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| Product | Description | |
|---|---|---|
| Amyl Acetate | Amyl Acetate - Amyl ethanoate - 3 methyl butyl acetate, Solvents. Mistral Industrial Chemicals our speciality is supplying Technical grade & Industrial grade chemicals in sizes from: 1Kg to 25Kg. We can also supply products in barrels & multiple bags / pallets. | Mistral Lab Supplies Northern Ireland |
| AMYL ACETATE | AMYL ACETATE, UK suppliers of laboratory chemicals and apparatus needed |  |
| Amylin (human) | Amylin, islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic β-cells. It inhibits insulin-stimulated glucose uptake, delays gastric emptying and promotes satiety. It has glucose lowering effects in vivo. It is also used to study the mechanisms of amyloid deposition and its role in molecular misfolding processes expecially in conditions such as diabetes type II. Group: Pharmaceutical. CAS No. 122384-88-7. Pack Sizes: 1 mg. Product ID: BAT-006084. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Amyloid β-peptide (1-42) human | Amyloid β-Peptide (12-28) (human), an Amyloid β-peptide fragment, binds with high affinity to α7-nicotinic ACh receptors. It impairs memory retention following central administration in mice. Uses: Implicated in alzheimer's disease. Group: Pharmaceutical. CAS No. 107761-42-2. Pack Sizes: 1 mg. Product ID: BAT-006074. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Amyloid beta-peptide (25-35) | Amyloid beta-peptide(25-35), the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, is functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease. Group: Pharmaceutical. CAS No. 131602-53-4. Pack Sizes: 10 mg. Product ID: BAT-010067. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Amyloid β-peptide (42-1) human | Amyloid β-peptide (42-1) (human), is the predominant form of amyloid β-peptide found in the brains of patients with Alzheimer's disease. Uses: Implicated in alzheimer's disease. Group: Pharmaceutical. CAS No. 317366-82-8. Pack Sizes: 10 mg. Product ID: BAT-010439. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1,3-dimethylamylamine | DMAA |  |
| 2,4-Di-tert-amylphenol | 500ml Pack Size. Group: Building Blocks, Organics, Phenols. Formula: C16H26O. CAS No. 120-95-6. Prepack ID : 90028488-500ml. Molecular Weight : 234.38. |  |
| 4-sec-Amylphenol | 4-sec-Amylphenol. Group: Pharmaceutical. CAS No. 25735-67-5. Pack Sizes: 100 mg. Product ID: BB054145. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| a-AMYLASE UN | α-Amylase UN, Suppliers in the UK wanted | |
| Abietic Acid Diamylamine | Abietic Acid Diamylamine. Group: Pharmaceutical. CAS No. 881185-17-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BB075643. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Abz-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (669-674)-EDDnp | Abz-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (669-674)-EDDnp is an intramolecularly quenched fluorescent substrate with the ortho-aminobenzoyl (Abz)/N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor/acceptor pair. It corresponds to the Swedish-mutated (JMV2236) β-amyloid precursor protein (βAPP) sequence, which is targeted by β-secretase BACE (β-site APP-cleaving activity). It is more selectively cleaved by BACE1 and BACE2 than by cathepsin D, a disintegrin and metalloprotease 10 (ADAM10), tumor necrosis α-converting enzyme (TACE), presenilin-1 (PS1), or presenilin-2 (PS2). Group: Pharmaceutical. CAS No. 1007306-20-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014531. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-Amylin (8-37) (human) | Acetyl-Amylin (8-37) (human) is a most effective amylin antagonist, but its ability to block CGRP inhibition is limited. It completely reverses the inhibitory effect of IAPP on 14C-glycogen accumulation in vitro. Group: Pharmaceutical. CAS No. 178603-79-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015123. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-Amyloid β-Protein (1-6) amide | Experiments using sub-peptides of Aβ42 show that the epitope identified by antibody A8 is located in the 1-6 region of A&beta. Group: Pharmaceutical. CAS No. 903883-22-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014844. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide | Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide is a membrane-permeable inhibitor of Aβ (1-40) fibrillogenesis. Group: Pharmaceutical. CAS No. 461640-33-5. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015390. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide | Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide is an analog of product H-4876 with small chemical modifications which enhance its stability against proteolytic degradation. It is a β-sheet breaker peptide that crosses the blood-brain barrier faster than most known proteins and peptides selectively absorbed by the brain, so it is assumed that the peptide is specifically transported to the brain. Group: Pharmaceutical. CAS No. 339990-02-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015329. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Alpha Amylase - From Malt | Alpha Amylase - From Malt. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 9000-90-2. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| alpha-Amylase, heat-stable | 5g Pack Size. Group: Analytical Reagents, Biochemicals, Catalysts. CAS No. 9000-85-5. Prepack ID : 90005082-5g. | |
| α-Amyloid Precursor Protein Modulator | α-Amyloid Precursor Protein Modulator is a cell-permeable protein kinase C (PKC) activator. It was shown to induce differentiation of hESCs into Pdx-1 expressing pancreatic progenitor cells. Group: Pharmaceutical. CAS No. 497259-23-1. Pack Sizes: 2.5 mg. Product ID: B0084-314011. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| β-Amyloid (1-40) | Amyloid β-Peptide (1-40) (human) is a 40-residue protein fragment of the C-terminal portion of the β-amyloid protein, which is found in plaques in the brains of patients with Alzheimer's disease. It is neurotrophic and neurotoxic in vivo and in vitro in human and rat neuronal cell cultures. It prevented neuronal cell death by inhibiting fibril formation when administered concurrently with Aβ (1-42) in rat cortical cultures at 3 μM. It prevented neuronal damage when injected into rat entorhinal cortex with Aβ (1-42) both at 400 μM. Group: Pharmaceutical. CAS No. 131438-79-4. Pack Sizes: 2.5 mg. Product ID: BAT-006075. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biotiin-Amylin, human amidated | Biotiin-Amylin, human amidated. Group: Pharmaceutical. CAS No. 1678415-18-3. Pack Sizes: 1 mg. Product ID: BAT-006255. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cinnamyl chloride | 100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C9H9Cl. CAS No. 2687-12-9. Prepack ID : 19662438-100g. Molecular Weight : 152.62. | |
| Dimethylamylamine | 1g Pack Size. Group: Amines, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C7H17N. CAS No. 105-41-9. Prepack ID : 90004722-1g. Molecular Weight : 115.22. | |
| Isoamyl acetate | 100g Pack Size. Group: Aroma Chemicals, Biochemicals, Building Blocks, Flavours and Fragrance Materials, Organics. Formula: C7H14O2. CAS No. 123-92-2. Prepack ID : 89968167-100g. Molecular Weight : 130.18. | |
| Iso Amyl Acetate | Iso Amyl Acetate Uses: Pharmaceutical Research and Development. Group: Special Esters. CAS No. 123-92-2. Pack Sizes: 180kg drums & IBC's. Categories: NORDMANN Key intermediates and specialty chemicals. |  UK / EU / USA / Japan |
| Iso-Amyl Acetate | Iso-Amyl Acetate. At Tan International we supply a wide range of products covering all industry sectors |  Scotland |
| ISO AMYL ALCOHOL | ISO AMYL ALCOHOL, Suppliers of UK laboratory chemicals wanted | |
| Isoamyl alcohol FG | Isoamyl alcohol FG. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 123-51-3. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. | Cenik Chemicals |
| Isoamyl nitrite | 100g Pack Size. Group: Building Blocks, Organics. Formula: (CH3)2CHCH2CH2ONO. CAS No. 110-46-3. Prepack ID : 89967044-100g. Molecular Weight : 117.15. | |
| Isoamyl Nitrite | Isoamyl Nitrite. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 110-46-3. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. | Cenik Chemicals |
| Mecamylamine hydrochloride | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C11H21N · HCl. CAS No. 826-39-1. Prepack ID : 21592353-100mg. Molecular Weight : 203.75. | |
| N-Carbamyl-L-Glutamic Acid (NCG) | Nutritional booster that has been shown to significantly increase muscle production and is used in many popular bodybuilding muscle growth products. Uses: Dietary supplement. Group: Dietary supplements. CAS No. 1188-38-1. |  |
| N-(gamma-Glutamyl)ethanolamine | N-(gamma-Glutamyl)ethanolamine is a derivative of glutamine. Group: Pharmaceutical. CAS No. 2650-74-0. Pack Sizes: 100 mg. Product ID: BAT-014378. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-L-γ-glutamyl-L-tyrosine | N-L-γ-glutamyl-L-tyrosine is a dipeptide produced by the catabolism of proteins. Group: Pharmaceutical. CAS No. 7432-23-7. Pack Sizes: 1 g. Product ID: BAT-015508. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| tert-Amyl alcohol | tert-Amyl alcohol Uses: Pharmaceutical R&D. Group: Chemicals & Intermediates. CAS No. 75-85-4. Pack Sizes: 160kg Drums. Categories: NORDMANN Key intermediates and specialty chemicals suppliers. | UK / EU / USA / Japan |
| Tert Amyl Alcohol in 160kg nett drums | Tert Amyl Alcohol in 160kg nett drums. At Tan International we supply a wide range of products covering all industry sectors | Scotland |
| tert-Amylamine | tert-Amylamine Uses: Pharmaceutical R&D. Group: Amines. CAS No. 594-39-8. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals suppliers (Formerly Melrob-Eurolabs). | UK / EU / USA / Japan |
| 2-Methyl-2-butanol | 2-Methyl-2-butanol; 98%. Group: Organics. CAS No. 75-85-4. Pack Sizes: 1kg; 5kg; 25kg; 100kg; 200kgs. Product ID: AB117840. Categories: 2-methyl-2-butanol; tert-amyl alcohol. |  |
| 4-[[4-[[4-(2,2,2-Trifluoroethoxy)-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxane-4-carboxylic acid | 4-[[4-[[4-(2,2,2-Trifluoroethoxy)-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxane-4-carboxylic acid, a potent remedy for Alzheimer's disease, operates via focusing on beta-amyloid plaques, an established sign of the disease. The potential outcome of this product is to decelerate or bring to a standstill the progress of the disease, subsequently enhancing patients' quality of life. Group: Pharmaceutical. CAS No. 907607-22-1. Pack Sizes: 100 mg. Product ID: B2699-075069. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4',5'-Dibromofluorescein octadecyl ester | 4',5'-Dibromofluorescein octadecyl ester, a fluorescent dye that serves as a lipophilic tracer, is increasingly prevalent in the biomedical industry, specifically for its in vitro lipid droplet detection capabilities. Furthermore, it has been valuable in Alzheimer's disease research as a diagnostic tool due to its proficiency in binding to amyloid beta plaques within the brain. Such versatile applications highlight the diverse potential and significance of this highly specialized dye. Group: Pharmaceutical. CAS No. 138833-47-3. Pack Sizes: 1 g. Product ID: B1370-111065. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-(p-Toluidino)-2-naphthalenesulfonic acid sodium salt | 6-(p-Toluidino)-2-naphthalenesulfonic acid sodium salt, a fluorescent probe with a high degree of perplexity and burstiness, is extensively utilized for detecting proteins and nucleic acids in biomedical research. Due to its exceptional burstiness, this probe is remarkably effective in identifying amyloid fibrils, particularly those linked to neurodegenerative illnesses, including Alzheimer's and Huntington's disease. Group: Pharmaceutical. CAS No. 53313-85-2. Pack Sizes: 100 mg. Product ID: B1370-189502. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC 187 | AC 187 is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo. Group: Pharmaceutical. CAS No. 151804-77-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-010348. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC 187 acetate | AC 187 acetate is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels, and increases food intake in vivo. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016307. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Nle-Pro-Nle-Asp-AMC | Ac-Nle-Pro-Nle-Asp-AMC is a substrate for proteasomes. It can be cleaved by the caspase-like site of proteasome, also known as postglutamyl peptide hydrolase (PGPH). AMC (7-amino-4-methylcoumarin) is released and produces the fluorescence utilized to quantify the caspase-like site activity. Ac-Nle-Pro-Nle-Asp-AMC also inhibits the chymotrypsin-like activity of the proteasome allosterically when bound to the caspase-like site. Group: Pharmaceutical. CAS No. 355140-49-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015113. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Butylphthalide (Natural) | Butylphthalide is an anti-cerebral-ischemia drug, which is first isolated from the seeds of celery, showed efficacy in animal models of stroke. It alleviates oxidative stress caused by chronic cerebral ischemia, improves cholinergic function, and inhibits amyloid beta accumulation, thereby improving cerebral neuronal injury and cognitive deficits. Uses: Antihypertensive;anti-cerebral-ischemia. Group: Pharmaceutical. CAS No. 6066-49-5. Pack Sizes: 50 mg. Product ID: B0005-464370. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cyclocephaloside II | Cyclocephaloside II - a natural remedy with immense potential for use in treating Alzheimer's disease. Its efficacy lies in its role as an effective inhibitor of amyloid beta peptides. These peptides are widely believed to play a pivotal part in the neural degradation characteristic of Alzheimer's disease. In addition, studies have indicated that Cyclocephaloside II possesses antioxidant and anti-inflammatory properties, which may grant it protective effects against the ravages of oxidative stress within the brain. Group: Pharmaceutical. CAS No. 215776-78-6. Pack Sizes: 5 mg. Product ID: B0005-465738. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Deoxynojirimycin | Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase. Group: Pharmaceutical. CAS No. 19130-96-2. Pack Sizes: 250 mg. Product ID: BBF-01829. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| EUK 134 | EUK-134 is a unique small molecule antioxidant and anti-aging active substance with excellent antioxidant properties. It possesses the dual effects of superoxide dismutase SOD and catalase CAT, effectively improving cell damage caused by oxidative stress, and inhibiting the formation of β-amyloid protein and related amyloid protein fibers. The EUK-134 facilitates the penetration and absorption of the skin surface, enabling direct entry into the skin to exert its effects and optimize its potent efficacy. Essentially functioning as a catalyst, it remains unaffected by the number of reactions, allowing for reusability with minimal quantity while maintaining stability in nature. It can be used in anti-aging products, sunscreen products, whitening products and skin repair products. Group: Pharmaceutical. CAS No. 81065-76-1. Pack Sizes: 100 mg. Product ID: B2693-098846. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| FLI-06 | FLI-06 is a Notch inhibitor that disrupts Notch trafficking and processing and reduces amyloid β secretion. It was shown to suppress proliferation and induce apoptosis and cell cycle arrest by targeting LSD1 and Notch pathway in esophageal squamous cell carcinoma cells. Group: Pharmaceutical. CAS No. 313967-18-9. Pack Sizes: 50 mg. Product ID: B2693-286397. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Galantamine hydrobromide | Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. Uses: Nootropic agents. Group: Pharmaceutical. CAS No. 1953-4-4. Pack Sizes: 500 mg. Product ID: NP0561. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glutathione EP Impurity C | Oxiglutatione is a stabilized formulation of disodium glutathione disulfide (GSSG; oxidized glutathione) and cisplatin (1000:1) with potential chemoprotective and immunomodulating activities. Mimicking endogenous GSSG, Oxiglutatione acts as a competitive substrate for gamma-glutamyl-transpeptidase (GGT), which may result in the S-glutathionylation of proteins, predominantly actin, a redox stress on endoplasmic reticulum (ER), and ER stress-induced apoptosis. S-glutathionylation may be stimulated by reactive oxygen species (ROS) liberated by an oxiglutatione-induced increase in GGT activity. Oxiglutatione may also induce phosphorylation of proteins such as ERK and p38, two kinases that play critical regulatory roles in cell proliferation and apoptosis. The cisplatin component of this agent does not provide an effective therapeutic concentration of cisplatin in vivo. Group: Pharmaceutical. CAS No. 27025-41-8. Pack Sizes: 25 g. Product ID: B0084-064728. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Golotimod | Golotimod is an orally bioactive synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities. Golotimod has been shown to inhibit the expression of STAT-3, reversing immunosuppression and stimulating an anti-tumor immune response. It may stimulate the production of T-lymphocytes (in particular the helper T [Th1] cells), activate macrophages, and increase levels of interleukin 2 and interferon gamma. Group: Pharmaceutical. CAS No. 229305-39-9. Pack Sizes: 50 mg. Product ID: BAT-010153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hexadecanal | Hexadecanal is a fatty aldehyde used in the pharmaceutical industry as an intermediate in the production of various drugs. It is also used in research studies on Alzheimer's disease to investigate its effects on amyloid-beta aggregation. Uses: It is used in the production of lipid and fatty acids. Group: Pharmaceutical. CAS No. 629-80-1. Pack Sizes: 25 g. Product ID: B1370-030523. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ISRIB | ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Group: Pharmaceutical. CAS No. 1597403-47-8. Pack Sizes: 250 mg. Product ID: BAT-010737. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ISRIB (mix-Isomer) | ISRIB (mix-Isomer), is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Group: Pharmaceutical. CAS No. 548470-11-7. Pack Sizes: 25 mg. Product ID: BAT-010736. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ixazomib Citrate | The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Group: Pharmaceutical. CAS No. 1239908-20-3. Pack Sizes: 100 mg. Product ID: BBF-04173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Myricetin | Myricetin is a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, which has antioxidant and anti tumor properties. Studies shows that high myricetin consumption reduces the risk of prostate cancer and pancreatic cancer. Myricetin has the effect of whitening skin, it is a good functional cosmetics material. Uses: Anti-hiv; anti-tumor; anti-amyloidogenic activity. Group: Pharmaceutical. CAS No. 529-44-2. Pack Sizes: 100 g. Product ID: NP1894. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-(4-Nitrophenyl)-L-glutamine | N-(4-Nitrophenyl)-L-glutamine is a substrate for γ-glutamyltransferase (GGT), which is an important enzyme with wide applications in biocatalysis and clinical diagnosis. Group: Pharmaceutical. CAS No. 7300-59-6. Pack Sizes: 100 g. Product ID: BAT-002168. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-hydroxypipecolic acid | N-Hydroxypipecolic acid, a pivotal biochemical component of drug synthesis for treatment of Alzheimer's and other neurodegenerative diseases, remarkably inhibits gamma-secretase enzyme leading to decreased amyloid beta production, a hallmark of Alzheimer's. Group: Pharmaceutical. CAS No. 115819-92-6. Pack Sizes: 100 mg. Product ID: B2699-229217. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Patisiran Sodium | Patisiran sodium is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran sodium specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran sodium can be used for the research of hereditary TTR amyloidosis. Group: Pharmaceutical. CAS No. 1386913-72-9. Pack Sizes: 5 mg. Product ID: B1370-072715. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Physostigmine salicylate | Physostigmine salicylate is a cholinesterase inhibitor that can cross blood-brain barrier. It forms slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). It has been used to improve cognitive ability and treat glaucoma. Group: Pharmaceutical. CAS No. 57-64-7. Pack Sizes: 250 mg. Product ID: B0084-028331. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PMX 205 | PMX 205 is a potent C5a receptor peptide antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Group: Pharmaceutical. CAS No. 514814-49-4. Pack Sizes: 10 mg. Product ID: BAT-010103. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pramlintide acetate hydrate | Pramlintide is an analog of amylin, an antidiabetic peptide hormone released into the bloodstream. It has been used in the treatment of diabetes. Group: Pharmaceutical. CAS No. 196078-30-5. Pack Sizes: 5 mg. Product ID: BAT-010155. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Prionidipene A | Prionidipene A, a promising chemical compound, exhibits therapeutic potential in treating neurological disorders including Alzheimer's disease. This inhibitor of the beta-site amyloid precursor protein cleaving enzyme curtails the production of amyloid beta peptides, an established hallmark of Alzheimer's disease. Interestingly, research proposes that Prionidipene A reduces amyloid beta levels in the brain, which in turn has therapeutic implications. Moreover, improved cognitive function was noted, suggesting that this compound could be a pivotal stepping stone in developing novel therapeutics for Alzheimer's disease. Group: Pharmaceutical. CAS No. 2199455-72-4. Pack Sizes: 5 mg. Product ID: NP1630. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| [Pyr1]-Apelin-13 | [Pyr1]-Apelin-13 is the highly potent pyroglutamylated form of apelin-13, which is an endogenous ligand of the G protein-coupled APJ receptor with EC50 value of 0.37 nM. It is the major apelin form in human plasma and heart, which the N-terminal glutamine residue is cyclized to pyroglutamic acid. It exhibits higher APJ agonist potency than Apelin-13. It has antipyretic and vasoconstrictor effects in vitro and in vivo. It is widely used for studying APJ-mediated cellular and physiological functions both in cultures and in animals in vivo. It is reactive toward human, rat, bovine and murine species. Group: Pharmaceutical. CAS No. 217082-60-5. Pack Sizes: 2.5 mg. Product ID: BAT-006078. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rosarin | Rosarin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. It exhibits anti-inflammatory and neuroprotective effects. Group: Pharmaceutical. CAS No. 84954-93-8. Pack Sizes: 25 mg. Product ID: B2703-465568. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rosavin | Rosavin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. It exhibits antidepressant and anxiolytic activity. Uses: Antidepressant and anxiolytic. Group: Pharmaceutical. CAS No. 84954-92-7. Pack Sizes: 50 mg. Product ID: B2703-465127. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| RTA-408 | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Group: Pharmaceutical. CAS No. 1474034-05-3. Pack Sizes: 20 mg. Product ID: B0084-462776. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Spinosin | Spinosin ameliorated memory impairment induced through AβO, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. Therefore, Spinosin might be a useful agent against the amyloid b protein-induced cognitive dysfunction observed in AD patients. Uses: Anxiolytic. Group: Pharmaceutical. CAS No. 72063-39-9. Pack Sizes: 20 mg. Product ID: NP1925. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tafamidis | Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. It is a drug for the amelioration of transthyretin-related hereditary amyloidosis. It functions by kinetic stabilization of the correctly folded tetrameric form of the transthyretin (TTR) protein and binds selectively and with negative cooperativity to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR. Group: Pharmaceutical. CAS No. 594839-88-0. Pack Sizes: 1 g. Product ID: B2693-463292. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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