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Avermectin B1b is the minor component of the commercially available anthelmintic marketed as Abamectin. It is used broadly against nematodes, ticks, flies, and ants. Group: Pharmaceutical. Alternative Names: Ivermectin EP Impurity B; 5-O-Demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-avermectin A1a; Doramectin Impurity 2. CAS No. 65195-56-4. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04030. Molecular formula: C47H70O14. Mole weight: 859.05. Custom synthesis is available. Send your inquiries for more information.
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Abamectin
Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. It is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b, which have very similar biological and toxicological properties. Avermectin B1 is a natural fermentation product of this bacterium. Group: Pharmaceutical. Alternative Names: Avomec; Agri-Mek; Avid; Agrimek; Vertimec; Affirm; Zephyr; MK 936; MK 0936; NSC 758202; Avermectin B1; MK-936; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin B1 deriv.; A 14906; A 8612; Abamektin; Abamitel; Abarex; Abastate; Abastate EW; Abathor; Abba; Agador; AgMectin; Agri-Mek; Agri-Mek SC; Agrimec; Avermectin B1a-Avermectin B1b mixt.; Aversectin S; Avert; Avicta; Avicta 400FS; Avid 0.15EC; CHA 2061; CHA 2062; Dalamectin; Dalamektin; Epi-Mek; Fitoverm; Fitoverm M; Genesis Oral Drench; Genesis Pour-on for Cattle and Deer; Kraft; KRAFT 36 EC; L 676; Lirosect; Lyrosekt; Mectin; Phytoverm; PT 310; Rustomectin; STAN; Temprano; Vermitec; Vertigo (pesticide); Vertigo 018EC; Vertimec 018SC; Zoro. CAS No. 71751-41-2. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05730. Molecular formula: C48H72O14.C47H70O14. Mole weight: 1732.14. Custom synthesis is available. Send your inquiries for more information.
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Avermectin B2a
Avermectin B2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Group: Pharmaceutical. Alternative Names: Ivermectin EP Impurity C; (23S)-5-O-demethyl-23-hydroxy-22,23-dihydro-avermectin A1a. CAS No. 65195-57-5. Pack Sizes: 1mg;1g;10g. Product ID: BBF-00230. Molecular formula: C48H74O15. Mole weight: 891.09. Custom synthesis is available. Send your inquiries for more information.
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Eprinomectin B1a
It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination. Members of the Avermectin/Milbemycin class exert their insecticidal/anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. Group: Pharmaceutical. Alternative Names: (4''R)-4''-(Acetylamino)-5-O-demethyl-4''-deoxyavermectin A1a; Avermectin A1a, 4'-(acetylamino)-5-O-demethyl-4'-deoxy-, (4'R)-; Eprinomectin component B1a. CAS No. 133305-88-1. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04244. Molecular formula: C50H75NO14. Mole weight: 914.13. Custom synthesis is available. Send your inquiries for more information.
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Eprinomectin B1b
It is a semi-synthetic analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination followed by acetylation. It is the minor component (<10%) of the commercial product for endo- and exo-parasite control, eprinomectin. It is a potent insecticide and acaricide. Group: Pharmaceutical. Alternative Names: (4''R)-4''-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-25-(1-methylethyl)avermectin A1a; Eprinomectin component B1b. CAS No. 133305-89-2. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04245. Molecular formula: C49H73NO14. Mole weight: 900.1. Custom synthesis is available. Send your inquiries for more information.
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Eprinomectin-[d3]
One of the isotope labelled form of Eprinomectin, which could be used as an antiparasitic agent. Group: Pharmaceutical. Alternative Names: (4''R)-4''-(Acetylamino)-5-O-demethyl-4''-deoxyavermectin A1a-d3 compound with (4''R)-4''-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-25-(1-methylethyl)avermectin A1a-d3. Pack Sizes: 1 mg. Product ID: BLP-014123. Molecular formula: C50D3H72NO14.C49D3H70NO14. Mole weight: 917.17 (B1a); 903.14 (B1b). Custom synthesis is available. Send your inquiries for more information.
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Ivermectin
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Group: Pharmaceutical. Alternative Names: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). CAS No. 70288-86-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05776. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin B1a-[d2]
Ivermectin B1a-[d2] is the labelled analogue of Ivermectin B1a, which is a major component of ivermectin and a semi-synthetic derivative of abamectin. It is a mixture including not less than 80% component B1a and not more than 20% component B1b. It is used as an antihelmintic. Group: Pharmaceutical. Alternative Names: Ivermectin B1a-d2; 5-O-Demethyl-22,23-dihydro-avermectin A1a-d2; 2,23-Dihydroavermectin B1a-d2; Dihydroavermectin B1a-d2. Pack Sizes: 1mg;1g;10g. Product ID: BLP-013039. Molecular formula: C48H72D2O14. Mole weight: 877.11. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin B1b
Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Group: Pharmaceutical. Alternative Names: Ivermectin B1b;Avermectin H2B1b;Ivermectin Component B1b;dihydroavermectin B1b;70209-81-3;22,23-dihydroavermectin B1b;0W28CYI3TU;CHEBI:63943;Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-;(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one;UNII-0W28CYI3TU;Stromectol (TN);Soolantra (TN);EINECS 274-384-5;Sklice (TN);H2B1b;CHEMBL552;Ivermectin (JAN/USP/INN);SCHEMBL313003;DTXSID3023182;VARHUCVRRNANBD-PVVXTEPVSA-N;IVERMECTIN COMPONENT B1B [MI];HY-125729;CS-0093431;NS00093438;D00804;Q27132925;5-O-DEMETHYL-25-DE(1-METHYLPROPYL)-22,23-DIHYDRO-25-(1-METHYLETHYL)AVERMECTIN A1A;Avermectin A(sub 1a), 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-. CAS No. 70209-81-3. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03934. Molecular formula: C20H38N6O4. Mole weight: 426.6. Custom synthesis is available. Send your inquiries for more information.
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