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| Product | Description | |
|---|---|---|
| AT-265 | AT-265 is a nucleoside antibiotic produced by Streptomyces rishiensis. It has anti-gram-positive and negative bacteria activity. Group: Pharmaceutical. Alternative Names: 5'-Sulfamoyl-2-chloroadenosine; 2-chloro-5'-o-sulfamoyladenosine; Antibiotic AT 265. CAS No. 66522-52-9. Pack Sizes: 5 mg. Product ID: BBF-03211. Molecular formula: C10H13ClN6O6S. Mole weight: 380.77. Custom synthesis is available. Send your inquiries for more information. |  London |
| AC 265347 | AC 265347 is a CaSR biased allosteric modulator (pEC50 = 7.8-8.1) that bias signaling towards the accumulation of PERK1/2 and IP1. AC 265347 stimulates CaSR signaling in cellular proliferation and phosphatidyl inositol (PI) hydrolysis assays. It significantly activates human GABAB or type I PTH receptors. Group: Pharmaceutical. Alternative Names: AC 265347; AC-265347; AC265347; α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol; 1-(1,3-benzothiazol-2-yl)-1-(2,4-dimethylphenyl)ethanol. CAS No. 1253901-26-6. Pack Sizes: 1mg;1g;10g. Product ID: 1253901-26-6. Molecular formula: C17H17NOS. Mole weight: 283.39. Custom synthesis is available. Send your inquiries for more information. | London |
| AG 1406 | AG 1406 is an inhibitor of tyrosine phosphorylation. Group: Pharmaceutical. Alternative Names: 2-[[4-hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]propanedinitrile; Propanedinitrile, [[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-; CTK2G2659; AG1406; CTK2G 2659; AG 1406; CTK2G-2659; AG-1406. CAS No. 71308-34-4. Pack Sizes: 25 mg. Product ID: B0084-284859. Molecular formula: C16H18N2O. Mole weight: 254.333. Custom synthesis is available. Send your inquiries for more information. | London |
| Azacytidine-[13C5] | Labelled Azacytidine, produced by the strain of Streptoverticillium ladakanus var. ladakanus UC-2654. Azacitidine (Vidaza) is a chemotherapy drug used to treat conditions that affect the blood and the bone marrow, called myelodysplastic syndromes (MDS). It may also be used to treat other cancers, such as acute myeloid leukaemia (AML) or chronic myelomonocytic leukaemia (CMML). It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.6 μM for in vitro anti-myeloma activity) and cancer (IC50s ~ 0.4 μM for inhibiting proliferation of various cancer cell lines). It can also act as a demethylating agent by inhibiting DNA methyltransferase. Group: Pharmaceutical. Alternative Names: 4-Amino-1-[3,4-dihydroxy-5-(hydroxy(113C)methyl)(2,3,4,5-13C4)oxolan-2-yl]-1,3,5-triazin-2-one. Pack Sizes: 1 mg. Product ID: BLP-003371. Molecular formula: C3[13C]5H12N4O5. Mole weight: 249.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Dovitinib | Dovitinib (TKI258) potently inhibited FLT3, c-KIT, FGFR, VEGFR1/2/3, PDGFRß and CSF-1R with IC50 values of 1, 2, 5, 10, 8, 27, 36 nM respectively. Dovitinib selectively blocked the growth of wild-type (WT) or activated mutant FGFR3-transformed B9 cells and human myeloma cell lines. Dovitinib was an effective treatment in a xenograft mouse model of FGFR3 multiple myeloma. Group: Pharmaceutical. Alternative Names: Dovitinib, TKI258; TKI 258;TKI-258; CHIR 265; CHIR265; CHIR-265; RAF-265; RAF 265; RAF265. CAS No. 405169-16-6. Pack Sizes: 50 mg. Product ID: B2693-091881. Molecular formula: C21H21FN6O. Mole weight: 392.429. Custom synthesis is available. Send your inquiries for more information. | London |
| Pentyl phenoxyacetate | Pentyl phenoxyacetate. Group: Pharmaceutical. Alternative Names: Phenoxyacetic acid pentyl ester. CAS No. 74525-52-3. Pack Sizes: 100 mg. Product ID: B1370-265471. Molecular formula: C13H18O3. Mole weight: 222.28. Custom synthesis is available. Send your inquiries for more information. | London |
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