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| Product | Description | |
|---|---|---|
| BUTAN-1-OL | BUTAN-1-OL, Suppliers of UK laboratory chemicals wanted |  |
| Fexofenadine EP Impurity C | Fexofenadine EP Impurity C is an impurity of Fexofenadine, which is a histamine H1 receptor antagonist used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Group: Pharmaceutical. Alternative Names: Fexofenadine Hydrochloride EP impurity C; (1RS)-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]-1-[4-(1-methylethyl)phenyl]butan-1-ol; Fexofenadine Decarboxylated Degradation Product; Decarboxy Fexofenadine; 4-(Hydroxydiphenylmethyl)-α-[4-(1-methylethyl)phenyl]-1-piperidinebutanol; 1-Piperidinebutanol, 4-(hydroxydiphenylmethyl)-α-[4-(1-methylethyl)phenyl]-; Fexofenadine impurity C; (±)-4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl]-isopropylbenzene; Fexofenadine Decarboxylated degradant. CAS No. 185066-37-9. Pack Sizes: 25 mg. Product ID: B1370-471581. Molecular formula: C31H39NO2. Mole weight: 457.66. Custom synthesis is available. Send your inquiries for more information. |  London |
| Seliciclib | Seliciclib is an orally bioavailable, small-molecule cyclin-dependent kinase (CDK) inhibitor with potential proapoptotic and antineoplastic activities. Seliciclib primarily inhibits CDK2/E, CDK2/A, CDK7 and CDK9 by competing for their ATP binding sites, leading to a disruption of cell cycle progression. In addition, this agent appears to interfere with CDK-mediated phosphorylation of the carboxy-terminal domain of RNA polymerase II, inhibiting RNA polymerase II-dependent transcription, which may result in the down-regulation of antiapoptotic proteins such as induced myeloid leukemia cell differentiation protein Mcl-1. CDKs, serine/threonine kinases that play an important role in cell cycle regulation, are overexpressed in various malignancies. Mcl-1 belongs to the Bcl-2 family of antiapoptotic proteins and is a protein crucial to the survival of a range of tumor cell types. Group: Pharmaceutical. Alternative Names: R-roscovitine; Roscovitin; Roscovitine; CYC202; CYC202; CYC 202; (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol. CAS No. 186692-46-6. Pack Sizes: 100 mg. Product ID: B1370-086385. Molecular formula: C19H26N6O. Mole weight: 354.44. Custom synthesis is available. Send your inquiries for more information. | London |
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