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Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[6-(benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester is a novel biomedical compound. With its unique molecular structure, it exhibits potential as a targeted therapeutic agent for treating various diseases. Group: Pharmaceutical. Alternative Names: Morpholino A subunit; PMO-BzA; [(2S,6R)-6-[6-(Benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl N,N-dimethylphosphoramidochloridate; N6-Bz protected A PMO Monomer. CAS No. 956139-18-7. Pack Sizes: 1 g. Product ID: B2706-339312. Molecular formula: C38H37ClN7O4P. Mole weight: 722.17. Custom synthesis is available. Send your inquiries for more information.
This product is a potent inhibitor of Abl kinases and was developed for the treatment of chronic myeloid leukemia (CML). It works by blocking the activity of the Bcr-Abl fusion protein, which drives the growth of CML cells. Clinical trials have shown promising results, with high rates of complete remission and durable responses in patients with CML who were resistant or intolerant to previous treatments. Group: Pharmaceutical. Alternative Names: PMO-BzC; Morpholino C subunit; Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester; [(2S,6R)-6-[4-(Benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methyl N,N-dimethylphosphoramidochloridate; N4-Bz protected C PMO Monomer. CAS No. 956139-21-2. Pack Sizes: 1 g. Product ID: B2706-339313. Molecular formula: C37H37ClN5O5P. Mole weight: 698.15. Custom synthesis is available. Send your inquiries for more information.
3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite is a modified nucleotide used in the synthesis of Threose Nucleic Acid (TNA) molecules for biomedical research. TNA is a promising alternative to DNA and RNA for gene and drug delivery due to its chemical stability and resistance to nuclease degradation. This specific phosphoramidite derivative incorporates a benzoyl-adenosine moiety, making it ideal for designing TNA-based drugs for the treatment of viral infections, inflammatory diseases, and cancer. Group: Pharmaceutical. Alternative Names: DMTr-TNA A(Bz)-amidite; TNA-A(Bz)-CE-Phosphoramidite; DMTr-TNA A(Bz)-Phosphoramidite; N-Benzoyl-9-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]-9H-purine-6-amine; 1-{2'-O-[(2-Cyanoethoxy)(diisopropyl amino)phosphino]-3'-O-[(4,4'-dimethoxytriphenyl)methyl]-a-L-threofuranosyl}-N6-benzoyladenine; (2R,3R,4S)-2-[6-(Benzoylamino)-9H. CAS No. 325683-93-0. Pack Sizes: 1 g. Product ID: B1370-376747. Molecular formula: C46H50N7O7P. Mole weight: 843.92. Custom synthesis is available. Send your inquiries for more information.
TNA 2'-CE oligonucleotide synthesis necessitates 3'-O-DMT-N6-benzoyl-cytidine, and our TNA 2'-CE phosphoramidite is precisely engineered for just that purpose. Researchers within the biomedicine discipline rely heavily on our product due to their capacity to incorporate TNA monomers as they fabricate artificial nucleic acids for gene-based therapeutics and pharmacological advancement. Group: Pharmaceutical. Alternative Names: Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; DMTr-TNA C(Bz)-amidite; (2R,3R,4S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; TNA-C(Bz)-CE-Phosphoramidite; N-Benzoyl-1-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]cytosine; DMTr-TNA-C(Bz)-Phosphoramidite. CAS No. 325683-96-3. Pack Sizes: 1 g. Product ID: B1370-376748. Molecular formula: C45H50N5O8P. Mole weight: 819.9. Custom synthesis is available. Send your inquiries for more information.
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AC-55541
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist which displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. It activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. It was well absorbed when administered intraperitoneally to rats, reaching micromolar peak plasma concentrations. It was stable to metabolism by liver microsomes and maintained sustained exposure in rats. Uses: Ac-55541 stimulates cell proliferation, phosphatidylinositol hydrolysis, and calcium mobilization. Group: Pharmaceutical. Alternative Names: AC-55541; AC 55541; AC55541. (2E)-2-[1-(3-Bromophenyl)ethylidene]α-(benzoylamino)-3,4-dihydro-4-oxo-1-phthalazineaceticacidhydrazide;AC 55541;alpha-(Benzoylamino)-3,4-dihydro-4-oxo-1-phthalazineacetic acid (2E)-2-[1-(3-bromophenyl)ethylidene]hydrazide;N-[2-[(2E)-2-[1-(3-bromophenyl)ethylidene]hydrazinyl]-2-oxo-1-(4-oxo-3H-phthalazin-1-yl)ethyl]benzamide. CAS No. 916170-19-9. Pack Sizes: 300 mg. Product ID: B0084-271988. Molecular formula: C25H20BrN5O3. Mole weight: 518.36. Custom synthesis is available. Send your inquiries for more information.
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N-Benzoyl-(2R,3S)-3-phenylisoserine
An impurity of Paclitaxel which is a chemotherapy medication. Group: Pharmaceutical. Alternative Names: (2R,3S)-N-Benzoyl-3-phenyl Isoserine; (αR,βS)-β-(Benzoylamino)-α-hydroxybenzenepropanoic Acid; [R-(R*,S*)]-β-(benzoylamino)-α-hydroxybenzenepropanoic Acid; (2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropionic Acid; (2R,3S)-N-Benzoyl-3-phenylisoserine. CAS No. 132201-33-3. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008054. Molecular formula: C16H15NO4. Mole weight: 285.3. Custom synthesis is available. Send your inquiries for more information.
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OSS-128167
OSS-128167 is a selective SIRT6 inhibitor (IC50 = 89 μM). Group: Pharmaceutical. Alternative Names: OSS 128167; OSS128167; SIRT6-IN-1; STK292625; STK 292625; STK-292625; 5-[3-(furan-2-amido)benzamido]-2-hydroxybenzoic acid; 5-{3-[(Furan-2-carbonyl)-amino]-benzoylamino}-2-hydroxy-benzoic acid. CAS No. 887686-02-4. Pack Sizes: 100 mg. Product ID: B1370-055357. Molecular formula: C19H14N2O6. Mole weight: 366.32. Custom synthesis is available. Send your inquiries for more information.
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Paclitaxel EP Impurity E
Paclitaxel EP Impurity E is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Group: Pharmaceutical. Alternative Names: 4,10β-Bis(acetyloxy)-13α-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1,7α-dihydroxy-9-oxo-5β,20-epoxytax-11-en-2α-yl benzoate; 7-epi-Paclitaxel; 7-Epipaclitaxel; 7-Epitaxol; 7-epi-Taxol; Epitaxol; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4α,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-; (2aR,4R,4aS,6R,9S,11S,12S,12bS)-9-(((2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate. CAS No. 105454-04-4. Pack Sizes: 100 mg. Product ID: NP1592. Molecular formula: C47H51NO14. Mole weight: 853.91. Cust
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Paclitaxel EP Impurity G
Paclitaxel EP Impurity G is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Group: Pharmaceutical. Alternative Names: 4-(Acetyloxy)-13α-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-en-2α-yl benzoate; 10-O-Deacetylpaclitaxel; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-; 10-Deacetylpaclitaxel; 10-Deacetyltaxol; 10-Deacetyltaxol A; 10-Desacetylpaclitaxel; 10-Desacetyltaxol; 10-O-Deacetyltaxol; Paclitaxel impurity G; (2aR,4S,4aS,6R,9S,11S,12S,12bS)-12b-Acetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate. CAS No. 78432-77-6. Pack Si
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Paclitaxel EP Impurity H
Paclitaxel EP Impurity H is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Group: Pharmaceutical. Alternative Names: 4-(Acetyloxy)-13α-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1,7α,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-en-2α-yl benzoate; 10-O-Deacetyl-7-epi-paclitaxel; 7-Epi-10-deacetyltaxol; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; 10-Deacetyl-7-epi-paclitaxel; 10-Deacetyl-7-epi-taxol; 10-Deacetyl-7-epipaclitaxel; 10-Deacetyl-7-epitaxol; 10-Desacetyl-7-epipaclitaxel; 7-epi-10-Deacetylpaclitaxel; Ormosin VI; USP Paclitaxel Related Compound B; Paclitaxel USP Related Compound B; Paclitaxel Related Compound B. CAS No. 78454-17-8. Pack Sizes: 25 mg. Product ID: NP1519. Molecular formula: C45H49NO13. Mole weight: 811.88. Custom synthesis is available. Send your inquiries for more information.
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Paclitaxel EP Impurity K
Paclitaxel EP Impurity K is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Group: Pharmaceutical. Alternative Names: 4,10β-bis(acetyloxy)-13α-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1-hydroxy-9-oxo-7β-[(triethylsilyl)oxy]-5β,20-epoxytax-11-en-2α-yl benzoate; 7-O-(Triethylsilanyl)paclitaxel; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-; 7-(Triethylsilyl)taxol; 7-O-(Triethylsilyl)paclitaxel; 7-O-(Triethylsilyl)taxol; 7-Tes-paclitaxel. CAS No. 148930-55-6. Pack Sizes: 10 mg. Product ID: B1370-264237. Molecular formula: C53H65NO14Si. Mole weight: 968.19. Custom synthesis is available. Send your inquiries for more information.
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TMC-58B
Aurantiamide, a natural alkaloid found in the herbs of Walsura yunnanensis, is used as significant anti-inflammatory and antinociceptive. it can serve as the natural compound for inhibiting cysteine proteinases, in particular, cathepsin L (3.4.22.15) and B (3.4.22.1) with IC50 of 12 microM and 49 microM, respectively. It may suppress the growth of malignant gliomas by blocking autophagic flux. Uses: Anti-neuroinflammatory; anti-inflammatory; antinociceptive. Group: Pharmaceutical. Alternative Names: (S)-α-(Benzoylamino)-N-[(S)-1-(hydroxymethyl)-2-phenylethyl]benzenepropanamide. CAS No. 58115-31-4. Pack Sizes: 1 mg. Product ID: NP0417. Molecular formula: C25H26N2O3. Mole weight: 402.5. Custom synthesis is available. Send your inquiries for more information.
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