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| Product | Description | |
|---|---|---|
| 11a-Hydroxy-16,17a-epoxyprogesterone | 11a-Hydroxy-16,17a-epoxyprogesterone is a synthetic steroid in the realm of pharmacotherapy for inflammatory and autoimmune disorders. Demonstrating notable potential for addressing maladies including but not limited to rheumatoid arthritis, lupus, and asthma through its mechanisms of immune modulation and anti-inflammatory properties. Group: Pharmaceutical. Alternative Names: 11a-Hydroxy-16,17a-epoxyprogesterone19427-36-216alpha,17-Epoxy-11alpha-hydroxypregn-4-ene-3,20-dione(1S,2S,4R,6S,7S,9R,10S,11R)-6-acetyl-9-hydroxy-7,11-dimethyl-5-oxapentacyclo[8.8.0.02,7.04,6.011,16]octadec-15-en-14-one11a-Hydroxy epoxy progesterone. CAS No. 19427-36-2. Pack Sizes: 1mg;1g;10g. Product ID: 19427-36-2. Molecular formula: C21H28O4. Mole weight: 344.44. Custom synthesis is available. Send your inquiries for more information. |  London |
| 11β-Hydroxy-2'-methyl-5'βH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione | An intermediate of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus. Group: Pharmaceutical. Alternative Names: (11β,16β)-11-hydroxy-2'-methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; (11β,16β)-11β-hydroxy-2'-methyl-5βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; 11β-hydroxy-2'-methyl-5'βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione. CAS No. 13649-88-2. Pack Sizes: 1mg;1g;10g. Product ID: NP3150. Molecular formula: C23H29NO4. Mole weight: 383.48. Custom synthesis is available. Send your inquiries for more information. | London |
| 17-Oxo Dexamethasone | 17-Oxo Dexamethasone is an exceedingly influential synthetic glucocorticoid imbued with remarkable anti-inflammatory and immunosuppressive attributes. This paramount product finds its purpose in studying a myriad of perplexing inflammatory ailments, most notably rheumatoid arthritis , asthma and allergic reactions. Uses: A metabolite of dexamethasone. Group: Pharmaceutical. Alternative Names: 9-Fluoro-11-hydroxy-16-methyl-(11β,16α ) Androsta-1,4-diene-3,17-dione; 9-Fluoro-11β-hydroxy-16α-methyl Androsta-1,4-diene-3,17-dione; NSC 50909. CAS No. 1880-61-1. Pack Sizes: 25 mg. Product ID: B0731-263435. Molecular formula: C20H25FO3. Mole weight: 332.41. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Aminoethylmethylsulfone hydrochloride | 2-Aminoethylmethylsulfone hydrochloride is a compound extensively utilized within the biomedical realm due to its acclaimed therapeutic potential across a multifaceted spectrum of ailments, specifically targeting rheumatoid arthritis and osteoarthritis. Its profound anti-inflammatory and analgesic attributes render it a prime contender for combatting afflictions characterized by pain and inflammation. Group: Pharmaceutical. CAS No. 104458-24-4. Pack Sizes: 1mg;1g;10g. Product ID: 104458-24-4. Molecular formula: C3H9NO2S·HCl. Mole weight: 159.63. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Cyanoadenosine | 2-Cyanoadenosine is a biomedical compound used in the treatment of autoimmune diseases and chronic inflammatory conditions. It exhibits immunosuppressive effects by modulating the immune response. PubMed studies suggest its potential in managing rheumatoid arthritis, lupus erythematosus, and multiple sclerosis. Group: Pharmaceutical. Alternative Names: Adenosine, 2-cyano-; 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine-2-carbonitrile. CAS No. 79936-11-1. Pack Sizes: 50 mg. Product ID: B1370-339258. Molecular formula: C11H12N6O4. Mole weight: 292.25. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile | One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: N-Methyl-N-(3R,4R)-1-cyanoacetyl-4-methylpiperidin-3-yl-2-chloro-7-deazapurine-6-amine; Tofacitinib Impurity 21. CAS No. 1616761-00-2. Pack Sizes: 25 mg. Product ID: B1370-379650. Molecular formula: C16H19ClN6O. Mole weight: 346.81. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-((3R,4R)-4-methyl-3-(methylamino)piperidin-1-yl)-3-oxopropanenitrile hydrochloride | An impurity of Tofacitinib, a Janus kinase inhibitor that could be used against rheumatoid arthritis. Group: Pharmaceutical. CAS No. 1640971-87-4. Pack Sizes: 5 mg. Product ID: B2694-063174. Molecular formula: C10H18ClN3O. Mole weight: 231.72. Custom synthesis is available. Send your inquiries for more information. | London |
| (3R,4R)-1-Benzyl-3-(methylamino)-4-methylpiperidine Dihydrochloride | (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. Alternative Names: (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine;dihydrochloride; (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine;dihydrochloride. CAS No. 1062580-52-2. Pack Sizes: 100 g. Product ID: B2694-150044. Molecular formula: C14H24Cl2N2. Mole weight: 291.26. Custom synthesis is available. Send your inquiries for more information. | London |
| (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine | (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. CAS No. 1638499-31-6. Pack Sizes: 50 mg. Product ID: B2694-080065. Molecular formula: C14H22N2. Mole weight: 218.34. Custom synthesis is available. Send your inquiries for more information. | London |
| (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine | (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. Alternative Names: (3S,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine. CAS No. 1638499-33-8. Pack Sizes: 25 mg. Product ID: B2694-111800. Molecular formula: C14H22N2. Mole weight: 218.34. Custom synthesis is available. Send your inquiries for more information. | London |
| (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride | (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. Alternative Names: Tofacitinib impurity G; Tofacitinib Impurity 02; cis-1-Benzyl-3-(methylamino)-4-methylpiperidine dihydrochloride. CAS No. 1354486-07-9. Pack Sizes: 5 g. Product ID: B2694-088366. Molecular formula: C14H24Cl2N2. Mole weight: 291.3. Custom synthesis is available. Send your inquiries for more information. | London |
| 4'-Bromo-4-cyanobiphenyl | 4'-Bromo-4-cyanobiphenyl is a biologically active agent that serves as a crucial constituent in the synthesis of medicinal drugs utilized in the remedy of different ailments, including cancer, autoimmune disorders, and arthritis. Its versatile chemical properties allow for enhanced efficacy in drug development, making it a valuable pharmaceutical intermediate. Group: Pharmaceutical. Alternative Names: 4'-bromo-[1,1'-Biphenyl]-4-carbonitrile. CAS No. 57774-35-3. Pack Sizes: 25 g. Product ID: B2699-249367. Molecular formula: C13H8BrN. Mole weight: 258.11. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(1H-1,2,4-Triazol-1-ylmethyl)-1H-indole-3-ethanol | 5-(1H-1,2,4-Triazol-1-ylmethyl)-1H-indole-3-ethanol is an intriguing compound entity, showcasing unwavering anti-inflammatory and antioxidant attribute. This compound aids in studying maladies besieged by inflammation, notably rheumatoid arthritis, alongside conditions grappling with oxidative stress. Group: Pharmaceutical. Alternative Names: Des(dimethylamino)hydroxyrizatriptan; 2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanol; 2-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1H-indol-3-yl)ethanol; GUF1804OA0; 2-(5-[1,2,4]Triazol-1-ylmethyl-1H-indol-3-yl)-ethanol; 1H-Indole-3-ethanol, 5-(1H-1,2,4-triazol-1-ylmethyl)-; 2-(5-(1H-1,2,4-Triazol-1-ylmethyl)-1H-indol-3-yl)ethanol; 2-(5-((1H-1,2,4-triazol-1-yl)methyl)-1H-indol-3-yl)ethan-1-ol; 2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethan-1-ol; UNII-GUF1804OA0; 5-(1H-1,2,4-triazol-1-ylmethyl)-1H-Indole-3-ethanol; Rizatriptan benzoate impurity F [EP]; SCHEMBL4344147; DTXSID20166834; WXWBRTKSGCYLQS-UHFFFAOYSA-N; 2-[5-(1,2,4-Triazol-1-ylmethyl)-1H-indol-3-yl]ethyl alcohol; MFCD03840590; CS-0340423; FT-0731877; A899332; Q27279286; RIZATRIPTAN BENZOATE IMPURITY F [EP IMPURITY]. CAS No. 160194-39-8. Pack Sizes: 25 mg. Product ID: B1586-085114. Molecular formula: C13H14N4O. Mole weight: 242.28. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Methyl-3,4-diphenyl-4,5-dihydroisoxazol-5-ol | An intermediate for the preparation of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Uses: Intermediate for the preparation of valdecoxib. Group: Pharmaceutical. Alternative Names: 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol. CAS No. 181696-73-1. Pack Sizes: 200 mg. Product ID: B2694-053919. Molecular formula: C16H15NO2. Mole weight: 253.3. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-O-(E)-p-Coumaroylquinic acid | 5-O-(E)-p-Coumaroylquinic acid, an anti-inflammatory compound, exhibits efficacy in the reduction of inflammation, as well as the alleviation of pain and swelling commonly observed in Rheumatoid Arthritis, Osteoarthritis, and other inflammatory diseases. Endowed with multiple therapeutic benefits, this drug is a preferred choice prescribed by medical professionals to ensure the complete restoration of a patient's health and well-being. Group: Pharmaceutical. Alternative Names: 2-Coumaroylquinic acid;1899-30-5;5746-55-4;trans-5-O-(4-coumaroyl)-D-quinic acid;5-p-coumaroylquinic acid;3-p-coumaroylquinic acid;p-Coumaroyl quinic acid;o-Coumaroylquinic acid;(1S,3R,4R,5R)-1,3,4-trihydroxy-5-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxycyclohexane-1-carboxylic acid;CHEBI:15937;5-O-(E)-p-Coumaroylquinic acid;4C4BU5688G;trans-5-O-(4-Coumaroyl)-D-quinate;(1R,3S,4R,5S)-1,3,4-TRIHYDROXY-. CAS No. 5746-55-4. Pack Sizes: 1 mg. Product ID: B2705-383272. Molecular formula: C27H30O8. Mole weight: 482.5. Custom synthesis is available. Send your inquiries for more information. | London |
| 9-Phenanthrenemethanol | 9-Phenanthrenemethanol, a well-known intermediate in organic synthesis, presents itself as a promising compound with its anti-inflammatory and analgesic properties. Its therapeutic potential is particularly notable in the management of pain and inflammatory diseases, such as arthritis, but further investigation in clinical settings is required to fully harness its benefits. Group: Pharmaceutical. Alternative Names: phenanthren-9-ylmethanol; (9-Phenanthryl)methanol; 9-(Hydroxymethyl)phenanthrene; 9-Hydroxymethylphenanthrene; 9-Phenanthrenemethanol. CAS No. 4707-72-6. Pack Sizes: 100 mg. Product ID: B0001-092780. Molecular formula: C15H12O. Mole weight: 208.26. Custom synthesis is available. Send your inquiries for more information. | London |
| A1F N-Glycan | A1F N-Glycan, the versatile biomolecule employed by the biomedical industry, is the key player in the in-depth scrutiny and diagnosis of diverse disorders - think cancer, Alzheimer's, and rheumatoid arthritis. Its multifaceted involvement in cell signaling pathways has made it a go-to diagnostic marker in countless clinical settings. Furthermore, the therapeutic potential of A1F N-Glycan has not gone unexploited; it forms the crux of several drug formulations aimed at combating these afflictions. Group: Pharmaceutical. Alternative Names: Monosialo (2,6), fucosylated biantennary (A1F); A1F glycan; FA2G2S1 Glycan; Mono-sialylated, galactosylated, core-fucosylated, bi-antennary N-linked glycan; Mannotriose-(fucosyl-di-[N-acetylglucosamine]), mono-sialyl-bis(galactosyl-N-acetylglucosaminyl); NeuNAc(Gal-GlcNAc)2Man3(GlcNAc)2Fuc; β-D-Glucopyranose, O-(N-acetyl-α-neuraminosyl)-[2→3(or 2→6)]-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→2)-O-α-D-mannopyranosyl-[1→3(or 1→6)]-O-[O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→2)-α-D-mannopyranosyl-[1→6(or 1→3)]]-O-β-D-mannopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-[6-deoxy-α-L-galactopyranosyl-(1→6)]-2-(acetylamino)-2-deoxy-. CAS No. 571188-30-2. Pack Sizes: 1mg;1g;10g. Produc | London |
| ABT 702 Dihydrochloride | ABT 702 Dihydrochloride is a potent and selective non-nucleoside adenosine kinase inhibitor with IC50 value of 1.7 nM. ABT 702 displays oral activity in animal models of pain and inflammation. In Mar 2005, ABT 702 was discontinued preclinical for Pain and Rheumatoid arthritis in USA. Uses: Anti-inflammation. Group: Pharmaceutical. Alternative Names: ABT702 Dihydrochloride; ABT-702 Dihydrochloride. CAS No. 1188890-28-9. Pack Sizes: 50 mg. Product ID: B2693-475131. Molecular formula: C22H21BrCl2N6O. Mole weight: 536.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Alfadolone | Alfadolone, a synthetic steroid hormone, is an effective anti-inflammatory agent that relieves pain and inflammation associated with diseases like arthritis. Further, it is increasingly employed for treating autoimmune disorders like lupus and multiple sclerosis. The mechanism of action of alfadolone involves hampering the production of bodily chemicals responsible for inflammation. Group: Pharmaceutical. Alternative Names: Pregnane-11,20-dione, 3,21-dihydroxy-, (3alpha,5alpha)-. CAS No. 14107-37-0. Pack Sizes: 25 mg. Product ID: B2699-222622. Molecular formula: C21H32O4. Mole weight: 348.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Angeloyl gomisin H | Angeloyl gomisin H is an intriguing natural compound isolated from Schisandra chinensis, showcasing remarkable anti-inflammatory and antioxidant properties, aiding in studying inflammatory afflictions, including arthritis. Group: Pharmaceutical. Alternative Names: Angeloylgomisin H; (2Z)-2-Methyl-2-butenoic acid (6S,7S,12aR)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester. CAS No. 66056-22-2. Pack Sizes: 20 mg. Product ID: NP3983. Molecular formula: C28H36O8. Mole weight: 500.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Baricitinib | Baricitinib is a selective and orally bioactive inhibitor of JAK1 and JAK2. It has been approved by FDA for the treatment of rheumatoid arthritis (RA). Uses: The treatment of rheumatoid arthritis (ra). Group: Pharmaceutical. Alternative Names: LY3009104; 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile; Olumiant. CAS No. 1187594-09-7. Pack Sizes: 1 g. Product ID: B0084-457382. Molecular formula: C16H17N7O2S. Mole weight: 371.419. Custom synthesis is available. Send your inquiries for more information. | London |
| Baricitinib phosphate | Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM). Baricitinib has been approved by FDA for the treatment of rheumatoid arthritis (RA). Group: Pharmaceutical. Alternative Names: INCB 028050; LY 3009104; INCB028050; LY3009104; LY-3009104; INCB-028050. CAS No. 1187595-84-1. Pack Sizes: 25 g. Product ID: B1370-463116. Molecular formula: C16H20N7O6PS. Mole weight: 469.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Benorilate | Benorilate, a nonsteroidal anti-inflammatory drug, is utilized in the management of pain and inflammation associated with conditions like rheumatoid arthritis and osteoarthritis. This prodrug undergoes conversion within the body to produce paracetamol and acetylsalicylic acid, resulting in a synergistic analgesic and anti-inflammatory action. Group: Pharmaceutical. Alternative Names: Benorilate; 5003-48-5; BENORYLATE; 4-acetamidophenyl 2-acetoxybenzoate;; Salipran. CAS No. 5003-48-5. Pack Sizes: 1mg;1g;10g. Product ID: 5003-48-5. Molecular formula: C17H15NO5. Mole weight: 313.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Benzoylmesaconine | Benzoylmesaconine is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: Mesaconine 14-benzoate. CAS No. 63238-67-5. Pack Sizes: 20 mg. Product ID: B0005-464497. Molecular formula: C31H43NO10. Mole weight: 589.67. Custom synthesis is available. Send your inquiries for more information. | London |
| Bulleyaconitine A | Bulleyaconitine A is an alkaloid found in Aconitum bulleyanum. It has analgesic and anti-inflammatory properties and has been used for the treatment of chronic pain and rheumatoid arthritis. Uses: Bulleyaconitine a, an active indegrent from aconitum bulleyanum diel, has been found to be effective in the treatment of chronic pain and rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: ((1-α,6-α,14-α,16-β)-8-(acetyloxy)-20-ethyl-13-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl)(4-methoxyphenyl)-methanone; 20-ethyl-13g-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl](4-methoxyphenyl)-methanone, [(1α,6α,14α,16β) -8-(acetyloxy)-. CAS No. 107668-79-1. Pack Sizes: 50 mg. Product ID: B0005-465163. Molecular formula: C35H49NO9. Mole weight: 627.76. Custom synthesis is available. Send your inquiries for more information. | London |
| Cathepsin S inhibitor | Cathepsin S is expressed in antigen-presenting cells and plays a role in invariant chain processing and major histocompatibility complex class II (MHCII) antigen presentation leading to CD4+ T-cell activation. An oral Cathepsin S inhibitor that blocks MHCII antigen presentation could result in a T-cell-selective immunosuppressant agent with improved safety over the current standard of care for the treatment of rheumatoid arthritis, psoriasis, multiple sclerosis and other autoimmune-based inflammatory diseases. Group: Pharmaceutical. Alternative Names: LY3000328; LY-3000328; LY 3000328. Cathepsin S inhibitor. CAS No. 1373215-15-6. Pack Sizes: 10 mg. Product ID: B0084-463202. Molecular formula: C25H29FN4O5. Mole weight: 484.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib | Celecoxib is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID) used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. Uses: Cyclooxygenase 2 inhibitors. Group: Pharmaceutical. Alternative Names: Celebra; Celebrex; SC 58635; Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; Celecox; Celocoxib; Eurocox; Medicoxib; Onsenal; Xilebao; YM 177. CAS No. 169590-42-5. Pack Sizes: 5 g. Product ID: B0084-451901. Molecular formula: C17H14F3N3O2S. Mole weight: 381.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Cyclic citrullinated peptide | Cyclic citrullinated peptide is a synthetic cyclic peptide combined with the amino acid citrullinated. Can be used to diagnose rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: His-Gln-Cys-His-Gln-Glu-Ser-Thr-Cit-Gly-Arg-Ser-Arg-Gly-Arg-Cys-Gly-Arg-Ser-Gly-Ser (Disulfide bond Cys3/Cys16). Pack Sizes: 5 mg. Product ID: BAT-006243. Molecular formula: C87H145N41O32S2. Mole weight: 2341.46. Custom synthesis is available. Send your inquiries for more information. | London |
| CZ415 | CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM; 2. inhibition of Akt (mTORC2 substrate) phosphorylation in HEK293T: IC50 = 14.8 nM; 3. inhibition of IFNγ release in stimulated human whole blood: IC50 = 226 nM. Group: Pharmaceutical. Alternative Names: CZ415; CZ-415; CZ 415; (S)-1-(4-(7,7-dimethyl-4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea. CAS No. 1429639-50-8. Pack Sizes: 5 mg. Product ID: B0084-474821. Molecular formula: C22H29N5O4S. Mole weight: 459.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Derrisisoflavone I | Derrisisoflavone I is a extensively utilized natural compound in the biomedical industry, presenting itself as a promising candidate for drug development of a range of afflictions characterized by inflammation, such as rheumatoid arthritis is asthma and inflammatory bowel disease. Group: Pharmaceutical. Alternative Names: Derrisisoflavone I; AKOS040762672; 2172624-66-5. CAS No. 2172624-66-5. Pack Sizes: 1 mg. Product ID: NP2157. Molecular formula: C26H26O7. Mole weight: 450.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Dexamethasone 21-Palmitate | Dexamethasone 21-Palmitate is a derivative of Dexamethasone, a glucocorticoid with anti-inflammatory activity approved for the treatment of arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions. Group: Pharmaceutical. Alternative Names: Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11β,16α)-; Dexamethasone palmitate; Limethason; (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]pregna-1,4-diene-3,20-dione; Palmitic acid, 21-ester with 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione; Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-palmitate; Limethasone; Lipotalon. CAS No. 14899-36-6. Pack Sizes: 250 mg. Product ID: B0731-059277. Molecular formula: C38H59FO6. Mole weight: 630.87. Custom synthesis is available. Send your inquiries for more information. | London |
| Diacerein | Diacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis. Uses: Treatment of osteoarthritis. Group: Pharmaceutical. Alternative Names: Artrodar; Fisiodar; SF-277; Verboril; 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic Acid. CAS No. 13739-02-1. Pack Sizes: 100 g. Product ID: B1370-058058. Molecular formula: C19H12O8. Mole weight: 368.29. Custom synthesis is available. Send your inquiries for more information. | London |
| (Diacetyl)-α-MSH | (Diacetyl)-α-MSH, a synthetic peptide, has been investigated extensively for its prospective applications in the management of autoimmune and inflammatory ailments, like rheumatoid arthritis and multiple sclerosis. Its anti-inflammatory properties and the ability to modulate the immune system by regulating cytokine production have been well documented. Furthermore, its efficacy as a treatment option for melanoma and obesity has been studied due to its influence on melanocortin receptors. The compound offers remarkable potential as an agent for mitigating various diseases. Group: Pharmaceutical. Alternative Names: a-Melanotropin (swine), 1-(N,O-diacetyl-L-serine)-; Ac-Ser(Ac)-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2. CAS No. 71952-90-4. Pack Sizes: 5 mg. Product ID: BAT-006209. Molecular formula: C79H111N21O20S. Mole weight: 1706.92. Custom synthesis is available. Send your inquiries for more information. | London |
| Dihydrocyclosporin A | An impurity of Cyclosporine. Cyclosporine is a powerful immunosuppressive medication derived from a fungal source. It is primarily used to prevent organ rejection in transplant recipients by inhibiting the activation of T-cells, a key component of the immune system. Cyclosporine is also used to treat certain autoimmune diseases, such as psoriasis and rheumatoid arthritis, where the immune system mistakenly attacks the bodys own tissues. Group: Pharmaceutical. Alternative Names: Ciclosporin Impurity B; 1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)octanoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]; Dihydrociclosporin A; 6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A; 6-[(3R,4R)-3-Hydroxy-N,4-dimethyl-L-2-aminooctanoic acid]cyclosporin A; Dihydro Cyclosporin A; Dihydrocyclosporine A; Cyclosporin A Dihydro Impurity; Cyclosporine EP Impurity B; Ciclosporin EP Impurity B. CAS No. 59865-15-5. Pack Sizes: 25 mg. Product ID: BBF-05757. Molecular formula: C62H113N11O12. Mole weight: 1204.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Dihydro Tofacitinib Citrate | An impurity of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: Tofacitinib Impurity; 5,6-Dihydro CP-690550 citrate; 5,6-Dihydro Tofacitinib citrate. Pack Sizes: 25 mg. Product ID: B2694-342495. Molecular formula: C22H30N6O8. Mole weight: 506.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Esculetin | Esculetin is isolated from the peel of Aesculus hippocastanum L. It can quench the inner fluorescence of bovine serum albumin. Esculetin has various biological and pharmaceutical properties including anti-edema, anti-inflammatory, anti-tumour, hepatoprotective, anti-osteoarthritis and anti-rheumatoid arthritis effects. Uses: Anticoagulant effect; antifungal; antiinflammatory. Group: Pharmaceutical. Alternative Names: 6,7-DIHYDROXY-CHROMEN-2-ONE. CAS No. 305-01-1. Pack Sizes: 10 g. Product ID: NP1136. Molecular formula: C9H6O4. Mole weight: 178.14. Custom synthesis is available. Send your inquiries for more information. | London |
| Fenoprofen sodium salt dihydrate | Fenoprofen sodium salt is a nonsteroidal anti-inflammatory drug used to treat mild to moderate pain, osteoarthritis, or rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: α-Methyl-3-phenoxybenzeneacetic Acid Sodium Salt Dihydrate; (±)-α-Methyl-3-phenoxybenzeneacetic Acid Sodium Salt Dihydrate; Fenoprofen sodium salt hydrate; Benzeneacetic acid, α-methyl-3-phenoxy-, sodium salt, hydrate (1:1:2); Benzeneacetic acid, α-methyl-3-phenoxy-, sodium salt, dihydrate; Benzeneacetic acid, α-methyl-3-phenoxy-, sodium salt, dihydrate, (±)-. CAS No. 66424-46-2. Pack Sizes: 10 g. Product ID: B2692-152391. Molecular formula: C15H13NaO3.2H2O. Mole weight: 300.28. Custom synthesis is available. Send your inquiries for more information. | London |
| Feprazone | Feprazone: A nonsteroidal anti-inflammatory drug (NSAID) utilized in the alleviation of pain and inflammation linked to various conditions like arthritis, menstrual cramps, and musculoskeletal disorders. It operates through the suppression of prostaglandins, biological compounds responsible for the onset of pain and inflammation. Group: Pharmaceutical. CAS No. 30748-29-9. Pack Sizes: 1mg;1g;10g. Product ID: 30748-29-9. Molecular formula: C20H20N2O2. Mole weight: 320.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Flurbiprofen | Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class. It exerts analgesic, anti-inflammatory, and antipyretic effects by reversibly inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. Clinically, it is used to manage pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and postoperative discomfort. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. Alternative Names: 2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid; (±)-Flurbiprofen; 2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic acid; 2-(2-Fluoro-4-biphenyl)propionic acid; 2-(2-Fluoro-4-biphenylyl)propanoic acid; 2-(2-Fluoro-4-biphenylyl)propionic acid; 2-Fluoro-α-methyl-4-biphenylacetic acid; 2-Fluoro-α-methyl-4-diphenylacetic acid; 3-Fluoro-4-phenylhydratropic acid; Adfeed; Ansaid; Antadys; BTS 18322; Cebutid; dl-2-(2-Fluoro-4-biphenylyl)propionic acid; dl-Flurbiprofen; Flugalin; Flurbifen; Fluribiprofen; Fluroben; Flurofen; FP 70; FP-A; Froben; rac-Flurbiprofen; Racemic flurbiprofen; Stayban; Synalgo; U 27182; Urbifen; Zepolas. CAS No. 5104-49-4. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04023. Molecular formula: C15H13FO2. Mole weight: 244.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Garbanzol | Garbanzol, a revolutionary therapeutic agent with mighty anti-inflammatory properties, proffers a potential cure for a myriad of inflammatory ailments. Counted among them are rheumatoid arthritis, psoriasis, and inflammatory bowel disease. By constraining vital enzymes linked with inflammation, Garbanzol governs the synthesis of pro-inflammatory cytokines. Encouragingly, clinical trials demonstrate an encouraging safety profile, and an exceptional tolerance capacity. Group: Pharmaceutical. Alternative Names: (2R-trans)-3,4',7-Trihydroxyflavanone. CAS No. 1226-22-8. Pack Sizes: 1 mg. Product ID: NP2448. Molecular formula: C15H12O5. Mole weight: 272.25. Custom synthesis is available. Send your inquiries for more information. | London |
| GDC-0853 | GDC-0853 is a Bruton's tyrosine kinase (BTK) inhibitor originated by Genentech. GDC-0853 can inhibit the activity of BTK and prevent the activation of the B-cell antigen receptor (BCR) signaling pathway. This leads to the inhibition of the growth of malignant B-cells that overexpress BTK. Phase III clinical trials for the treatment of Multiple sclerosis and Phase II clinical trials for the treatment of Chronic urticaria and Systemic lupus erythematosus are on-going. Uses: Rheumatoid arthritis; autoimmune disorders. Group: Pharmaceutical. Alternative Names: Fenebrutinib; RG 7845; RG7845; GDC0853; RG-7845; GDC 0853; (S)-2-(3'-(hydroxymethyl)-1-methyl-5-((5-(2-methyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one. CAS No. 1434048-34-6. Pack Sizes: 100 mg. Product ID: B2693-475436. Molecular formula: C37H44N8O4. Mole weight: 664.81. Custom synthesis is available. Send your inquiries for more information. | London |
| Geclosporin | Geclosporin is an impurity of cycloporine, which is an immunosuppressant used in the treatment of rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, etc. Uses: Immunosuppressant. Group: Pharmaceutical. Alternative Names: Cyclosporin G; Cyclosporine G. CAS No. 74436-00-3. Pack Sizes: 5 mg. Product ID: BBF-05767. Molecular formula: C63H113N11O12. Mole weight: 1216.662. Custom synthesis is available. Send your inquiries for more information. | London |
| Gly-Glu-Gly | Behold Gly-Glu-Gly, a tripeptide showing promising efficacy as a natural anti-inflammatory agent in biomedical contexts. Its potential is grounded in studies that have explored its aptitude for mitigating oxidative stress and inflammation in numerous diseases including rheumatoid arthritis, asthma, and cerebral ischemia/reperfusion injury. The full extent of its therapeutic potential, however, remains a topic of ongoing research and investigation. Group: Pharmaceutical. Alternative Names: Gly-Glu-Gly; H-GLY-GLU-GLY-OH; glycylglutamylglycine. CAS No. 50997-16-5. Pack Sizes: 5 mg. Product ID: BAT-006210. Molecular formula: C9H15N3O6. Mole weight: 261.23. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK2982772 | GSK2982772, with potential effect to treat inflammatory diseases, potently binds to RIP1 with exquisite kinase specificity. In phase 2a clinical studies for psoriasis, rheumatoid arthritis, and ulcerative colitis. Group: Pharmaceutical. Alternative Names: GSK2982772; GSK 2982772; GSK-2982772; 5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide. CAS No. 1622848-92-3. Pack Sizes: 100 mg. Product ID: B0084-007719. Molecular formula: C20H19N5O3. Mole weight: 377.4. Custom synthesis is available. Send your inquiries for more information. | London |
| H-Phe(4-Ac)-OH HCl | H-Phe(4-Ac)-OH HCl, an essential chemical for a wide range of pharmaceutical and peptide synthesis, boasts exceptional adequacy as a constituent for drug production. This product serves as a key reagent as well as a fundamental building block in the synthesis of peptide-based medications. Medical professionals and researchers commonly employ H-Phe(4-Ac)-OH HCl as an effective measure in the treatment of chronic pain and inflammation arising due to a multitude of conditions, including but not limited to osteoarthritis and rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: 4-Acetyl-L-phenylalanine Hydrochloride; 4-Acetylphenylalanine hydrochloride; (S)-3-(4-Acetylphenyl)-2-aminopropanoic acid HCl; p-Acetylphenylalanine hydrochloride. CAS No. 20299-31-4. Pack Sizes: 2.5 g. Product ID: BAT-008576. Molecular formula: C11H14ClNO3. Mole weight: 243.68. Custom synthesis is available. Send your inquiries for more information. | London |
| Icosanamide | Icosanamide, a derivative of fatty acid, displays promise as a therapeutic agent for diverse inflammatory ailments. With its impressive anti-inflammatory attributes, the compound has garnered attention for handling autoimmune diseases and treating conditions such as rheumatoid arthritis. Its efficacy is well-documented in several clinical studies. Group: Pharmaceutical. Alternative Names: Eicosanamide; Arachamide. CAS No. 51360-63-5. Pack Sizes: 100 mg. Product ID: B0001-274275. Molecular formula: C20H41NO. Mole weight: 311.554. Custom synthesis is available. Send your inquiries for more information. | London |
| IRAK4-IN-3 | IRAK4-IN-3 is a compound with exceptional potency and selectivity against interleukin-1 receptor-associated kinase 4 (IRAK4), an inflammation-linked kinase. This compound has displayed tremendous promise in the treatment of autoimmune conditions, including rheumatoid arthritis and systemic lupus erythematosus. As such, it represents a significant advance in the field of molecular therapeutics targeting inflammatory disorders. Group: Pharmaceutical. Alternative Names: IRAK4-IN-3 is an IRAK4 inhibitor. CAS No. 2196204-23-4. Pack Sizes: 50 mg. Product ID: B2693-336218. Molecular formula: C21H31N5O2. Mole weight: 385.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Jinflexin A | Jinflexin A is a remarkable and potent pharmacological natural compound, finding extensive application for studying various ailments such as rheumatoid arthritis, osteoarthritis and diverse inflammatory joint disorders. This multifaceted natural compound exerts its mechanism of action via the proficient inhibition of pro-inflammatory cytokine production. Group: Pharmaceutical. CAS No. 2055155-75-2. Pack Sizes: 1 mg. Product ID: NP5010. Molecular formula: C19H22O3. Mole weight: 298.382. Custom synthesis is available. Send your inquiries for more information. | London |
| Lacto-N-neohexaose | Lacto-N-neohexaose is a cutting-edge compound with remarkable anti-inflammatory powers, aiding in the research of autoimmune disorders, most notably rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: D-Glucose, O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-[O-β-D-galactopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→6)]-O-β-D-galactopyranosyl-(1→4)-; O-β-D-Galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-[O-β-D-galactopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→6)]-O-β-D-galactopyranosyl-(1→4)-D-glucose. CAS No. 64003-52-7. Pack Sizes: 5 mg. Product ID: B1370-003254. Molecular formula: C40H68N2O31. Mole weight: 1072.96. Custom synthesis is available. Send your inquiries for more information. | London |
| Lobenzarit disodium | Lobenzarit disodium is an immunomodulator commonly used for the treatment of arthritis. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. Alternative Names: Lobenzarit sodium; Lobenzarit disodium salt; Disodium 4-chloro-2,2'-iminobenzoate; disodium 2-(2-carboxylatoanilino)-4-chlorobenzoate. CAS No. 64808-48-6. Pack Sizes: 100 mg. Product ID: B0084-074412. Molecular formula: C14H8ClNNa2O4. Mole weight: 335.651. Custom synthesis is available. Send your inquiries for more information. | London |
| Madecassoside | Madecassoside is a neuroprotective and may be useful in reducing the damage caused by stroke. Madecassoside also has whitening effect, thus can be used in cosmetic material. Uses: Anti-arthritis. Group: Pharmaceutical. Alternative Names: 6-Deoxy-a-L-mannopyranosyl-1-4-b-D-glucopyranosyl-1-6-b-D-glucopyranosyl-(2a,3b,4a,6b)-2,3,6,23-tetrahydroxyurs-12-en-28-oate. CAS No. 34540-22-2. Pack Sizes: 100 mg. Product ID: NP7013. Molecular formula: C48H78O20. Mole weight: 975.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Methotrexate disodium | Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia). Group: Pharmaceutical. Alternative Names: Amethopterin Sodium; Methotrexate Lederle; Metoart; Metotrexato Lederle; Sodium Methotrexate; N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid Disodium Salt; 4-amino-n(sup10)-methyl pteroyl glutamic acid disodium salt; amethopterin sodium. CAS No. 7413-34-5. Pack Sizes: 1 g. Product ID: B1335-076226. Molecular formula: C20H20N8Na2O5. Mole weight: 498.4. Custom synthesis is available. Send your inquiries for more information. | London |
| N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetamide | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Group: Pharmaceutical. Alternative Names: N-[[4-(5-methyl-3-phenylisoxazol-4-yl)phenyl]sulfonyl]acetamide. CAS No. 198471-06-6. Pack Sizes: 20 mg. Product ID: B2694-484462. Molecular formula: C18H16N2O4S. Mole weight: 356.4. Custom synthesis is available. Send your inquiries for more information. | London |
| N6-(cis-hydroxyisopentenyl)adenosine | N6-(cis-hydroxyisopentenyl)adenosine is a remarkable biochemical compound, used for studying an array of ailments and circumstances including breast and lung cancer. Swiftly, it embraces anti-inflammatory traits thus used for studying diseases of inflammation, particularly the notorious rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: Adenosine, N-(4-hydroxy-3-methyl-2-butenyl)-, (Z); 9-beta-D-ribofuranosyl-cis-zeatin; (2R,3R,4S,5R)-2-(6-(((Z)-4-Hydroxy-3-methylbut-2-en-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; cis-Zeatin riboside; 9-ribosyl-cis-zeatin; 9-ribosylzeatin. CAS No. 15896-46-5. Pack Sizes: 5 mg. Product ID: B1370-001245. Molecular formula: C15H21N5O5. Mole weight: 351.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Naproxen | (S)-Naproxen is a non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 μM and 2.0-28.4 μM, respectively. It is an anti-inflammatory agent with analgesic and antipyretic activities, which is commonly used for the treatment of rheumatoid arthritis and gout. Uses: The treatment of rheumatoid arthritis and gout. Group: Pharmaceutical. Alternative Names: (S)-6-Methoxy-α-methyl-2-naphthaleneacetic Acid; po-Naproxen; Aproxen; Bonyl; CG 3117; CG3117; CG-3117; Diocodal; Dysmenalgit; Equiproxen; Floginax; Laraflex; Laser; MNPA; Naixan; Napren; Naprium; Naprius; Naprosyn; Naprosyne; Naproxen; Naprux; Naxen; Nycopren; Panoxen; Prexan; Proxen; Proxine; RS 3540; RS3540; RS-3540; Reuxen; Veradol; Xenar; Xenar-CR; d-2-(6-Methoxy-2-naphthyl)propionic Acid; d-Naproxen. CAS No. 22204-53-1. Pack Sizes: 50 g. Product ID: NP2658. Molecular formula: C14H14O3. Mole weight: 230.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Neokestose | Neokestose is an innovative biomedical substance employed for studying diverse pathological conditions like inflammatory bowel disease, rheumatoid arthritis and allergic disorders. Group: Pharmaceutical. Alternative Names: Neo-Kestose; 6G-Kestose; 6G-Kestotriose; 2-O-[6-O-(β-D-Fructofuranosyl)-α-D-glucopyranosyl]-β-D-fructofuranose; O-b-D-Fructofuranosyl-(1,6)-b-D-fructofuranosyl-a-D-glucopyranoside. CAS No. 3688-75-3. Pack Sizes: 1 mg. Product ID: B1370-003473. Molecular formula: C18H32O16. Mole weight: 504.44. Custom synthesis is available. Send your inquiries for more information. | London |
| N,N-diethyl-2-((6-methylpyridin-2-yl)methylene)hydrazinecarbothioamide | N,N-diethyl-2-((6-methylpyridin-2-yl)methylene)hydrazinecarbothioamide, a chemically-complex compound, is gaining recognition in biomedicine as a viable drug candidate for treating a range of ailments. Notably, research suggests that it possesses considerable anti-inflammatory, analgesic, and antioxidant activity that could hold promise in combatting conditions such as arthritis and other inflammatory disorders. Nevertheless, comprehensive studies are necessary to ascertain its optimal therapeutic capacity. Group: Pharmaceutical. Alternative Names: Hydrazinecarbothioamide, N,N-diethyl-2-[(6-methyl-2-pyridinyl)methylene]-. CAS No. 210700-64-4. Pack Sizes: 10 mg. Product ID: B0001-284864. Molecular formula: C12H18N4S. Mole weight: 250.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Noreugenin | Noreugenin is an organic extract illuminated by its profound anti-inflammatory attributes, aiding in studying ailments spanning arthritis, asthma and inflammatory bowel disorder. Group: Pharmaceutical. Alternative Names: 5,7-Dihydroxy-2-methyl-4H-chromen-4-one; 5,7-Dihydroxy-2-methylchromone. CAS No. 1013-69-0. Pack Sizes: 25 mg. Product ID: NP5182. Molecular formula: C10H8O4. Mole weight: 192.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Norisoboldine | Norisoboldine might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. Group: Pharmaceutical. Alternative Names: norisoboldine; (+)-Laurelliptine; (+)-N-Norisoboldine; (6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-4H-dibenzo[de,g]quinoline-1,9-diol; (S)-(+)-Laurelliptine. CAS No. 23599-69-1. Pack Sizes: 20 mg. Product ID: B2703-464432. Molecular formula: C18H19NO4. Mole weight: 313.35. Custom synthesis is available. Send your inquiries for more information. | London |
| ONO-4059 (hydrochloride) | ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model. Group: Pharmaceutical. Alternative Names: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one hydrochloride; ONO-4059 HCl; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. CAS No. 1439901-97-9. Pack Sizes: 50 mg. Product ID: B0084-474577. Molecular formula: C25H23ClN6O3. Mole weight: 490.95. Custom synthesis is available. Send your inquiries for more information. | London |
| oxypeucedanin | Oxypeucedanin, a derivative of coumarin of natural origins, has exhibited encouraging outcomes in the management of diverse medical conditions. Its potential as a cure for inflammatory diseases like arthritis is attributed to its anti-inflammatory characteristics. Moreover, oxypeucedanin has demonstrated anticancer features, particularly in the care for breast cancer. Its capacity for inducing apoptosis and hindering tumor growth elevates it as a propitious therapeutic alternative. Group: Pharmaceutical. Alternative Names: Oxypeucedarin; 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((3,3-dimethyloxiranyl)methoxy)-; 4-[(3,3-dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g]chromen-7-one; 5-[(3,3-dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g]chromen-7-one. CAS No. 737-52-0. Pack Sizes: 50 mg. Product ID: B2703-097772. Molecular formula: C16H14O5. Mole weight: 286.28. Custom synthesis is available. Send your inquiries for more information. | London |
| Peficitinib | Peficitinib is a potent JAK inhibitor with IC50 values of 3.9, 5.0, 0.71 and 4.8 nM for JAK1, JAK2, JAK3 and TYK2 enzyme activities, respectively. It inhibits the IL-2-induced proliferation of human T cells with IC50 value of 18 nM. Moreover, peficitinib is 14-fold more potent against JAK1/3 than JAK2/2 on the basis of EPO-induced proliferation of human leukemia cells. Peficitinib has been used for the treatment of psoriasis and rheumatoid arthritis. Uses: Inhibited jak1, jak2, jak3 and tyk2 enzyme activities with ic50 values of 3.9, 5.0, 0.71 and 4.8 nm, respectively; inhibited the il-2-induced proliferation of human t cells with an ic50 value of 18 nm. Group: Pharmaceutical. Alternative Names: ASP015K; ASP-015K; 4-[[(1R,3S)-5-hydroxy-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide. CAS No. 944118-01-8. Pack Sizes: 25 mg. Product ID: B0084-462759. Molecular formula: C18H22N4O2. Mole weight: 326.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Ponesimod | Ponesimod is an orally active and selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator that acts as a functional antagonist. It has potential immunomodulating activity. It may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. It is also an experimental drug for the treatment of multiple sclerosis (MS) and psoriasis. It protects against lymphocyte-mediated tissue inflammation. It activated S1P(1)-mediated signal transduction with high potency (EC(50) of 5.7 nM) and selectivity in vitro. It prevented edema formation, inflammatory cell accumulation and cytokine release in the skin of mice with delayed-type hypersensitivity. It also prevented the increase in paw volume and joint inflammation in rats with adjuvant-induced arthritis. It reduces both the amount of circulating peripheral lymphocytes and the infiltration of lymphocytes into target tissues by preventing egress of lymphocytes. It was developed by Actelion. It is in Clinical stage three. Uses: Ponesimod acts as a functional antagonist. it has potential immunomodulating activity. it may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. it is also an experimental drug for the treatment of multiple sclerosis (ms) and psoriasis. Group: Pharmaceutical. Alternative Names: ACT-128800; ACT 128800; ACT128800; Ponvory; (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolyl | London |
| (S)-(+)-2-methylbutyl p-[(p-methoxybenzylidene)amino]cinnamate | (S)-(+)-2-methylbutyl p-[(p-methoxybenzylidene)amino]cinnamate, an active pharmaceutical intermediate, is a vital component in the pharmaceutical industry for synthesizing medications that alleviate pain and inflammation. Such disorders include osteoarthritis and arthritis, among others. Its significant role in medicinal chemistry, as a proficient synthesis intermediate, cannot be emphasized enough. Group: Pharmaceutical. Alternative Names: (+)-2-METHYLBUTYL-P[(P-METHOXYBENZYLIDENE)AMINO]CINNAMATE; ACTIVE-AMYL P-ANISALAMINOCINNAMATE; ACT-AMYL P-ANISALAMINOCINNAMATE; (S)-(+)-2-METHYLBUTYL P-[(P-METHOXYBENZYLIDENE)AMINO]CINNAMATE; (+)-2-methylbutyl-4-methoxybenzilidine-4'-aminocinnamate; (+)-2-met. CAS No. 24140-30-5. Pack Sizes: 1 g. Product ID: B2699-238711. Molecular formula: C22H25NO3. Mole weight: 351.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Sappanchalcone | Sappanchalcone is a natural flavonoid extracted from Caesalpinia sappan. It exhibits cytoprotective activity and anti-inflammatory effects, which can reduce clinical arthritis. Sappanchalcone is also a xanthine oxidase inhibitor. Uses: Cytoprotective, anti-inflammatory. Group: Pharmaceutical. Alternative Names: (2E)-3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-Methoxyphenyl)-2-propen-1-one; 3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-Methoxyphenyl)prop-2-en-1-one. CAS No. 94344-54-4. Pack Sizes: 5 mg. Product ID: NP0934. Molecular formula: C16H14O5. Mole weight: 286.3. Custom synthesis is available. Send your inquiries for more information. | London |
| SD-06 | SD-06 is an inhibitor of p38α (IC50=170 nM). It is developed for the treatment of arthritis. Group: Pharmaceutical. Alternative Names: SD 0006; SD-0006; SD0006; SD-06; SD-06; SD-06. CAS No. 271576-80-8. Pack Sizes: 500 mg. Product ID: B2693-454431. Molecular formula: C20H20ClN5O2. Mole weight: 397.86. Custom synthesis is available. Send your inquiries for more information. | London |
| SINOACUTINE | Sinoacutine, a natural alkaloid sourced from flora, boasts analgesic and anti-inflammatory properties backed by clinical research. The compound's potential in treating inflammatory diseases, including rheumatoid arthritis, has been subject to investigations. Sinoacutine's efficacy in regulating immune responses is attributable to its ability to obstruct the release of inflammatory cytokines, rendering it a viable candidate in the development of novel anti-inflammatory agents. Group: Pharmaceutical. Alternative Names: Sinoacutin. CAS No. 4090-18-0. Pack Sizes: 5 mg. Product ID: NP0371. Molecular formula: C19H21NO4. Mole weight: 327.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Sodium 3-hydroxybenzenesulfonate | Sodium 3-hydroxybenzenesulfonate, an organic chemical commonly employed in medicinal production and synthetic processes, exerts potent anti-inflammatory and analgesic actions. Such biochemical interventions are found efficacious in countering a panoply of afflictions including pain, fever, and inflammation symptomatic of arthritis and rheumatoid disorders. Group: Pharmaceutical. Alternative Names: sodium 3-hydroxybenzenesulfonate; Sodium m-phenolsulfonate. CAS No. 14278-60-5. Pack Sizes: 5 g. Product ID: B2699-067853. Molecular formula: C6H5NaO4S. Mole weight: 196.16. Custom synthesis is available. Send your inquiries for more information. | London |
| T-5224 | T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II human clinical trials. T-5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation. Accumulating evidence supports that AP-1 plays an important role in several severe disorders including cancer, fibrosis, and organ injury, as well as inflammatory disorders such as asthma, psoriasis, and rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: T5224; T 5224. CAS No. 530141-72-1. Pack Sizes: 100 mg. Product ID: B1370-462792. Molecular formula: C29H27NO8. Mole weight: 517.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Tetracosanedioic acid mono-tert-butyl ester | Tetracosanedioic acid mono-tert-butyl ester, a chemical entity prevalently utilized in the biomedical domain, confers anti-inflammatory effect on account of certain properties it bears. This compound constrains the manufacturing of pro-inflammatory cytokines besides mitigating the inflammatory response, in an array of animal models. Subsequently, it showcases prospective therapeutic ability for countering prevalent disorders such as atherosclerosis and rheumatoid arthritis, thereby paving way for effective medical management. Group: Pharmaceutical. Pack Sizes: 100 mg. Product ID: B0001-138722. Molecular formula: C28H54O4. Mole weight: 454.73. Custom synthesis is available. Send your inquiries for more information. | London |
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