Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| 8-Anilino-1-naphthalenesulfonic acid (Phenyl peri acid) | 25g Pack Size. Group: Amines, Building Blocks, Organics, Stains & Indicators. Formula: C6H5NHC10H6SO3H. CAS No. 82-76-8. Prepack ID : 12709547-25g. Molecular Weight : 299.34. |  |
| Amenamevir | Amenamevir is a DNA helicase-primase inhibitor. It has anti-HSV activity against herpes simplex keratitis. In Mar 2016, Mahuro completed a phase III trial in Herpes simplex virus infections in Japan. Uses: Herpes simplex virus infections; herpes zoster. Group: Pharmaceutical. Alternative Names: UNII-94X46KW4AE; ASP2151; N-(2,6-dimethylphenyl)-N-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxoethyl]-1,1-dioxothiane-4-carboxamide. CAS No. 841301-32-4. Pack Sizes: 10 mg. Product ID: B0084-459784. Molecular formula: C24H26N4O5S. Mole weight: 482.55. Custom synthesis is available. Send your inquiries for more information. |  London |
| Atorvastatin calcium trihydrate | Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Uses: An inhibitor of hmg-coa reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Group: Pharmaceutical. Alternative Names: CI-981; CI 981; CI981; calcium bis{(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate} trihydrate. CAS No. 344423-98-9. Pack Sizes: 10 g. Product ID: B1370-241758. Molecular formula: C66H74CaF2N4O13. Mole weight: 1209.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Bumadizone | Bumadizone is a non-steroidal anti-inflammatory drug (NSAID). Group: Pharmaceutical. Alternative Names: 2-[anilino(phenyl)carbamoyl]hexanoic acid. CAS No. 3583-64-0. Pack Sizes: 1mg;1g;10g. Product ID: 3583-64-0. Molecular formula: C19H22N2O3. Mole weight: 326.396. Custom synthesis is available. Send your inquiries for more information. | London |
| Cerdulatinib HCl | Cerdulatinib is a dual SYK/JAK inhibitor. It significantly reduces cell viability in a subset of NHL cell lines, and induces apoptosis in BCR-signaling competent NHL cell lines. Group: Pharmaceutical. Alternative Names: Cerdulatinib hydrochloride; PRT2070 hydrochloride; 4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide hydrochloride. CAS No. 1369761-01-2. Pack Sizes: 10 mg. Product ID: B0084-463402. Molecular formula: C20H28ClN7O3S. Mole weight: 482. Custom synthesis is available. Send your inquiries for more information. | London |
| GW4869 | GW4869 is a cell-permeable, specific and non-competitive inhibitor of neutral sphingomyelinases (IC50 = 1 μM). Group: Pharmaceutical. Alternative Names: (E)-3-[4-[(E)-3-[4-(4,5-dihydro-1H-imidazol-2-yl)anilino]-3-oxoprop-1-enyl]phenyl]-N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]prop-2-enamide;dihydrochloride; GW 4869; GW-4869. CAS No. 6823-69-4. Pack Sizes: 10 mg. Product ID: B0084-301751. Molecular formula: C30H30Cl2N6O2. Mole weight: 577.5. Custom synthesis is available. Send your inquiries for more information. | London |
| HG-9-91-01 | HG-9-91-01,a small molecule inhibitor that targets specificly salt-inducible kinase (SIKs) IC50: SIK1=0.92 nM; SIK2=6.6 nM; SIK3=9.6 nM. Group: Pharmaceutical. Alternative Names: 1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]ureaHG-9-91-01; HG-9-91-01; HG 9-91-01; HG9-91-01; HG99101; HG-99101; HG 99101;GTPL8049SCHEMBL15271960BDBM192712CS-1749HG-9-91-01 (1)1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiper. CAS No. 1456858-58-4. Pack Sizes: 5 mg. Product ID: B0084-474589. Molecular formula: C32H37N7O3. Mole weight: 567.68. Custom synthesis is available. Send your inquiries for more information. | London |
| Mc-Val-Cit-PAB-Cl | Mc-Val-Cit-PAB-Cl. Group: Pharmaceutical. Alternative Names: N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(chloromethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-6-(2,5-dioxopyrrol-1-yl)hexanamide. CAS No. 1639351-92-0. Pack Sizes: 10 mg. Product ID: BADC-00610. Molecular formula: C28H39ClN6O6. Mole weight: 591.1. Custom synthesis is available. Send your inquiries for more information. | London |
| MK-1775 | MK-1775, also known as AZD-1775, is a WEE1 inhibitor and a small-molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. Unlike normal cells, most p53-deficient or mutated human cancers lack the G1 checkpoint as p53 is the key regulator of the G1 checkpoint and these cells rely on the G2 checkpoint for DNA repair to damaged cells. Annulment of the G2 checkpoint may therefore make p53-deficient tumor cells more vulnerable to antineoplastic agents and enhance their cytotoxic effect. Group: Pharmaceutical. Alternative Names: MK-1775; MK1775; MK 1775; AZD1775; AZD-1775; AZD 1775; adavosertib. 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one. CAS No. 955365-80-7. Pack Sizes: 300 mg. Product ID: B0084-157422. Molecular formula: C27H32N8O2. Mole weight: 500.607. Custom synthesis is available. Send your inquiries for more information. | London |
| MRT67307 | This active molecular is a potent ULK1/2 inhibitor and the IC50 value is 2.9 nM and 1.1 nM. MRT68921 is also a SIK inhibitor. Group: Pharmaceutical. Alternative Names: MRT67307; MRT 67307; MRT-67307; N-[3-[[5-cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide,1190379-70-4 (HCl). CAS No. 1190378-57-4. Pack Sizes: 10 mg. Product ID: B2693-457418. Molecular formula: C26H36N6O2. Mole weight: 464.61. Custom synthesis is available. Send your inquiries for more information. | London |
| Neratinib | Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Group: Pharmaceutical. Alternative Names: 2-Butenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide; (E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide; (E)-N-[4-[[3-Chloro-4-((pyridin-2-yl)meth. CAS No. 698387-09-6. Pack Sizes: 500 mg. Product ID: B0084-347125. Molecular formula: C30H29ClN6O3. Mole weight: 557.04. Custom synthesis is available. Send your inquiries for more information. | London |
| P7C3 | P7C3 is a proneurogenic and neuroprotective agent that activates NAMPT. P7C3 protects neurons from apoptosis and promotes neurogenesis in mice. It also improves cognitive function and memory in aged mice. Group: Pharmaceutical. Alternative Names: 1-Anilino-3-(3,6-dibromocarbazol-9-yl)propan-2-ol; 1-(3,6-Dibromo-carbazol-9-yl)-3-phenylamino-propan-2-ol; 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol; 1-(3,6-dibromocarbazol-9-yl)-3-(phenylamino)propan-2-ol. CAS No. 301353-96-8. Pack Sizes: 50 mg. Product ID: B0084-350804. Molecular formula: C21H18Br2N2O. Mole weight: 474.196. Custom synthesis is available. Send your inquiries for more information. | London |
| Purvalanol A | Purvalanol A is a potent CDK inhibitor, which effectively suppresses Src-mediated transformation by inhibiting both CDKs and c-Src. indicating that the activation of CDKs contributes to the c-Src transformation. Purvalanol A suppressed the c-Src activity as effectively as the Src-selective inhibitor PP2, and that it reverted the transformed morphology to a nearly normal shape with less cytotoxicity than PP2. Purvalanol A induced a strong G2-M arrest, whereas PP2 weakly acted on the G1-S transition. Furthermore, when compared with PP2, purvalanol A more effectively suppressed the growth of human colon cancer HT29 and SW480 cells, in which Src family kinases and CDKs are activated. These findings demonstrate that the coordinated inhibition of cell cycle progression and tyrosine kinase signaling by the multi-selective purvalanol A is effective in suppressing cancer progression associated with c-Src up-regulation. Group: Pharmaceutical. Alternative Names: Purv; NG60; NG-60; NG 60; 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine; 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine. CAS No. 212844-53-6. Pack Sizes: 100 mg. Product ID: B1370-102089. Molecular formula: C19H25ClN6O. Mole weight: 388.89. Custom synthesis is available. Send your inquiries for more information. | London |
| Rivaroxaban EP Impurity I | An impurity of Rivaroxaban, a factor Xa (FXa) inhibitor used for the prevention and treatment of thromboembolic disorders. Group: Pharmaceutical. Alternative Names: 2-[2-[N-(5-Chlorothiophene-2-carbonyl)-4-[(5S)-5-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]anilino]ethoxy]acetic acid; Rivaroxaban Amine Impurity. CAS No. 1151893-81-0. Pack Sizes: 5 mg. Product ID: B0145-008649. Molecular formula: C24H21Cl2N3O7S2. Mole weight: 598.48. Custom synthesis is available. Send your inquiries for more information. | London |
| TG101348 | Fedratinib is a potent and selective JAK2 inhibitor with IC50 value of 6 nM. It also exhibits inhibitory effects against FLT3 (IC50 = 25 nM), RET (IC50 = 17 nM) and JAK3 (IC50 = 169 nM). Group: Pharmaceutical. Alternative Names: TG101348; TG 101348; TG-101348; SAR302503; SAR-302503; SAR 302503; Fedratinib; N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide. CAS No. 936091-26-8. Pack Sizes: 25 mg. Product ID: B0084-100796. Molecular formula: C27H36N6O3S. Mole weight: 524.68. Custom synthesis is available. Send your inquiries for more information. | London |
| XMD16-5 | XMD16-5is a novel non-receptor tyrosine kinase TNK2 inhibitor (IC50 = 16 nM and 77 nM for D163E and R806Q mutant TNK2, respectively). Group: Pharmaceutical. Alternative Names: 2-[4-(4-hydroxypiperidin-1-yl)anilino]-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one; XMD-16-5; XMD 16-5; XMD165; XMD-165; XMD 165. CAS No. 1345098-78-3. Pack Sizes: 50 mg. Product ID: B0084-007715. Molecular formula: C23H24N6O2. Mole weight: 416.48. Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
