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5g Pack Size. Group: Amino Acids. Formula: C20H33N3O8. CAS No. 30189-36-7. Prepack ID : 59542689-5g. Molecular Weight : 443.49.
BOC-L-Lysine-OH
5g Pack Size. Group: Amino Acids. Formula: C11H22N2O4. CAS No. 13734-28-6. Prepack ID : 15829974-5g. Molecular Weight : 246.3.
Fmoc-Lys(Boc)-OH
5g Pack Size. Group: Amino Acids. Formula: C26H32N2O6. CAS No. 71989-26-9. Prepack ID : 90029040-5g. Molecular Weight : 468.54.
Fmoc-N-Me-D-Lys(Boc)-OH
Fmoc-N-Me-D-Lys(Boc)-OH is a multifaceted chemical agent that is employed in the synthetic production of proteins and peptides. This chemical is highly valued in the medical industry for its efficacy in treating infectious diseases and cancers. Scientists have also harnessed its potential for biochemical research pertaining to the design of pharmaceuticals directed towards targeted proteins. Group: Pharmaceutical. CAS No. 1793105-27-7. Pack Sizes: 5 g. Product ID: BAT-008511. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Nα-Boc-Nε-Z-D-lysine (CAS 55878-47-2). Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 55878-47-2. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications.
Cenik Chemicals
1-Stearoyl-sn-glycero-3-phosphocholine
1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated 18:0 lysophosphatidylcholine found in plasma and oxidized LD. Uses: 1-stearoyl-sn-glycero-3-phosphocholine can be used in lipid metabolism studies. Group: Pharmaceutical. CAS No. 19420-57-6. Pack Sizes: 100 mg. Product ID: BAT-006370. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2'-Hydroxydaidzein
2'-Hydroxydaidzein is a natural flavonoid found in the herbs of Crotalaria pallida. It shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils. Uses: Phytoalexin. Group: Pharmaceutical. CAS No. 7678-85-5. Pack Sizes: 1 mg. Product ID: NP2159. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
4-Penten-1-amine
In the presence of sugars, lysine, similarly to asparagine and phenylalanine, can undergo carbonyl-assisted decarboxylative deamination reaction to generate pent-4-en-1-amine, the counterpart of acrylamide. Group: Pharmaceutical. CAS No. 22537-07-1. Pack Sizes: 5 g. Product ID: B1370-309863. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
A-366
A-366 is a peptide-competitive inhibitor of the G9a/GLP histone lysine methyltransferase (IC50 = 3.3 nM) and is approximately 1000-fold selective over other methyltransferases. Group: Pharmaceutical. CAS No. 1527503-11-2. Pack Sizes: 100 mg. Product ID: B2693-474604. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH
Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH is a very efficient and selective FRET substrate for human cathepsin B (Km = 5.9 μM, kcat = 43 s-1, kcat/Km = 7288 mM-1s-1), with kcat/Km values of 133.3, 100, 32, 17, and 75 mM-1s-1 for cathepsin K, L, V, X, and cruzain, respectively. Group: Pharmaceutical. CAS No. 827044-38-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015347. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Arg-Gly-Lys(Ac)-AMC
Ac-Arg-Gly-Lys(Ac)-AMC is a fluorogenic substrate for the determination of histone deacetylase (HDAC) activity in a two-step enzymatic reaction. Group: Pharmaceutical. CAS No. 660846-97-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015320. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Arg-Gly-Lys-AMC
Ac-Arg-Gly-Lys-AMC is a control for the two step histone deacetylase assay with Ac-Arg-Gly-Lys(Ac)-AMC. It corresponds to the product of the deacetylase reaction, which is subsequently cleaved by trypsin. Group: Pharmaceutical. CAS No. 660846-99-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015345. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a sensitive fluorescent (FRET) peptide substrate for cathepsin D. This enzyme degrades extracellular matrix components and may promote the spread of tumor cells. High levels of active cathepsin D were found in senile plaques in the brains of Alzheimer's patients. Group: Pharmaceutical. CAS No. 400716-78-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014426. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Gly-Ala-Lys(Ac)-AMC
Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate used to measure histone deacetylase class I (HDAC 1, 2, 3 and 8) and class II (HDAC 6 and 10) activity in protease coupling assays. Ac-GAK-AM is formed from lysine deacetylation catalyzed by HDAC. Group: Pharmaceutical. CAS No. 577969-56-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015374. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Gly-Ala-Lys-AMC
Ac-Gly-Ala-Lys-AMC is the control peptide for protease-coupled histone deacetylase (HDAC) assay with Ac-Gly-Ala-Lys(Ac)-AMC. Group: Pharmaceutical. CAS No. 1926163-46-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014588. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
AC-Leu-val-lys-aldehyde
AC-Leu-val-lys-aldehyde showed a stronger inhibition of cathepsin B (IC50 = 4 nM) than leupeptin (IC50 = 0.31 μM). Group: Pharmaceutical. CAS No. 147600-40-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015917. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Lys-AMC
Ac-Lys-AMC, also known as MAL, is a fluorescent substrate for histone deacetylases (HDACs). Group: Pharmaceutical. CAS No. 156661-42-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015583. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Lys-D-Ala-D-Ala-OH
Ac-Lys-D-Ala-D-Ala-OH. Group: Pharmaceutical. CAS No. 28845-97-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-004917. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Lys-D-Ala-D-lactic acid acetate
Ac-Lys-D-Ala-D-lactic acid acetate. Group: Pharmaceutical. CAS No. 282729-62-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014989. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Lys(Fmoc)-OH
Ac-Lys(Fmoc)-OH. Group: Pharmaceutical. CAS No. 148101-51-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015307. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Lys-Gln-Leu-Arg-AFC
Ac-Lys-Gln-Leu-Arg-AFC is the optimal substrate for human Hepsin, because KQLR/VVNG corresponds to its cleavage site. Excitation at 395-400 nm, emission at 495-505 nm. Hepsin is a membrane-anchored serine protease that is overexpressed in ovarian, prostate cancer and renal cell carcinomas, and therefore can be used as a prognostic marker. Group: Pharmaceutical. CAS No. 1802078-38-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014545. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Phe-Lys-OH
Ac-Phe-Lys-OH. Group: Pharmaceutical. CAS No. 14287-21-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015834. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-Val-Tyr-Lys-NH2
Ac-Val-Tyr-Lys-NH2. Group: Pharmaceutical. CAS No. 884009-99-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014742. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
AMI-1
AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Group: Pharmaceutical. CAS No. 20324-87-2. Pack Sizes: 50 mg. Product ID: B2693-087022. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
BMS 986020
BMS 986020 is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist with an IC50 value less than 300 nM for human LPA1 expressing CHO cells. It inhibits bile acid and phospholipid transporters with IC50s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS 986020 is used for the treatment of idiopathic pulmonary fibrosis (IPF). Group: Pharmaceutical. CAS No. 1257213-50-5. Pack Sizes: 100 mg. Product ID: B2693-292060. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Complanatuside A
Complanatuside A, a flavonoid compound, is isolated from Astragalus complanatus and Lysimachia christinae. Astragalus complanatus R.Brown is a widely used herbal material in traditional Chinese medicine. The total flavonoid (TF) is an active fraction extracted from seeds of Astragalus complanatus R.Brown. Previous studies performed in animals have demonstrated the antihypertensive efficacy of the TF. Group: Pharmaceutical. CAS No. 116183-66-5. Pack Sizes: 20 mg. Product ID: B0005-479850. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS. Group: Pharmaceutical. CAS No. 730985-86-1. Pack Sizes: 5 mg. Product ID: BAT-014236. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
D-Ala-Lys-AMCA
D-Ala-Lys-AMCA is a proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. Group: Pharmaceutical. CAS No. 375822-19-8. Pack Sizes: 1 mg. Product ID: BAT-006256. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Deoxynojirimycin
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase. Group: Pharmaceutical. CAS No. 19130-96-2. Pack Sizes: 250 mg. Product ID: BBF-01829. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
DiAzKs hydrochloride
DiAzKs is a diazirine-containing lysine amino acid and is a photo-cross-linker used to crosslink protein-protein interactions in vitro and in living cells. Group: Pharmaceutical. CAS No. 2421187-79-1. Pack Sizes: 50 mg. Product ID: BAT-014390. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
D-Lys(20)-Semaglutide
D-Lys(20)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B1370-449833. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Dodecyl b-D-glucopyranoside
Dodecyl b-D-glucopyranoside: A surfactant commonly used in the biomedical industry for various applications. It is utilized in drug formulation and gene delivery systems due to its ability to solubilize hydrophobic drugs. Additionally, it plays a crucial role in cell lysis, protein extraction, and enzyme stabilization. It is also employed in biochemistry and biotechnology research for the purification and analysis of glycoproteins and glycolipids. Group: Pharmaceutical. CAS No. 59122-55-3. Pack Sizes: 5 g. Product ID: B2693-095117. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Dodecylphosphocholine
Dodecylphosphocholine is a structural analogue of lauroyl lysophosphatidylcholine which is more stable to hydrolytic degradation. Group: Pharmaceutical. CAS No. 29557-51-5. Pack Sizes: 1 g. Product ID: B0001-062762. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
D-Val-Leu-Lys 4-nitroanilide dihydrochloride
D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Group: Pharmaceutical. CAS No. 62354-43-2. Pack Sizes: 5 mg. Product ID: BAT-014255. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
EPZ-6438
EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity. EPZ-6438 induces apoptosis and differentiation specifically in SMARCB1-deleted MRT cells. Treatment of xenograft-bearing mice with EPZ-6438 leads to dose-dependent regression of MRTs with correlative diminution of intratumoral trimethylation levels of lysine 27 on histone H3, and prevention of tumor regrowth after dosing cessation. These data demonstrate the dependency of SMARCB1 mutant MRTs on EZH2 enzymatic activity and portend the utility of EZH2-targeted drugs for the treatment of these genetically defined cancers. EPZ-6438 is currently in clinical trials. Group: Pharmaceutical. CAS No. 1403254-99-8. Pack Sizes: 1 g. Product ID: B0084-462339. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
FIN56
FIN56 is a specific inducer of ferroptosis and causes the loss of GPX4 activity in cell lysates. Group: Pharmaceutical. CAS No. 1083162-61-1. Pack Sizes: 25 mg. Product ID: B0084-007264. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Fmoc-D-Lys(Dde)-OH
Fmoc-D-Lys(Dde)-OH, a vital reagent for peptide synthesis, restricts the D-Lysine residue for selective introduction of D-amino acids into the peptide chains. Moreover, the Dde protection group enables mild deprotection under specific conditions during solid-phase synthesis, thus augmenting its applicability. This characteristic formulation, thus, serves as a fundamental component in the preparation of specialized peptides. Group: Pharmaceutical. CAS No. 333973-51-6. Pack Sizes: 5 g. Product ID: BAT-003698. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH is a yellowish medical intermediate in the synthesis of Tirzepatide. Tirzepatide is a dual GIP and GLP-1 receptor agonist and a drug candidate for the treatment of type 2 diabetes. Group: Pharmaceutical. CAS No. 2460751-66-8. Pack Sizes: 1 g. Product ID: B1370-449764. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Glatiramer acetate
Glatiramer acetate is an immunomodulator drug currently used to treat multiple sclerosis. It is a random polymer of four amino acids found in myelin basic protein, namely L-glutamic acid, L-lysine, L-alanine, and L-tyrosine. Uses:
multiple sclerosis (ms) is a chronic autoimmune illness that affects the central nervous system. glatiramer acetate is one medicine used to treat ms. glatiramer acetate is primarily used to treat multiple sclerosis (ms), but because of its immunomodulatory qualities and capacity to control inflammatory reactions, scientists have also looked at the possibility of using it in the drug discovery p. Group: Pharmaceutical. CAS No. 147245-92-9. Pack Sizes: 50 mg. Product ID: BAT-014243. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Gly-His-Lys
Gly-His-Lys is a tripeptide that can form a complex with copper ions. It is used for hair growth and skin care in cosmetics. It is a liver cell growth factor and stimulates hepatic erythropoietic factor production. It plays an important role in the care process of skin natural aging, such as cell proliferation, inflammation, angiogenesis, pigment formation and protein synthesis and regulation. Peptides are used in cosmetics to promote collagen production, anti-free radical oxidation, anti-inflammatory repair, anti-edema, whitening, breast enhancement and weight loss. It plays an important role in the care process of skin natural aging, such as cell proliferation, inflammation, angiogenesis, pigment formation and protein synthesis and regulation. Peptides are used in cosmetics to promote collagen production, anti-free radical oxidation, anti-inflammatory repair, anti-edema, whitening, breast enhancement and weight loss. Group: Pharmaceutical. CAS No. 49557-75-7. Pack Sizes: 5 g. Product ID: BAT-010755. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
GSK525762
GSK525762A, also known as I-BET-762 and GSK525762, is a small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins with potential antineoplastic activity. Upon administration, the BET inhibitor GSK525762 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth. Characterized by a tandem repeat of bromodomain at the N-terminus, BET proteins, comprising of BRD2, BRD3, BRD4 and BRDT, are transcriptional regulators that play an important role during development and cellular growth. Group: Pharmaceutical. CAS No. 1260907-17-2. Pack Sizes: 25 mg. Product ID: B2693-457801. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen lysine
Ibuprofen lysine is a non-selective COX inhibitor that can be used as an anti-inflammatory drug. Group: Pharmaceutical. CAS No. 57469-77-9. Pack Sizes: 2 g. Product ID: B2693-072008. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Lactosylsphingosine
Lactosylsphingosine, a sphingolipid, is a vital biomarker characterizing diverse lysosomal storage disorders such as Niemann-Pick disease and Gaucher disease due to its accumulation within the tissues and blood of affected people. Detection through blood examination or imaging studies makes identification possible. Therapy options include substrate reduction and enzyme replacement therapy. Furthermore, tracking variations in lactosylsphingosine may be employed to monitor therapy response and trace disease advancement, imparting substantial clinical value in disease management. Group: Pharmaceutical. CAS No. 109785-20-8. Pack Sizes: 1 mg. Product ID: B2705-003271. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
L-Lysine-diethylamide dihydrochloride
L-Lysine-diethylamide dihydrochloride. Group: Pharmaceutical. CAS No. 266356-00-7. Pack Sizes: 100 mg. Product ID: BAT-014379. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Lys05
Lys05, a water-soluble salt of Lys01, is a selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively, resulting in sustained inhibition of autophagy and tumor growth. Group: Pharmaceutical. CAS No. 1391426-24-6. Pack Sizes: 100 mg. Product ID: B0084-007729. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Lysipressin
Lysipressin Acetate is a lysine vasopressin, which retains water in the body and constricts blood vessels. Group: Pharmaceutical. CAS No. 50-57-7. Pack Sizes: 50 mg. Product ID: BAT-006130. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
MAK683
MAK683 is an inhibitor of embryonic ectoderm development protein (EED) with potential antineoplastic activity. MAK683 binds to the domain of EED that interacts with trimethylated lysine 27 on histone 3 (H3K27me3), leading to a conformational change in the EED H3K27me3-binding pocket and preventing the interaction of EED with the histone methyltransferase enhancer zeste homolog 2 (EZH2). MAK683 is undergoing phase II clinical trials for the identification of antitumor activity. Group: Pharmaceutical. CAS No. 1951408-58-4. Pack Sizes: 5 mg. Product ID: B0084-008118. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
ML SA1
ML SA1 is an activator of TRPML channels. It can induce TRPML-mediated Ca2+ release from lysosomes and reduce cholesterol accumulation in Niemann-Pick type C macrophages. Group: Pharmaceutical. CAS No. 332382-54-4. Pack Sizes: 1 g. Product ID: B2693-169420. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
ML-SI3
ML-SI3 is an antagonist of the TRPML family of calcium channels. ML-SI3 can prevent lysosomal calcium efflux and has been reported to block downstream TRPML1-mediated induction of autophagy. Group: Pharmaceutical. CAS No. 891016-02-7. Pack Sizes: 100 mg. Product ID: B1370-330907. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
MS023
MS023 is a Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. MS023 displayed high potency for type I PRMTs including PRMT1, -3, -4, -6, and -8 but was completely inactive against type II and type III PRMTs, protein lysine methyltransferases and DNA methyltransferases. Group: Pharmaceutical. CAS No. 1831110-54-3. Pack Sizes: 300 mg. Product ID: B0084-470903. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Acetyl-L-seryl-D-α-aspartyl-L-lysyl-L-proline
N-Acetyl-L-seryl-D-α-aspartyl-L-lysyl-L-proline is a natural and specific substrate for the N-terminal site of ACE. Uses: Growth inhibitors. Group: Pharmaceutical. CAS No. 127103-11-1. Pack Sizes: 10 mg. Product ID: BAT-006137. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nα-Fmoc-Nε-2,4-dinitrophenyl-L-lysine
Nα-Fmoc-Nε-2,4-dinitrophenyl-L-lysine. Group: Pharmaceutical. CAS No. 148083-64-1. Pack Sizes: 5 g. Product ID: BAT-005680. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nα-Fmoc-Nε-azide-L-Lysine
The side chain azido (N3) group is stable in trifluoroacetic acid or piperidine. It can be readily converted to amine and to synthesize side chain modified peptides and proteins by Solid Phase Peptide Synthesis (SPPS) methodology. Group: Pharmaceutical. CAS No. 159610-89-6. Pack Sizes: 10 g. Product ID: BAT-007737. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Reagent used for : Suzuki-Miyaura cross-coupling using palladium phosphine catalyst ; Palladium-catalyzed ligand-controlled regioselective Suzuki coupling ; Palladium-catalyzed Suzuki-Miyaura coupling ; Suzuki coupling followed by iodolactonization reaction ; Wrenchnolol derivative optimized for gene activation in cells Reagent used in Preparation of several enzymatic inhibitors and receptor ligands; Orally active anaplastic lymphoma kinase inhibitors ; Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes ; 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands ; Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder ; Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists. Group: Pharmaceutical. CAS No. 286961-14-6. Pack Sizes: 100 g. Product ID: BB019917. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt
N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Group: Pharmaceutical. CAS No. 88793-79-7. Pack Sizes: 50 mg. Product ID: BAT-010163. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
ORY-1001 dihydrochloride
ORY-1001 is a lysine specific demethylase 1 inhibitor under the development of Oryzon with IC50 value < 20nM. It selectively inhibits related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B> 100uM, SMOX 7uM). ORY-1001 can induce apoptosis in THP-1 and inhibit proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). In THP-1 (MLL-AF9) cells, ORY-1001 results in a time-dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers. Group: Pharmaceutical. CAS No. 1431326-61-2. Pack Sizes: 50 mg. Product ID: B0084-470857. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Palifosfamide
Palifosfamide is a synthetic mustard compound with potential antineoplastic activity. An active metabolite of ifosfamide covalently linked to the amino acid lysine for stability, palifosfamide irreversibly alkylates and cross-links DNA through GC base pairs, resulting in irreparable 7-atom inter-strand cross-links; inhibition of DNA replication and cell death follow. Unlike ifosfamide, this agent is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. In addition, because palifosfamide does not require activation by aldehyde dehydrogenase, it may overcome the tumor resistance seen with ifosfamide. Group: Pharmaceutical. CAS No. 31645-39-3. Pack Sizes: 10 mg. Product ID: B0084-090037. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Palmitoyl Tripeptide-38
Palmitoyl tripeptide-38 is a dioxidized lipid peptide composed of three amino acids. The peptide was inspired by a tripeptide that occurs naturally in collagen VI and laminin. It rebuilds the skin from the inside, and soothes wrinkled and smooth skin, especially for forehead lines, crow's feet, headlines, and necklines. It is a palmitoylated synthetic peptide containing lysine and methionine used in skin cosmetics. Group: Pharmaceutical. CAS No. 1447824-23-8. Pack Sizes: 1 g. Product ID: BAT-010794. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Steviol
Steviol is a diterpenoiic carboxylic alcohol and is isolated from the herbs of Stevia rebaudiana. It is the aglycon derivative of natural sweetener steviol glycosides and is found to be highly mutagenic compared to Stevioside. It inhibits the proliferation of the gastrointestinal cancer cells and the human osteosarcoma U2OS cell line in a dose- and time-dependent manner. It also inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4. It increases CYP3A29 expression and enhances pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity. It can be used to treat polycystic kidney disease. It can promote proteasome and lysosome-mediated AQP2 degradation and slow cyst growth by reducing AQP2 transcription. Group: Pharmaceutical. CAS No. 471-80-7. Pack Sizes: 20 mg. Product ID: NP1541. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Tetradecyl phosphonate
Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors with IC50 values of 10 μM, 5.5 μM, and 3.1 μM for inhibition of LPA-induced calcium mobilization, respectively. Group: Pharmaceutical. CAS No. 4671-75-4. Pack Sizes: 100 g. Product ID: B1370-189242. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Thiamet G
Thiamet G is a potent and selective O-GlcNAcase (OGA) inhibitor with Ki of 21 nM, while exhibiting 37000-fold selectivity over human lysosomal-hexosaminidase. Inhibition of OGA by Thiamet G reduced tau pathology in the brain and total tau in the CSF of rTg4510 mice. Group: Pharmaceutical. CAS No. 1009816-48-1. Pack Sizes: 100 mg. Product ID: B0084-264097. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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