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Bardoxolone methyl (also known as "RTA 402" and "CDDO-methyl ester") is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. It is the most potent known inducer of the Nrf2 pathway to enter clinical development and works to suppress both oxidative stress and inflammation. Uses: Bardoxolone methyl, also known as rta 402, is a semisynthetic derivative of oleanolic acid that has attracted much attention in the medical community for its potential to treat a variety of chronic diseases, especially chronic kidney disease (ckd). as a member of the antioxidant inflammatory modulator (aim) class of drugs, bardoxolone methyl exerts its therapeutic effects by targeting inflammation. Group: Pharmaceutical. Alternative Names: CDDO Methyl ester; CDDOMe; RTA 402; RTA-402; RTA402; TP-155; TP155; TP 155; 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid methyl ester; bardoxolone methyl; CDDO-Me; methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate; (4aS,6aR,6bS,8aR,12aS,14bS)-Methyl 11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylate. CAS No. 218600-53-4. Pack Sizes: 250 mg. Product ID: BAT-008967. Molecular formula: C32H43NO4. Mole weight: 505.7. Custom synthesis is available. Send your inquiries for more information.
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