,3-Tetra methyl uronium tetra fluoroborate | O-(6-Chloro-1-hydrocibenzotriazol-1-yl)- -1,1,3,3-Tetra methyl uronium tetra fluoroborate Uses: Pharmaceutical R&D. Group: Coupling Reagents. Alternative Names: TCTU. CAS No. 330641-16-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals suppliers. | UK / EU / USA / Japan |
| 2-Chloro Vonoprazan | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Group: Pharmaceutical. Alternative Names: 2-Chloro Vonoprazan; 928325-68-2; 1-(2-Chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine; 1-[2-chloro-5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine; SCHEMBL1580961; CS-0164589; 1-(2-chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine? (Vonoprazan Impurity pound(c). CAS No. 928325-68-2. Pack Sizes: 2 mg. Product ID: B2694-338779. Molecular formula: C17H15ClFN3O2S. Mole weight: 379.84. Custom synthesis is available. Send your inquiries for more information. | London |
| A-1165442 | A-1165442 is a potent, competitive and orally available modality-differentiated second-generation TRPV1 antagonist with good analgesic efficacy and a temperature-neutral profile (IC50 = 9 nM for human TRPV1). Group: Pharmaceutical. Alternative Names: A1165442; A 1165442; A-1165442; 1-[(4R)-7-chloro-2,2-bis(fluoromethyl)-3,4-dihydrochromen-4-yl]-3-(3-methylisoquinolin-5-yl)urea; 1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea. CAS No. 1221443-94-2. Pack Sizes: 1mg;1g;10g. Product ID: 1221443-94-2. Molecular formula: C22H20ClF2N3O2. Mole weight: 431.86. Custom synthesis is available. Send your inquiries for more information. | London |
| A1874 | A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. A1874 (A-1874) is a nutlin-based and BRD4-degrading PROTAC with DC50 of 32 nM (induce BRD4 degradation in cells); A1874 is more effective in inhibiting proliferation of many cancer cell lines with wild type p53 than was a corresponding VHL-utilizing PROTAC with similar potency and efficacy to degrade BRD4; demonstrates synergistic antiproliferative effect via simultaneous degradation of BRD4 and stabilization of p53. Group: Pharmaceutical. Alternative Names: A1874; A 1874; A-1874; (2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-N-(4-((1-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)carbamoyl)-2-methoxyphenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamide. CAS No. 2064292-12-0. Pack Sizes: 1mg;1g;10g. Product ID: 2064292-12-0. Molecular formula: C58H62Cl3F2N9O7S. Mole weight: 1173.59. Custom synthesis is available. Send your inquiries for more information. | London |
| A1B1 hydrochloride | A1B1 hydrochloride is a potent and orally-available chemokine CCR1 antagonist. Group: Pharmaceutical. Alternative Names: N-[5-chloro-2-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide hydrochloride. Pack Sizes: 1mg;1g;10g. Molecular formula: C23H25ClFN3O2.HCl. Mole weight: 466.38. Custom synthesis is available. Send your inquiries for more information. | London |
| AAT-008 | AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4; IC50 = 16.3 nM in a human EP4 functional assay). Group: Pharmaceutical. Alternative Names: 4-[(1S)-1-[[5-chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acid. CAS No. 847727-81-5. Pack Sizes: 1mg;1g;10g. Product ID: 847727-81-5. Molecular formula: C21H16ClFN2O4. Mole weight: 414.8. Custom synthesis is available. Send your inquiries for more information. | London |
| AB-680 ammonium | AB-680 ammonium is a highly potent, reversible and selective CD73 (an ecto-nucleotidase) inhibitor, with a Ki of 4.9 pM for hCD73, and displays >10,000-fold selectivity over related ecto-nucleotidases CD39. It has antitumor activity. Group: Pharmaceutical. Alternative Names: 6-Chloro-N-[(1S)-1-(2-fluorophenyl)ethyl]-1-{5-O-[hydroxy(phosphonomethyl)phosphoryl]-β-D-ribofuranosyl}-1H-pyrazolo[3,4-b]pyridin-4-amine ammonium (1:2). Pack Sizes: 1mg;1g;10g. Molecular formula: C20H30ClFN6O9P2. Mole weight: 614.89. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT-639 hydrochloride | ABT-639 hydrochloride is a peripherally acting and selective T-type calcium channel blocker. Group: Pharmaceutical. Alternative Names: 4-Chloro-2-fluoro-N-(2-fluorophenyl)-5-[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-ylcarbonyl]benzenesulfonamide hydrochloride (1:1); Benzenesulfonamide, 4-chloro-2-fluoro-N-(2-fluorophenyl)-5-[[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]carbonyl]-, hydrochloride (1:1). CAS No. 1235560-31-2. Pack Sizes: 1mg;1g;10g. Product ID: 1235560-31-2. Molecular formula: C20H21Cl2F2N3O3S. Mole weight: 492.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib | Afatinib irreversibly inhibits EGFR/HER2 including EGFR, EGFR(L858R), EGFR(L858R/T790M) and HER2. It is 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992; Gilotrif; Giotrif; Tovok; (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. CAS No. 850140-72-6. Pack Sizes: 500 mg. Product ID: B0084-258486. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib-[d6] | Afatinib-[d6] is the labelled analogue of Afatinib. Afatinib is a medication approved for the treatment of metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It acts via inhibiting EGFR and HER2. Group: Pharmaceutical. Alternative Names: Afatinib-d6; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6; Tovok-d6; Tomtovok-d6. CAS No. 1313874-96-2. Pack Sizes: 5 mg. Product ID: BLP-011554. Molecular formula: C24H19D6ClFN5O3. Mole weight: 491.98. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity 52 | Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC). Group: Pharmaceutical. Alternative Names: (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate; Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate. CAS No. 618061-76-0. Pack Sizes: 100 mg. Product ID: B2699-424124. Molecular formula: C24H27ClFN4O6P. Mole weight: 552.92. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity B | An analogue of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. Alternative Names: Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl; N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine; (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. CAS No. 314771-76-1. Pack Sizes: 10 mg. Product ID: B2694-466202. Molecular formula: C18H16ClFN4O2. Mole weight: 374.81. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity C | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)?amino]?-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-6-quinazolinyl]?-4-(dimethylamino)?-, (2E)?-. CAS No. 945553-91-3. Pack Sizes: 10 mg. Product ID: B2694-466206. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity D | An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. Alternative Names: (2Z)-Afatinib; Z-Afatinib; (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. CAS No. 1680184-59-1. Pack Sizes: 5 mg. Product ID: B2694-466207. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity I | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. Alternative Names: Bromo-Afatinib; (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. CAS No. 1637254-93-3. Pack Sizes: 2.5 mg. Product ID: B1370-377782. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.78. Custom synthesis is available. Send your inquiries for more information. | London |
| Alisertib | MLN8237 is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. Group: Pharmaceutical. Alternative Names: MLN8237; MLN-8237; MLN 8237; alisertib. Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-. CAS No. 1028486-01-2. Pack Sizes: 100 mg. Product ID: B2693-336876. Molecular formula: C27H20ClFN4O4. Mole weight: 518.9. Custom synthesis is available. Send your inquiries for more information. | London |
| ARS-1323 | ARS-1323 is an inhibitor of mutant K-ras G12C. Group: Pharmaceutical. Alternative Names: ARS-1323; ARS 1323; ARS1323; 6-[6-chloro-8-fluoro-4-(4-prop-2-enoylpiperazin-1-yl)-1H-quinazolin-7-ylidene]-5-fluorocyclohexa-2,4-dien-1-one. CAS No. 1698024-73-5. Pack Sizes: 5 mg. Product ID: B0084-260280. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. Custom synthesis is available. Send your inquiries for more information. | London |
| ARS-1620 | ARS-1620 is a potent and selective KRAS-G12C inhibitor. ARS-1620 achieves rapid and sustained in vivo target occupancy to induce tumor regression. Group: Pharmaceutical. Alternative Names: ARS-1620; ARS 1620; ARS1620; BCP29125; BCP 29125; BCP-29125; 6-[6-chloro-8-fluoro-4-(4-prop-2-enoylpiperazin-1-yl)-1H-quinazolin-7-ylidene]-5-fluorocyclohexa-2,4-dien-1-one sulfane. CAS No. 1698055-85-4. Pack Sizes: 5 mg. Product ID: B0084-169263. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. Custom synthesis is available. Send your inquiries for more information. | London |
| ARS-1630 | ARS-1630 is the R-enantiomer of ARS-1620. It is an inhibitor of mutant K-ras G12C. Group: Pharmaceutical. Alternative Names: ARS-1630; ARS 1630; ARS1630; (R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one. CAS No. 1698055-86-5. Pack Sizes: 5 mg. Product ID: B0084-260281. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. Custom synthesis is available. Send your inquiries for more information. | London |
| AV-412 | AV-412 is a second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhibitor AV-412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may suppress tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. This agent may be active against EGFR/HER2-expressing tumor cells that are resistant to first-generation kinase inhibitors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization. Group: Pharmaceutical. Alternative Names: AV 412; AV412; N-[4-(3-chloro-4-fluoroanilino)-7-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl]quinazolin-6-yl]prop-2-enamide. CAS No. 451492-95-8. Pack Sizes: 20 mg. Product ID: B0084-324573. Molecular formula: C27H28ClFN6O. Mole weight: 507.01. Custom synthesis is available. Send your inquiries for more information. | London |
| Avagacestat | BMS-708163 is a potent and orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP (IC50 = 0.30 nM) to Aβ40 than signaling through Notch (IC50s = 58 nM). Uses: Gamma secretase inhibitors and modulators. Group: Pharmaceutical. Alternative Names: Avagacestat; BMS 708163; (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide. CAS No. 1146699-66-2. Pack Sizes: 50 mg. Product ID: B0084-286394. Molecular formula: C20H17ClF4N4O4S. Mole weight: 520.89. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-4635 | AZD-4635 is an orally available adenosine 2A receptor (A2AR) inhibitor. Group: Pharmaceutical. Alternative Names: AZD-4635; AZD 4635; AZD4635; HTL-1071; HTL 1071; HTL1071; 6-(2-chloro-6-methylpyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine. CAS No. 1321514-06-0. Pack Sizes: 25 mg. Product ID: B0084-260293. Molecular formula: C15H11ClFN5. Mole weight: 315.736. Custom synthesis is available. Send your inquiries for more information. | London |
| BAY-218 | BAY-218, which is known as BAY-2335218, is a potent and selective small-molecule AhR inhibitor with an IC50 of 39.9 nM in human cell line. It is a new modality to counteract tumor immunosuppression. Group: Pharmaceutical. Alternative Names: BAY 218; BAY218; BAY-2335218; BAY 2335218; BAY2335218; (S)-6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide; AHR antagonist 1. CAS No. 2162982-11-6. Pack Sizes: 100 mg. Product ID: B1370-291455. Molecular formula: C20H17ClFN3O3. Mole weight: 401.82. Custom synthesis is available. Send your inquiries for more information. | London |
| BAY 41-4109 | BAY 41-4109 is a novel drug inhibiting hepatitis B virus capsid formation and replication. Group: Pharmaceutical. Alternative Names: BAY-41-4109; BAY41-4109; BAY 41-4109; BAY-414109; BAY414109; BAY 414109. methyl (4R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate. CAS No. 298708-81-3. Pack Sizes: 2 mg. Product ID: B0084-475623. Molecular formula: C18H13ClF3N3O2. Mole weight: 395.766. Custom synthesis is available. Send your inquiries for more information. | London |
| Clinafloxacin | Clinafloxacin is a fluoroquinolone antibiotic with a broad-range of antibacterial activity. It inhibits both DNA gyrase and topoisomerase IV. Group: Pharmaceutical. Alternative Names: 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. CAS No. 105956-97-6. Pack Sizes: 100 mg. Product ID: B0084-053762. Molecular formula: C17H17ClFN3O3. Mole weight: 365.79. Custom synthesis is available. Send your inquiries for more information. | London |
| Clobetasol | Clobetasol is a highly potent topical corticosteroid used to treat various skin conditions such as eczema and psoriasis. It works by reducing inflammation, redness, itching, and rashes. Clobetasol has strong anti-inflammatory, antipruritic, and vasoconstrictive properties. Uses: Anti-inflammatory agents; glucocorticoids. Group: Pharmaceutical. Alternative Names: Clobetasol Propionate EP Impurity G; (11β,16β)-21-Chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione; Clobetasol Propionate Impurity G; Dovate; Clobecort Amex; (8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one. CAS No. 25122-41-2. Pack Sizes: 20 mg. Product ID: B1726-064125. Molecular formula: C22H28ClFO4. Mole weight: 410.92. Custom synthesis is available. Send your inquiries for more information. | London |
| Clobetasol Propionate | Clobetasol propionate is a glucocorticoid that induces monooxygenase activity in vivo. It alters the structure of tight junctions in epidermis and smoothened hedgehog pathway receptor agonist. It can be used as anti-inflammatory, immunosuppressive and antimitotic agent. Active in vivo. Uses: Anti-inflammatory, immunosuppressive and antimitotic agent. Group: Pharmaceutical. Alternative Names: Clobex; Cosvate (India); Temovate (US); Olux; Tenovate; Dermovate; Dermatovate; Butavate; Movate; Novate; [17-(2'-chloroacetyl)- 9-fluoro-11-hydroxy-10,13,16-trimethyl- 3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate. CAS No. 25122-46-7. Pack Sizes: 10 g. Product ID: B0084-300298. Molecular formula: C25H32ClFO5. Mole weight: 466.974. Custom synthesis is available. Send your inquiries for more information. | London |
| Clocortolone Pivalate | Clocortolone Pivalate is a Corticosteroid Hormone Receptor Agonist. It is used for the treatment of dermatitis and is considered a medium-strength corticosteroid. It is unusual among steroids in that it contains a chlorine atom and a fluorine atom. Uses: Clocortolone pivalate is a corticosteroid hormone receptor agonist. Group: Pharmaceutical. Alternative Names: 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate, Clocortolone 21-pivalate; (6α,11β,16α)-9-Chloro-21-(2,2-dimethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-methypregna-1,4-diene-3,20-dione; CL 68; Clocortolone trimethylacetat. CAS No. 34097-16-0. Pack Sizes: 500 mg. Product ID: B0084-475656. Molecular formula: C27H36ClFO5. Mole weight: 495.04. Custom synthesis is available. Send your inquiries for more information. | London |
| delafloxacin meglumine | Delafloxacin meglumine is a fluoroquinolone that can be used to treat acute bacterial skin and skin structure infections (ABSSSI) in adult patients. Studies indicated that it has excellent tolerance and low toxicity to liver and kidney. Uses: The treatment of cute bacterial skin and skin structure infections (absssi). Group: Pharmaceutical. Alternative Names: Baxdela; 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol. CAS No. 352458-37-8. Pack Sizes: 100 mg. Product ID: B2692-007071. Molecular formula: C25H29ClF3N5O9. Mole weight: 635.978. Custom synthesis is available. Send your inquiries for more information. | London |
| Des-4-fluorobenzyl Mosapride | Des-4-fluorobenzyl Mosapride is an impurity of Mosapride. Mosapride is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. It is used as a gastroprokinetic agent. Group: Pharmaceutical. Alternative Names: Des-p-fluorobenzyl mosapride; Mosapride Impurity 5; 4-amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide. CAS No. 152013-26-8. Pack Sizes: 50 mg. Product ID: B1370-260359. Molecular formula: C14H20ClN3O3. Mole weight: 313.79. Custom synthesis is available. Send your inquiries for more information. | London |
| Eliprodil | Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia. Uses: Eliprodil is a nr2b-nmda receptor antagonist that was found to have neuroprotective activity in study of ischemia. Group: Pharmaceutical. Alternative Names: -(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, SL-82,0715; SL82,0715; SL 82,0715; SL-820715; SL820715; SL 820715; Eliprodil. CAS No. 119431-25-3. Pack Sizes: 50 mg. Product ID: B0084-359860. Molecular formula: C20H23ClFNO. Mole weight: 347.85. Custom synthesis is available. Send your inquiries for more information. | London |
| Encorafenib | Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Group: Pharmaceutical. Alternative Names: LGX818; LGX-818; LGX 818; Methyl N-[(2S)-1-[[4-[3-[5-chloro-2-fluoro-3-(methanesulfonamido)phenyl]-1-propan-2-ylpyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate. CAS No. 1269440-17-6. Pack Sizes: 150 mg. Product ID: B0084-462563. Molecular formula: C22H27ClFN7O4S. Mole weight: 540.011. Custom synthesis is available. Send your inquiries for more information. | London |
| FIPI | FIPI, a derivative of halopemide, is a potent and selective phospholipase D (PLD) inhibitor with IC50 values of 20 and 25 nM for PLD2 and PLD1 respectively. It attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. It rapidly blocks in vivo PA production with subnanomolar potency. It has good pharmacokinetic parameters in rats. It did not significantly inhibit p38 or ERK phosphorylation in bone marrow-derived macrophages stimulated with lipopolysaccharide. It prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. Group: Pharmaceutical. Alternative Names: 5-Fluoro-2-Indolyl des-Chlorohalopemide; N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide; 5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide. CAS No. 939055-18-2. Pack Sizes: 100 mg. Product ID: B2693-438324. Molecular formula: C23H24FN5O2. Mole weight: 421.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Flucloxacillin sodium | Flucloxacillin is a narrow-spectrum beta-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible Gram-positive bacteria. Group: Pharmaceutical. Alternative Names: (2S,5R,6R)-6-[[[3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium. CAS No. 1847-24-1. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03846. Molecular formula: C19H16ClFN3NaO5S. Mole weight: 475.86. Custom synthesis is available. Send your inquiries for more information. | London |
| Flumethrin | Flumethrin is a pyrethroid insecticide. It is used externally in veterinary medicine against parasitic insects and ticks on cattle, sheep, goats, horses, and dogs, and the treatment of parasitic mites in honeybee colonies. Group: Pharmaceutical. Alternative Names: [cyano-(4-fluoro-3-phenoxyphenyl)methyl] 3-[(Z)-2-chloro-2-(4-chlorophenyl)ethenyl]-2,2-dimethylcyclopropane-1-carboxylate. CAS No. 69770-45-2. Pack Sizes: 1mg;1g;10g. Product ID: 69770-45-2. Molecular formula: C28H22Cl2FNO3. Mole weight: 510.386. Custom synthesis is available. Send your inquiries for more information. | London |
| Gefitinib | Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition. Group: Pharmaceutical. Alternative Names: ZD1839; ZD 1839; ZD-1839; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine; Iressa; gefitinibum. CAS No. 184475-35-2. Pack Sizes: 5 g. Product ID: BBF-04570. Molecular formula: C22H24ClFN4O3. Mole weight: 446.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Gefitinib-[d6] | One of the isotopic labelled form of Gefitinib, which could be used as an antineoplastic agent. Group: Pharmaceutical. Alternative Names: Gefitinib-d6; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine-d6; Iressa-d6. CAS No. 1228664-49-0. Pack Sizes: 10 mg. Product ID: BLP-014883. Molecular formula: C22H18ClFN4O3D6. Mole weight: 452.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Gefitinib Impurity II | Gefitinib Impurity II. Group: Pharmaceutical. Alternative Names: N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine. CAS No. 153437-78-6. Pack Sizes: 10 mg. Product ID: B2694-471994. Molecular formula: C16H13ClFN3O2. Mole weight: 333.75. Custom synthesis is available. Send your inquiries for more information. | London |
| Ivosidenib | Ivosidenib is an oral inhibitor that specifically inhibits a mutated form of IDH1 in the cytoplasm, which blocks the proliferation of tumor cells expressing IDH1. Group: Pharmaceutical. Alternative Names: AG-120; AG 120; AG120; (2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide; Glycinamide, N2-[1-(4-cyano-2-pyridinyl)-5-oxo-L-prolyl]-2-(2-chlorophenyl)-N1-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)-, (2S)-; TIBSOVO; (S)-N-((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide. CAS No. 1448347-49-6. Pack Sizes: 100 mg. Product ID: B0084-474585. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.96. Custom synthesis is available. Send your inquiries for more information. | London |
| Lapatinib-[13C,d7] | Lapatinib-[13C,d7] is the labelled analogue of Lapatinib, a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. It can be used for the treatment of breast cancer and other solid tumours. Group: Pharmaceutical. Alternative Names: Lapatinib-13C,D7; Lapatinib Ditosylate-13C,d7; Tykerb-13C,d7; GW 572016-13C,d7; Tyverb-13C,d7; N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-[5-({[2-(13C,D3)methanesulfonyl(D4)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine. CAS No. 1210608-87-9. Pack Sizes: 1 mg. Product ID: BLP-011601. Molecular formula: C28[13C]H19D7ClFN4O4S. Mole weight: 589.09. Custom synthesis is available. Send your inquiries for more information. | London |
| Lapatinib ditosylate hydrate | Lapatinib is a synthetic, orally-active quinazoline drug with potential antitumor activity. Group: Pharmaceutical. Alternative Names: Tykerb; Tyverb; 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-, bis(4-methylbenzenesulfonate), monohydrate; Lapatinib ditosylate Monohydrate. CAS No. 388082-78-8. Pack Sizes: 1mg;1g;10g. Product ID: 388082-78-8. Molecular formula: C29H26ClFN4O4S.2C7H8O3S.H2O. Mole weight: 943.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Lapatinib Hydroxylamine | a complex used in human metabolism of lapatinib which is a dual kinase inhibitor. Group: Pharmaceutical. Alternative Names: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[hydroxy[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine. CAS No. 1360431-86-2. Pack Sizes: 10 mg. Product ID: B2694-473628. Molecular formula: C29H26ClFN4O5S. Mole weight: 597.07. Custom synthesis is available. Send your inquiries for more information. | London |
| Laropiprant | a drug used in combination with niacin to reduce blood cholesterol (LDL and VLDL) that is no longer sold. Uses: A potent, selective dp1 receptor antagonist. Group: Pharmaceutical. Alternative Names: (3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-cyclopent[b]indole-3-acetic acid. CAS No. 571170-77-9. Pack Sizes: 50 mg. Product ID: B0084-474242. Molecular formula: C21H19ClFNO4S. Mole weight: 435.91. Custom synthesis is available. Send your inquiries for more information. | London |
| LDCA | LDCA is a dual-hit metabolic modulator and inhibits LDH-A enzyme activity to stimulate apoptosis in the malignant population. LDCA can be used for the research of oncogenic progression. Group: Pharmaceutical. Alternative Names: 2,2-Dichloro-N-(3-chloro-4-fluorophenyl)acetamide. CAS No. 349106-80-5. Pack Sizes: 25 mg. Product ID: B1370-257402. Molecular formula: C8H5Cl3FNO. Mole weight: 256.49. Custom synthesis is available. Send your inquiries for more information. | London |
| LY2784544 | LY2784544 is a potent and selective JAK2 inhibitor (IC50 = 3 nM), and exhibits less potency against JAK3 (IC50 =48 nM). LY2784544 effectively inhibits JAK2V617F-driven signaling and cell proliferation in Ba/F3 cells (IC50 = 20 and 55 nM, respectively). It reduces JAK2V617F tumor cell burden with no effect on erythroid progenitor cells. Group: Pharmaceutical. Alternative Names: Gandotinib; LY-2784544; 3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine. CAS No. 1229236-86-5. Pack Sizes: 25 mg. Product ID: B0084-286443. Molecular formula: C23H25ClFN7O. Mole weight: 469.949. Custom synthesis is available. Send your inquiries for more information. | London |
| Mosapride Citrate Dihydrate | Mosapride Citrate Dihydrate is a citrate hydrate form of Mosapride, which is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. It is used as a gastroprokinetic agent. Group: Pharmaceutical. Alternative Names: Mosapride citrate salt dihydrate; 4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl ]-2-morpholinyl]methyl]benzamide citrate dihydrate; Gasmotin. CAS No. 636582-62-2. Pack Sizes: 1 g. Product ID: B0084-059885. Molecular formula: C21H25ClFN3O3·C6H8O7·2H2O. Mole weight: 650.05. Custom synthesis is available. Send your inquiries for more information. | London |
| MRTX-1719 | MRTX1719 is a potent and selective inhibitor of the PRMT5/MTA complex. Group: Pharmaceutical. Alternative Names: MRTX1719; AY4A8WD6JS; (2R)-2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile. CAS No. 2630904-45-7. Pack Sizes: 50 mg. Product ID: B1370-427889. Molecular formula: C23H18ClFN6O2. Mole weight: 464.88. Custom synthesis is available. Send your inquiries for more information. | London |
| MRTX849 | MRTX849 is a potent and mutation-selective covalent inhibitor of KRAS G12C. It maximizes inhibition by irreversibly locking the KRAS molecule in its inactive state, thereby preventing tumor cell growth which results in tumor cell death. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: MRTX-849; MRTX 849; Adagrasib; 2-((S)-4-(7-(8-Chloronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile. CAS No. 2326521-71-3. Pack Sizes: 50 mg. Product ID: B2693-342068. Molecular formula: C32H35ClFN7O2. Mole weight: 604.12. Custom synthesis is available. Send your inquiries for more information. | London |
| NVS-PAK1-1 | NVS-PAK1-1 is potent and specific allosteric PAK1 inhibitor (IC50 = 5 nM) with selective over PAK2 and a panel of 442 kinases. Group: Pharmaceutical. Alternative Names: NVS-PAK1-1; NVSPAK11; NVS PAK1 1; (3S)-3-[[8-chloro-11-(2,2-difluoroethyl)-3-fluorobenzo[b][1,4]benzodiazepin-6-yl]amino]-N-propan-2-ylpyrrolidine-1-carboxamide. CAS No. 1783816-74-9. Pack Sizes: 300 mg. Product ID: B0084-007380. Molecular formula: C23H25ClF3N5O. Mole weight: 479.93. Custom synthesis is available. Send your inquiries for more information. | London |
| Parimifasor | Parimifasor is an immunomodulator that exhibits anti-inflammatory activity. It is a potential therapy for inflammatory bowel disease (IBD). Group: Pharmaceutical. Alternative Names: 3-chloro-N-[(3-chloro-5-fluoroanilino)-[[5-(trifluoromethyl)-1H-pyrazol-3-yl]amino]methylidene]benzamide. CAS No. 1796641-10-5. Pack Sizes: 5 mg. Product ID: B0084-284779. Molecular formula: C18H11Cl2F4N5O. Mole weight: 460.214. Custom synthesis is available. Send your inquiries for more information. | London |
| Prasugrel EP Impurity E | Prasugrel EP Impurity E is an impurity of Prasugrel, which is a platelet inhibitor used to prevent formation of blood clots. Group: Pharmaceutical. Alternative Names: 5-[(1RS)-5-chloro-1-(2-fluorophenyl)-2-oxopentyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate; 2-Pentanone, 1-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-5-chloro-1-(2-fluorophenyl)-; Prasugrel chlorobutyryl analog; 1-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-5-chloro-1-(2-fluorophenyl)-2-pentanone; 2-Acetoxy-5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-[5-Chloro-1-(2-fluorophenyl)-2-oxopentyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate. CAS No. 1056459-37-0. Pack Sizes: 50 mg. Product ID: B2694-053862. Molecular formula: C20H21ClFNO3S. Mole weight: 409.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Regorafenib | Regorafenib, also known as BAY 73-4506, is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine/threonine-specific Raf kinase are involved in tumor cell signaling. Regorafenib is demonstrated to increase the overall survival of patients with metastatic colorectal cancer and has been approved by the US FDA on September 27, 2012. Uses: Antineoplastic agent. Group: Pharmaceutical. Alternative Names: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506; BAY 734506; BAY734506; BAY-734506. CAS No. 755037-03-7. Pack Sizes: 500 mg. Product ID: BBF-05856. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83. Custom synthesis is available. Send your inquiries for more information. | London |
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