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| Product | Description | |
|---|---|---|
| 1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo(4',5':4,5)benzo(1,2-d)azepine | One of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It is a prescription drug used to treat cigarette addiction. Group: Pharmaceutical. Alternative Names: 5,9-Methanoimidazo(4,5-H)(3)benzazepine, 1,5,6,7,8,9-hexahydro-; 1,?5,?6,?7,?8,?9-Hexahydro-5,?9-methanoimidazo[4,?5-h]?[3]?benzazepine. CAS No. 357424-12-5. Pack Sizes: 10 mg. Product ID: B2694-039627. Molecular formula: C12H13N3. Mole weight: 199.25. Custom synthesis is available. Send your inquiries for more information. |  London |
| 1,5-methano-1H-3-benzazepine | 1,5-methano-1H-3-benzazepine is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It is a prescription drug used to treat cigarette addiction. Group: Pharmaceutical. Alternative Names: 1-(7,8-dinitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one; 2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine; 1-(4,5-dinitro-10-aza-tricyclo[6.3.1.0(2,7)]dodeca-2(7),3,5-triene-10-yl)-2,2,2-trifluoro-ethanone; 2,2,2-Trifluoro-1-(1,2,4,5-tetrahydro-7,8-dinitro-1,5-methano-3H-3-benzazepin-3-yl)ethanone. CAS No. 230615-59-5. Pack Sizes: 1 g. Product ID: B2694-342826. Molecular formula: C13H10F3N3O5. Mole weight: 345.23. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Acetyl-3-chloro-10,11-dihydro-5H-dibenz[b,f]azepine | Carbamazepine Impurity 1 is an impurity of Carbamazepine, which is used in treatment of pain associated with trigeminal neuralgia. Group: Pharmaceutical. Alternative Names: 5-Acetyl-3-chloro-10,11-dihydro-5H-dibenz[b,f]azepine; 3-Chloro-5-acetyliminodibenzyl; 1-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethanone. CAS No. 25961-11-9. Pack Sizes: 1mg;1g;10g. Product ID: NP2924. Molecular formula: C16H14ClNO. Mole weight: 271.74. Custom synthesis is available. Send your inquiries for more information. | London |
| 6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione | 6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione, an organic compound of petite stature, finds widespread employment as a fundamental constituent in the production of diverse healing agents. Its competence as an anticonvulsant is well-documented and it serves as a propitious precursor in the construction of topoisomerase inhibitors and neuroprotective remedies. Group: Pharmaceutical. Alternative Names: Aldisin; 6,7-dihydropyrrolo[2,3-c]azepine-4,8(1H,5H)-dione; Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 6,7-dihydro-; 1H,4H,5H,6H,7H,8H-pyrrolo[2,3-c]azepine-4,8-dione. CAS No. 72908-87-3. Pack Sizes: 250 mg. Product ID: B0001-042431. Molecular formula: C8H8N2O2. Mole weight: 164.16. Custom synthesis is available. Send your inquiries for more information. | London |
| Carbamazepine EP Impurity G | Carbamazepine EP Impurity G is an impurity of Carbamazepine, a medication used in the treatment of epilepsy and neuropathic pain. Group: Pharmaceutical. Alternative Names: 10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide; 5-bromobenzo[b][1]benzazepine-11-carboxamide. CAS No. 59690-97-0. Pack Sizes: 25 mg. Product ID: B0517-468126. Molecular formula: C15H11BrN2O. Mole weight: 315.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Oxcarbazepine EP Impurity D | An impurity of Oxcarbazepine which is an anticonvulsant and mood stabilizing therapeutic for neuropathic pain, epilepsy, and affective disorders. Group: Pharmaceutical. Alternative Names: 5H-Dibenz[b,f]azepine-10,11-dione; Dibenzazepine-10,11-dione; Dibenzazepinodione. CAS No. 19579-83-0. Pack Sizes: 20 mg. Product ID: B2694-479847. Molecular formula: C14H9NO2. Mole weight: 223.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Oxcarbazepine EP Impurity I | An impurity of Oxcarbazepine which is an anticonvulsant and mood stabilizing therapeutic for neuropathic pain, epilepsy, and affective disorders. Group: Pharmaceutical. Alternative Names: 11-Keto Oxcarbazepine; 10,11-Dioxo-10,11-dihydro-5H-dibenzo(b,f)azepine-5-carboxamide; 5H-Dibenz(b,f)azepine-5-carboxamide, 10,11-dihydro-10,11-dioxo-; 10,11-Dioxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide; 10,11-Dihydro-10,11-dioxo Carbamazepine; 10,11-Dihydro-10,11-dioxo-5H-dibenz[b,f]azepine-5-carboxamide; Oxcarbazepine Related Compound F; Carbamazepinedione. CAS No. 537693-29-1. Pack Sizes: 2 mg. Product ID: B2694-477714. Molecular formula: C15H10N2O3. Mole weight: 266.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Benazepril EP Impurity G | Benazepril EP Impurity G is an ethyl ester derivative of Benazepril, which is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Group: Pharmaceutical. Alternative Names: Benazepril Related Compound G; Benazepril USP Related Compound G; Benazepril ethyl ester; (S)-Ethyl 2-(((S)-1-(2-ethoxy-2-oxoethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)amino)-4-phenylbutanoate; (3-(1-Ethoxycarbonyl-3-phenyl-(1S)-propyl)amino-2,3,4,5-tetrahydro-2-oxo-1H-1-(3S)-benzazepine)-1-acetic Acid ethyl Ester. CAS No. 103129-58-4. Pack Sizes: 25 mg. Product ID: B1370-151604. Molecular formula: C26H32N2O5. Mole weight: 452.54. Custom synthesis is available. Send your inquiries for more information. | London |
| Benazepril hydrochloride | Benazepril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Group: Pharmaceutical. Alternative Names: 2-((S)-3-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid hydrochloride; 1H-1-Benzazepine-1-acetic acid, 3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, hydrochloride (1:1), (3S)-; 1H-1-Benzazepine-1-acetic acid, 3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, (3S)-; 1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, [S-(R*,R*)]-; CGS 14824A; CGS 14824A HCl; Lotensin; Lotension. CAS No. 86541-74-4. Pack Sizes: 1mg;1g;10g. Product ID: NP3422. Molecular formula: C24H28N2O5.HCl. Mole weight: 460.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Epinastine hydrobromide | Epinastine is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. Group: Pharmaceutical. Alternative Names: (+/-)-3-amino-9,13b-dihydro-1h-dibenz[c,f]imidazo[1,5-a]azepine hydrobromide; Epinastine HBr. CAS No. 127786-29-2. Pack Sizes: 250 mg. Product ID: B2699-009500. Molecular formula: C16H15N3.HBr. Mole weight: 330.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Glucosepane | Glucosepane is a potential target for the research of diabetes and aging-related diseases. It is a type of advanced glycation end-product that accumulates in various tissues, leading to tissue damage and dysfunction. Inhibition of glucosepane formation may help prevent diabetic complications and delay the onset of age-related diseases. Group: Pharmaceutical. Alternative Names: Glucosepan; (alphaS,6R,7S)-alpha-Amino-2-[[(4S)-4-amino-4-carboxybutyl]amino]-6,7,8,8a-tetrahydro-6,7-dihydroxyimidazo[4,5-b]azepine-4(5H)-hexanoic acid. CAS No. 257290-23-6. Pack Sizes: 5 mg. Product ID: B1370-001549. Molecular formula: C18H32N6O6. Mole weight: 428.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Motolimod | Motolimod is a small-molecule agonist of TLR8, with potential immunostimulating and antineoplastic activities. Group: Pharmaceutical. Alternative Names: VTX-2337; VTX 2337; VTX2337; Motolimod; 2-amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide. CAS No. 926927-61-9. Pack Sizes: 100 mg. Product ID: B0084-462238. Molecular formula: C28H34N4O2. Mole weight: 458.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Mozavaptan | Mozavaptan (OPC-31260) inhibits AVP binding to V1 and V2 receptors in a competitive manner. Uses: Antidiuretic hormone receptor antagonists. Group: Pharmaceutical. Alternative Names: N-(4-(5-(dimethylamino)-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide; OPC-31260; OPC 31260; OPC31260; Mozavaptan. CAS No. 137975-06-5. Pack Sizes: 500 mg. Product ID: B2693-058123. Molecular formula: C27H29N3O2. Mole weight: 427.54. Custom synthesis is available. Send your inquiries for more information. | London |
| VPA-985 | VPA-985, an azepine compound, has been found to be a Vasopressin receptor antagonist that could be used in some cardiovascular disease therapy like hyponatraemia. Uses: Drug used in the treatment and prevention of cardiovascular diseases. Group: Pharmaceutical. Alternative Names: CRTX-080; CRTX080; CRTX 080; VPA-985; VPA985; VPA 985; WAY-VPA-985; Lixivaptan; N-[3-Chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methylbenzamide;Lixivaptan; VPA-985. CAS No. 168079-32-1. Pack Sizes: 25 mg. Product ID: B0084-060639. Molecular formula: C27H21ClFN3O2. Mole weight: 473.94. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Group: Pharmaceutical. Alternative Names: 3-(3-chloropropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one; 3-(3-chloropropyl)-7,8-dimethoxy-2,3-dihydro-1H-3-benzazepin-2-one; 3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one. CAS No. 85175-59-3. Pack Sizes: 1mg;1g;10g. Product ID: NP3534. Molecular formula: C15H18ClNO3. Mole weight: 295.76. Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Fluoro-4,5-dihydro-1H-azepino[5,4,3-CD]indol-6(3H)-one | 8-Fluoro-4,5-dihydro-1H-azepino[5,4,3-CD]indol-6(3H)-one is a useful research chemical. Group: Pharmaceutical. Alternative Names: 8-fluoro-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indol-6-one; 8-Fluoro-1,3,4,5-tetrahydro-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one; 8-Fluoro-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one. CAS No. 1408282-26-7. Pack Sizes: 10 g. Product ID: BB044626. Molecular formula: C11H9FN2O. Mole weight: 204.2. Custom synthesis is available. Send your inquiries for more information. | London |
| AC 41848 | AC 41848 is a potent, cell permeable, and subtype selective retinoic acid receptor RARγ agonist with an EC50 of 5.9 μM. Group: Pharmaceutical. Alternative Names: 1-[(2,4-Dichlorophenyl)methyl]-6,7,8,9-tetrahydro-3-phenyl-5H-imidazo[1,2-a]azepinium Bromide; 1-(2,4-Dichlorobenzyl)-3-phenyl-1,5,6,7,8,9-hexahydroimidazo[1,2-a]azepin-4-ium bromide; 5H-Imidazo[1,2-a]azepinium, 1-[(2,4-dichlorophenyl)methyl]-6,7,8,9-tetrahydro-3-phenyl-, bromide (1:1). CAS No. 400856-69-1. Pack Sizes: 1mg;1g;10g. Product ID: 400856-69-1. Molecular formula: C21H21BrCl2N2. Mole weight: 452.21. Custom synthesis is available. Send your inquiries for more information. Categories: AC41848. | London |
| Balanol | It is produced by the strain of Streptomyces sp. Tu 4128. Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA). It is an important target in oncology. Group: Pharmaceutical. Alternative Names: 4-(2-Carboxy-6-hydroxybenzoyl)-3,5-dihydroxybenzoic Acid (3R,4R)-Hexahydro-3-[(4-hydroxybenzoyl)amino]-1H-azepin-4-yl Ester; (3R-trans)-Balanol; (-)-Balanol; Azepinostatin; Ophiocordin. CAS No. 63590-19-2. Pack Sizes: 1mg;1g;10g. Product ID: BBF-00627. Molecular formula: C28H26N2O10. Mole weight: 550.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Dehydro Ivabradine Oxalate | Dehydro Ivabradine Oxalate is a potent pharmaceutical compound used in the research of cardiovascular diseases, specifically targeting heart failure and chronic stable angina. This compound acts as a selective inhibitor of the If current in sinoatrial node cells. Group: Pharmaceutical. Alternative Names: 3-{3-[(3,4-Dimethoxy-bicyclo[4.2.0]octa-1(6),2,4-trien-7-ylmethyl)-methyl-amino]-propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one; compound with oxalic acid. CAS No. 1346558-08-4. Pack Sizes: 10 mg. Product ID: B2694-473449. Molecular formula: C29H36N2O9. Mole weight: 556.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Demethylcephalotaxinone | Demethylcephalotaxinone is a natural alkaloid compound found in several plants. Group: Pharmaceutical. Alternative Names: Desmethylcephalotaxinone;(S)-1-hydroxy-5,6,8,9-tetrahydro-4H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-2(3H)-one. CAS No. 51020-45-2. Pack Sizes: 1 mg. Product ID: NP0287. Molecular formula: C17H17NO4. Mole weight: 299.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Hydroxy Ivabradine | An impurity of Ivabradine, a medication used to reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure. Group: Pharmaceutical. Alternative Names: 1,3,4,5-Tetrahydro-3-(3-hydroxypropyl)-7,8-dimethoxy-2H-3-benzazepin-2-one; 3-(3-Hydroxypropyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one. CAS No. 1235547-07-5. Pack Sizes: 2 mg. Product ID: B2694-473453. Molecular formula: C15H21NO4. Mole weight: 279.34. Custom synthesis is available. Send your inquiries for more information. | London |
| lofepramine hydrochloride | Lofepramine is a tricyclic antidepressant (TCA) indicated for the treatment of depression. It functions via inhibiting 5-HT and NA reuptake. Group: Pharmaceutical. Alternative Names: N-(4-CHLOROBENZOYLMETHYL)-3-(10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPIN-5-YL)-N-METHYLPROPYLAMINE HYDROCHLORIDE; LOFEPRAMINE HCL; LOFEPRAMINE HYDROCHLORIDE; 4'-chloro-2-((3-(10,11-dihydro-5h-dibenz(b,f)azepin-5-yl)propyl)methylamino); acetophenone,4'-chloro-2-((3-(1. CAS No. 26786-32-3. Pack Sizes: 50 g. Product ID: B2693-064646. Molecular formula: C26H28Cl2N2O. Mole weight: 455.426. Custom synthesis is available. Send your inquiries for more information. | London |
| LY-411575 | LY-411575, also known as LSN-411575, is a potent, cell-permeable γ-secretase inhibitor (IC50 = 0.078 nM/0.082 nM in membrane-assay/in cell-basedγ-secretase assays) and also inhibits Notch clevage (IC50 = 0.39 nM). Group: Pharmaceutical. Alternative Names: (αS)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxybenzeneacetamide; LY 411,575; LY 411575; LY411575; (S)-2-((S)-2-(3,5-Difluorophenyl)-2-hydroxyacetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide. CAS No. 209984-57-6. Pack Sizes: 25 mg. Product ID: B0084-087322. Molecular formula: C26H23F2N3O4. Mole weight: 479.48. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Azelastine | N-Desmethyl Azelastine is the main metabolite of Azelastine. Azelastine is a potent, selective and second-generation histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor. Group: Pharmaceutical. Alternative Names: Desmethylazelastine; 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone; Azelastine Hydrochloride Impurity. CAS No. 47491-38-3. Pack Sizes: 50 mg. Product ID: B2694-467139. Molecular formula: C21H22ClN3O. Mole weight: 367.88. Custom synthesis is available. Send your inquiries for more information. | London |
| Rucaparib | Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway. So, rucaparib has been also found to be most effective in cells deficient in DNA repair, where the cells deficient are caused by exposure to genotoxic agents, such as irradiation produces DNA damage and its toxicity is augmented when the DNA repair is impaired. Increased radiosensitivity in presence of rucaparib was associated with persistent DNA breaks as determined by gamma-H2AX and p53BP1 foci. Rucaparib radiosensitizes prostate cancer cells, most effectively those that are PTEN-deficient and are expressing ETS gene fusion proteins, which inhibits NHEJ DNA repair. Uses: Cancer therapy. Group: Pharmaceutical. Alternative Names: 8-Fluoro-2-(4-((methylamino)methyl)phenyl)-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd)indol-6-one; Rucaparib free base, AG-14447; AG 14447; AG14447; Rubraca. CAS No. 283173-50-2. Pack Sizes: 250 mg. Product ID: B2693-104639. Molecular formula: C19H18FN3O. Mole weight: 323.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Rucaparib monocamsylate | Rucaparib camsylate is an inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, which work in DNA repair process. It was approved for the treatment of ovarian cancer, and Rubraca is proved to be a monotherapy for the patients deleterious BRCA mutation associated advanced ovarian cancer who were treated with two or more chemotherapies. Group: Pharmaceutical. Alternative Names: Rucaparib camsylate; Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S,4R)-, compd. with 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one (1:1); 8-fluoro-5-(4-((methylamino)methyl)phenyl)-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-1-one ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate (1:1); 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid (1:1). CAS No. 1859053-21-6. Pack Sizes: 100 mg. Product ID: B0084-007117. Molecular formula: C29H34FN3O5S. Mole weight: 555.66. Custom synthesis is available. Send your inquiries for more information. | London |
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