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| Product | Description | |
|---|---|---|
| Azoramide | Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones to protect cells against ER stress in multiple systems. It regulates ER folding and secretion capacity without inducing ER stress. It might have the protective effects of enhancing chaperone expression and reducing protein synthesis without inducing cytotoxicity and apoptosis. It showed potent antidiabetic activity in two independent mouse models of obesity by protecting pancreatic β cell function against ER stress and improving insulin sensitivity in vivo. It improves glucose homeostasis in mice with genetic obesity and diet-induced obesity. Group: Pharmaceutical. Alternative Names: N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide. CAS No. 932986-18-0. Pack Sizes: 100 mg. Product ID: B1370-474920. Molecular formula: C15H17ClN2OS. Mole weight: 308.82. Custom synthesis is available. Send your inquiries for more information. |  London |
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