Apoptosis Suppliers UK
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Product | Description | |
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Albomitomycin C Quick enquiry Where to buy Suppliers range | Albomitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells. Group: Pharmaceuticals. Alternative Names: (1S,2S,4S,5R,6S,6aR,10aS,11S)-8-Amino-6-[[(aminocarbonyl)oxy]methyl]-2,3,6,6a-tetrahydro-5-methoxy-9-methyl-1,2,5-metheno-1H,5H-imidazo[2,1-i]indole-7,10-dione; Antibiotic CX 1; [1S-(1α, 2α, 4β, 5β, 6α, 6aα, 10aR*, 11R*)]-8-amino-6-[[(aminocarbonyl) oxy]methyl]-2,3,6,6a-tetrahydro-5-methoxy-9-methyl-1,2,5-Metheno-1H,5H-imidazo[2,1-i]indole-7,10-dione. CAS No. 111750-67-5. Pack Sizes: 1mg; 1g; 10g. Product ID: 111750-67-5. Custom synthesis is available. Send your inquiries for more information. | London |
Aspulvinone O Quick enquiry Where to buy Suppliers range | Aspulvinone O is a fungal metabolite originally isolated from P. variotti and has antioxidant and anticancer activities. It inhibits aspartate transaminase 1 (GOT1, Kd = 3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM). Aspulvinone O (2.5 and 5 mg/kg) reduces tumor growth in an SW1990 mouse xenograft model because it reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Group: Pharmaceuticals. Alternative Names: 914071-54-8; 3-[2,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-4-hydroxy-5-[[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]methylene]-2(5H)-furanone(5Z)-3-[2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-4-hydroxy-5-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methylidene]furan-2-one; Aspulvinone OMEGxm0_000073. CAS No. 914071-54-8. Pack Sizes: 1mg; 1g; 10g. Product ID: 914071-54-8. Custom synthesis is available. Send your inquiries for more information. | London |
BIOGLYCOGEN Quick enquiry Where to buy Suppliers range | Consists of a-1,4ï¼1,6 linkages of glucose. It provides an aging care effect. It has a production of ATP, Hyaluronic acid, Ceramide. It provides mprovement of Stratum corneum hydration, average depth of maximum wrinkle, average area of pores, and an anti-UV effect. Improvement of protein expressions related to antioxidant proteins. Inhibition of apoptosis induced by UV irradiation and suppression of Erythema value. Uses: Hair Care; Sun Care; Skin Care. Group: Personal Care, Cosmetics & Toiletries. Glucose Derivative. Active. Powder. CAS No. 9005-79-2. Product ID: PIM000007713. | DKSH Great Britain |
D-alpha-Tocopherol Succinate Quick enquiry Where to buy Suppliers range | D-alpha-Tocopherol Succinate is the salt form of vitamin E, a class of eight fat-soluble compounds. It was shown to induce apoptosis and inhibit proliferation, and down-regulate the fibroblast growth factor receptor-1 (FGFR1). Vitamin supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceuticals. Alternative Names: Vitamin E succinate; Alpha-Tocopheryl succinate; D-; 4-oxo-4-[[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]butanoic acid. CAS No. 4345-3-3. Pack Sizes: 1mg; 1g; 10g. Product ID: B1961-331652. Custom synthesis is available. Send your inquiries for more information. | London |
Docetaxel Trihydrate Quick enquiry Where to buy Suppliers range | Docetaxel is a cytotoxic agent, which is related to its ability to promote the formation of microtubule bundles and induce sustained mitotic arrest, followed by apoptosis of mitotically arrested cells or permanent mitotic block. Group: Pharmaceuticals. Alternative Names: 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete Benzenepropanoic Acid Deriv.; [2aR-[2aα, 4β, 4aβ, 6β, 9α(αR*, βS*), 11α, 12α, 12aα, 12bα]]-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-4, 6, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-ylester-β-[[(1, 1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic Acid Trihydrate; (αR,βS)-(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylester-β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic Acid Trihydrate; N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel trihydrate; 4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate--water (1/3); Docetaxel (USP) RP56976 (NSC 628503) Trihydrate; RP 56976 (NSC-628503) Trihydrate; RP-56976 (NSC628503) Trihydrate. CAS No. 148408-66-6. Pack Sizes: 1mg; 1g; 10g. Product ID: 148408-66-6. Custom synthesis is available. Send your inquiries for more information. | London |
Edaravone Quick enquiry Where to buy Suppliers range | Edaravone is a novel potent free radical scavenger that reduces reactive oxygen species, inhibites apoptosis, and blocks nonenzymatic peroxidation and lipoxygenase activity. Group: Pharmaceuticals. Alternative Names: Edaravone; MCI-186; MCI 186; MCI186; Radicut; Arone. CAS No. 89-25-8. Pack Sizes: 1mg; 1g; 10g. Product ID: 89-25-8. Custom synthesis is available. Send your inquiries for more information. | London |
Edaravone Trimer Quick enquiry Where to buy Suppliers range | Edaravone Trimer is an impurity of Edaravone. Edaravone is a novel potent free radical scavenger that reduces reactive oxygen species, inhibits apoptosis, and blocks nonenzymatic peroxidation and lipoxygenase activity. Group: Pharmaceuticals. Alternative Names: 5,?5',?5''-trimethyl-2,?2',?2''-triphenyl-[4,?4':4',?4''-Ter-4H-pyrazole]?-3,?3',?3''(2H,?2'H,?2''H)?-trione; 4,4-bis(3-methyl-5-oxo-1-phenyl(2-pyrazolin-4-yl))-3-methyl-1-phenyl-2-pyrazol in-5-one; 2-Phenyl-5-methyl-4,4-bis(2-phenyl-3-oxo-5-methyl-3,4-dihydro-2H-pyrazole-4-yl)-3,4-dihydro-2H-pyrazole-3-one. CAS No. 68195-63-1. Pack Sizes: 1mg; 1g; 10g. Product ID: 68195-63-1. Custom synthesis is available. Send your inquiries for more information. | London |
Glycoursodeoxycholic acid Quick enquiry Where to buy Suppliers range | Glycoursodeoxycholic Acid is a metabolite of Ursodeoxycholic Acid. Ursodeoxycholic Acid is one of metabolites of intestinal bacteria. Ursodeoxycholic Acid shows an effect of apoptosis suppression and reduction in gallstone formation. Group: Pharmaceuticals. Alternative Names: Ursodeoxycholylglycine; GUDCA; Glycine ursodeoxycholic acid; N-(3alpha,7beta-dihydroxy-5beta-cholan-24-oyl)-glycine; N-[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]-glycine. CAS No. 64480-66-6. Pack Sizes: 1mg; 1g; 10g. Product ID: 64480-66-6. Custom synthesis is available. Send your inquiries for more information. | London |
Mitosene Quick enquiry Where to buy Suppliers range | A derived from Mitomycin, which is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cell. Group: Pharmaceuticals. Alternative Names: 3H-Pyrrolo[1,?2-a]?indole. CAS No. 247-67-6. Pack Sizes: 1mg; 1g; 10g. Product ID: 247-67-6. Custom synthesis is available. Send your inquiries for more information. | London |
Olaquindox Quick enquiry Where to buy Suppliers range | Olaquindox, as one of the antimicrobial growth accelerants, is usually used in livestock production to improve feed efficiency. Olaquindox induced apoptosis of HepG2 cells through a caspase-9 dependent mitochondrial pathway. Besides, Olaquindox also induces autophagy in HepG2 cells and that Olaquindox-induced apoptosis can be enhanced by 3-methyladenine. Olaquindox-induced autophagy in HepG2 cells is upregulated by Beclin 1 but downregulated by ROS-dependent JNK. Uses: Antimicrobial growth accelerant. Group: Pharmaceuticals. Alternative Names: N-(2-HYDROXYETHYL)-3-METHYL-2-QUINOXALINECARBOXAMIDE 1,4-DIOXIDE;OLAGUINDOX; OLAQUINDOX;2-(n-(2-hydroxyethyl)karbamoyl)-3-methylchinoxalin-1,4-dioxid; 2-quinoxalinecarboxamide,n-(2-hydroxyethyl)-3-methyl-,1,4-dioxide;bayernox;bayonox; bisergon. CAS No. 23696-28-8. Pack Sizes: 1mg; 1g; 10g. Product ID: 23696-28-8. Custom synthesis is available. Send your inquiries for more information. | London |
Oprozomib Quick enquiry Where to buy Suppliers range | Oprozomibm, also known as ONX 0912 and PR 047, is an orally bioavailable proteasome inhibitor with potential antineoplastic activity. ONX 0912 inhibits the activity of the proteasome, thereby blocking the targeted proteolysis normally performed by the proteasome; this may result in an accumulation of unwanted or misfolded proteins. Disruption of various cell signaling pathways may follow, eventually leading to the induction of apoptosis and inhibition of tumor growth. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquitinated. Group: Pharmaceuticals. Alternative Names: ONX0912; ONX-0912; ONX 0912; PR047; PR-047; PR 047. CAS No. 935888-69-0. Pack Sizes: 1mg; 1g; 10g. Product ID: 935888-69-0. Custom synthesis is available. Send your inquiries for more information. | London |
Tauroursodiol Quick enquiry Where to buy Suppliers range | Tauroursodiol is a bile acid formed in the liver. Tauroursodiol shows an effect of apoptosis suppression and reduction in gallstone formation. Group: Pharmaceuticals. Alternative Names: 9,10-secocholesta-5,7,10-trien-3-ol; 2-{[(3alpha,5beta,7beta,8xi,9xi,14xi)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid; 2-{[(3alpha,5beta,7beta)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid. CAS No. 14605-22-2. Pack Sizes: 1mg; 1g; 10g. Product ID: 14605-22-2. Custom synthesis is available. Send your inquiries for more information. | London |
Topotecan Quick enquiry Where to buy Suppliers range | Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells. Group: Pharmaceuticals. Alternative Names: (S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride;Hycamtin; SKF104864; SKF 104864; SKF-104864. CAS No. 123948-87-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BADC-00328. Custom synthesis is available. Send your inquiries for more information. | London |
Tryptoquivaline D Quick enquiry Where to buy Suppliers range | Tryptoquivaline D is a fungal metabolite originally isolated from Neosartorya siamensis and it has anticancer activity. It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells when used at a concentration of 150 μM. Group: Pharmaceuticals. Alternative Names: Nortryptoquivaline; NSC 292204. CAS No. 60676-56-4. Pack Sizes: 1mg; 1g; 10g. Product ID: 60676-56-4. Custom synthesis is available. Send your inquiries for more information. | London |