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| Product | Description | |
|---|---|---|
| Antagonist G | Antagonist G is a substance P analog, which is a broad spectrum neuropeptide growth factor antagonist and antiproliferative agent. It was developed for the treatment of small cell lung cancer. It could inhibit neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro. It also inhibits growth of SCLC xenografts in mice in vivo. It blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. It activates JNK and stimulates apoptosis. It is an anticancer agent and is resistant to degradation by peptidases. Group: Pharmaceutical. Alternative Names: [Arg6,D-Trp7,9,N-MePhe8]-Substance P(6-11). CAS No. 115150-59-9. Pack Sizes: 1 mg. Product ID: BAT-006104. Molecular formula: C49H66N12O6S. Mole weight: 951.2. Custom synthesis is available. Send your inquiries for more information. |  London |
| 5-HT3 antagonist 5 | 5-HT3 antagonist 5 is a 5-HT3 receptor antagonist with anti-depressant activity. Group: Pharmaceutical. Alternative Names: N-(4-methoxyphenyl)-2-quinoxalinecarboxamide. CAS No. 901599-43-7. Pack Sizes: 50 mg. Product ID: B1370-186731. Molecular formula: C16H13N3O2. Mole weight: 279.29. Custom synthesis is available. Send your inquiries for more information. | London |
| A2AR antagonist 1 | A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively. Group: Pharmaceutical. Alternative Names: 1-[(2-fluorophenyl)methyl]-4-(furan-2-yl)pyrazolo[3,4-d]pyrimidin-6-amine. CAS No. 443103-97-7. Pack Sizes: 1mg;1g;10g. Product ID: 443103-97-7. Molecular formula: C16H12FN5O. Mole weight: 309.3. Custom synthesis is available. Send your inquiries for more information. | London |
| A2B receptor antagonist 1 | A potent antagonist of A2B adenosine receptor. Group: Pharmaceutical. Alternative Names: 1H-Purine-2,6-dione, 3,9-dihydro-8-[1-(phenylmethyl)-1H-pyrazol-4-yl]-1,3-dipropyl-. CAS No. 531506-36-2. Pack Sizes: 1mg;1g;10g. Product ID: 531506-36-2. Molecular formula: C21H24N6O2. Mole weight: 392.45. Custom synthesis is available. Send your inquiries for more information. | London |
| A2B receptor antagonist 2 | A2B receptor antagonist 2 is a member of quinazolines. It is also an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively. Group: Pharmaceutical. Alternative Names: N-(4,6,7-trimethylquinazolin-2-yl)guanidine; 1-(4,6,7-trimethylquinazolin-2-yl)guanidine. CAS No. 784-90-7. Pack Sizes: 1mg;1g;10g. Product ID: 784-90-7. Molecular formula: C12H15N5. Mole weight: 229.28. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-(4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-5-yl)ethanone | An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. Alternative Names: 1-(4-(2-Hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-5-yl)ethanone; 1227626-50-7; 1-[5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]ethanone. CAS No. 1227626-50-7. Pack Sizes: 100 mg. Product ID: B0176-284898. Molecular formula: C44H42N6O2. Mole weight: 686.84. Custom synthesis is available. Send your inquiries for more information. | London |
| (1R,3S)-Solifenacin Hydrochloride | An impurity of Solifenacin. Solifenacin is a muscarinic M3 receptor antagonist for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence. Group: Pharmaceutical. Alternative Names: Solifenacin (R,S)-Isomer Hydrochloride Salt; (1R)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3S)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride. CAS No. 180468-40-0. Pack Sizes: 25 mg. Product ID: B1370-455505. Molecular formula: C23H27ClN2O2. Mole weight: 398.93. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate | 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]-ethanol-1-methanesulfonate is an intermediate of Silodosin, which is an α1-adrenergic receptor antagonist used for the treatment of benign prostatic hyperplasia. Group: Pharmaceutical. Alternative Names: 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]-ethanol 1-Methanesulfonate; 2-[2-Trifluoroethoxyphenoxy]ethyl methanesulfonate; Ethanol, 2-[2-(2,2,2-trifluoroethoxy)phenoxy]-, 1-methanesulfonate; methanesulfonic acid 2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl ester. CAS No. 160969-03-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3698. Molecular formula: C11H13F3O5S. Mole weight: 314.28. Custom synthesis is available. Send your inquiries for more information. | London |
| 2,2'-(2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-4,5-diyl)bis(propan-2-ol) | An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. CAS No. 1418133-29-5. Pack Sizes: 100 mg. Product ID: B0176-284894. Molecular formula: C45H46N6O2. Mole weight: 702.89. Custom synthesis is available. Send your inquiries for more information. | London |
| 2,2'-(((3aR,3a'R,4S,4'S,6R,6aS,6'R,6a'S)-6,6'-((5-nitro-2-(propylthio)pyrimidine-4,6-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))diethanol | An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. Alternative Names: 2,2'-(((3aR,3a'R,4S,4'S,6R,6aS,6'R,6a'S)-6,6'-((5-Nitro-2-(propylthio)pyrimidine-4,6-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))diethanol; B0027-284940. CAS No. 1882095-50-2. Pack Sizes: 100 mg. Product ID: B0027-284940. Molecular formula: C27H43N5O10S. Mole weight: 629.72. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol | 2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is an intermediate in the synthesis of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: (R)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol; (1R)-1-{3-[(E)-2-(7-Chloro-2-quinoleinyl)vinyl]phenyl}-3-[2-(2-hydroxy-2-propanyl)phenyl]-1-propanol; Benzenepropanol, α-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)-, (αR)-; (R,E)-1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol. CAS No. 150026-75-8. Pack Sizes: 100 mg. Product ID: B0052-208484. Molecular formula: C29H28ClNO2. Mole weight: 457.99. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol | 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is a montelukast impurity, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: A montelukast impurity. Group: Pharmaceutical. Alternative Names: Montelukast Diene; Montelukast Diol Impurity; Montelukast (3S)-Hydroxy Propanol; 2-[2-[3(S)-[3-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl-2-propanol. CAS No. 287930-77-2. Pack Sizes: 100 mg. Product ID: B1370-118426. Molecular formula: C29H28ClNO2. Mole weight: 457.99. Custom synthesis is available. Send your inquiries for more information. | London |
| [2-(Methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide | [2-(Methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide, an innovative pharmaceutical compound, plays a pivotal role in addressing a myriad of diseases by selectively modulating intricate cellular mechanisms. As an effective antagonist of key enzymes involved in the pathogenesis of malignant tumors, it is widely used in antimicrobial drug development. Group: Pharmaceutical. Alternative Names: 3-((2-(Methacryloyloxy)ethyl)dimethylammonio)propane-1-sulfonate; Dimethyl(2-((2-methyl-1-oxoallyl)oxy)ethyl)(3-sulphopropyl)ammonium hydroxide; N-(3-Sulfopropyl)-N-methacryloxyethyl-N,N-dimethylammonium betaine. CAS No. 3637-26-1. Pack Sizes: 1 kg. Product ID: B1370-091081. Molecular formula: C11H21NO5S. Mole weight: 279.35. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Propylsulfanyl-pyrimidin-4-ol | An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. Alternative Names: 4(1H)-Pyrimidinone, 2-(propylthio)-. CAS No. 54460-95-6. Pack Sizes: 100 mg. Product ID: B0027-284937. Molecular formula: C7H10N2OS. Mole weight: 170.23. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (2R,3R)-2,3-Dihydroxybutanedioate | An impurity of Bepotastine besylate, a histamine H1 receptor antagonist that has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus. Group: Pharmaceutical. Alternative Names: 2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine L-Tartrate. CAS No. 210095-58-2. Pack Sizes: 50 g. Product ID: B2694-014533. Molecular formula: C17H19ClN2O.C4H6O6. Mole weight: 452.89. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-(5-(2-aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate | 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate is an intermediate of Silodosin, which is an α1-adrenergic receptor antagonist used for the treatment of benign prostatic hyperplasia. Group: Pharmaceutical. Alternative Names: 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile-1H-indole (2R,3R)-2,3-dihydroxybutanedioate (1:1); (R)-5-(2-Aminopropyl)-1-(3-benzyloxypropyl)indoline-7-carbonitrile tartaric acid; (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate; 1H-Indole-7-carbonitrile, 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-, (2R,3R)-2,3-dihydroxybutanedioate (1:1). CAS No. 239463-85-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3475. Molecular formula: C22H25N3O2.C4H6O6. Mole weight: 513.54. Custom synthesis is available. Send your inquiries for more information. | London |
| 3,7-Dimethyl-1-propargylxanthine | 3,7-Dimethyl-1-propargylxanthine is a selective A2 adenosine receptor antagonist. It has been shown to be effective in vivo models of Parkinson's disease and has reduced locomotor activity. Group: Pharmaceutical. Alternative Names: DMPX; 3,7-Dimethyl-1-(prop-2-yn-1-yl)-1H-purine-2,6(3H,7H)-dione; 3,7-Dimethyl-1-(2-propynyl)xanthine. CAS No. 14114-46-6. Pack Sizes: 50 mg. Product ID: B1370-049568. Molecular formula: C10H10N4O2. Mole weight: 218.21. Custom synthesis is available. Send your inquiries for more information. | London |
| 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Group: Pharmaceutical. Alternative Names: 4,6-dichloro-2-(propylthio)pyrimidin-5-amine. CAS No. 145783-15-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3232. Molecular formula: C7H9Cl2N3S. Mole weight: 238.14. Custom synthesis is available. Send your inquiries for more information. | London |
| 4,6-Dichloro-5-nitro-2-propylthiopyrimidine | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Group: Pharmaceutical. Alternative Names: 4,6-dichloro-5-nitro-2-(propylthio)pyrimidine; 4,6-dichloro-5-nitro-2-propylsulfanylpyrimidine. CAS No. 145783-14-8. Pack Sizes: 1mg;1g;10g. Product ID: NP3231. Molecular formula: C7H7Cl2N3O2S. Mole weight: 268.12. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Chloro-2-propylsulfanyl-pyrimidine | An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. Alternative Names: Pyrimidine, 4-chloro-2-(propylthio)-. CAS No. 1351990-36-7. Pack Sizes: 100 mg. Product ID: B0027-284938. Molecular formula: C7H9ClN2S. Mole weight: 188.673. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-(Hydroxymethyl)benzoic acid | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Uses: 4-(hydroxymethyl)benzoic acid (eprosartan usp related compound e) is an intermediate in the synthesis of eprosartan (e590100), a prototype of the imidazoleacrylic acid angiotensin ii receptor antagonists used as an antihypertensive agent. Group: Pharmaceutical. Alternative Names: HMBA Linker; 4-Carboxybenzyl Alcohol; p-(Hydroxymethyl)benzoic Acid; p-Carboxybenzyl Alcohol; α-Hydroxy-p-toluic Acid; α-Hydroxy-p-toluic Acid; 4-(hydroxymethyl)benzoic Acid; USP Eprosartan Related Compound E; USP Ecamsule Related Compound B; Eprosartan USP Related Compound E; para-hydroxymethylbenzoic acid. CAS No. 3006-96-0. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008049. Molecular formula: C8H8O3. Mole weight: 152.15. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(2-Chlorobenzyl)thieno(3,2-C)pyridinium chloride | 5-(2-Chlorobenzyl)thieno(3,2-C)pyridinium chloride is an impurity of Ticlopidine, a reversible P2Y12 receptor antagonist used to decrease the risk of stroke in patients known to have atherosclerosis. Group: Pharmaceutical. Alternative Names: 5-(2-Chlorobenzyl)-thieno[3,2-c]pyridinium Chloride; 5-[(2-Chlorophenyl)methyl]-thieno[3,2-c]pyridinium Chloride. CAS No. 53885-64-6. Pack Sizes: 25 mg. Product ID: B1370-469260. Molecular formula: C14H11Cl2NS. Mole weight: 296.21. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4'-(azidomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Group: Pharmaceutical. Alternative Names: 5-(4'-(Azidomethyl)(1,1'-biphenyl)-2-yl)-1H-tetrazole; Valsartan azide impurity. CAS No. 152708-24-2. Pack Sizes: 25 mg. Product ID: B2694-376321. Molecular formula: C14H11N7. Mole weight: 277.28. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate | An impurity of Prasugrel. Prasugrel is a platelet inhibitor and an irreversible antagonist of P2Y12ADP receptors that prevents the formation of blood clots. It was appoved for the treatment of acute coronary syndrome (ACS), and some cardiovascular diseasess in combination with Aspirin. Group: Pharmaceutical. Alternative Names: 5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate maleate; Prasugrel Impurity 4. CAS No. 1373350-61-8. Pack Sizes: 20 mg. Product ID: B0219-007244. Molecular formula: C24H25ClFNO7S. Mole weight: 525.972. Custom synthesis is available. Send your inquiries for more information. | London |
| (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-methoxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate | An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. CAS No. 1040405-56-8. Pack Sizes: 100 mg. Product ID: B0176-284897. Molecular formula: C49H46N6O6. Mole weight: 814.93. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Aminoisoindolin-1-one | 6-Aminoisoindolin-1-one is used in the synthesis of a novel potent glycoprotein IIb-IIIa (GP IIb-IIIa) receptor antagonist based on the isoindolone skeleton. Group: Pharmaceutical. Alternative Names: 6-amino-2,3-dihydro-1H-isoindol-1-one. CAS No. 675109-45-2. Pack Sizes: 10 g. Product ID: BB033299. Molecular formula: C8H8N2O. Mole weight: 148.16. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride | An impurity of Paliperidone which functions as a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Group: Pharmaceutical. Alternative Names: Paliperidone USP RC B; Paliperidone Amine Impurity ; Risperidone EP Impurity M ; 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride. CAS No. 84163-13-3. Pack Sizes: 1mg;1g;10g. Product ID: NP3487. Molecular formula: C12H13FN2O.HCl. Mole weight: 256.71. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Keto Fulvestrant | 6-Keto Fulvestrant is an impurity of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Group: Pharmaceutical. Alternative Names: 6-Keto-Fulvestrant; (7a,17ss)-7-[9-[4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]-3,17ss-dihydroxyestra-1,3,5(10)-trien-6-one. Pack Sizes: 10 mg. Product ID: B2694-471908. Molecular formula: C32H45F5O4S. Mole weight: 620.77. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Hydroxy Methotrexate | 7-Hydroxy Methotrexate is a metabolite of Methotrexate, which is used as an antineoplastic and antirheumatic. Uses: Folic acid antagonists. Group: Pharmaceutical. Alternative Names: Methotrexate 7-Hydroxy Metabolite; 7-Hydroxy Amethopterin; (4-(((2,4-Diamino-7-hydroxypteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic Acid. CAS No. 5939-37-7. Pack Sizes: 10 mg. Product ID: B1370-128412. Molecular formula: C20H22N8O6. Mole weight: 470.44. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Methoxy-1-tetralone | 7-Methoxy-1-tetralone is an impurity of Agomelatine, which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors. Group: Pharmaceutical. Alternative Names: 1(2H)-Naphthalenone, 3,4-dihydro-7-methoxy-; 3,4-Dihydro-7-methoxy-1(2H)-naphthalenone; 7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenone; 7-Methoxy-1,2,3,4-tetrahydro-1-oxonaphthalene; 7-Methoxy-3,4-dihydro-1(2H)-naphthalenone; 7-Methoxy-α-tetralone; 7-Methoxytetralin-1-one; 7-Methoxytetralone; NSC 97611. CAS No. 6836-19-7. Pack Sizes: 1mg;1g;10g. Product ID: NP3695. Molecular formula: C11H12O2. Mole weight: 176.21. Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Deschloro-8-bromo-N-methyl Desloratadine | 8-Deschloro-8-bromo-N-methyl Desloratadine is one of Loratadine derivatives. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Group: Pharmaceutical. Alternative Names: 8-Bromo-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 8-Bromo-11-(1-methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-bromo-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-; Desloratadine Impurity 18. CAS No. 130642-57-8. Pack Sizes: 25 mg. Product ID: B1370-118732. Molecular formula: C20H21BrN2. Mole weight: 369.3. Custom synthesis is available. Send your inquiries for more information. | London |
| A 1120 | A 1120 is a retinol-binding protein 4 (RBP4) antagonist (Ki = 8.3 nM) that can reduce serum RBP4 and retinol, and displaces transthyretin (TTR) from RBP4-TTR complexes. Group: Pharmaceutical. Alternative Names: A-1120; A1120; 2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid. CAS No. 1152782-19-8. Pack Sizes: 100 mg. Product ID: B1370-271974. Molecular formula: C20H19F3N2O3. Mole weight: 392.37. Custom synthesis is available. Send your inquiries for more information. | London |
| A-1165442 | A-1165442 is a potent, competitive and orally available modality-differentiated second-generation TRPV1 antagonist with good analgesic efficacy and a temperature-neutral profile (IC50 = 9 nM for human TRPV1). Group: Pharmaceutical. Alternative Names: A1165442; A 1165442; A-1165442; 1-[(4R)-7-chloro-2,2-bis(fluoromethyl)-3,4-dihydrochromen-4-yl]-3-(3-methylisoquinolin-5-yl)urea; 1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea. CAS No. 1221443-94-2. Pack Sizes: 1mg;1g;10g. Product ID: 1221443-94-2. Molecular formula: C22H20ClF2N3O2. Mole weight: 431.86. Custom synthesis is available. Send your inquiries for more information. | London |
| A 127722 | A 127722 is a potent and selective ETA endothelin receptor antagonist (IC50 = 0.11 nM and 98 nM for human ETA and ETB receptors, respectively). It attenuates hypoxia-induced pulmonary hypertension in rats. Group: Pharmaceutical. Alternative Names: A-127722; A127722; rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid. CAS No. 195704-72-4. Pack Sizes: 1mg;1g;10g. Product ID: 195704-72-4. Molecular formula: C29H38N2O6. Mole weight: 510.62. Custom synthesis is available. Send your inquiries for more information. | London |
| A-192621 | A-192621 is a selective antagonist at endothelin ETB receptor with more effective than IRL-2500 in blocking IRL-1620-induced vasoconstriction, but both augmented constrictor responses to ET-1. Group: Pharmaceutical. Alternative Names: (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(2,6-diethylanilino)-2-oxoethyl]-2-(4-propoxyphenyl)pyrrolidine-3-carboxylic acid; (2R-(2alpha,3beta,4alpha)-4-(1,3-benzodioxol-5-yl)-1-(2-(2,6-diethylphenyl)amino)-2-oxoethyl)-2-(4-propoxyphenyl)-3-pyrrolidinecarboxylic acid; A 192621; A-192621; A192621. CAS No. 195529-54-5. Pack Sizes: 1mg;1g;10g. Product ID: 195529-54-5. Molecular formula: C33H38N2O6. Mole weight: 558.675. Custom synthesis is available. Send your inquiries for more information. | London |
| A1B1 hydrochloride | A1B1 hydrochloride is a potent and orally-available chemokine CCR1 antagonist. Group: Pharmaceutical. Alternative Names: N-[5-chloro-2-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide hydrochloride. Pack Sizes: 1mg;1g;10g. Molecular formula: C23H25ClFN3O2.HCl. Mole weight: 466.38. Custom synthesis is available. Send your inquiries for more information. | London |
| A-317491 | A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Group: Pharmaceutical. Alternative Names: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. CAS No. 475205-49-3. Pack Sizes: 1mg;1g;10g. Product ID: 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A-317491 sodium salt hydrate | A-317491 sodium salt hydrate is a potent, selective antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. It reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Molecular formula: C33H29NNaO9. Mole weight: 606.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A 331440 dihydrochloride | A 331440 dihydrochloride is a histamine H3 receptor antagonist (Ki = 21.7 and 22.7 nM for rat and human H3 receptors, respectively). A 331440 reduces weight in a diet-induced obesity model. Group: Pharmaceutical. Alternative Names: A-331440 dihydrochloride; A 331440 dihydrochloride; A331440 dihydrochloride; 4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride. CAS No. 1049740-32-0. Pack Sizes: 1mg;1g;10g. Product ID: 1049740-32-0. Molecular formula: C22H27N3O.2HCl. Mole weight: 422.39. Custom synthesis is available. Send your inquiries for more information. | London |
| A-395 | A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions, and can effectively inhibit the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM. Group: Pharmaceutical. Alternative Names: 3-Pyrrolidinamine, 1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-[4-[4-(methylsulfonyl)-1-piperazinyl]phenyl]-, (3R,4S)-; (3R,4S)-1-(7-Fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-{4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-3-pyrrolidinamine. CAS No. 2089148-72-9. Pack Sizes: 1mg;1g;10g. Product ID: 2089148-72-9. Molecular formula: C26H35FN4O2S. Mole weight: 486.65. Custom synthesis is available. Send your inquiries for more information. | London |
| A 410099.1 | A 410099.1 is a high affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells. Group: Pharmaceutical. Alternative Names: N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride. CAS No. 762274-58-8. Pack Sizes: 1mg;1g;10g. Product ID: 762274-58-8. Molecular formula: C27H40N4O3·HCl. Mole weight: 505.09. Custom synthesis is available. Send your inquiries for more information. | London |
| A 425619 | A 425619 is a potent and selective TRPV1 antagonist (IC50 = 3-9 nM) that inhibits TRPV1 activation by anandamide and N-arachidonoyl-dopamine. A 425619 exhibits an inhibitory effect against inflammatory, postoperative and osteoarthritic in vivo pain models. Uses: Analgesic. Group: Pharmaceutical. Alternative Names: A-425619; A 425619; A425619; N-5-Isoquinolinyl-N'-[[(4-(trifluoromethyl)phenyl]methyl]urea. CAS No. 581809-67-8. Pack Sizes: 1mg;1g;10g. Product ID: 581809-67-8. Molecular formula: C18H14F3N3O. Mole weight: 345.32. Custom synthesis is available. Send your inquiries for more information. | London |
| A 437203 | A 437203 is a selective dopamine (DA) D3 receptor antagonist suited to evaluate the physiological role(s) of D3 receptors. A 437203 shows an approximately 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors. Group: Pharmaceutical. Alternative Names: 2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one; 2-(3-(4-(2-tert-butyl-6-trifluoromethylpyrimidin-4-yl)piperazin-1-yl)propylsulfanyl)-3H-pyrimidin-4-one fumarate; A 437203; A-437203; A437203; 1160247-85-7; 220519-07-3 (anhydrous); 220519-06-2 (anhydrous free base). CAS No. 220519-06-2. Pack Sizes: 1mg;1g;10g. Product ID: 220519-06-2. Molecular formula: C20H27F3N6OS. Mole weight: 456.53. Custom synthesis is available. Send your inquiries for more information. | London |
| A-438079 HCl | A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9. Group: Pharmaceutical. Alternative Names: A-438079 HCl; A 438079 HCl; A438079 HCl. CAS No. 899431-18-6. Pack Sizes: 1mg;1g;10g. Product ID: 899431-18-6. Molecular formula: C13H10Cl3N5. Mole weight: 342.61. Custom synthesis is available. Send your inquiries for more information. | London |
| A 438079 hydrochloride | A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores. Group: Pharmaceutical. Alternative Names: 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride; A438079 hydrochloride; A 438079 hydrochloride. CAS No. 899507-36-9. Pack Sizes: 1mg;1g;10g. Product ID: 899507-36-9. Molecular formula: C13H10Cl3N5. Mole weight: 342.61. Custom synthesis is available. Send your inquiries for more information. | London |
| A-740003 | A-740003 is potent, selective and competitive P2X7 receptor antagonist. Its IC50 values are 18 and 40 nM for rat and human receptors respectively measured by agonist-stimulated changes in intracellular calcium concentrations. It displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. It reduces nociception in animal models of persistent neuropathic and inflammatory pain. It showed weak or no activity (IC(50) > 10 muM) at other P2 receptors and an array of other neurotransmitter and peptide receptors, ion channels, reuptake sites, and enzymes. It potently blocked agonist-evoked IL-1beta release (IC(50) = 156 nM) and pore formation (IC(50) = 92 nM) in differentiated human THP-1 cells. It produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Uses: A-740003 produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Group: Pharmaceutical. Alternative Names: A-740003; A 740003; A740003; N-[1-[[(Cyanoamino)(5-quinolinylimino)methyl]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide;N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide. CAS No. 861393-28-4. Pack Sizes: 1mg;1g;10g. Product ID: 861393-28-4. Molecular formula: C26H30N6O3. Mole weight: 474.55. Custom synthesis is available. Send your inquiries for more information. | London |
| A 779 | A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor) (IC50 = 0.3 nM) with no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. Group: Pharmaceutical. Alternative Names: A-779; A779; (D-Ala7)-Angiotensin I/II (1-7); Asp-Arg-Val-Tyr-Ile-His-D-Ala-OH; 5-L-isoleucine-7-D-alanine-1-7-angiotensin II; 7-Ala-angiotensin (1-7); A 778; A 779; A-778; A779 peptide; angiotensin (1-7), Ala(7)-; angiotensin (1-7), alanyl(7)-; Asp-Arg-Val-Tyr-Ile-His-Ala; aspartyl-arginyl-valyl-tyrosyl-isoleucyl-histidyl-alanine. CAS No. 159432-28-7. Pack Sizes: 10 mg. Product ID: BAT-006218. Molecular formula: C39H60N12O11. Mole weight: 872.97. Custom synthesis is available. Send your inquiries for more information. | London |
| A 784168 | A 784168 is a potent and selective TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin) exhibiting no activity against a range of receptors such as TRPA1, GABA, opioid, and purinergic receptors. Group: Pharmaceutical. Alternative Names: A 784168; A784168; A-784168; 3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide; 1-[3-(trifluoromethyl)pyridin-2-yl]-N-[4-(trifluoromethylsulfonyl)phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide. CAS No. 824982-41-4. Pack Sizes: 1mg;1g;10g. Product ID: 824982-41-4. Molecular formula: C19H15F6N3O3S. Mole weight: 479.4. Custom synthesis is available. Send your inquiries for more information. | London |
| A-7 hydrochloride | A-7 hydrochloride is a cell-permeable antagonist of calmodulin that inhibits calmodulin-activated PDE activity with an IC50 of 3 μM. Calmodulin is a calcium-dependent protein expressed in all eukaryotic cells, modulating the interaction of calcium with target proteins. Group: Pharmaceutical. Alternative Names: A-7 monohydrochloride; A 7 hydrochloride; A7 hydrochloride; N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide hydrochloride; N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide monoydrochloride. CAS No. 79127-24-5. Pack Sizes: 1mg;1g;10g. Product ID: 79127-24-5. Molecular formula: C20H29ClN2O2S.HCl. Mole weight: 433.44. Custom synthesis is available. Send your inquiries for more information. | London |
| A 80426 | A 80426 is a potent α2-adrenoceptor antagonist and a selective 5-HT uptake inhibitor (Ki = 2.01 and 3.77 nM, respectively). It displays low affinity for a panel of structurally homologous GPCRs. Group: Pharmaceutical. Alternative Names: A-80426; A80426; (R)-2-(Benzofuran-6-yl)-N-((5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)-N-methylethanamine. CAS No. 152148-63-5. Pack Sizes: 1mg;1g;10g. Product ID: 152148-63-5. Molecular formula: C23H27NO2. Mole weight: 349.5. Custom synthesis is available. Send your inquiries for more information. | London |
| A 80426 mesylate | A 80426 mesylate is a potent α2-adrenoceptor antagonist and a selective 5-HT uptake inhibitor (Ki = 2.01 and 3.77 nM, respectively). It displays low affinity for a panel of structurally homologous GPCRs. Group: Pharmaceutical. Alternative Names: A-80426 mesylate; A 80426 mesylate; A80426 mesylate; N-Methyl-N-[[(1R)-1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl]methyl]-6-benzofuranethanamine mesylate. CAS No. 152148-64-6. Pack Sizes: 1mg;1g;10g. Product ID: 152148-64-6. Molecular formula: C23H27NO2.CH3SO3H. Mole weight: 445.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A 804598 | A 804598 is a potent and competitive P2X7 receptor antagonist (IC50 = 8.9, 9.9 and 10.9 nM for mouse, rat and human P2X7 receptors, respectively). Group: Pharmaceutical. Alternative Names: A-804598; A 804598; A804598. N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine; 1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine. CAS No. 1125758-85-1. Pack Sizes: 1mg;1g;10g. Product ID: 1125758-85-1. Molecular formula: C19H17N5. Mole weight: 315.37. Custom synthesis is available. Send your inquiries for more information. | London |
| A81988 | A81988 is a potent, orally active angiotensin I1 antagonist with a long duration of action whose pharmacological profile has established it as an important tool for the investigation of a variety of A11 mediated pathological conditions. Uses: Angiotensin ii type 1 receptor blockers. Group: Pharmaceutical. Alternative Names: 2-[propyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyridine-3-carboxylic acid; 2-(N-propyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)amino)pyridine-3-carboxylic acid; A 81988; A-81988; A81988; Abbott 81988; Abbott-81988. CAS No. 141887-34-5. Pack Sizes: 1mg;1g;10g. Product ID: 141887-34-5. Molecular formula: C23H22N6O2. Mole weight: 414.46. Custom synthesis is available. Send your inquiries for more information. | London |
| A 839977 | A-839977 is a novel and selective P2X7 antagonist. It blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors with IC50 values 20, 42 and 150 nM respectively. It also potently blocked agonist-evoked YO-PRO uptake and IL-1beta release from differentiated human THP-1 cells. It also produced robust antihyperalgesia in the CFA model of inflammatory pain in wild-type mice. It has been exhibited to reduce CFA-induced thermal hyperalgesia in a dose-dependent fashion with the ED50 value of 100μmol/kg. Group: Pharmaceutical. Alternative Names: 1-(2,3-Dichlorophenyl)-N-[[2-[(pyridin-2-yl)oxy]phenyl]methyl]-1H-tetrazol-5-amine. CAS No. 870061-27-1. Pack Sizes: 1mg;1g;10g. Product ID: 870061-27-1. Molecular formula: C19H14Cl2N6O. Mole weight: 413.26. Custom synthesis is available. Send your inquiries for more information. | London |
| A 841720 | A 841720 is a potent non-competitive mGlu1 receptor antagonist (IC50 = 10 nM) exhibiting 34-fold selectivity over mGluR5 and inactive to other mGluR receptors, neurotransmitter receptors, ion channels, and transporters. It inhibits complete Freund's adjuvant-induced inflammatory pain (ED50 = 23 μmol/kg) and decreases mechanical allodynia (ED50 = 28 μmol/kg) in mouse models. Group: Pharmaceutical. Alternative Names: A-841720; A 841720; A841720; 3-(azepan-1-yl)-9-(dimethylamino)pyrido[1,2]thieno[3,4-d]pyrimidin-4-one. CAS No. 869802-58-4. Pack Sizes: 1mg;1g;10g. Product ID: 869802-58-4. Molecular formula: C17H21N5OS. Mole weight: 343.45. Custom synthesis is available. Send your inquiries for more information. | London |
| A 943931 | A 943931 is a potent and selective histamine H4 receptor antagonist. Group: Pharmaceutical. Alternative Names: A-943931; A 943931; A943931; D0P8DW; 4-[(3R)-3-aminopyrrolidin-1-yl]-6,7-dihydro-5H-benzo[1,2]cyclohepta[3,4-b]pyrimidin-2-amine. CAS No. 1027330-97-7. Pack Sizes: 1mg;1g;10g. Product ID: 1027330-97-7. Molecular formula: C17H21N5. Mole weight: 295.38. Custom synthesis is available. Send your inquiries for more information. | London |
| A 943931 dihydrochloride | A 943931 dihydrochloride is a potent and selective histamine H4 receptor antagonist (pKi = 7.15 and 8.12 at human and rat receptors, respectively). A 943931 blocks inflammation in a peritonitis mouse model and displays efficacy in inflammatory pain and neuropathic pain models. Group: Pharmaceutical. Alternative Names: A 943931 dihydrochloride; A943931 dihydrochloride; A-943931 dihydrochloride; 4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine. CAS No. 1227675-50-4. Pack Sizes: 1mg;1g;10g. Product ID: 1227675-50-4. Molecular formula: C17H21N5.2HCl. Mole weight: 368.31. Custom synthesis is available. Send your inquiries for more information. | London |
| A 987306 | A 987306 is a potent histamine H4 receptor antagonist (pKi = 8.24 and 8.47 in human and rat H4 receptors, respectively) with 162-, 620-, and > 1600-fold selectivity over human H3, H1 and H2 receptors. It suppresses zymosan-induced neutrophil reflux and attenuates thermal hypersensitivity in vivo (ED50 = 42 μmol/kg, ip). Group: Pharmaceutical. Alternative Names: A 987306; A987306; A-987306; (±)-(7aR,11aR)-5,6,7a,8,9,10,11,11a-Octahydro-4-(1-piperazinyl)-benzofuran[2,3-h]quinazolin-2-amine. CAS No. 1082954-71-9. Pack Sizes: 1mg;1g;10g. Product ID: 1082954-71-9. Molecular formula: C18H25N5O. Mole weight: 327.42. Custom synthesis is available. Send your inquiries for more information. | London |
| AA41612 | AA41612 is a novel antagonist of melanopsin-mediated phototransduction. Group: Pharmaceutical. Alternative Names: AA 41612; AA-41612; 1-((2,5-Dichloro-4-methoxyphenyl)sulfonyl)piperidine. CAS No. 433690-62-1. Pack Sizes: 1mg;1g;10g. Product ID: 433690-62-1. Molecular formula: C12H15Cl2NO3S. Mole weight: 324.22. Custom synthesis is available. Send your inquiries for more information. | London |
| AA92593 | AA92593 is a selective and competitive OPN4 (melanopsin) antagonist. It blocks melanopsin activity and stimulates α-melanocyte-stimulating hormone (α-MSH) expression and induces melanin distribution in the melanophores, which darkens the embryo. Group: Pharmaceutical. Alternative Names: 1-((4-Methoxy-3-methylphenyl)sulfonyl)piperidine. CAS No. 457961-34-1. Pack Sizes: 1mg;1g;10g. Product ID: 457961-34-1. Molecular formula: C13H19NO3S. Mole weight: 269.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Aaptamine | Aaptamine, a spongean alkaloid isolated from a sea sponge Aaptos aaptos, is a competitive antagonist of α-adrenoceptor and activates the p21 promoter in a p53-independent manner. Group: Pharmaceutical. Alternative Names: 8,9-dimethoxy-1H-benzo[de][1,6]naphthyridine. CAS No. 85547-22-4. Pack Sizes: 1mg;1g;10g. Product ID: 85547-22-4. Molecular formula: C13H12N2O2. Mole weight: 228.3. Custom synthesis is available. Send your inquiries for more information. | London |
| AAT-008 | AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4; IC50 = 16.3 nM in a human EP4 functional assay). Group: Pharmaceutical. Alternative Names: 4-[(1S)-1-[[5-chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acid. CAS No. 847727-81-5. Pack Sizes: 1mg;1g;10g. Product ID: 847727-81-5. Molecular formula: C21H16ClFN2O4. Mole weight: 414.8. Custom synthesis is available. Send your inquiries for more information. | London |
| AB928 | AB928 is a dual antagonist of the A2aR and A2bR adenosine receptors with Kb of 1.5 and 2.0 nM, respectively. It potently blocks the immunosuppressive effects of high adenosine concentrations in the tumor microenvironment. Group: Pharmaceutical. Alternative Names: A2Ar/A2bR antagonist-1; 3-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile. CAS No. 2239273-34-6. Pack Sizes: 50 mg. Product ID: B2693-334167. Molecular formula: C23H22N8O. Mole weight: 426.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Abanoquil mesilate | This molecular is an active biochemical as a Alpha 1 adrenergic receptor antagonist. However, no developments were reported for Ischaemic heart disorders and Arrhythmias. Uses: Arrhythmias; ischaemic heart disorders. Group: Pharmaceutical. Alternative Names: 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine;methanesulfonic acid,TCMDC-131968, TCMDC 131968, TCMDC131968, UK 52046; UK-52046; UK52046; Abanoquil. CAS No. 118931-00-3. Pack Sizes: 1mg;1g;10g. Product ID: 118931-00-3. Molecular formula: C23H29N3O7S. Mole weight: 491.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Abaperidone | Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with IC50s of 6.2 and 17 nM, respectively. Group: Pharmaceutical. Alternative Names: 7-(3-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3-(hydroxymethyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 7-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(hydroxymethyl)-. CAS No. 183849-43-6. Pack Sizes: 1mg;1g;10g. Product ID: 183849-43-6. Molecular formula: C25H25FN2O5. Mole weight: 452.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Group: Pharmaceutical. Alternative Names: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. CAS No. 183552-38-7. Pack Sizes: 10 mg. Product ID: BAT-006166. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. Custom synthesis is available. Send your inquiries for more information. | London |
| ABD459 | ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). Group: Pharmaceutical. Alternative Names: [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl](4-methoxyphenyl)-methanone. CAS No. 1047670-51-8. Pack Sizes: 1mg;1g;10g. Product ID: 1047670-51-8. Molecular formula: C24H17BrCl2N2O2. Mole weight: 516.2. Custom synthesis is available. Send your inquiries for more information. | London |
| Ablukast | Ablukast, a specific and active leukotriene receptor antagonist, effectively reduces LTC4- and antigen-induced bronchoconstriction. It is an LTD4 receptor antagonist with anti-asthmatic effect. Group: Pharmaceutical. Alternative Names: Ro 23-3544; 6-Acetyl-7-(5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyloxy)-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid; 2H-1-Benzopyran-2-carboxylic acid, 6-acetyl-7-((5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl)oxy)-3,4-dihydro-, (±)-. CAS No. 96566-25-5. Pack Sizes: 1mg;1g;10g. Product ID: 96566-25-5. Molecular formula: C28H34O8. Mole weight: 498.56. Custom synthesis is available. Send your inquiries for more information. | London |
| ABP 688 | ABP 688 is a high affinity human mGlu5 receptor antagonist (Ki = 1.7 nM) that inhibits the release of glutamate-induced calcium from L(tk-) cells expressing human mGlu5 receptors (IC50 = 2.3 nM). Group: Pharmaceutical. Alternative Names: ABP688; ABP-688; ABP 688; 3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime; N-methoxy-3-[2-(6-methylpyridin-2-yl)ethynyl]cyclohex-2-en-1-imine. CAS No. 924298-51-1. Pack Sizes: 1mg;1g;10g. Product ID: 924298-51-1. Molecular formula: C15H16N2O. Mole weight: 240.3. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT-102 | ABT 102 is a selective transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with IC50 values to be 5-7 nM. No recent reports of development identified for phase-I development in Pain in USA. Uses: Pain. Group: Pharmaceutical. Alternative Names: ABT 102; ABT-102; ABT102; CHEMBL398338; 1-[(1R)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-3-(1H-indazol-4-yl)urea. CAS No. 808756-71-0. Pack Sizes: 1mg;1g;10g. Product ID: 808756-71-0. Molecular formula: C21H24N4O. Mole weight: 348.44. Custom synthesis is available. Send your inquiries for more information. | London |
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