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| Product | Description | |
|---|---|---|
| 1-benzyl-4-ethoxybenzene | 1-benzyl-4-ethoxybenzene is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: Benzene,1-ethoxy-4-(phenylmethyl)-; 1-benzyl-4-ethoxy-benzene. CAS No. 35672-52-7. Pack Sizes: 100 mg. Product ID: B1370-377700. Molecular formula: C15H16O. Mole weight: 212.29. Custom synthesis is available. Send your inquiries for more information. |  London |
| 5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol | An impurity of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Group: Pharmaceutical. Alternative Names: (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol. CAS No. 142217-78-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3098. Molecular formula: C52H49N5O5. Mole weight: 824. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(3,5-Bis((S)-octan-2-yloxy)benzyloxy)isophthalic acid | 5-(3,5-Bis((S)-octan-2-yloxy)benzyloxy)isophthalic acid, a chemical compound employed in drug delivery systems, is gaining significant attention in the pharmaceutical industry due to its potential in effective drug delivery for treating various diseases including cancers and inflammation. Its enormous impact lies in its ability to transport therapeutic agents to targeted human organs for curing or preventing fatal diseases, thus demonstrating its indispensable contribution to the medical sector. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B0001-284817. Molecular formula: C31H44O7. Mole weight: 528.68. Custom synthesis is available. Send your inquiries for more information. | London |
| AC1903 | AC1903 is an inhibitor of transient receptor potential canonical channel 5 (TRPC5; IC50 = 14.7 μM). Group: Pharmaceutical. Alternative Names: 1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine. CAS No. 831234-13-0. Pack Sizes: 1mg;1g;10g. Product ID: 831234-13-0. Molecular formula: C19H17N3O. Mole weight: 303.4. Custom synthesis is available. Send your inquiries for more information. | London |
| BML-284 | BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Group: Pharmaceutical. Alternative Names: BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine. CAS No. 853220-52-7. Pack Sizes: 25 mg. Product ID: B0084-474867. Molecular formula: C19H18N4O3. Mole weight: 350.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Coelenterazine | Coelenterazine is a luciferin that serves as a substrate for luciferases. Coelenterazine can be used for probing superoxide anion and aequorin assays. Coelenterazine is also used to detect Ca2+ concentration in cells that have been transfected with apoaequorin cDNA. Group: Pharmaceutical. Alternative Names: 2-(4-Hydroxybenzyl)-6-(4-hydroxyphenyl)-8-benzyl-3,7-dihydroimidazo(1,2-a)pyrazin-3-one. CAS No. 55779-48-1. Pack Sizes: 100 mg. Product ID: B1370-375048. Molecular formula: C26H21N3O3. Mole weight: 423.46. Custom synthesis is available. Send your inquiries for more information. | London |
| IACS-010759 | IACS-010759 is an orally bioavailable inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targeting complex I of the electron transport chain (NADH ubiquinone oxidoreductase). Study showed that IACS-010759 induced AMPK activation leading to mTOR suppression which resulted in cell growth inhibition in AML cells. Group: Pharmaceutical. Alternative Names: 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole. CAS No. 1570496-34-2. Pack Sizes: 10 mg. Product ID: B2693-291404. Molecular formula: C25H25F3N6O4S. Mole weight: 562.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Obicetrapib | Obicetrapib is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors can increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may help reduce the risk of cardiovascular disease. Group: Pharmaceutical. Alternative Names: 1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl][5-(3-carboxypropoxy)-2-pyrimidinyl]amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-ethyl ester, (2R,4S)-; 1-Ethyl (2R,4S)-4-[[[3,5-bis(trifluoromethyl)phenyl]methyl][5-(3-carboxypropoxy)-2-pyrimidinyl]amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-1(2H)-quinolinecarboxylate; (2R,4S)-4-[[3,5-Bis(trifluoromethyl)benzyl][5-(3-carboxypropoxy)pyrimidin-2-yl]amino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester; AMG-899; AMG 899; AMG899; TA-8995; TA8995; TA 8995; DEZ-001; DEZ 001; DEZ001; Obicetrapib (free base). CAS No. 866399-87-3. Pack Sizes: 25 mg. Product ID: B1370-447410. Molecular formula: C32H31F9N4O5. Mole weight: 722.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Plerixafor Impurity III | Plerixafor Impurity III is an impurity of Plerixafor, an immunostimulant indicated in combination with G-CSF to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with NHL and MM. Group: Pharmaceutical. Alternative Names: 1,11-Bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecane. CAS No. 771464-86-9. Pack Sizes: 5 mg. Product ID: B2694-341919. Molecular formula: C46H84N12. Mole weight: 805.24. Custom synthesis is available. Send your inquiries for more information. | London |
| Ponesimod | Ponesimod is an orally active and selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator that acts as a functional antagonist. It has potential immunomodulating activity. It may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. It is also an experimental drug for the treatment of multiple sclerosis (MS) and psoriasis. It protects against lymphocyte-mediated tissue inflammation. It activated S1P(1)-mediated signal transduction with high potency (EC(50) of 5.7 nM) and selectivity in vitro. It prevented edema formation, inflammatory cell accumulation and cytokine release in the skin of mice with delayed-type hypersensitivity. It also prevented the increase in paw volume and joint inflammation in rats with adjuvant-induced arthritis. It reduces both the amount of circulating peripheral lymphocytes and the infiltration of lymphocytes into target tissues by preventing egress of lymphocytes. It was developed by Actelion. It is in Clinical stage three. Uses: Ponesimod acts as a functional antagonist. it has potential immunomodulating activity. it may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. it is also an experimental drug for the treatment of multiple sclerosis (ms) and psoriasis. Group: Pharmaceutical. Alternative Names: ACT-128800; ACT 128800; ACT128800; Ponvory; (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolylÂ… | London |
| Seliciclib | Seliciclib is an orally bioavailable, small-molecule cyclin-dependent kinase (CDK) inhibitor with potential proapoptotic and antineoplastic activities. Seliciclib primarily inhibits CDK2/E, CDK2/A, CDK7 and CDK9 by competing for their ATP binding sites, leading to a disruption of cell cycle progression. In addition, this agent appears to interfere with CDK-mediated phosphorylation of the carboxy-terminal domain of RNA polymerase II, inhibiting RNA polymerase II-dependent transcription, which may result in the down-regulation of antiapoptotic proteins such as induced myeloid leukemia cell differentiation protein Mcl-1. CDKs, serine/threonine kinases that play an important role in cell cycle regulation, are overexpressed in various malignancies. Mcl-1 belongs to the Bcl-2 family of antiapoptotic proteins and is a protein crucial to the survival of a range of tumor cell types. Group: Pharmaceutical. Alternative Names: R-roscovitine; Roscovitin; Roscovitine; CYC202; CYC202; CYC 202; (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol. CAS No. 186692-46-6. Pack Sizes: 100 mg. Product ID: B1370-086385. Molecular formula: C19H26N6O. Mole weight: 354.44. Custom synthesis is available. Send your inquiries for more information. | London |
| SU 5214 | SU 5214 is a modulator of tyrosine kinase signal transduction. Group: Pharmaceutical. Alternative Names: SU 5214; SU5214; SU-5214; (3Z)-3-o-Anisylideneoxindole; 3-(2-Methoxy-benzylidene)-3H-indol-2-ol; (3Z)-3-[(2-methoxyphenyl)methylidene]-1H-indol-2-one. CAS No. 186611-04-1. Pack Sizes: 50 mg. Product ID: B0084-284848. Molecular formula: C16H13NO2. Mole weight: 251.285. Custom synthesis is available. Send your inquiries for more information. | London |
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