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| Product | Description | |
|---|---|---|
| 1-Bromo-3-chloro-5,5-dimethylhydantoin (BCDMH) | 100g Pack Size. Group: Building Blocks, Organics. Formula: C5H6BrClN2O2. CAS No. 16079-88-2. Prepack ID : 75611742-100g. Molecular Weight : 241.47. |  |
| 3-Bromo-o-xylene | 3-Bromo-o-xylene is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. Group: Pharmaceutical. Alternative Names: 2,3-Dimethylbromobenzene; 3-Bromo-1,2-dimethylbenzene; Benzene, 1-bromo-2,3-dimethyl-; Xylylbromid. CAS No. 576-23-8. Pack Sizes: 1 kg. Product ID: B1370-449773. Molecular formula: C8H9Br. Mole weight: 185.06. Custom synthesis is available. Send your inquiries for more information. |  London |
| ABBV-744 | ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers. Group: Pharmaceutical. Alternative Names: N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide. CAS No. 2138861-99-9. Pack Sizes: 1mg;1g;10g. Product ID: 2138861-99-9. Molecular formula: C28H30FN3O4. Mole weight: 491.55. Custom synthesis is available. Send your inquiries for more information. | London |
| ACBI1 | ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. Group: Pharmaceutical. Alternative Names: ACBI 1; ACBI-1; (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide. CAS No. 2375564-55-7. Pack Sizes: 1mg;1g;10g. Product ID: 2375564-55-7. Molecular formula: C49H58FN9O7S. Mole weight: 936.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Arbidol hydrochloride | Arbidol is an antiviral agent used for the treatment of influenza infection in Russia and China. It has been used against influenza A and B viruses, and hepatitis C virus (HCV). It has been shown that ARB could inhibit COVID-19 infection through interfering the release of SARS-CoV-2 from intracellular vesicles. It can be used to treat trypanosomiasis in livestock. Group: Pharmaceutical. Alternative Names: Arbidol HCl; Umifenovir hydrochloride; 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester Hydrochloride. CAS No. 131707-23-8. Pack Sizes: 1 g. Product ID: NP3436. Molecular formula: C22H26BrClN2O3S. Mole weight: 513.88. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD 5153 | AZD5153 is a potent, selective, and orally available inhibitor of the bromodomain and extraterminal (BET). It can simultaneously bind two bromodomains in BRD4 with the IC50 value of 5 nM, which has been shown to increase antitumor activity in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B cell lymphoma. AZD5153 also shows enhanced potency as a result of bivalent binding and a clear correlation between BRD4 activity and cellular potency. Group: Pharmaceutical. Alternative Names: AZD-5153; AZD5153; (R)-4-(2-(4-(1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)-1,3-dimethylpiperazin-2-one. CAS No. 1869912-39-9. Pack Sizes: 25 mg. Product ID: B1370-291088. Molecular formula: C25H33N7O3. Mole weight: 479.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Bedaquiline fumarate | Bedaquiline fumarate is an anti-tuberculosis drug which selectively inhibits the mycobacterial energy metabolism and found to be effective against all states of Mycobacterium tuberculosis. It possesses a unique mechanism of action that disrupts the activity of the mycobacterial adenosine triphosphate synthase. It has an excellent in vitro activity against Mycobacterium tuberculosis, including multidrug resistant M tuberculosis, however, its side effect profile limits its use against MDR-TB when no other effective regimen can be provided. Uses: Antitubercular agents. Group: Pharmaceutical. Alternative Names: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol fumarate. CAS No. 845533-86-0. Pack Sizes: 200 mg. Product ID: B0084-463644. Molecular formula: C36H35BrN2O6. Mole weight: 671.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Bromisoval | Bromisoval is a sedative and mild hypnotic with potentially toxic effects. Group: Pharmaceutical. Alternative Names: Butanamide, N-(aminocarbonyl)-2-bromo-3-methyl-; N-(Aminocarbonyl)-2-bromo-3-methylbutanamide; Urea, (2-bromo-3-methylbutyryl)-; (2-Bromo-3-methylbutanoyl)urea; (RS)-2-Bromoisovalerylurea; (±)-Bromisoval; (α-Bromoisovaleryl)urea; 2-Bromo-3-methylbutyrylurea; 2-Bromoisovalerylurea; Abroval; Alluval; Alural; Bromaral; Bromcarbamide; Bromisovalerylurea; Bromizoval; Bromoval; Bromovalerocarbamide; Bromovaleroylurea; Bromural; Bromvalerylurea; Brovalin; BVU; Calmotin; Dagrabromyl; Dibroluur; Dormigene; Isobromyl; Pivadorm; Pivadorn; Somnurol; Upiol; Uvaleral; α-Bromisovalerylurea; α-Bromo-β-dimethylpropanoylurea; α-Bromoisovaleric acid ureide; α-Bromoisovaleroylurea. CAS No. 496-67-3. Pack Sizes: 1mg;1g;10g. Product ID: 496-67-3. Molecular formula: C6H11BrN2O2. Mole weight: 223.07. Custom synthesis is available. Send your inquiries for more information. | London |
| Bromothricin | It is a directed biosynthetic analogue of chlorothricin. It is produced by a chlorothricin-producing strain of streptomyces antibioticus using media supplemented with potassium bromide. It exhibits similar properties to chlorothricin. Group: Pharmaceutical. Alternative Names: (4S,4aS,6aR,11E,12aR,15R,16aS,21aR,21bR)-4-[[4-O-[3-O-(3-bromo-6-methoxy-2-methylbenzoyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1,2,3,4,4a,6a,7,8,9,10,12a,15,16,21,21a,21b-hexadecahydro-22-hydroxy-15,21a-dimethyl-18,21-dioxo-18H-16a,19-metheno-16aH-benzo[e]naphtho[2,1-m][1,4]dioxacyclopentadecin-14-carboxylic acid. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04218. Molecular formula: C50H63BrO16. Mole weight: 999.93. Custom synthesis is available. Send your inquiries for more information. | London |
| Citalopram EP Impurity F (Oxalate salt form) | An impurity of Citalopram. Citalopram is a selective serotonin reuptake inhibitor (SSRI) used as an antidepressant drug. It was approved by FDA for the treatment of major depression. Group: Pharmaceutical. Alternative Names: SCHEMBL5188469; CTK7I3850; 3-[(1R)-5-Bromo-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl]-N,N-dimethylpropan-1-amine Hydrogen Oxalate; 3-[5-bromo-1-(4-fluorophenyl)-3H-2-benzofuran-1-yl]-N,N-dimethylpropan-1-amine;oxalic acid; 5-BROMO-1-(3-DIMETHYLAMINOPROPYL)-1-(4-FLUOROPHENYL)-1,3-DIHYDROISOBENZOFURAN OXALATE. CAS No. 64372-43-6. Pack Sizes: 100 mg. Product ID: B0211-007220. Molecular formula: C21H23BrFNO5. Mole weight: 468.319. Custom synthesis is available. Send your inquiries for more information. | London |
| Embramine | An antihistaminic. Group: Pharmaceutical. Alternative Names: 2-[1-(4-bromophenyl)-1-phenylethoxy]-N,N-dimethylethanamine; bromadryl; embramine; embramine hydrochloride; mebrophenhydramine. CAS No. 3565-72-8. Pack Sizes: 1mg;1g;10g. Product ID: 3565-72-8. Molecular formula: C18H22BrNO. Mole weight: 348.28. Custom synthesis is available. Send your inquiries for more information. | London |
| Etravirine-[d4] | Etravirine-[d4] is the labelled analogue of Etravirine, which is a drug used for the treatment of HIV and a non-nucleoside reverse transcriptase inhibitor (NNRTI). Uses: The labeled form of etravirine is an inhibitor of hiv reverse transcriptase and could be used in the treatment of hiv infection. Group: Pharmaceutical. Alternative Names: Etravirine D4; 4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile-d4; Intelence-d4; R 165335-d4; TMC 125-d4. CAS No. 1142095-93-9. Pack Sizes: 1 mg. Product ID: BLP-011533. Molecular formula: C20H11D4BrN6O. Mole weight: 439.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Geranyl bromide | Geranyl bromide (CAS# 6138-90-5) is a chemical reagent used in the synthesis of natural and semisynthetic napthoquinones showing growth inhibitory activity for cancer cell lines. Also used in the synthesis of saicylic acid derivatives showing antimicrobial activity. Group: Pharmaceutical. Alternative Names: (2E)-1-bromo-3,7-dimethylocta-2,6-diene. CAS No. 6138-90-5. Pack Sizes: 500 g. Product ID: B2699-322862. Molecular formula: C10H17Br. Mole weight: 217.15. Custom synthesis is available. Send your inquiries for more information. | London |
| I-BET151 | I-BET151 is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. It was shown to induce early cell cycle arrest and apoptosis in human and mouse MLL-fusion leukemia cell lines. Group: Pharmaceutical. Alternative Names: GSK1210151A; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one. CAS No. 1300031-49-5. Pack Sizes: 25 mg. Product ID: B0084-457872. Molecular formula: C23H21N5O3. Mole weight: 415.453. Custom synthesis is available. Send your inquiries for more information. | London |
| NEO2734 | NEO2734 is an orally active dual inhibitor of p300/CBP and BET bromodomain with IC50 of both <30 nM. NEO2734 efficiently reduced the viability of AML cell lines and primary AML cells by inducing apoptosis. Group: Pharmaceutical. Alternative Names: EP31670; EP 31670; 1,3-Dimethyl-5-(2-(tetrahydro-2H-pyran-4-yl)-1-(2-(trifluoromethoxy)ethyl)-1H-benzo[d]imidazol-6-yl)pyridin-2(1H)-one. CAS No. 2081072-29-7. Pack Sizes: 100 mg. Product ID: B1370-381461. Molecular formula: C22H24F3N3O3. Mole weight: 435.44. Custom synthesis is available. Send your inquiries for more information. | London |
| NI 57 | NI 57 is a BRPF bromodomain inhibitor. It is selective for BRPFs over other bromodomains. Group: Pharmaceutical. Alternative Names: NI-57; NI 57; NI57. 4-Cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)-2-methoxybenzene-1-sulfonamide. CAS No. 1883548-89-7. Pack Sizes: 10 mg. Product ID: B1370-138724. Molecular formula: C19H17N3O4S. Mole weight: 383.42. Custom synthesis is available. Send your inquiries for more information. | London |
| PLX51107 | PLX51107 is a potent and selective BET inhibitor with modest preference for bromodomain-1 (BD1) versus bromodomain-2 (BD2). It blocks the interaction mediated by the four BET family proteins. Group: Pharmaceutical. Alternative Names: (S)-4-(6-(3,5-dimethylisoxazol-4-yl)-1-(1-(pyridin-2-yl)ethyl)-1H-pyrrolo[3,2-b]pyridin-3-yl)benzoic acid; PLX 51107; PLX-51107. CAS No. 1627929-55-8. Pack Sizes: 50 mg. Product ID: B1370-291085. Molecular formula: C26H22N4O3. Mole weight: 438.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Sulbactam EP Impurity C | An impurity of Sulbactam. Sulbactam is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic. Group: Pharmaceutical. Alternative Names: 6-Bromopenicillanic acid sulfone (USP); Brobactam S,S-Dioxide; 6beta-Bromopenicillanic acid 1,1-dioxide; (2S,5R,6R)-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide. CAS No. 75527-87-6. Pack Sizes: 10 mg. Product ID: B1370-275401. Molecular formula: C8H10BrNO5S. Mole weight: 312.14. Custom synthesis is available. Send your inquiries for more information. | London |
| Sulbactam EP Impurity D | An impurity of Sulbactam. Sulbactam is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic. Uses: Beta-lactamase inhibitors. Group: Pharmaceutical. Alternative Names: Brobactam; 6-Bromopenicillanic Acid; [2S-(2α,5α,6β)]-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid. CAS No. 26631-90-3. Pack Sizes: 25 mg. Product ID: B1370-285383. Molecular formula: C8H10BrNO3S. Mole weight: 280.14. Custom synthesis is available. Send your inquiries for more information. | London |
| TBAJ-876 | A potent anti-tuberculosis agent via inhibiting the mycobacterial F-ATP synthase. Group: Pharmaceutical. Alternative Names: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol. CAS No. 2332841-25-3. Pack Sizes: 100 mg. Product ID: B1370-381731. Molecular formula: C31H37BrN4O7. Mole weight: 657.55. Custom synthesis is available. Send your inquiries for more information. | London |
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