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| Product | Description | |
|---|---|---|
| Antagonist G | Antagonist G is a substance P analog, which is a broad spectrum neuropeptide growth factor antagonist and antiproliferative agent. It was developed for the treatment of small cell lung cancer. It could inhibit neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro. It also inhibits growth of SCLC xenografts in mice in vivo. It blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. It activates JNK and stimulates apoptosis. It is an anticancer agent and is resistant to degradation by peptidases. Group: Pharmaceutical. CAS No. 115150-59-9. Pack Sizes: 1 mg. Product ID: BAT-006104. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 5-HT3 antagonist 5 | 5-HT3 antagonist 5 is a 5-HT3 receptor antagonist with anti-depressant activity. Group: Pharmaceutical. CAS No. 901599-43-7. Pack Sizes: 50 mg. Product ID: B1370-186731. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-(4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-5-yl)ethanone | An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. CAS No. 1227626-50-7. Pack Sizes: 100 mg. Product ID: B0176-284898. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2,2'-(2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-4,5-diyl)bis(propan-2-ol) | An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. CAS No. 1418133-29-5. Pack Sizes: 100 mg. Product ID: B0176-284894. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2, 2'-(((3aR, 3a'R, 4S, 4'S, 6R, 6aS, 6'R, 6a'S)-6, 6'-((5-nitro-2-(propylthio)pyrimidine-4, 6-diyl)bis(azanediyl))bis(2, 2-dimethyltetrahydro-3aH-cyclopenta[d][1, 3]dioxole-6, 4-diyl))bis(oxy))diethanol | An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. CAS No. 1882095-50-2. Pack Sizes: 100 mg. Product ID: B0027-284940. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol | 2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is an intermediate in the synthesis of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. CAS No. 150026-75-8. Pack Sizes: 100 mg. Product ID: B0052-208484. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| [2-(Methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide | [2-(Methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide, an innovative pharmaceutical compound, plays a pivotal role in addressing a myriad of diseases by selectively modulating intricate cellular mechanisms. As an effective antagonist of key enzymes involved in the pathogenesis of malignant tumors, it is widely used in antimicrobial drug development. Group: Pharmaceutical. CAS No. 3637-26-1. Pack Sizes: 1 kg. Product ID: B1370-091081. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Propylsulfanyl-pyrimidin-4-ol | An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. CAS No. 54460-95-6. Pack Sizes: 100 mg. Product ID: B0027-284937. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (2R,3R)-2,3-Dihydroxybutanedioate | An impurity of Bepotastine besylate, a histamine H1 receptor antagonist that has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus. Group: Pharmaceutical. CAS No. 210095-58-2. Pack Sizes: 50 g. Product ID: B2694-014533. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Hydroxy agomelatine-[d3] | 3-Hydroxy agomelatine-[d3] is an isotope labelled compound of 3-Hydroxyagomelatine which is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM. Group: Pharmaceutical. CAS No. 1079774-23-4. Pack Sizes: 10 mg. Product ID: BLP-013596. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Chloro-2-propylsulfanyl-pyrimidine | An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. CAS No. 1351990-36-7. Pack Sizes: 100 mg. Product ID: B0027-284938. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(2-Chlorobenzyl)thieno(3,2-C)pyridinium chloride | 5-(2-Chlorobenzyl)thieno(3,2-C)pyridinium chloride is an impurity of Ticlopidine, a reversible P2Y12 receptor antagonist used to decrease the risk of stroke in patients known to have atherosclerosis. Group: Pharmaceutical. CAS No. 53885-64-6. Pack Sizes: 25 mg. Product ID: B1370-469260. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4'-(azidomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Group: Pharmaceutical. CAS No. 152708-24-2. Pack Sizes: 25 mg. Product ID: B2694-376321. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate | An impurity of Prasugrel. Prasugrel is a platelet inhibitor and an irreversible antagonist of P2Y12ADP receptors that prevents the formation of blood clots. It was appoved for the treatment of acute coronary syndrome (ACS), and some cardiovascular diseasess in combination with Aspirin. Group: Pharmaceutical. CAS No. 1373350-61-8. Pack Sizes: 20 mg. Product ID: B0219-007244. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-methoxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate | An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. CAS No. 1040405-56-8. Pack Sizes: 100 mg. Product ID: B0176-284897. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Keto Fulvestrant | 6-Keto Fulvestrant is an impurity of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B2694-471908. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Deschloro-8-bromo-N-methyl Desloratadine | 8-Deschloro-8-bromo-N-methyl Desloratadine is one of Loratadine derivatives. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Group: Pharmaceutical. CAS No. 130642-57-8. Pack Sizes: 25 mg. Product ID: B1370-118732. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A 1120 | A 1120 is a retinol-binding protein 4 (RBP4) antagonist (Ki = 8.3 nM) that can reduce serum RBP4 and retinol, and displaces transthyretin (TTR) from RBP4-TTR complexes. Group: Pharmaceutical. CAS No. 1152782-19-8. Pack Sizes: 100 mg. Product ID: B1370-271974. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A 71915 | A 71915 is a highly potent and competitive natriuretic peptide receptor A (NPRA) antagonist (pKi = 9.18). Group: Pharmaceutical. CAS No. 132956-87-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015128. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A 779 | A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor) (IC50 = 0.3 nM) with no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. Group: Pharmaceutical. CAS No. 159432-28-7. Pack Sizes: 10 mg. Product ID: BAT-006218. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A 779 TFA | A 779 TFA is a potent angiotensin (1-7) receptor antagonist. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016355. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AB928 | AB928 is a dual antagonist of the A2aR and A2bR adenosine receptors with Kb of 1.5 and 2.0 nM, respectively. It potently blocks the immunosuppressive effects of high adenosine concentrations in the tumor microenvironment. Group: Pharmaceutical. CAS No. 2239273-34-6. Pack Sizes: 50 mg. Product ID: B2693-334167. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Group: Pharmaceutical. CAS No. 183552-38-7. Pack Sizes: 10 mg. Product ID: BAT-006166. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ABT 263-[d8] | ABT 263-[d8] is a labelled ABT 263. ABT 263, also named Navitoclax, is an orally active, synthetic small molecule and an antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. Group: Pharmaceutical. CAS No. 1217620-38-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003186. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC 187 | AC 187 is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo. Group: Pharmaceutical. CAS No. 151804-77-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-010348. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC 187 acetate | AC 187 acetate is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels, and increases food intake in vivo. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016307. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2, (Disulfide bond) | Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2 is a full competitive MCH-1 receptor antagonist and has no agonist effect on human MCH-1 receptor even at micromolar concentrations (Kb = 3.6 nM). Group: Pharmaceutical. CAS No. 353487-64-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015327. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-D-phenylglycinol | Amino acid antagonist. Group: Pharmaceutical. CAS No. 78761-26-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-002629. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acebutolol-[d5] | Acebutolol-[d5] is the labelled analogue of Acebutolol, which is a β-adrenergic receptor antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. Group: Pharmaceutical. CAS No. 1189500-68-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-013703. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acenocoumarol-[d4] | Acenocoumarol-[d4] is a labelled Acenocoumarol. Acenocoumarol, a derivative of coumarin, is an anticoagulant and a Vitamin K antagonist. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003197. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acenocoumarol-[d5] | Acenocoumarol-[d5] is a labelled Acenocoumarol. Acenocoumarol, a derivative of coumarin, is an anticoagulant and a Vitamin K antagonist. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003198. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acepromazine-[d6] | Acepromazine-[d6] is an isotope compound of Acepromazine. Acetylpromazine is a phenothiazine derivative. It has depressant effect on the central nervous system and is used in the treatment of psychoses. It is now almost exclusively used on animals as a sedative and antiemetic. It is used primarily as a chemical restraint in hyperactive or fractious animals. It acts as a dopamine receptor antagonist in the central nervous system, thus causing sedation, muscular relaxation and a reduction in spontaneous activity. It acts as an antagonist on different postsysnaptic receptors - on dopaminergic receptors, on serotonergic receptors, on histaminergic receptors and so on. Group: Pharmaceutical. CAS No. 1173147-97-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003199. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-Amylin (8-37) (human) | Acetyl-Amylin (8-37) (human) is a most effective amylin antagonist, but its ability to block CGRP inhibition is limited. It completely reverses the inhibitory effect of IAPP on 14C-glycogen accumulation in vitro. Group: Pharmaceutical. CAS No. 178603-79-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015123. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetylaszonalenin | Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes. It acts as an antagonist of neurokinin-1 (NK1) receptor. Group: Pharmaceutical. CAS No. 42230-55-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-04519. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-(D-Arg2)-GRF (1-29) amide (human) acetate | Acetyl-(D-Arg2)-GRF (1-29) amide (human) is a GRF antagonist. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-087458. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Hexapeptide-1 | Acetyl Hexapeptide-1, also known as Melitane, is a biomimetic peptide antagonist of the α-MSH (α-Melanocyte-Stimulating Hormone). It stimulates tyrosinase activity, melanin synthesis and melanocyte dendricity, and protects DNA damage caused by UV exposure. Group: Pharmaceutical. CAS No. 448944-47-6. Pack Sizes: 5 mg. Product ID: BAT-006234. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Hexapeptide-38 | Acetyl hexapeptide 38, also known as breast enhancement peptide, is a peroxisome proliferator-activated receptor-γ coactivator 1α antagonist for cellulite therapy. Acetyl Hexapeptide-38 stimulates peroxisome proliferator-activated receptor Gamma coactivator 1a(PGC-1a) expression and increases fatty tissue volume in specific areas. Group: Pharmaceutical. CAS No. 1400634-44-7. Pack Sizes: 1 g. Product ID: BAT-010077. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aclarubicin A | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Group: Pharmaceutical. CAS No. 57576-44-0. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-00542. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aclarubicin hydrochloride | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Group: Pharmaceutical. CAS No. 75443-99-1. Pack Sizes: 5 mg. Product ID: BBF-04081. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aclidinium Bromide-[d5] | Aclidinium Bromide-[d5] is a labelled analogue of Aclidinium Bromide. Aclidinium Bromide is a long-acting muscarinic antagonist (LAMA) used for the treatment of chronic obstructive pulmonary disease (COPD). Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003529. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acrivastine-[d7] | Acrivastine-[d7] is a labelled Acrivastine. Acrivastine, also known as BW825C, is an antihistamine with peripheral H1-antagonist potency equal to that of triprolidine for the treatment of allergic rhinitis. Group: Pharmaceutical. CAS No. 172165-56-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003217. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-RYYRIK-NH2 | Ac-RYYRIK-NH may provide a promising starting point for in vivo tests for antagonism of the action of noc/OFQ and for the further development of highly active and specific antagonists. Group: Pharmaceutical. CAS No. 200959-48-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-010804. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-RYYRIK-NH2 acetate | Ac-RYYRIK-NH2 acetate is a potent and partial agonist on ORL1 transfected in CHO cells (Kd = 1.5 nM). Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain. Group: Pharmaceutical. CAS No. 2863659-08-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016380. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ACTH 11-24 | ACTH(11-24) is a fragment of the adrenocorticotropic hormone (ACTH) and an antagonist of the adrenocorticotropic hormone (ACTH) receptor that induces cortisol release. Group: Pharmaceutical. CAS No. 4237-93-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-010422. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ACV 1 | ACV 1 has been found to be a neuronal nicotinic receptor antagonist and could probably alleviate neuropathic pain. Group: Pharmaceutical. CAS No. 740980-24-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-010312. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AF 353 | AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. It is a highly potent inhibitor of α,β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels. It also blocks human P2X2/3 channel function with marginally reduced potency (pIC50 = 7.3). It significantly reduces this parameter in both groups. It also reduces the inter-contractile interval in control but not in SCI rats. Group: Pharmaceutical. CAS No. 865305-30-2. Pack Sizes: 25 mg. Product ID: B2693-459983. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afacifenacin Impurities | Afacifenacin Impurities hold paramount importance in the biomedical sphere, serving as keystones for quality assurance in afacifenacin development. These elements meticulously evaluate purity, safety, and effectiveness, underpinning the therapeutic crafting of a muscarinic receptor antagonist crucial for managing overactive bladder syndrome, thereby optimizing patient outcomes through rigorous assessment. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afimoxifene | Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia. Uses: Estrogen antagonists. Group: Pharmaceutical. CAS No. 68392-35-8. Pack Sizes: 100 mg. Product ID: B1370-351000. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agomelatine | Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Group: Pharmaceutical. CAS No. 138112-76-2. Pack Sizes: 20 g. Product ID: NP3699. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agomelatine-[d3] | Agomelatine-[d3] is the labelled analogue of Agomelatin, which is a melatoninergic agonist and selective 5-HT2C receptor antagonist. It is used as an atypical antidepressant in the treatment of major depressive disorder. Group: Pharmaceutical. CAS No. 1079389-38-0. Pack Sizes: 5 mg. Product ID: BLP-009578. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agouti-related Protein (AGRP) (25-82), human | Agouti-related protein (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It acts as a melanocortin receptor antagonist that exerts a central inhibitory action on the Hypothalamic-Pituitary-Thyroid (HPT) Axis. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-006143. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Alfuzosin Impurities | Alfuzosin Impurities, utilized in biomedical research, are critical for evaluating the safety and efficacy of the alpha-adrenergic antagonist, Alfuzosin, used in treating benign prostatic hyperplasia. These impurities assist in ensuring drug purity and highlighting potential adverse effects, thereby playing a vital role in quality control and pharmacological studies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Alizapride hydrochloride | Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Group: Pharmaceutical. CAS No. 59338-87-3. Pack Sizes: 200 mg. Product ID: B0084-095175. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Almorexant | Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively. Uses: For research used only. Group: Pharmaceutical. CAS No. 871224-64-5. Pack Sizes: 10 mg. Product ID: B0084-078689. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Altiratinib | Altiratinib, also known as DCC-270, DP-5164, is an oral, selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. DCC-2701 effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Importantly, DCC-2701's anti-proliferative activity was dependent on c-MET activation induced by stromal human fibroblasts and to a lesser extent exogenous HGF. DCC-2701 may be superior to HGF antagonists that are in clinical trials and that pTyr(1349) levels might be a good indicator of c-MET activation and likely response to targeted therapy as a result of signals from the microenvironment. Group: Pharmaceutical. CAS No. 1345847-93-9. Pack Sizes: 50 mg. Product ID: B2693-463181. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AM095 | AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Group: Pharmaceutical. CAS No. 1228690-36-5. Pack Sizes: 1 g. Product ID: B2693-474408. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AM095 sodium | AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Group: Pharmaceutical. CAS No. 1345614-59-6. Pack Sizes: 1 g. Product ID: B2693-465372. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ambrisentan | Ambrisentan, a highly selective antagonist of the endothelin-1 type A receptor with IC50 of 18 nM, is indicated for the treatment of pulmonary arterial hypertension (PAH). Uses: Antihypertensive agents. Group: Pharmaceutical. CAS No. 177036-94-1. Pack Sizes: 50 mg. Product ID: NP3038. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AMD-070 hydrochloride | AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay. Group: Pharmaceutical. CAS No. 880549-30-4. Pack Sizes: 250 mg. Product ID: B2693-463668. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Amisulpride Impurity B | An impurity of Amisulpride, a dopamine D2 receptor antagonist used for the treatment of acute and chronic schizophrenia. Group: Pharmaceutical. CAS No. 148516-54-5. Pack Sizes: 100 mg. Product ID: B2694-466488. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Amisulpride N-oxide | An impurity of Amisulpride, a dopamine D2 receptor antagonist used for the treatment of acute and chronic schizophrenia. Group: Pharmaceutical. CAS No. 71676-01-2. Pack Sizes: 25 mg. Product ID: B2694-466479. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Amprolium hydrochloride | Amprolium chloride is a thiamin antagonist, which prevents carbohydrate synthesis by blocking thiamine uptake. Uses: Coccidiostats. Group: Pharmaceutical. CAS No. 137-88-2. Pack Sizes: 200 g. Product ID: NP2653. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Antide | Antide is a GnRH and LH-RH antagonist that displays potent anti-ovulatory and weak histamine release activity. Uses: Hormone antagonists. Group: Pharmaceutical. CAS No. 112568-12-4. Pack Sizes: 5 mg. Product ID: BAT-010778. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Apalutamide | Apalutamide is a potent and competitive androgen receptor (AR) antagonist with potential antineoplastic activity. It binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. Group: Pharmaceutical. CAS No. 956104-40-8. Pack Sizes: 100 mg. Product ID: B0084-462663. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aprepitant | Aprepitant is a specific NK-1R antagonist, used as an antiemetic agent. Group: Pharmaceutical. CAS No. 170729-80-3. Pack Sizes: 1 g. Product ID: B2692-461949. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aripiprazole-[d8] | Aripiprazole-[d8] is the labelled analogue of Aripiprazole. Aripiprazole, a dihydroquinolinone derivative, is an antagonist of Dopamine-2 receptor and a partial agonist of 5-HT1A receptor. It could be used as an atypical antipsychotic agent. Uses: An isotopic labelled form of aripiprazole which is an antagonist of dopamine-2 receptor and a partial agonist of 5-ht1a receptor that could be used as an antipsychotic agent. Group: Pharmaceutical. CAS No. 1089115-06-9. Pack Sizes: 10 mg. Product ID: BLP-011791. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aripiprazole lauroxil | Aripiprazole lauroxil is a Dopamine D2 receptor agonist, Serotonin 1A receptor agonist and ISerotonin 2A receptor antagonist under the development of Alkermes plc. Aripiprazole lauroxil is applicated as long-acting injectable atypical antipsychotic for the treatment of schizophrenia. It is an N-acyloxymethyl prodrug of aripiprazole. Uses: Schizophrenia. Group: Pharmaceutical. CAS No. 1259305-29-7. Pack Sizes: 100 mg. Product ID: B2693-475236. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Asenapine maleate | Asenapine Maleate is a 5-HT receptor antagonist used for the treatment of acute schizophrenia and bipolar mania. It is a second-generation (atypical) antipsychotic agent. Group: Pharmaceutical. CAS No. 85650-56-2. Pack Sizes: 1 g. Product ID: B0084-007055. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AT-406 | AT-406 is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3 (with Ki of 66.4 nM), cIAP1-BIR3(with Ki of 1.9 nM) and cIAP2-BIR3 (with Ki of 5.1 nM), respectively. Group: Pharmaceutical. CAS No. 1071992-99-8. Pack Sizes: 100 mg. Product ID: B0084-454116. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Atipamezole Impurities | Atipamezole Impurities, identified in the quality control of atipamezole formulations, are crucial in ensuring drug purity and safety. Atipamezole, an alpha-2 adrenergic antagonist, is used predominantly for reversing anesthesia in veterinary medicine. Monitoring these impurities is vital for mitigating adverse effects and optimizing therapeutic efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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