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| Product | Description | |
|---|---|---|
| Cathepsin S inhibitor | Cathepsin S is expressed in antigen-presenting cells and plays a role in invariant chain processing and major histocompatibility complex class II (MHCII) antigen presentation leading to CD4+ T-cell activation. An oral Cathepsin S inhibitor that blocks MHCII antigen presentation could result in a T-cell-selective immunosuppressant agent with improved safety over the current standard of care for the treatment of rheumatoid arthritis, psoriasis, multiple sclerosis and other autoimmune-based inflammatory diseases. Group: Pharmaceutical. Alternative Names: LY3000328; LY-3000328; LY 3000328. Cathepsin S inhibitor. CAS No. 1373215-15-6. Pack Sizes: 10 mg. Product ID: B0084-463202. Molecular formula: C25H29FN4O5. Mole weight: 484.52. Custom synthesis is available. Send your inquiries for more information. |  London |
| Odanacatib | Odanacatib, also known as MK-0822, is an inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K, which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Cathepsin K, a tissue-specific cysteine protease that catalyzes degradation of bone matrix proteins such as collagen I/II, elastin, and osteonectin plays an important role in osteoclast function and bone resorption. Uses: For research used only. Group: Pharmaceutical. Alternative Names: MK0822; MK-0822; MK 0822; Odanacatib. CAS No. 603139-19-1. Pack Sizes: 100 mg. Product ID: B0084-095375. Molecular formula: C25H27F4N3O3S. Mole weight: 525.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Ulinastatin | Ulinastatin is an acid-resistant protease inhibitor derived from human urine, acting as a potent anti-inflammatory agent. It was shown to inhibit the activities of a variety of enzymes, including trypsin, chymotrypsin, thrombin, kallikrein, plasmin, elastase, cathepsin, lipase, hyaluronidase, factors IXa, Xa, XIa, and XlIa, and polymorphonuclear leukocyte elastase. Group: Pharmaceutical. Alternative Names: Urinastatin; 2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-furanyl)-. CAS No. 80449-31-6. Pack Sizes: 1 g. Product ID: B2693-135299. Molecular formula: C13H16O3. Mole weight: 220.26. Custom synthesis is available. Send your inquiries for more information. | London |
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