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| Product | Description | |
|---|---|---|
| 2,2-Diethylhexanoic acid | 2,2-Diethylhexanoic acid, an important member of the angiotensin receptor blockers (ARBs), is a potent medication for ameliorating chronic heart failure and hypertension. Primarily known for its vasorelaxant properties, it works efficiently by reducing peripheral vascular resistance and regulating blood pressure. Remarkably, this drug has also shown promise in treating a range of tumors, such as breast and ovarian cancers with its unique mechanism of action. The multifaceted nature of 2,2-Diethylhexanoic acid makes it a promising therapeutic option in various clinical settings. Group: Pharmaceutical. CAS No. 4528-37-4. Pack Sizes: 5 g. Product ID: B0001-284792. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 2-Amino-2'-fluorobenzophenone | An intermediate in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Group: Pharmaceutical. CAS No. 1581-13-1. Pack Sizes: 1 g. Product ID: B2694-010195. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (2R,4S)-4-Amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride | An impurity of Sacubitril, a neprilysin inhibitor that is used in combination with valsartan to treat high blood pressure. Group: Pharmaceutical. CAS No. 1038924-71-8. Pack Sizes: 100 mg. Product ID: B2694-013668. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3,4-Diaminobutanoic acid dihydrochloride | 3,4-Diaminobutanoic acid dihydrochloride, a chemical entity employed in biomedicine, has been found to exhibit promise in the management of select neurological conditions. Furthermore, it has been identified to have potential utility in the therapeutic addressing of several inherited metabolic ailments characterized by augmented homocysteine concentrations in the bloodstream, including but not restricted to, homocystinuria. Moreover, its synthetic applications extend beyond the medical arena and encompass its involvement in the assembly of certain antibiotics and its role as a reagent in chemical synthesis. Group: Pharmaceutical. CAS No. 109754-82-7. Pack Sizes: 1 g. Product ID: B2699-346654. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3-O-Acetyl-16α-hydroxytrametenolic acid | 3-O-Acetyl-16α-hydroxytrametenolic acid is a triterpene isolated from the sclerotium of Poria cocos(Schw.)Wolf. It has the inhibitory effect on AAPH-induced hemolysis of red blood cells and 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. Group: Pharmaceutical. CAS No. 168293-13-8. Pack Sizes: 5 mg. Product ID: B0005-053911. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione | The esteemed 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a highly efficacious agent utilized in the management of type 2 diabetes mellitus. By enhancing insulin secretion and suppressing hepatic glucose output, it diligently lowers blood glucose concentrations, thereby promoting normoglycemia. Its demonstrated efficacy and mechanism of action render it an alluring therapeutic option for those with the aforementioned condition. Group: Pharmaceutical. CAS No. 51244-45-2. Pack Sizes: 50 mg. Product ID: B0001-284765. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, a chemical compound with potential therapeutic applications in diabetes and related metabolic disorders, exhibits insulin sensitizing properties that are aimed at lowering high-blood glucose levels and enhancing insulin sensitivity. Remarkably, this compound also has antioxidant and anti-inflammatory functions, which manifest its suitability in treating ailments associated with inflammation and oxidative stress. Therefore, it stands a good chance as a candidate for the treatment of various diseases with such pathological features. Group: Pharmaceutical. CAS No. 6325-94-6. Pack Sizes: 50 mg. Product ID: B0001-284762. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4'-(azidomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Group: Pharmaceutical. CAS No. 152708-24-2. Pack Sizes: 25 mg. Product ID: B2694-376321. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Chloro Hydrochlorothiazide | 5-Chloro Hydrochlorothiazide is a hydrochlorothiazide derivative. Hydrochlorothiazide is a diuretic medication commonly used to treat high blood pressure. Group: Pharmaceutical. CAS No. 5233-42-1. Pack Sizes: 10 mg. Product ID: B2694-259805. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide | Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide is an analog of product H-4876 with small chemical modifications which enhance its stability against proteolytic degradation. It is a β-sheet breaker peptide that crosses the blood-brain barrier faster than most known proteins and peptides selectively absorbed by the brain, so it is assumed that the peptide is specifically transported to the brain. Group: Pharmaceutical. CAS No. 339990-02-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015329. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Anacetrapib | Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Group: Pharmaceutical. CAS No. 875446-37-0. Pack Sizes: 1 g. Product ID: B0084-181147. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Anagrelide Impurities | Anagrelide Impurities are critical in the pharmaceutical development of Anagrelide, a drug used to treat essential thrombocythemia by reducing high platelet counts. Studying these impurities enhances drug safety and efficacy profiles, leading to improved therapeutic outcomes in managing blood disorders associated with increased platelet production. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Argipressin Acetate | Argipressin Acetate is an antidiuretic hormone secreted from the posterior pituitary. Argipressin acts via V1A receptors in blood vessels, causing vasoconstriction, and via V2 receptors in the renal tubules, causing anti-diuresis. Group: Pharmaceutical. CAS No. 129979-57-3. Pack Sizes: 5 mg. Product ID: BAT-006129. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Atipamezole | Atipamezole, a 4-substituted imidazole derivative, is an alpha2-adrenoceptor blocker which could be used for animals to recover from the anesthesia by lowering blood pressure and increasing heart rate and breathing rate. Uses: Atipamezole is an alpha2-adrenoceptor blocker which could be used for animals to recover from the anesthesia by lowering blood pressure and increasing heart rate and breathing rate. Group: Pharmaceutical. CAS No. 104054-27-5. Pack Sizes: 100 mg. Product ID: B0084-081151. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Atipamezole Hydrochloride | The hydrochloride salt form of atipamezole that is an alpha2-adrenoceptor blocker which could be used for animals to recover from the anesthesia by lowering blood pressure and increasing heart rate and breathing rate. Uses: The hydrochloride salt form of atipamezole that is an alpha2-adrenoceptor blocker which could be used for animals to recover from the anesthesia by lowering blood pressure and increasing heart rate and breathing rate. Group: Pharmaceutical. CAS No. 104075-48-1. Pack Sizes: 100 mg. Product ID: B2693-081153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Benidipine hydrochloride | Benidipine hydrochloride is the hydrochloride salt form of Benidipine, which is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). Group: Pharmaceutical. CAS No. 91599-74-5. Pack Sizes: 500 mg. Product ID: B2693-079515. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Betahistine | Betahistine is a H1 receptor agonist, which serves as a vasodilator. It is used in Meniere disease and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. It is an antivertigo drug first used for treating vertigo. It is also commonly used for patients with balance disorders. It is believed to act by reducing the asymmetrical functioning of sensory vestibular organs as well as by increasing vestibulocochlear blood flow. It also acts as a histamine H3-receptor antagonist which causes an increased output of histamine from histaminergic nerve endings which can further increase the direct H1-agonist activity. It has been listed. Uses: Betahistine is used in meniere disease and in vascular headaches. it is an antivertigo drug first used for treating vertigo. it is also commonly used for patients with balance disorders. Group: Pharmaceutical. CAS No. 5638-76-6. Pack Sizes: 2 g. Product ID: B0084-329466. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BIS(1-BUTYLPENTYL) DECANE-1,10-DIYL DIGLUTARATE | Abbreviated as Sec or U, in older publications also as Se-Cys, as a building block of selenoproteins, this 21st proteinogenic amino acid exists naturally in three domains of life, but not in every lineage. Uses: Used for the characterization of total sodium concentration in human blood plasma; also used for the preparation of nitrite-selective membrane electrode, used for the potentiometric determination of nad(p)h coenzymes. Group: Pharmaceutical. CAS No. 101342-76-1. Pack Sizes: 1 g. Product ID: B0001-236189. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BKT140 | BKT140 is a CXCR4 inhibitor with antineoplastic activity. Studies demonstrated that BKT140 showed a robust mobilization of white blood cells (WBC) and hematopoietic stem cells (HSC). Group: Pharmaceutical. CAS No. 664334-36-5. Pack Sizes: 5 mg. Product ID: BAT-006144. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bumetanide Impurities | Bumetanide Impurities, encompassing minor byproducts present during the synthesis of Bumetanide, are crucial in ensuring the purity and efficacy of the diuretic drug Bumetanide, which is primarily used to treat conditions like congestive heart failure, kidney disorders, and liver diseases by reducing fluid retention and lowering blood pressure. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Carmustine | Carmustine is antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. It is used in the treatment of brain tumors, multiple myeloma and some lymphomas. Group: Pharmaceutical. CAS No. 154-93-8. Pack Sizes: 5 g. Product ID: B2693-465289. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ceftriaxone Impurities | Ceftriaxone Impurities hold significant importance within pharmaceutical quality control, specifically related to the cephalosporin antibiotic ceftriaxone. By ensuring drug purity and potency, these impurities guarantee therapeutic effectiveness against bacterial pathogens, including pneumonia, bloodstream infections, and meningitis, while maintaining rigorous regulatory compliance in pharmaceutical production. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chlorogenic acid | Chlorogenic acid is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds. Chlorogenic acid exhibits an anti-inflammatory effect, and reduce blood pressure. Chlorogenic acid has a wide range of biological activities. Modern scientific research on the biological activity of chlorogenic acid has penetrated into many fields such as food, health care, medicine and daily chemical industry. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 327-97-9. Pack Sizes: 100 g. Product ID: NP4264. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chloropyramine Impurity 1 HCl | Tripelennamine hydrochloride, the hydrochloride salt form of tripelennamine, is a blood-brain barrier penetrant and orally active H1 receptor antagonist. Tripelennamine, also known as Pyribenzamine, exhibits antipruritic and first-generation antihistamine properties. Uses: Anti-allergic agents. Group: Pharmaceutical. CAS No. 154-69-8. Pack Sizes: 5 g. Product ID: B0084-363287. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cilazapril Impurities | Cilazapril Impurities are crucial for ensuring the quality and efficacy of the antihypertensive drug Cilazapril, an ACE inhibitor used to treat high blood pressure and heart failure. Studying these impurities aids in improving drug safety profiles and in optimizing pharmaceutical formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Clevidipine Impurity 6 | Clevidipine Impurity 6 is an impurity of clevidipine, a medication used to treat high blood pressure. Group: Pharmaceutical. CAS No. 138279-32-0. Pack Sizes: 100 mg. Product ID: B2694-469136. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Colchicine | Colchicine, a toxic plant-derived alkaloid extracted from plants of the genus Colchicum, inhibits microtubule polymerization (IC50 = 3.2 μM). It inhibits the growth of MCF-7 human breast carcinoma cells and has anti-inflammatory activity. Colchicine can lower body temperature, inhibit the respiratory center, enhance the effect of sympathomimetic drugs, constrict blood vessels, and raise blood pressure. Group: Pharmaceutical. CAS No. 64-86-8. Pack Sizes: 1 g. Product ID: BBF-04529. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Colesevelam hydrochloride | Colesevelam is a bile acid sequestrant that helps reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia, and also improve blood glucose balance in adults with type 2 diabetes mellitus. Group: Pharmaceutical. CAS No. 182815-44-7. Pack Sizes: 500 mg. Product ID: B0046-086232. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Curcumin | Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). Curcumin is a natural phenolic antioxidant extracted from the rhizome of turmeric, curcuma, mustard, curry, turmeric and so on. It is a rare pigment with diketone in the plant kingdom. It is a commonly used seasoning and food coloring and is non-toxic. It has the pharmacological effects of making the uterus produce paroxysmal contractions, reducing blood cholesterol, anti-gallbladder, anti-infection, antiviral, antibacterial, antioxidant (stronger than α-tocopherol), anticoagulation, lowering blood lipids and anti-atherosclerosis. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 458-37-7. Pack Sizes: 1 kg. Product ID: NP5248. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cyanocobalamin Impurity H | Cyano-8-epicobalamin is a Vitamin B12 derivative, which is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Group: Pharmaceutical. CAS No. 41325-63-7. Pack Sizes: 5 mg. Product ID: B2694-469495. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cynaropikrin | Cynaropikrin, a polyphenolic compound, is a sesquiterpene lactone in C. scolymus. Cynaropikrin is the bitter principle in artichoke and is, therefore, an important compound in the chemical profiling of the plant. Cynara scolymus L. (Asteraceae), commonly found in southern Europe and the USA, is cultivated as a vegetable and medicinal plant artichoke leaves are traditionally used for treatment of bile and liver diseases. Pharmacological studies have shown that extracts of the plant significantly increase choleresis (C. scolymus is used for treatment of dyspeptic syndrome) and reduce blood cholesterol, mainly because of inhibition of hepatocellular de novo cholesterol biosynthesis. Group: Pharmaceutical. CAS No. 35730-78-0. Pack Sizes: 10 mg. Product ID: B0005-479861. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CZ415 | CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM; 2. inhibition of Akt (mTORC2 substrate) phosphorylation in HEK293T: IC50 = 14.8 nM; 3. inhibition of IFNγ release in stimulated human whole blood: IC50 = 226 nM. Group: Pharmaceutical. CAS No. 1429639-50-8. Pack Sizes: 5 mg. Product ID: B0084-474821. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dapiprazole Hydrochloride | Dapiprazole Hydrochloride is a salt form of Dapiprazole, an alpha-1-adrenergic antagonist. Dapiprazole inhibits alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris, resulting in vasodilatation. Group: Pharmaceutical. CAS No. 72822-13-0. Pack Sizes: 250 mg. Product ID: B0084-013400. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dendrobine | Dendrobine, that can be found in the herb of Dendrobium nobile Lindl, produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. Dendrobine on the electrical activity and on amino acid-induced depolarizations of primary afferent terminals were tested on the frog isolated spinal cord. Uses: Analgesic/antipyretic. Group: Pharmaceutical. CAS No. 2115-91-5. Pack Sizes: 20 mg. Product ID: NP0819. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Des(2-methylbutyryl) Lovastatin Hydroxy Acid Sodium Salt | An impurity of Lovastatin. Lovastatin is an HMG CoA reductase inhibitor used to treat high blood cholesterol. Group: Pharmaceutical. CAS No. 132294-94-1. Pack Sizes: 10 mg. Product ID: B2694-255494. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diltiazem-[d4] Hydrochloride | Diltiazem-[d4] Hydrochloride is a deuterium labelled form of Diltiazem. Diltiazem is a calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. Group: Pharmaceutical. CAS No. 1217769-52-2. Pack Sizes: 1 mg. Product ID: BLP-006062. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dimethyl-l-arginine | Dimethyl-l-arginine is naturally found in blood plasma. It is produced from the continual protein modification processes in the cytoplasm of all human cells. Uses: Enzyme inhibitors. Group: Pharmaceutical. CAS No. 30315-93-6. Pack Sizes: 250 mg. Product ID: B0350-054018. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Docosahexaenoic acid | Docosahexaenoic acid (DHA) is an omega-3 fatty acid found in fish oil and a major component of excitable membranes of the retina and brain. It decreases the level of blood triglycerides and reduces the risk of cardiovascular disorders. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 6217-54-5. Pack Sizes: 1 g. Product ID: BBF-05818. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dodecyl 2-(N,N-dimethylamino)propionate hydrochloride | Dodecyl 2-(N,N-dimethylamino)propionate hydrochloride, a quaternary ammonium compound, finds extensive use as a phase transfer catalyst to create novel drugs and chemical substances. It also serves as a surfactant in biomedical experiments that enhances drug solubility and effectiveness. Its exceptional attribute of crossing the blood-brain barrier suggests future potential in neurological and psychiatric therapies. Group: Pharmaceutical. CAS No. 259685-49-9. Pack Sizes: 250 mg. Product ID: B0001-306554. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Donepezil | Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Group: Pharmaceutical. CAS No. 120014-06-4. Pack Sizes: 50 g. Product ID: B2692-082304. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Endothelin-3, human, mouse, rabbit, rat | Endothelin 3 is a ligand of the endothelin (ET) receptors and a potent vasoconstrictor. Endothelin 3 increases blood pressure in spontaneously hypertensive and normotensive rats, and promotes migration and adhesion of enteric neural crest cells (ENCCs) to the embryonic gut in mice via interaction with ETB. Uses: Vasoconstrictor. Group: Pharmaceutical. CAS No. 117399-93-6. Pack Sizes: 1 mg. Product ID: BAT-006178. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enoxaparin sodium | Enoxaparin sodium is an anticoagulant medication used for the prevention of blood clots such as deep vein thrombosis (DVT), and also for the treatment of blood vessel complications in patients with angina and heart attack. Group: Pharmaceutical. CAS No. 679809-58-6. Pack Sizes: 1 g. Product ID: B0046-068182. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Epigallocatechin | (-)-Epigallocatechin (EGC) is a natural flavonoid isolated from herbs of Berchemia kulingensis Schneid, and it has prominent antiplatelet activity and blood anticoagulation in a dose-dependent manner. (-)-Epigallocatechin is a natural compound, it can also be used in cosmetics material. Group: Pharmaceutical. CAS No. 970-74-1. Pack Sizes: 250 mg. Product ID: NP1901. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eplerenone | Eplerenone is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure. Group: Pharmaceutical. CAS No. 107724-20-9. Pack Sizes: 20 g. Product ID: NP3116. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Etravirine | Etravirine (ETR, brand name Intelence, formerly known as TMC125) is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Etravirine works by reducing the amount of HIV and increasing the number of CD4 or T cells in the blood. Unlike the currently available agents in the class, resistance to other NNRTIs does not seem to confer resistance to etravirine. Uses: Reverse transcriptase inhibitors. Group: Pharmaceutical. CAS No. 269055-15-4. Pack Sizes: 50 mg. Product ID: B0084-064674. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Phenoxy Glucuronide-[d4] | Ezetimibe Phenoxy Glucuronide-[d4] is the labelled analogue of Ezetimibe Phenoxy Glucuronide, which is a metabolite of Ezetimibe. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 1426174-41-5. Pack Sizes: 10 mg. Product ID: BLP-005427. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Felodipine | Felodipine is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM. It can lower blood pressure by reducing peripheral vascular resistance via a highly selective effect on smooth muscle in arteriolar resistance vessels. Group: Pharmaceutical. CAS No. 72509-76-3. Pack Sizes: 5 g. Product ID: NP3226. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fevipiprant | Fevipipran is a reversible competitive CRTh2 antagonist with IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood. Now it is in Phase III clinical trials for the treatment of asthma. Uses: Allergic asthma; atopic dermatitis. Group: Pharmaceutical. CAS No. 872365-14-5. Pack Sizes: 50 mg. Product ID: B0084-474118. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Genistein | Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. Genistein is developed to be an antitumor agent. Genistein has antioxidant effect, it can be used in cosmetics material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation and antibacterial effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. Uses: Antitumor agent. Group: Pharmaceutical. CAS No. 446-72-0. Pack Sizes: 5 g. Product ID: BBF-01840. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glipizide | Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. Glipizide is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes. Uses: Hypoglycemic agents. Group: Pharmaceutical. CAS No. 29094-61-9. Pack Sizes: 50 g. Product ID: B2692-089502. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Guanfacine hydrochloride | Guanfacine, a selective agonist of α2A receptor, is a sympatholytic drug to treat attention deficit hyperactivity disorder (ADHD) and hypertension. It lowers both systolic and diastolic blood pressure. Group: Pharmaceutical. CAS No. 29110-48-3. Pack Sizes: 500 mg. Product ID: B0084-065259. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hederagenin - 3-O-β-D- Galactosyl( 1?3)-β-D-glucosyl( 1?3)-α-L-rhamnosyl(1?2)-α-L-arabinoside | Hederagenin - 3-O-β-D- Galactosyl( 1→3)-β-D-glucosyl( 1→3)-α-L-rhamnosyl(1→2)-α-L-arabinoside is a triterpenoids isolated from pulsatilla chinensis BungeRegel. Pulsatilla chinensis (Bunge) Regel is a botanical with a long history of medical use in China, which exhibits "blood-cooling" and detoxification activities. The roots of P. chinensis have been widely used in the traditional Chinese medicine for adjunctive treatment of intestinal amebiasis, malaria, vaginal trichomoniasis, bacterial infections and malignant tumor. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B0005-482208. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Honokiol | Honokiol is a polyphenol found in the genus Magnolia. Honokiol acts as an Akt inhibitor and also inhibits NF-κB, displaying anti-inflammatory, antiangiogenic and antitumor properties. It results in inhibition of bone metastatic growth of human prostate cancer cells. Honokiol has obvious antioxidant and anti-aging effects, thus can be used in cosmetic material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. It has the activity of antibacterial, anti-inflammatory, antioxidant, oil control, acne, promoting healing, and can be widely used in anti-acne, deodorization, acne and other products. Uses: Anti-inflammatory and anti-cancer agent. Group: Pharmaceutical. CAS No. 35354-74-6. Pack Sizes: 50 g. Product ID: BBF-03868. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hydrochlorothiazide EP Impurity C | An impurity of Hydrochlorothiazide, a diuretic medication used for the treatment of high blood pressure. Group: Pharmaceutical. CAS No. 402824-96-8. Pack Sizes: 5 mg. Product ID: B2694-258731. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Irbesartan Related Compound A | A metabolite of Irbesartan, an angiotensin II receptor blocker used for the treatment of high blood pressure, heart failure, and diabetic kidney disease. Group: Pharmaceutical. CAS No. 748812-53-5. Pack Sizes: 1 g. Product ID: B1370-302026. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isocorynoxeine | Isocorynoxeine, one of the major alkaloids from Uncaria Hook, shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. Group: Pharmaceutical. CAS No. 51014-29-0. Pack Sizes: 10 mg. Product ID: NP0559. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isopropyl 4-[4-[N,N-bis(2-hydroxyethyl)amino]phenyl]butyrate | Isopropyl 4-[4-[N,N-bis(2-hydroxyethyl)amino]phenyl]butyrate, a pharmaceutical intermediate, can be utilized in the production of drugs intended for the treatment of cardiovascular disease, such as hypertension. It functions as an angiotensin-converting enzyme (ACE) inhibitor, which reduces the likelihood of heart attack and stroke by regulating blood pressure levels. Consequently, it plays a valuable role in managing these serious medical conditions, thus improving overall health outcomes among patients. Group: Pharmaceutical. CAS No. 94086-78-9. Pack Sizes: 10 mg. Product ID: B2699-045702. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isradipine | Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure. Group: Pharmaceutical. CAS No. 75695-93-1. Pack Sizes: 500 mg. Product ID: B2692-076559. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JNJ-26483327 | JNJ-26483327 is an orally bioavailable, small-molecule, multitargeted reversible tyrosine kinase inhibitor with potential antineoplastic activity. Multitargeted tyrosine kinase inhibitor JNJ-26483327 binds to and inhibits several members of the epidermal growth factor receptor (EGFR) family, including EGFR, HER2 and HER4; Src family kinases (Lyn, Yes, Fyn, Lck and Src); and vascular endothelial growth factor receptor type 3 (VEGFR3). By inhibiting several different signaling molecules that play crucial roles at various stages in tumorigenesis, this agent may inhibit tumor growth, invasion, migration and metastasis. In addition, JNJ-26483327 crosses the blood-brain barrier (BBB). Group: Pharmaceutical. CAS No. 807640-87-5. Pack Sizes: 10 mg. Product ID: B0084-462547. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Labetalol-1-carboxylic Acid Methyl Ester | An impurity of Labetalol, a beta blocker used to treat high blood pressure. Group: Pharmaceutical. CAS No. 802620-01-5. Pack Sizes: 100 mg. Product ID: B2694-009631. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Labetalol Impurity A | Labetalol Impurity A is an impurity of Labetalol, a medication used for the treatment of high blood pressure, and also for long term management of angina. Group: Pharmaceutical. CAS No. 1391051-99-2. Pack Sizes: 2 g. Product ID: B1275-473550. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| L-α-Aspartyl-D-phenylalanine methyl ester | L-α-Aspartyl-D-phenylalanine methyl ester, a dipeptide compound, bears promise in the biomedical sector for its potential inhibitory impact on angiotensin converting enzyme (ACE), thus potentially reducing blood pressure levels. It has also shown potential in the treatment of hypertensive, cardiac failure, and other cardiovascular conditions. The study of its properties continues to generate interest and attention from academia and the scientific community. Group: Pharmaceutical. CAS No. 22839-65-2. Pack Sizes: 50 mg. Product ID: B2699-116576. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lanreotide | Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanine, resulting in DNA crosslinking, strand breaks, chromosomal aberrations, and disruption of DNA synthesis. Intracellular metabolism of this agent also releases methyl isocyanate which inhibits 06-alkyl-guanine transferase, an enzyme involved with DNA repair. Group: Pharmaceutical. CAS No. 108736-35-2. Pack Sizes: 25 mg. Product ID: BAT-010202. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lesinurad Impurity 16 | An intermediate of Lesinurad, a urate transporter inhibitor used for the treatment of high blood uric acid levels associated with gout. Group: Pharmaceutical. CAS No. 878671-99-9. Pack Sizes: 1 g. Product ID: B2694-473688. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Linarin | Linarin is a flavone glycoside isolated from the herb of Uncaria sinensis (Oliv.) Havil. It is also an impurity of Diosmin, a medication used for the treatment of various disorders of blood vessels. Group: Pharmaceutical. CAS No. 480-36-4. Pack Sizes: 100 mg. Product ID: NP1809. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lisinopril Impurity D | An impurity of ACE inhibitor Lisinopril, which is indicated for the treatment of high blood pressure and heart failure. Group: Pharmaceutical. CAS No. 219677-82-4. Pack Sizes: 100 mg. Product ID: B2694-102578. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lisinopril Impurity F | Lisinopril Impurity F is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Group: Pharmaceutical. CAS No. 1132650-67-9. Pack Sizes: 10 mg. Product ID: B2694-262437. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Losartan Impurities | Losartan Impurities are critical reference standards in the biomedical industry, extensively utilized to ensure the purity and efficacy of Losartan, an antihypertensive drug used primarily to manage high blood pressure and renal protection in patients with type 2 diabetes. These impurities are essential for quality control and regulatory compliance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Losartan Impurity E | An impurity of Losartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure. Group: Pharmaceutical. CAS No. 120568-11-8. Pack Sizes: 1 g. Product ID: B2694-162110. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Loureirin A | Loureirin A is a chalcone extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. It is a part of traditional Chinese medicine which helps combat neurodegenerative diseases. It inhibits platelet activation by an impairment of PI3K/Akt signaling. It also could inhibit Akt phosphorylation. It negatively affects agonist-induced platelet aggregation such as ADP, collagen, thrombin and collagen-related peptide (CRP). It promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound by activating Wnt/-catenin pathway. Group: Pharmaceutical. CAS No. 119425-89-7. Pack Sizes: 250 mg. Product ID: NP0980. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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