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| Product | Description | |
|---|---|---|
| 2-Amino-2-(5-(5-(3-chloro-4-propoxyphenyl)-1,2,4-oxadiazol-3-yl)benzofuran-2-yl)propane-1,3-diol | AKP-11 is a novel agonist of sphingosine-1-phosphate receptor (S1PR) subtype 1 with the potential to treat multiple sclerosis (MS). Group: Pharmaceutical. Alternative Names: SCHEMBL177513; ACN-051239; AKP-11; ACN 051239; AKP 11; ACN051239; AKP11. CAS No. 1220973-37-4. Pack Sizes: 10 mg. Product ID: B0084-008121. Molecular formula: C22H22ClN3O5. Mole weight: 443.884. Custom synthesis is available. Send your inquiries for more information. |  London |
| 2-Amino-2',5-dichlorobenzophenone | 2-Amino-2',5-dichlorobenzophenone is a key intermediate in the synthesis of pharmaceuticals and research chemicals. It is used in the production of anticancer drugs and antitumor agents due to its potential to inhibit cancer cell growth. Additionally, it finds application in the research of various diseases related to cell proliferation and apoptosis. Group: Pharmaceutical. Alternative Names: Methanone, (2-amino-5-chlorophenyl)(2-chlorophenyl)-; Benzophenone, 2-amino-2',5-dichloro-; 2,5'-Dichloro-2'-aminobenzophenone; 2-Amino-5-chloro-2'-chlorobenzophenone; 2',5-Dichloro-2-aminobenzophenone; NSC 611905. CAS No. 2958-36-3. Pack Sizes: 1mg;1g;10g. Product ID: NP2988. Molecular formula: C13H9Cl2NO. Mole weight: 266.12. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-amino-3-chloropropan-1-ol hydrochloride | An impurity of Linezolid, an antibiotic against Gram-positive bacteria. Group: Pharmaceutical. Alternative Names: 2-Amino-3-chloropropan-1-ol hydrochloride; 54798-73-1; B0073-284949. CAS No. 54798-73-1. Pack Sizes: 100 mg. Product ID: B0073-284949. Molecular formula: C3H9Cl2NO. Mole weight: 146.02. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Amino-4-chlorobenzoic acid | 2-Amino-4-chlorobenzoic acid Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 89-77-0. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply. |  UK / EU / USA / Japan |
| 2-Amino-5-chloro-4-picoline (2-Amino-5-chloro-4-methylpyridine) | 5g Pack Size. Group: Building Blocks, Organics, Pyridines. Formula: C6H7ClN2. CAS No. 36936-27-3. Prepack ID : 61650840-5g. Molecular Weight : 142.59. |  |
| 2-Amino-5-chlorobenzophenone | 2-Amino-5-chlorobenzophenone. Group: Pharmaceutical. Alternative Names: 2-Benzoyl-4-chloroaniline; 5-Chloro-2-aminobenzophenone; NSC 84157; (2-Amino-5-chlorophenyl)phenylmethanone; Benzophenone, 2-amino-5-chloro-; 2-Amino-5-chlorbenzophenone; 2-Amino-5-chlorobenzylphenone. CAS No. 719-59-5. Pack Sizes: 1mg;1g;10g. Product ID: NP2960. Molecular formula: C13H10ClNO. Mole weight: 231.68. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Amino-6-chloro-3-nitropyridine | 2-Amino-6-chloro-3-nitropyridine Uses: Pharmaceutical R&D. Group: Chemicals & Intermediates. CAS No. 27048-04-0. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals (Formerly Melrob-Eurolabs). | UK / EU / USA / Japan |
| 2-Amino-6-chloro-3-nitropyridine | 5g Pack Size. Group: Building Blocks, Organics, Pyridines. Formula: C5H4ClN3O2. CAS No. 27048-04-0. Prepack ID : 30233633-5g. Molecular Weight : 173.56. | |
| 2-amino-6-chlorobenzoic acid | 2-amino-6-chlorobenzoic acid. CAS No. 2148-56-3. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| 2-Amino-6-chloropurine | 2-Amino-6-chloropurine (CAS# 10310-21-1) is a useful research chemical. Group: Pharmaceutical. Alternative Names: Famciclovir Related Compound F; 6-Chloroguanine; 6-Chloro-2-aminopurine; 6-Chloro-9H-purin-2-amine. CAS No. 10310-21-1. Pack Sizes: 1mg;1g;10g. Product ID: NP2957. Molecular formula: C5H4ClN5. Mole weight: 169.57. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Amino-6-chloropurine (6-Chloroguanine) | 100g Pack Size. Group: Building Blocks, Organics. Formula: C5H4ClN5. CAS No. 10310-21-1. Prepack ID : 10909764-100g. Molecular Weight : 169.57. | |
| 2-Amino-6-chloropurine (6-Chloroguanine) | 25g Pack Size. Group: Building Blocks, Organics. Formula: C5H4ClN5. CAS No. 10310-21-1. Prepack ID : 10909764-25g. Molecular Weight : 169.57. | |
| 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside | 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a remarkable biomedical entity, diligently confronting the pernicious wrath of herpes simplex virus and varicella-zoster virus, rendering them futile through the inhibition of viral DNA synthesis and replication. Group: Pharmaceutical. Alternative Names: 6-Chloro-2'-O-methylguanosine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-Amino-6-chloro-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(2-O-methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2'-O-Methyl-2-amino-6-chloropurine riboside. CAS No. 194034-59-8. Pack Sizes: 25 mg. Product ID: B2706-047011. Molecular formula: C11H14ClN5O4. Mole weight: 315.71. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide | 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide, is a precursor in the synthesis of Dasatinib, a protein tyrosine kinase inhibitor, and also for 2-Amino-thiazole-5-carboxylic Acid Phenylamide Derivatives, used as potent and selective anti-tumor drugs. Group: Pharmaceutical. Alternative Names: 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide. CAS No. 302964-24-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3528. Molecular formula: C11H10ClN3OS. Mole weight: 267.73. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile | One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: N-Methyl-N-(3R,4R)-1-cyanoacetyl-4-methylpiperidin-3-yl-2-chloro-7-deazapurine-6-amine; Tofacitinib Impurity 21. CAS No. 1616761-00-2. Pack Sizes: 25 mg. Product ID: B1370-379650. Molecular formula: C16H19ClN6O. Mole weight: 346.81. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Amino-2-chlorobenzonitrile | 4-Amino-2-chlorobenzonitrile Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 20925-27-3. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals. | UK / EU / USA / Japan |
| 5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde | Lapatinib intermediate. Group: Pharmaceutical. Alternative Names: 5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde. CAS No. 231278-84-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3184. Molecular formula: C26H17ClFN3O3. Mole weight: 473.88. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Amino-4-Chloro-o-Cresol HCl | 5-Amino-4-Chloro-o-Cresol HCl. Group: Pharmaceutical. Alternative Names: 5-amino-4-chloro-2-methylphenol hydrochloride. CAS No. 110102-85-7. Pack Sizes: 10 mg. Product ID: B0001-007050. Molecular formula: C7H9Cl2NO. Mole weight: 194.055. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Amino-4-chloro-1H-pyrazolo[3,4-d]pyrimidine | 6-Amino-4-chloro-1H-pyrazolo[3,4-d]pyrimidine. Group: Pharmaceutical. CAS No. 100644-65-3. Pack Sizes: 10 g. Product ID: BB000280. Molecular formula: C5H4ClN5. Mole weight: 169.57. Custom synthesis is available. Send your inquiries for more information. | London |
| N1-((1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Group: Pharmaceutical. Alternative Names: Ethanediamide, N-[(1S,2R,4S)-2-amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N'-(5-chloro-2-pyridinyl); Edoxaban Impurity I. CAS No. 480452-37-7. Pack Sizes: 100 mg. Product ID: B1370-377825. Molecular formula: C16H22ClN5O3. Mole weight: 367.83. Custom synthesis is available. Send your inquiries for more information. | London |
| N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide | N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, a potent kinase inhibitor, is prescribed for the management of diverse malignancies such as lung carcinoma and melanoma. Its mechanism of action encompasses the suppression of pivotal pathways implicated in the proliferation and advancement of neoplastic tissues. Group: Pharmaceutical. Alternative Names: 302964-08-5; N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide2-(6-chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamideN-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide. CAS No. 302964-08-5. Pack Sizes: 1mg;1g;10g. Product ID: 302964-08-5. Molecular formula: C16H13Cl2N5OS. Mole weight: 394.28. Custom synthesis is available. Send your inquiries for more information. | London |
| N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide | N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide is an impurity of Afatinib, which is a tyrosine kinase inhibitor used to treat non-small cell lung carcinoma (NSCLC). Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-; (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. CAS No. 439081-18-2. Pack Sizes: 500 mg. Product ID: B0084-092426. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Custom synthesis is available. Send your inquiries for more information. | London |
| N'-(5-Chloropyridin-2-yl)-N-[(1R,2R,4R)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide | An impurity of Edoxaban, a direct factor Xa inhibitor used as an anticoagulant. Group: Pharmaceutical. Alternative Names: Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-; N1-(5-Chloro-2-pyridinyl)-N2-[(1R,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide; N-(5-Chloropyridin-2-yl)-N'-[(1R,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide; N1-(5-Chloropyridin-2-yl)-N2-((1R,2R,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide; Edoxaban (1R,2R,4R) Isomer; Edoxaban (RRR)-Isomer; Edoxaban Impurity 25. CAS No. 1255529-24-8. Pack Sizes: 10 mg. Product ID: B2694-480568. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic acid hydrochloride | An impurity of Rivaroxaban, a factor Xa (FXa) inhibitor used for the prevention and treatment of thromboembolic disorders. Group: Pharmaceutical. Alternative Names: 2-[2-[[4-[(5S)?-5-[[[(5-Chloro-2-thienyl)?carbonyl]?amino]?methyl]?-2-oxo-3-oxazolidinyl]?phenyl]?amino]?ethoxy]?-acetic Acid Hydrochloride. CAS No. 931117-61-2. Pack Sizes: 10 mg. Product ID: B0145-008069. Molecular formula: C19H21Cl2N3O6S. Mole weight: 490.36. Custom synthesis is available. Send your inquiries for more information. | London |
| (1R,2S,5S)-2-Amino Edoxaban | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Group: Pharmaceutical. Alternative Names: Des((2-((5-chloro-2-pyridyl)amino)-2-oxo-acetyl))edoxaban; Edoxaban-M2. CAS No. 480450-71-3. Pack Sizes: 10 mg. Product ID: B1370-377831. Molecular formula: C17H27N5O2S. Mole weight: 365.5. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Chloro-2'-deoxyadenosine | 2'-Chloro-2'-deoxyadenosine, an essential nucleoside analog in the biomedical field, exhibits profound therapeutic potential for the treatment of diverse ailments, encompassing specific leukemias and lymphomas. By impairing DNA synthesis and instigating apoptosis in malignant cells, this medication emerges as an indispensable asset in combating these pernicious diseases, heralding optimism for the enhancement of patient prognoses. Group: Pharmaceutical. Alternative Names: 2'-chlorodeoxyadenosine; 2'-Deoxy-2'-chloroadenosine; (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-chloro-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 2627-62-5. Pack Sizes: 10 mg. Product ID: B1370-339143. Molecular formula: C10H12ClN5O3. Mole weight: 285.69. Custom synthesis is available. Send your inquiries for more information. | London |
| (2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | (2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide is a linker widely used in antibody-drug conjugates (ADCs). Group: Pharmaceutical. Alternative Names: (2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide. CAS No. 1797406-69-9. Pack Sizes: 10 mg. Product ID: BADC-01565. Molecular formula: C49H60ClN9O8S2. Mole weight: 1002.64. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Chloro-N-((3-chloro-5-fluorophenyl)carbamothioyl)benzamide | 3-Chloro-N-((3-chloro-5-fluorophenyl)carbamothioyl)benzamide is a novel chemical entity that is widely employed in scientific investigations aimed at uncovering the therapeutic potential of diverse human diseases. Recent evidence suggests that this compound may offer a promising mode of action in the treatment of select cancer types. Although ongoing research continues to elucidate its safety and effectiveness, the preliminary findings hold considerable promise for this molecule as a potentially life-saving drug candidate. Group: Pharmaceutical. Alternative Names: 3-Chloro-N-[[(3-chloro-5-fluorophenyl)amino]thioxomethyl]benzamide; Benzamide, 3-chloro-N-[[(3-chloro-5-fluorophenyl)amino]thioxomethyl]-. CAS No. 1796641-12-7. Pack Sizes: 50 mg. Product ID: B0001-284777. Molecular formula: C14H9Cl2FN2OS. Mole weight: 343.2. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride | An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Group: Pharmaceutical. Alternative Names: Des(5-Chloro-2-carboxythienyl) Rivaroxaban Hydrochloride; 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride; Rivaroxaban Impurity 27; (S)-4-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride. CAS No. 898543-06-1. Pack Sizes: 1mg;1g;10g. Product ID: NP3319. Molecular formula: C14H18ClN3O4. Mole weight: 327.76. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-ACMA hydrochloride | 7-ACMA is a synthetic compound belonging to the cephem class of antibiotics, which are structurally related to cephalosporins. Group: Pharmaceutical. Alternative Names: 7-Amino-3-chloromethyl-3-cephem-4-carboxylic acid diphenylmethyl ester hydrochloride; (6R,7R)-Benzhydryl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride. CAS No. 79349-53-4. Pack Sizes: 2 g. Product ID: B1370-072946. Molecular formula: C21H20Cl2N2O3S. Mole weight: 451.37. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Epi Clindamycin | 7-Epi Clindamycin, a highly efficacious antibiotic, exhibits remarkable efficacy against a wide range of bacterial infections. By discerningly impeding protein synthesis within bacterial organisms, it disrupts their growth and obstructs their survival, effectively eliminating the pernicious microorganisms. Distinctively versatile, this compound demonstrates its unwavering effectiveness against both Gram-positive and Gram-negative bacteria. Consequently, this invaluable asset plays an integral role in the biomedical field, diligently combatting infectious ailments with exceptional efficacy. Group: Pharmaceutical. Alternative Names: D-erythro-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, trans-α-; D-erythro-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, (2S-trans)-; Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; 7-Epiclindamycin; Antibiotic U 21251F. CAS No. 16684-06-3. Pack Sizes: 5 mg. Product ID: B1370-159244. Molecular formula: C18H33ClN2O5S. Mole weight: 424.98. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Epiclindamycin 2-Phosphate | 7-Epiclindamycin 2-Phosphate is an impurity of Clindamycin, an antibiotic medication used for the treatment of bacterial infections. Group: Pharmaceutical. Alternative Names: 7-Epiclindamycin phosphate; Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside 2-(Dihydrogen Phosphate); Clindamycin Phosphate EP Impurity L. CAS No. 620181-05-7. Pack Sizes: 1 mg. Product ID: B1370-119595. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96. Custom synthesis is available. Send your inquiries for more information. | London |
| A 33 | A 33 is a potent and selective PDE4B inhibitor (IC50 = 15 nM) that exhibits >100-fold selectivity for PDE4B over 4D. Group: Pharmaceutical. Alternative Names: 2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid. CAS No. 915082-52-9. Pack Sizes: 1mg;1g;10g. Product ID: 915082-52-9. Molecular formula: C19H18ClN3O2S. Mole weight: 387.88. Custom synthesis is available. Send your inquiries for more information. | London |
| A 357300 hydrochloride | A 357300 hydrochloride is a potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2). In murine models, it significantly inhibits CHP-134-derived neuroblastoma s.c. xenograft growth rate with a treatment-to-control (T/C) ratio at day 24 of 0.19 (P < 0.001) without toxicity. Uses: Novel treatment of neuroblastoma. Group: Pharmaceutical. Alternative Names: A-357300; A 357300; A357300; N'-(3-amino-2-hydroxy-5-(isopropylthio)pentanoyl)-3-chlorobenzohydrazide hydrochloride. CAS No. 369358-07-6. Pack Sizes: 1mg;1g;10g. Product ID: 369358-07-6. Molecular formula: C15H22ClN3O3S.HCl. Mole weight: 396.33. Custom synthesis is available. Send your inquiries for more information. | London |
| A-3 HYDROCHLORIDE | A-3 HYDROCHLORIDE. Group: Pharmaceutical. Alternative Names: A-3 HYDROCHLORIDE; A-3; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE; N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONA. CAS No. 78957-85-4. Pack Sizes: 1mg;1g;10g. Product ID: 78957-85-4. Molecular formula: C12H14Cl2N2O2S. Mole weight: 321.22. Custom synthesis is available. Send your inquiries for more information. | London |
| A-7 hydrochloride | A-7 hydrochloride is a cell-permeable antagonist of calmodulin that inhibits calmodulin-activated PDE activity with an IC50 of 3 μM. Calmodulin is a calcium-dependent protein expressed in all eukaryotic cells, modulating the interaction of calcium with target proteins. Group: Pharmaceutical. Alternative Names: A-7 monohydrochloride; A 7 hydrochloride; A7 hydrochloride; N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide hydrochloride; N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide monoydrochloride. CAS No. 79127-24-5. Pack Sizes: 1mg;1g;10g. Product ID: 79127-24-5. Molecular formula: C20H29ClN2O2S.HCl. Mole weight: 433.44. Custom synthesis is available. Send your inquiries for more information. | London |
| AAT-008 | AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4; IC50 = 16.3 nM in a human EP4 functional assay). Group: Pharmaceutical. Alternative Names: 4-[(1S)-1-[[5-chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acid. CAS No. 847727-81-5. Pack Sizes: 1mg;1g;10g. Product ID: 847727-81-5. Molecular formula: C21H16ClFN2O4. Mole weight: 414.8. Custom synthesis is available. Send your inquiries for more information. | London |
| Abacavir Impurity 1 | A metabolite of Abacavir in human urine and cerebrospinal fluid. Group: Pharmaceutical. Alternative Names: 2-Cyclopentene-1-methanol, 4-(2-amino-6-chloro-7H-purin-7-yl)?-, (1S-cis)?- (9CI). CAS No. 178327-20-3. Pack Sizes: 1mg;1g;10g. Product ID: 178327-20-3. Molecular formula: C11H14ClN5O. Mole weight: 267.72. Custom synthesis is available. Send your inquiries for more information. | London |
| Abacavir Impurity 2 | A metabolite of Abacavir in human urine and cerebrospinal fluid. Group: Pharmaceutical. Alternative Names: (1S,4R)-4-<(2',5'-diamino-6'-chloropyrimidin-4'-yl)amino>cyclopent-2-enylmethanol. CAS No. 122624-77-5. Pack Sizes: 1mg;1g;10g. Product ID: 122624-77-5. Molecular formula: C10H14ClN5O. Mole weight: 255.71. Custom synthesis is available. Send your inquiries for more information. | London |
| ABBV-167 | ABBV-167 is a phosphate prodrug of venetoclax, a Bcl-2 inhibitor. Group: Pharmaceutical. Alternative Names: Benzamide, 4-(4-((2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-2-((7-((phosphonooxy)methyl)-7H-pyrrolo(2,3-b)pyridin-5-yl)oxy)-; (5-{5-(4-{[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-2-[({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)carbamoyl]phenoxy}-7H-pyrrolo[2,3-b]pyridin-7-yl)methyl dihydrogen phosphate. CAS No. 1351456-78-4. Pack Sizes: 1mg;1g;10g. Product ID: 1351456-78-4. Molecular formula: C46H53ClN7O11PS. Mole weight: 978.45. Custom synthesis is available. Send your inquiries for more information. | London |
| ABC294640 | ABC294640 is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. Group: Pharmaceutical. Alternative Names: ABC-294640; ABC294640; ABC 294640; Opaganib; 3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide. CAS No. 915385-81-8. Pack Sizes: 1mg;1g;10g. Product ID: 915385-81-8. Molecular formula: C23H25ClN2O. Mole weight: 380.9104. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT 29666 | ABT 29666 is a therapeutic agent. Uses: A therapeutic agent. Group: Pharmaceutical. Alternative Names: ABT 29666; ABT29666; ABT-29666; Piperidine, 1-(3-((4-((p-chlorophenyl)azo)-5,6,7,8-tetrahydro-1-naphthyl)amino)propyl)-. CAS No. 3365-99-9. Pack Sizes: 1mg;1g;10g. Product ID: 3365-99-9. Molecular formula: C24H31ClN4. Mole weight: 410.22. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT-737 | ABT-737 is a potent, cell-permeable mimetic of BH3 domains that avidly binds Bcl-2, Bcl-xL, and Bcl-W (Ki < 1 nM for all three proteins). It blocks the interaction of these proteins with pro-death proteins, leading to apoptosis. Group: Pharmaceutical. Alternative Names: ABT 737; ABT737; (R)-4-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-(dimethylamino)-1-(phenylthio)butan-2-yl)amino)-3-nitrophenyl)sulfonyl)benzamide. CAS No. 852808-04-9. Pack Sizes: 100 mg. Product ID: B1370-139061. Molecular formula: C42H45ClN6O5S2. Mole weight: 813.43. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib | Afatinib irreversibly inhibits EGFR/HER2 including EGFR, EGFR(L858R), EGFR(L858R/T790M) and HER2. It is 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992; Gilotrif; Giotrif; Tovok; (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. CAS No. 850140-72-6. Pack Sizes: 500 mg. Product ID: B0084-258486. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib-[d6] | Afatinib-[d6] is the labelled analogue of Afatinib. Afatinib is a medication approved for the treatment of metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It acts via inhibiting EGFR and HER2. Group: Pharmaceutical. Alternative Names: Afatinib-d6; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6; Tovok-d6; Tomtovok-d6. CAS No. 1313874-96-2. Pack Sizes: 5 mg. Product ID: BLP-011554. Molecular formula: C24H19D6ClFN5O3. Mole weight: 491.98. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity C | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)?amino]?-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-6-quinazolinyl]?-4-(dimethylamino)?-, (2E)?-. CAS No. 945553-91-3. Pack Sizes: 10 mg. Product ID: B2694-466206. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity D | An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. Alternative Names: (2Z)-Afatinib; Z-Afatinib; (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. CAS No. 1680184-59-1. Pack Sizes: 5 mg. Product ID: B2694-466207. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity I | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. Alternative Names: Bromo-Afatinib; (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. CAS No. 1637254-93-3. Pack Sizes: 2.5 mg. Product ID: B1370-377782. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.78. Custom synthesis is available. Send your inquiries for more information. | London |
| Afoxolaner | Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies. It is administered orally in meat-flavoured tablets, and poisons fleas once they start feeding. It is used either alone or as a combination treatment with milbemycin oxime. Group: Pharmaceutical. Alternative Names: 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide. CAS No. 1093861-60-9. Pack Sizes: 100 mg. Product ID: B2692-475054. Molecular formula: C26H17ClF9N3O3. Mole weight: 625.87. Custom synthesis is available. Send your inquiries for more information. | London |
| Alisertib | MLN8237 is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. Group: Pharmaceutical. Alternative Names: MLN8237; MLN-8237; MLN 8237; alisertib. Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-. CAS No. 1028486-01-2. Pack Sizes: 100 mg. Product ID: B2693-336876. Molecular formula: C27H20ClFN4O4. Mole weight: 518.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Aminochlorthenoxazin | An antipyretic and non-narcotic analgesic agent. Group: Pharmaceutical. Alternative Names: 6-amino-2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one; aminochlorthenoxazine; aminochlorthenoxazine monohydrochloride. CAS No. 3567-76-8. Pack Sizes: 1mg;1g;10g. Product ID: 3567-76-8. Molecular formula: C10H11ClN2O2. Mole weight: 226.66. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine | Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Uses: Antihypertensive agents; calcium channel blockers; vasodilator agents. Group: Pharmaceutical. Alternative Names: Amlopres; Intervask; Pelmec; UK-48340; 3-ethyl 5-methyl ester 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid. CAS No. 88150-42-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3417. Molecular formula: C20H25ClN2O5. Mole weight: 408.87. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine besylate | Amlodipine Besylate is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Uses: Antihypertensive agents. Group: Pharmaceutical. Alternative Names: Amlodipine benzenesulfonate; 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfonate. CAS No. 111470-99-6. Pack Sizes: 1mg;1g;10g. Product ID: NP2627. Molecular formula: C20H25ClN2O5.C6H6O3S. Mole weight: 567.05. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine EP impurity B | Amlodipine EP impurity B is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Group: Pharmaceutical. Alternative Names: N-[2-[(Methylamino)carbonyl]benzoyl] Amlodipine; 3-Ethyl 5-methyl (4RS)-4-(2-chlorophenyl)-6-methyl-2-[[2-[[2-(methylcarbamoyl)benzoyl]amino]ethoxy]methyl]-1,4-dihydropyridine-3,5-dicarboxylate. CAS No. 721958-72-1. Pack Sizes: 250 mg. Product ID: B1370-466519. Molecular formula: C29H32ClN3O7. Mole weight: 570.03. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine EP Impurity D | Amlodipine EP Impurity D is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Group: Pharmaceutical. Alternative Names: 3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate; Dehydro Amlodipine. CAS No. 113994-41-5. Pack Sizes: 25 mg. Product ID: B1370-466516. Molecular formula: C20H23ClN2O5. Mole weight: 406.86. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine EP Impurity D Oxalate | Amlodipine EP Impurity D Oxalate is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Group: Pharmaceutical. Alternative Names: 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Oxalate; Dehydro Amlodipine Oxalate; Amlodipine USP Related Compound A; 3-Ethyl 5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate oxalate salt. CAS No. 1216406-90-4. Pack Sizes: 25 mg. Product ID: B1370-118639. Molecular formula: C20H23ClN2O5.C2H2O4. Mole weight: 496.89. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine EP Impurity E | Amlodipine EP Impurity E is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Uses: Amlodipine besilate (a633500) impurity. Group: Pharmaceutical. Alternative Names: Amlodipine USP Related Compound E; Amlodipine Diethyl Ester; 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylic acid diethyl ester; 3-Ethyl 5-Ethyl 4-(2-Chlorophenyl)-6-methyl-2-[[2-[(2-aminoethoxy)methyl]-1,4-dihydropyridine-3,5-dicarboxylate. CAS No. 140171-65-9. Pack Sizes: 50 mg. Product ID: B0055-258755. Molecular formula: C21H27ClN2O5. Mole weight: 422.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine EP Impurity F | Amlodipine EP Impurity F is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Uses: Amlodipine besilate (a633500) impurity. Group: Pharmaceutical. Alternative Names: Amlodipine Dimethyl Ester; 3-Methyl 5-Methyl 4-(2-Chlorophenyl)-6-methyl-2-[[2-[(2-aminoethoxy)methyl]-1,4-dihydropyridine-3,5-dicarboxylate. CAS No. 140171-66-0. Pack Sizes: 50 mg. Product ID: B0055-258756. Molecular formula: C19H23ClN2O5. Mole weight: 394.85. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine Mannitol Adduct | Amlodipine Mannitol Adduct is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Group: Pharmaceutical. Alternative Names: Amlodipine Mannitol; 3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-((2-(((2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)methyl)-1,4-dihydropyridine-3,5-dicarboxylate. Pack Sizes: 10 mg. Product ID: B1370-352613. Molecular formula: C26H37ClN2O10. Mole weight: 573.03. Custom synthesis is available. Send your inquiries for more information. | London |
| Amlodipine Related Compound A | Amlodipine Related Compound A is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Group: Pharmaceutical. Alternative Names: Dehydro amlodipine fumarate; 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic acid, 3-ethyl 5-methyl ester, 2-butenedioate; Amlodipine EP Impurity D Fumarate; 3-Ethyl 5-methyl [2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylate] fumarate. CAS No. 2138811-33-1. Pack Sizes: 10 mg. Product ID: B0055-003994. Molecular formula: C20H23ClN2O5.C4H4O4. Mole weight: 522.93. Custom synthesis is available. Send your inquiries for more information. | London |
| ARV-771 | ARV-771 is a potent BET bromodomain PROTAC® Degrader based on von Hippel-Lindau (VHL) E3 ligase, consisting of a BRD4-binding moiety bound to a VHL ligand via a linker. Group: Pharmaceutical. Alternative Names: ARV 771; ARV771; (2S,4R)-1-((S)-2-(tert-butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,14-dioxo-6,10-dioxa-3,13-diazapentadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide; L-Prolinamide, N-[2-[3-[2-[[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]amino]ethoxy]propoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-; N-({3-[2-({[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl}amino)ethoxy]propoxy}acetyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-{(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl}-L-prolinamide. CAS No. 1949837-12-0. Pack Sizes: 5 mg. Product ID: B2693-007297. Molecular formula: C49H60ClN9O7S2. Mole weight: 986.64. Custom synthesis is available. Send your inquiries for more information. | London |
| ARV-825 | ARV-825 is a BRD4 inhibitor based on PROTAC technology. ARV-825 recruits BRD4 to E3 ubiquitin ligase cereblon, resulting in the degradation of BRD4. In post-myeloproliferative neoplasm secondary (s) AML cell lines, treatment with ARV-825 induces apoptosis and inhibits cell proliferation. Group: Pharmaceutical. Alternative Names: 2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)ethoxy)phenyl)acetamide. CAS No. 1818885-28-7. Pack Sizes: 100 mg. Product ID: B1370-474664. Molecular formula: C46H47ClN8O9S. Mole weight: 923.44. Custom synthesis is available. Send your inquiries for more information. | London |
| AT13148 | AT13148 is an orally available multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity. It can block phosphorylation of AKT, p70S6K, PKA, ROCK and SGK substrates, and induce apoptosis in cancer cells. Group: Pharmaceutical. Alternative Names: AT-13148; (1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol. CAS No. 1056901-62-2. Pack Sizes: 50 mg. Product ID: B0084-462670. Molecular formula: C17H16ClN3O. Mole weight: 313.78. Custom synthesis is available. Send your inquiries for more information. | London |
| AU-224 | AU-224, a benzamide derivative, exhibited potent gastro- and colon-prokinetic activities by oral administration without significant side effects. Group: Pharmaceutical. Alternative Names: 1-Piperidineacetic acid, 4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-, butyl ester; butyl 2-[4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]piperidin-1-yl]acetate; AU-224; butyl 4-((4-amino-5-chloro-2-methoxybenzoyl)amino)-1-piperidineacetate; AU 224;AU224. CAS No. 287399-47-7. Pack Sizes: 1mg;1g;10g. Product ID: 287399-47-7. Molecular formula: C19H28ClN3O4. Mole weight: 397.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Avagacestat | BMS-708163 is a potent and orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP (IC50 = 0.30 nM) to Aβ40 than signaling through Notch (IC50s = 58 nM). Uses: Gamma secretase inhibitors and modulators. Group: Pharmaceutical. Alternative Names: Avagacestat; BMS 708163; (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide. CAS No. 1146699-66-2. Pack Sizes: 50 mg. Product ID: B0084-286394. Molecular formula: C20H17ClF4N4O4S. Mole weight: 520.89. Custom synthesis is available. Send your inquiries for more information. | London |
| Batefenterol | Batefenterol is a Beta 2 adrenergic receptor agonist and also a Muscarinic receptor antagonist. It shows high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM). Batefenterol is a hβ2-adrenoceptor agonist with EC50 value of 0.29 nM for stimulation of cAMP levels. This is 440- and 320-fold functional selectivity over hβ1- and hβ3-adrenoceptors. In Jul 2016, GlaxoSmithKline completed a phase II trial for Chronic obstructive pulmonary disease in USA, Germany and South Africa. Uses: Chronic obstructive pulmonary disease. Group: Pharmaceutical. Alternative Names: GSK-961081; TD-5959; GSK 961081; TD 5959; GSK961081; TD5959; (R)-1-(3-((2-chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate. CAS No. 743461-65-6. Pack Sizes: 25 mg. Product ID: B0084-476591. Molecular formula: C40H42ClN5O7. Mole weight: 740.25. Custom synthesis is available. Send your inquiries for more information. | London |
| Belnacasan | Belnacasan is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan inhibits interlukin-1β biosynthesis. Group: Pharmaceutical. Alternative Names: VX 765, VX765, VX-765, Belnacasan; (2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide. CAS No. 273404-37-8. Pack Sizes: 50 mg. Product ID: B0084-307700. Molecular formula: C24H33ClN4O6. Mole weight: 509. Custom synthesis is available. Send your inquiries for more information. | London |
| Bendamustine Chloro Dimer Impurity | Bendamustine Chloro Dimer Impurity is an impurity of Bendamustine, a chemotherapy medication indicated for the treatment of chronic lymphocytic leukemia, multiple myeloma, and non-Hodgkin's lymphoma. Group: Pharmaceutical. Alternative Names: Bendamustine Dimer Impurity; 5-[bis(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 2-[[2-(3-Carboxypropyl)-1-methyl-1H-benzimidazol-5-yl](2-chloroethyl)amino]ethyl Ester. CAS No. 1228551-91-4. Pack Sizes: 10 mg. Product ID: B2694-467289. Molecular formula: C32H41Cl3N6O4. Mole weight: 680.08. Custom synthesis is available. Send your inquiries for more information. | London |
| Betrixaban | A direct factor Xa inhibitor used as an oral anticoagulant drug. It has been prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE. Uses: Factor xa inhibitors. Group: Pharmaceutical. Alternative Names: PRT054021; PRT 054021; PRT-054021; MK-4448; MK 4448; MK4448; PRT-021; PRT 021; PRT021; MLN-1021; MLN 1021; MLN1021; Bevyxxa; N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide. CAS No. 330942-05-7. Pack Sizes: 25 mg. Product ID: B0084-090322. Molecular formula: C23H22ClN5O3. Mole weight: 451.91. Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-536924 | BMS-536924 is a potent small molecule inhibitor of IGF-IR, which shows antitumor activity in multiple tumor models, including sarcoma. Group: Pharmaceutical. Alternative Names: BMS536924; BMS 536924; Insulin-like Growth Factor-1 Receptor Inhibitor; (S)-4-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one. CAS No. 468740-43-4. Pack Sizes: 50 mg. Product ID: B1370-142616. Molecular formula: C25H26ClN5O3. Mole weight: 479.96. Custom synthesis is available. Send your inquiries for more information. | London |
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