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| Product | Description | |
|---|---|---|
| BAR-501 | BAR-501, a UDCA derivative, is a selective GPBAR1 agonist devoid of any FXR agonistic activity. BAR-501 effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1, with a EC50 of 1 μM. Besides, it protects against development of portal hypertension in rodent models of liver injury and endothelial dysfunction. Group: Pharmaceutical. CAS No. 1632118-69-4. Pack Sizes: 10 mg. Product ID: B0084-482211. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Bar-501 Impurities | Bar-501 Impurities hold critical importance within the pharmaceutical realm, particularly in the stringent quality control processes during Bar-501 synthesis—a bile acid derivative employed in liver disease management. Vigilant monitoring of these impurities guarantees drug efficacy and safety, essential for addressing chronic hepatic conditions and advancing therapeutic innovations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (3alpha,5beta,6beta,7alpha)-6-Ethylcholane-3,7,24-triol | An impurity of BAR-501 which is a selective GPBAR1 agonist devoid of any FXR agonistic activity. Group: Pharmaceutical. CAS No. 1632118-70-7. Pack Sizes: 10 mg. Product ID: B1662-482217. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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