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| Product | Description | |
|---|---|---|
| Acalabrutinib | Acalabrutinib, also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. It inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. Group: Pharmaceutical. CAS No. 1420477-60-6. Pack Sizes: 250 mg. Product ID: B0084-470855. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Acalabrutinib-[d4] | Acalabrutinib-[d4] is a labelled version of Acalabrutinib. Acalabrutinib, also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. It inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BLP-003188. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ACP-5862 | ACP-5862 is a metabolite of Acalabrutinib, a second-generation BTK inhibitor used as a medication indicated for the treatment of non-Hodgkin lymphoma known as mantle cell lymphoma. Group: Pharmaceutical. CAS No. 2230757-47-6. Pack Sizes: 1 mg. Product ID: B2694-338759. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AVL-292 | AVL-292, also known as CC-292, is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. Uses: Protein kinase inhibitors. Group: Pharmaceutical. CAS No. 1202757-89-8. Pack Sizes: 1 g. Product ID: B2693-462475. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-986195 | BMS-986195 is a Bruton's tyrosine kinase (BTK) inhibitor with IC50 of 0.1 nM. Group: Pharmaceutical. CAS No. 1912445-55-6. Pack Sizes: 200 mg. Product ID: B1370-057810. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CGI1746 | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Group: Pharmaceutical. CAS No. 910232-84-7. Pack Sizes: 100 mg. Product ID: B0084-430556. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDC-0853 | GDC-0853 is a Bruton's tyrosine kinase (BTK) inhibitor originated by Genentech. GDC-0853 can inhibit the activity of BTK and prevent the activation of the B-cell antigen receptor (BCR) signaling pathway. This leads to the inhibition of the growth of malignant B-cells that overexpress BTK. Phase III clinical trials for the treatment of Multiple sclerosis and Phase II clinical trials for the treatment of Chronic urticaria and Systemic lupus erythematosus are on-going. Uses: Rheumatoid arthritis; autoimmune disorders. Group: Pharmaceutical. CAS No. 1434048-34-6. Pack Sizes: 100 mg. Product ID: B2693-475436. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Olmutinib | Olmutinib, also called as HM61713 and BI-1482694, is an orally available, mutant-selective third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) that is being developed for treatment of advanced and metastatic EGFR mutation-positive non-small cell lung cancer (NSCLC). In May 2016, olmutinib received its first global approval in South Korea for the treatment of EGFR T790M mutation-positive lung cancer. Olmutinib is also a potent small molecule inhibitor of Bruton's tyrosine kinase (BTK). Group: Pharmaceutical. CAS No. 1353550-13-6. Pack Sizes: 200 mg. Product ID: B0084-470842. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ONO-4059 | ONO-4059, a BTK inhibitor, has been found to have potential effect against sorts of malignancies by influencing the B-cell development. It is currently under Phase II trail to study its effect against Chronic lymphocytic leukaemia. IC50: 2.2 nM. Group: Pharmaceutical. CAS No. 1351636-18-4. Pack Sizes: 100 mg. Product ID: B2693-474503. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ONO-4059 (hydrochloride) | ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model. Group: Pharmaceutical. CAS No. 1439901-97-9. Pack Sizes: 50 mg. Product ID: B0084-474577. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pirtobrutinib | Pirtobrutinib is a Bruton's tyrosine kinase (BTK) inhibitor and antineoplastic agent. Group: Pharmaceutical. CAS No. 2101700-15-4. Pack Sizes: 1 g. Product ID: B1370-372922. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-Ibrutinib | (S)-Ibrutinib is a highly selective Bruton's tyrosine kinase (Btk) irreversible inhibitor. Group: Pharmaceutical. CAS No. 936563-97-2. Pack Sizes: 10 mg. Product ID: B1370-472300. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Zanubrutinib | Zanubrutinib is a potent and irreversible BTK inhibitor. It is used as a medication for the treatment of Chronic Lymphocytic Leukemia. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 1691249-45-2. Pack Sizes: 100 mg. Product ID: B2693-292413. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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