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| Product | Description | |
|---|---|---|
| 16-Dehydropregnenolone acetate | 16-Dehydropregnenolone acetate is an impurity of Abiraterone, which is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: Dehydropregnenolone acetate; 16,17-Didehydropregnenolone acetate. CAS No. 979-02-2. Pack Sizes: 25 g. Product ID: NP6241. Molecular formula: C23H32O3. Mole weight: 356.51. Custom synthesis is available. Send your inquiries for more information. |  London |
| 3-Deoxy-3-acetyl abiraterone-3-ene | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 1-((8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl)ethanone. Pack Sizes: 10 mg. Product ID: B0038-007224. Molecular formula: C26H31NO. Mole weight: 373.54. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Deoxy 3-chloroabiraterone | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-((8R,9S,10R,13S,14S)-3-Chloro-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Pack Sizes: 10 mg. Product ID: B0038-007226. Molecular formula: C24H30ClN. Mole weight: 367.95. Custom synthesis is available. Send your inquiries for more information. | London |
| 9(10)-Dehydronandrolone | 9(10)-Dehydronandrolone, a synthetic androgen and anabolic steroid, plays a crucial role in managing hormone-related ailments. Its main function lies in fostering muscle growth and development among individuals suffering from muscle-wasting conditions, thereby showcasing its significance in the medical realm. Group: Pharmaceutical. CAS No. 6218-29-7. Pack Sizes: 1mg;1g;10g. Product ID: 6218-29-7. Molecular formula: C18H24O2. Mole weight: 272.39. Custom synthesis is available. Send your inquiries for more information. | London |
| ABC34 | ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). Group: Pharmaceutical. Alternative Names: 1,3-dioxo-7-(4-phenoxybenzyl)hexahydroimidazo[1,5-a]pyrazin-2(3H)-yl 4-(4-methoxyphenyl)piperazine-1-carboxylate. CAS No. 1831135-56-8. Pack Sizes: 1mg;1g;10g. Product ID: 1831135-56-8. Molecular formula: C31H33N5O6. Mole weight: 571.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone | Abiraterone blocks the synthesis of androgens by inhibiting CYP17A1. It is used to treat metastatic, castration-resistant prostate cancer. Uses: The treatment of metastatic, castration-resistant prostate cancer. Group: Pharmaceutical. Alternative Names: (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol; 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol; CB 7598; CB-7598; CB7598. CAS No. 154229-19-3. Pack Sizes: 5 g. Product ID: B0084-059670. Molecular formula: C24H31NO. Mole weight: 349.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone acetate | The acetate form of abiraterone, which blocks the synthesis of androgens by inhibiting CYP17A1. It can be used to treat metastatic, castration-resistant prostate cancer. Uses: The treatment of metastatic, castration-resistant prostate cancer. Group: Pharmaceutical. Alternative Names: CB7630; Zytiga; CB-7630; CB7630; Abiraterone (acetate). CAS No. 154229-18-2. Pack Sizes: 10 g. Product ID: NP3330. Molecular formula: C26H33NO2. Mole weight: 391.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone Acetate-5,6-Epoxide | Abiraterone Acetate-5,6-Epoxide is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Group: Pharmaceutical. Alternative Names: (3S,4aR,5aS,6aS,6bS,9aS,11aS,11bR)-9a,11b-dimethyl-9-(pyridin-3-yl)-1,2,3,4,5a,6,6a,6b,7,9a,10,11,11a,11b-tetradecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxiren-3-yl acetate; (3β,5α,6α)-5,6-epoxy-17-(3-pyridinyl)-3-androst-16-en-3-ol-3-acetate. CAS No. 1868064-50-9. Pack Sizes: 1mg;1g;10g. Product ID: 1868064-50-9. Molecular formula: C26H33NO3. Mole weight: 407.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone Acetate N-Oxide | Abiraterone Acetate N-Oxide is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Group: Pharmaceutical. Alternative Names: 3-((3S,8R,9S,10R,13S,14S)-3-acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine 1-oxide. CAS No. 2517964-85-9. Pack Sizes: 1mg;1g;10g. Product ID: 2517964-85-9. Molecular formula: C26H33NO3. Mole weight: 407.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone Ethyl Ether | Abiraterone Ethyl Ether is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Group: Pharmaceutical. Alternative Names: 3-((3S,8R,9S,10R,13S,14S)-3-ethoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. CAS No. 2484719-14-2. Pack Sizes: 1mg;1g;10g. Product ID: 2484719-14-2. Molecular formula: C26H35NO. Mole weight: 377.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone isopropyl ether | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-[3-(1-Methylethoxy)androsta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. CAS No. 2484719-15-3. Pack Sizes: 1mg;1g;10g. Product ID: 2484719-15-3. Molecular formula: C27H37NO. Mole weight: 391.59. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone Methyl Ether | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-[(3β)-3-Methoxyandrosta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. CAS No. 1470276-23-3. Pack Sizes: 1mg;1g;10g. Product ID: 1470276-23-3. Molecular formula: C25H33NO. Mole weight: 363.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone O-β-D-glucuronide | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: Abiraterone O-beta-D-glucuronide; (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol β-D-Glucuronide. CAS No. 2307194-33-6. Pack Sizes: 1mg;1g;10g. Product ID: 2307194-33-6. Molecular formula: C30H39NO7. Mole weight: 525.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone Related Compound 4 (Prasterone Acetate Triflate) | An impurity of Abiraterone, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. Group: Pharmaceutical. Alternative Names: Abiraterone Impurity 4, Prasterone Acetate Triflate. CAS No. 115375-60-5. Pack Sizes: 1mg;1g;10g. Product ID: 115375-60-5. Molecular formula: C22H29F3O5S. Mole weight: 462.53. Custom synthesis is available. Send your inquiries for more information. | London |
| AG-879 | AG-879, a tyrphostin compound, is a dual EGFR/HER2 inhibitor that was administered together with androgen withdrawal therapy. It inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM), and the VEGF receptor FLK1 (IC50 = ~1 μM). Group: Pharmaceutical. Alternative Names: α-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide. CAS No. 148741-30-4. Pack Sizes: 20 mg. Product ID: B0084-195953. Molecular formula: C18H24N2OS. Mole weight: 316.5. Custom synthesis is available. Send your inquiries for more information. | London |
| AMI-1 | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Group: Pharmaceutical. Alternative Names: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. CAS No. 20324-87-2. Pack Sizes: 50 mg. Product ID: B2693-087022. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. Custom synthesis is available. Send your inquiries for | London |
| Anhydro abiraterone | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-Androsta-3,5,16-trien-17-yl-pyridine; 3-((8R,9S,10R,13S,14S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine; 17-(3-Pyridyl)androsta-3,5,16-triene. CAS No. 154229-20-6. Pack Sizes: 10 mg. Product ID: B0038-007225. Molecular formula: C24H29N. Mole weight: 331.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Apalutamide | Apalutamide is a potent and competitive androgen receptor (AR) antagonist with potential antineoplastic activity. It binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. Group: Pharmaceutical. Alternative Names: ARN-509; Apalutamide; ARN 509; JNJ56021927; JNJ-56021927; JNJ 56021927; ARN509. CAS No. 956104-40-8. Pack Sizes: 100 mg. Product ID: B0084-462663. Molecular formula: C21H15F4N5O2S. Mole weight: 477.43. Custom synthesis is available. Send your inquiries for more information. | London |
| ARD-2128 | ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor degrader. It effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. Group: Pharmaceutical. Alternative Names: ARD2128; ARD 2128; N-[(1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]piperidin-4-yl]methyl]piperazin-1-yl]benzamide. CAS No. 2222111-87-5. Pack Sizes: 25 mg. Product ID: B1370-380960. Molecular formula: C45H50ClN7O6. Mole weight: 820.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Carbazole derivative 1 | Carbazole derivative 1 is a carbazole derivative with the effect to reduce androgen or oestrogen levels in mammals. Group: Pharmaceutical. Alternative Names: 2-fluoro-7-(pyridin-3-ylmethyl)-9H-carbazoleCarbazole derivative; 1164914-28-7; SCHEMBL9030564HY-U00323. CAS No. 164914-28-7. Pack Sizes: 1mg;1g;10g. Product ID: 164914-28-7. Molecular formula: C18H13FN2. Mole weight: 276.31. Custom synthesis is available. Send your inquiries for more information. | London |
| (-)-Catechin gallate | (-)-Catechin gallate, a minor polyphenolic constituent in green tea, is used to study its cytotoxicity. It enhances Fe(2+)-induced, lipid peroxidation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cancer. Uses: (-)-catechin gallate has been found to be probably effective in restraining tyrosine phosphorylation caused by vegf and have potential activity in the study of breast cancer. Group: Pharmaceutical. Alternative Names: (-)-CG; (-)-Catechin gallate; (2S,3R)-2-(3,4-Dihydroxyphenyl)-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-5,7-diol; 3,4,5-Trihydroxybenzoic acid [[(2S)-2β-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran]-3α-yl] ester. CAS No. 130405-40-2. Pack Sizes: 25 mg. Product ID: B2703-464825. Molecular formula: C22H18O10. Mole weight: 442.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Cortexolone 17 alpha-propionate | Cortexolone 17 alpha-propionate, also called as CB-03-01, belonging to the family of ester derivatives of cortexolone, is a potent and topical and peripherally selective steroid antagonist of androgen. Group: Pharmaceutical. Alternative Names: CB-03-01; CB 03-01; CB03-01; [(8R,9S,10R,13S,14S,17R)-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoateCB-03-01cortexolone 17alpha-propionate. CAS No. 19608-29-8. Pack Sizes: 1 g. Product ID: B2693-454554. Molecular formula: C24H34O5. Mole weight: 402.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Cyproterone acetate | Cyproterone acetate is a synthetic derivative of 17-hydroxyprogesterone, and acts as an androgen receptor antagonist as well as a weak progesterone receptor agonist with weak progestational and glucocorticoid activity. Uses: Androgen antagonists; antineoplastic agents; contraceptive agents, male; progestational hormones, synthetic. Group: Pharmaceutical. Alternative Names: Androcur, Cyprostat,Cyproteron, Procur, Cyprone, Cyprohexal, Ciproterona, Cyproteronum, Neoproxil, Siterone. CAS No. 427-51-0. Pack Sizes: 1mg;1g;10g. Product ID: NP3299. Molecular formula: C24H29ClO4. Mole weight: 416.93766. Custom synthesis is available. Send your inquiries for more information. | London |
| Enzalutamide | Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM. It inhibits the activity of prostate cancer cell Ars, which over expressed in prostate cancer. Uses: Potential antineoplastic agent. Group: Pharmaceutical. Alternative Names: MDV3100; MDV 3100; MDV-3100; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide; Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methyl-; 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide; S-Enzalutamide; Xtandi. CAS No. 915087-33-1. Pack Sizes: 500 mg. Product ID: B0084-155497. Molecular formula: C21H16F4N4O2S. Mole weight: 464.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Galloylpaeoniflorin | 6'-O-Galloylpaeoniflorin is a natural monoterpenoid compound isolated from the roots of Paeonia lactiflora Pall. 6'-O-Galloylpaeoniflorin exhibits strong androgen receptor (AR) binding activity. Group: Pharmaceutical. Alternative Names: β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-(3,4,5-trihydroxybenzoate); β-D-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-(3,4,5-trihydroxybenzoate), [1aR-(1aα,2β,3aα,5α,5aα,5bα)]-; 6'-O-Galloyl paeoniflorin; ((2R,3S,4S,5R,6S)-6-(((1aR,1a1S,2R,3aR,5S,5aR)-1a1-((Benzoyloxy)methyl)-2-hydroxy-5-methyltetrahydro-1H-3,4-dioxa-2,5-methanocyclobuta[cd]pentalen-5a(5H)-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl 3,4,5-trihydroxybenzoate. CAS No. 122965-41-7. Pack Sizes: 5 mg. Product ID: NP4524. Molecular formula: C30H32O15. Mole weight: 632.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Ganoderol B | Ganoderol B also called ganodermadiol is a natural triterpenoid found in the fruiting body of Ganoderma lucidum, it is an angiotensin-converting enzyme inhibitor and is a potent α-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidum. Ganoderol B exhibits the activity of anti-androgen. Uses: Anti-androgen. Group: Pharmaceutical. Alternative Names: (3beta,24E)-Lanosta-7,9(11),24-trien-3,26-diol;ganodermadiol;(24E)-5α-Lanosta-7,9(11), 24-triene-3β,26-diol. CAS No. 104700-96-1. Pack Sizes: 5 mg. Product ID: NP6278. Molecular formula: C30H48O2. Mole weight: 440.7. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-2881078 | GSK-2881078, an indole derivative, has been found to be an androgen receptor modulator that could probably be effective against Cachexia. It is still under Phase I trail. Uses: Anabolic agents. Group: Pharmaceutical. Alternative Names: GSK 2881078; GSK2881078; CS-5736; (R)-1-(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile. CAS No. 1539314-06-1. Pack Sizes: 25 mg. Product ID: B2693-475855. Molecular formula: C14H13F3N2O2S. Mole weight: 330.33. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Enzalutamide | N-desmethyl Enzalutamide is a major metabolite of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist (IC50 = 36 nM) in LNCaP cells that inhibits the transcriptional activity of a mutant AR protein. Enzalutamide resists against induction of prostate-specific antigen (PSA) and transmembrane serine protease 2 (TMPRSS2). N-desmethyl Enzalutamide can be used for the treatment of disorders involving androgen, estrogen and progesterone receptors. Uses: The treatment of disorders involving androgen, estrogen and progesterone receptors. Group: Pharmaceutical. Alternative Names: N-desmethylenzalutamide; 1242137-16-1; 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzamide; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzamide; Enzalutamide metabolite. CAS No. 1242137-16-1. Pack Sizes: 20 mg. Product ID: B0084-474425. Molecular formula: C20H14F4N4O2S. Mole weight: 450.412. Custom synthesis is available. Send your inquiries for more information. | London |
| Nestoron | Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It does not bind to the estrogen receptor either, but it has some affinity for the glucocorticoid receptor. It appears to act as an agonist, but it does not appear to produce any glucocorticoid side effects unless used at high doses. It has been shown to have neurogenic and neuroprotective activity. It holds back proinflammatory mediators and neuropathology in the wobbler mouse model of motoneuron degeneration. It protected against hippocampus abnormalities and improved functional outcomes of EAE mice, which suggests its potential value. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. Uses: Nestorone is used as a hormonal contraceptive in several south american countries. it has been used as a female contraceptive and may be useful as a male contraceptive too recently. it lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. Group: Pharmaceutical. Alternative Names: ST-1435; ST1435; ST1435; Elcometrine; Nestorone; segesterone acetate; 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,2 | London |
| Nilutamide | Nilutamide is a non-steroidal and silent antiandrogen that binds to androgen receptors and also inhibits androgen biosynthesis in vitro. In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: Anandron; Nilandron; 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione. CAS No. 63612-50-0. Pack Sizes: 10 g. Product ID: B2693-465325. Molecular formula: C12H10F3N3O4. Mole weight: 317.224. Custom synthesis is available. Send your inquiries for more information. | London |
| ODM-201 | ODM-201 is a new-generation, potent and selective androgen receptor (AR) inhibitor which is potential useful for treatment of castration-resistant prostate cancer (CRPC). ODM-201 is a full and high-affinity AR antagonist that, similar to second-generation antiandrogens enzalutamide and ARN-509, inhibits testosterone-induced nuclear translocation of AR. Group: Pharmaceutical. Alternative Names: ODM-201; ODM 201; ODM201. CAS No. 1297538-32-9. Pack Sizes: 100 mg. Product ID: B0084-470833. Molecular formula: C19H19ClN6O2. Mole weight: 389.85. Custom synthesis is available. Send your inquiries for more information. | London |
| ORM-15341 | ORM-15341, an androgen receptor antagonist, have potential effect against prostate cancer and is commonly found as an active main metabolite of ODM-201. IC50 = 38 nM. Group: Pharmaceutical. Alternative Names: CS-5191; ORM 15341; CS 5191; ORM15341; CS5191. CAS No. 1297537-33-7. Pack Sizes: 50 mg. Product ID: B2693-474454. Molecular formula: C19H17ClN6O2. Mole weight: 396.83. Custom synthesis is available. Send your inquiries for more information. | London |
| Ozarelix acetate | Ozarelix is a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Group: Pharmaceutical. Alternative Names: D-63153 acetate; D 63153 acetate; D63153 acetate. CAS No. 896710-46-6. Pack Sizes: 10 mg. Product ID: BAT-016128. Molecular formula: C74H100ClN17O16. Mole weight: 1519.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Psoralidin | Psoralidin is a furanocoumarin natural product used in Chinese medicine. Psoralidin, a PTP1B inhibitor, has been shown to have anticancer activity with a variety of mechanisms proposed. Psoralidin induces ROS generation in androgen-independent prostate cancer cells, leading to inhibition of cell proliferation. Psoralidin has been found to downregulate NOTCH1 signaling, causing growth arrest in both breast cancer stem cells and breast cancer cells. Uses: Anticancer and chemopreventive properties. Group: Pharmaceutical. Alternative Names: 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one; 3,9-Dihydroxy-2-prenylcoumestan. CAS No. 18642-23-4. Pack Sizes: 25 mg. Product ID: NP1133. Molecular formula: C20H16O5. Mole weight: 336.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Pyrvinium pamoate | Pyrvinium pamoate, a nonabsorbed anthelmintic drug, is a potent androgen receptor inhibitor and a selective WNT pathway inhibitor. Pyrvinium pamoate is a potential drug candidate for the treatment of cryptosporidiosis in both immunocompetent and immunocompromised individuals. Uses: Anthelmintics. Group: Pharmaceutical. Alternative Names: VPC-14337; VPC 14337; VPC14337; 6-(Dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-4,4'-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (2:1)-quinolinium; Alnoxin; Altolat; NSC 223622; PP; Pamovin; Vermitibier; Vipyrvinium embonate. CAS No. 3546-41-6. Pack Sizes: 100 mg. Product ID: B2693-111705. Molecular formula: C26H28N3.1/2C23H14O6. Mole weight: 575.7. Custom synthesis is available. Send your inquiries for more information. | London |
| Relugolix | Relugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH) receptor antagonist administered orally. By preventing LH-RH from binding with the LH-RH receptor in the anterior pituitary gland and suppressing the secretion of luteinizing hormone (LH) and follicle stimulation hormone (FSH) from the anterior pituitary gland, TAK-385 controls the effect of LH and FSH on the ovary, reduces the level of estrogen in blood, which is known to be associated with the development of endometriosis and uterine fibroids, and is expected to improve the symptoms of these disorders. Uses: Androgen antagonists. Group: Pharmaceutical. Alternative Names: TAK-385; N-[4-[1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-1,2,3,4-tetrahydro-3-(6-methoxy-3-pyridazinyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-N'-methoxyurea; Orgovyx; RVT 601; 1-{4-[1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea. CAS No. 737789-87-6. Pack Sizes: 10 mg. Product ID: B0084-462794. Molecular formula: C29H27F2N7O5S. Mole weight: 623.63. Custom synthesis is available. Send your inquiries for more information. | London |
| RU 58841 | RU 58841 is a new non-steroidal antiandrogen which has potential for use in treating androgen-dependent skin disorders such as acne, hirsutism and androgen-dependent alopecia. Group: Pharmaceutical. Alternative Names: RU-58841; RU58841; RU 58841; 4-(4,4-dimethyl-2,5-dioxo-3-(4-hydroxybutyl)-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile. CAS No. 154992-24-2. Pack Sizes: 5 g. Product ID: B2693-405991. Molecular formula: C17H18F3N3O3. Mole weight: 369.34. Custom synthesis is available. Send your inquiries for more information. | London |
| RU-59063 | RU-59063 is a nonsteroidal androgen or selective androgen receptor modulator (SARM). Group: Pharmaceutical. Alternative Names: RU 59063; 4-(3-(4-Hydroxybutyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile. CAS No. 155180-53-3. Pack Sizes: 50 mg. Product ID: B1370-303413. Molecular formula: C17H18F3N3O2S. Mole weight: 385.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Sitostenone | Sitostenone is isolated from the roots of Xanthium sibiricum. Sitostenone has antioxidant activity and can be used in the treatment of androgen-dependent diseases, especially benign prostatic hyperplasia. Group: Pharmaceutical. Alternative Names: Stigmast-4-en-3-one; (24R)-24-Ethylcholest-4-en-3-one; (24R)-Stigmast-4-en-3-one; 4-En-3-stigmastone; NSC 49082; β-Rosasterol oxide; β-Sitost-4-en-3-one; β-Sitostenone; Δ4-Sitosterol-3-one; beta-sitostenone. CAS No. 1058-61-3. Pack Sizes: 5 mg. Product ID: NP6070. Molecular formula: C29H48O. Mole weight: 412.69. Custom synthesis is available. Send your inquiries for more information. | London |
| (Z)-Guggulsterone | Z-Guggulsterone is a broad spectrum steroid receptor ligand that acts as a mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki = 37, 224 and 252 nM, respectively) and weak androgen receptor agonist (Ki = 315 nM). Z-Guggulsterone is also a selective antagonist of farnesoid X receptor (FXR) exhibiting antilipidemic, antiseptic, antirheumatic and anti-inflammatory activity in vivo. Group: Pharmaceutical. Alternative Names: (Z)-Guggulsterone;Z-Guggulsterone;Guggulsterone;39025-23-5;95975-55-6;Guggulsterones Z;Cis-Guggulsterone;Guggulsterone E&Z;GUGGULSTERONE Z;Guggulsterone, (Z)-;Z/E-Guggulsterone;(Z)-Pregna-4,17(20)-diene-3,16-dione;6CST3U34GN;DTXSID1033539;Pregna-4,17(20)-diene-3,16-dione, (17Z)-;Pregna-4,17(20)-diene-3,16-dione;(8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydroc. CAS No. 39025-23-5. Pack Sizes: 10 mg. Product ID: B2693-091575. Molecular formula: C28H22N6O3. Mole weight: 490.5. Custom synthesis is available. Send your inquiries for more information. | London |
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