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| Product | Description | |
|---|---|---|
| Bis(2-chloroethyl) ether | Bis(2-chloroethyl) ether. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 111-44-4. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| N,N'-bis-(2-Chloroethyl)urea | N,N'-bis-(2-Chloroethyl)urea is an indispensable compound in the field of biomedicine manifesting remarkable cytotoxic characteristics. Its application extends to diverse cancer types, encompassing lymphoma, leukemia and solid tumors, owing to its potent chemotherapeutic attributes. Group: Pharmaceutical. Alternative Names: 1,3-bis(2-chloroethyl)urea; 1,3-Bis(2-chloroethyl)urea; 2214-72-4; N,N'-Bis(2-chloroethyl)urea; VBWBRZHAGLZNST-UHFFFAOYSA-N; Urea,N,N'-bis(2-chloroethyl)-. CAS No. 2214-72-4. Pack Sizes: 10 g. Product ID: B1331-063180. Molecular formula: C5H10Cl2N2O. Mole weight: 185.053. Custom synthesis is available. Send your inquiries for more information. |  London |
| Bendamustine Chloro Dimer Impurity | Bendamustine Chloro Dimer Impurity is an impurity of Bendamustine, a chemotherapy medication indicated for the treatment of chronic lymphocytic leukemia, multiple myeloma, and non-Hodgkin's lymphoma. Group: Pharmaceutical. Alternative Names: Bendamustine Dimer Impurity; 5-[bis(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 2-[[2-(3-Carboxypropyl)-1-methyl-1H-benzimidazol-5-yl](2-chloroethyl)amino]ethyl Ester. CAS No. 1228551-91-4. Pack Sizes: 10 mg. Product ID: B2694-467289. Molecular formula: C32H41Cl3N6O4. Mole weight: 680.08. Custom synthesis is available. Send your inquiries for more information. | London |
| Carmustine | Carmustine is antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. It is used in the treatment of brain tumors, multiple myeloma and some lymphomas. Group: Pharmaceutical. Alternative Names: 1,3-Bis(2-chloroethyl)-1-nitrosourea; BCNU; Carmustin. CAS No. 154-93-8. Pack Sizes: 5 g. Product ID: B2693-465289. Molecular formula: C5H9Cl2N3O2. Mole weight: 214.05. Custom synthesis is available. Send your inquiries for more information. | London |
| Chlorambucil | Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. Group: Pharmaceutical. Alternative Names: gamma-(p-bis(2-chloroethyl)aminophenyl)butyric acid. CAS No. 305-03-3. Pack Sizes: 5 g. Product ID: B1370-065622. Molecular formula: C14H19Cl2NO2. Mole weight: 304.21. Custom synthesis is available. Send your inquiries for more information. | London |
| Ifosfamide | Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. Uses: Antineoplastic agents, alkylating. Group: Pharmaceutical. Alternative Names: 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide; 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide; (2-Chloro-ethyl)-[3-(2-chloro-ethyl)-2-oxo-2λ*5*-[1,3,2]oxazaphosphinan-2-yl]-amine; (±)-Ifosfamide; 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; A 4942; Asta Z 4942; Cyfos; Holoxan; Holoxan 1000; Ifex; Ifomide; Ifosfamid; Ifosfomide; Ifosphamide; Iphosphamide; Isoendoxan; Isofosfamide; Isophosphamide; Mitoxana; MJF 9325; Naxamide; NSC 109724; Z 4942. CAS No. 3778-73-2. Pack Sizes: 5 g. Product ID: B2693-114093. Molecular formula: C7H15Cl2N2O2P. Mole weight: 261.09. Custom synthesis is available. Send your inquiries for more information. | London |
| Palifosfamide | Palifosfamide is a synthetic mustard compound with potential antineoplastic activity. An active metabolite of ifosfamide covalently linked to the amino acid lysine for stability, palifosfamide irreversibly alkylates and cross-links DNA through GC base pairs, resulting in irreparable 7-atom inter-strand cross-links; inhibition of DNA replication and cell death follow. Unlike ifosfamide, this agent is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. In addition, because palifosfamide does not require activation by aldehyde dehydrogenase, it may overcome the tumor resistance seen with ifosfamide. Group: Pharmaceutical. Alternative Names: Isophosphamide mustard; Isophosphoramide mustard; IPAM; bis(2-chloroethylamino)phosphinic acid. CAS No. 31645-39-3. Pack Sizes: 10 mg. Product ID: B0084-090037. Molecular formula: C4H11Cl2N2O2P. Mole weight: 221.018. Custom synthesis is available. Send your inquiries for more information. | London |
| PX-478 dihydrochloride | PX-478 is an HIF-1alpha inhibitor and an orally active small molecule with potential antineoplastic activity. Although its mechanism of action has yet to be fully elucidated, HIF1-alpha inhibitor PX-478 appears to inhibit hypoxia-inducible factor 1-alpha (HIF1A) expression, which may result in decreased expression of HIF1A downstream target genes important to tumor growth and survival, a reduction in tumor cell proliferation, and the induction of tumor cell apoptosis. The inhibitory effect of this agent is independent of the tumor suppressor genes VHL and p53 and may be related to derangements in glucose uptake and metabolism due to inhibition of glucose transporter-1 (Glut-1). PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity. It is rapidly absorbed following oral and i.p. administration and gives excellent Cmax and AUC via these routes. Group: Pharmaceutical. Alternative Names: PX-478 2HCl; PX-478 hydrochloride; Melphalan N-Oxide Impurity HCl; Melphalan N-Oxide Impurity hydrochloride; L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoamino]-, dihydrochloride; L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoamino]-, hydrochloride (1:2). CAS No. 685898-44-6. Pack Sizes: 100 mg. Product ID: B2693-459441. Molecula | London |
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