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| Product | Description | |
|---|---|---|
| BML-284 | BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Group: Pharmaceutical. Alternative Names: BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine. CAS No. 853220-52-7. Pack Sizes: 25 mg. Product ID: B0084-474867. Molecular formula: C19H18N4O3. Mole weight: 350.37. Custom synthesis is available. Send your inquiries for more information. |  London |
| Fmoc-S-benzyl-D-penicillamine | Fmoc-S-benzyl-D-penicillamine is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Group: Pharmaceutical. Alternative Names: Fmoc-D-Pen(Bzl)-OH; Fmoc-S-benzyl-β,β-dimethyl-D-Cys-OH; Fmoc-D-Pen(Bn)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(benzylthio)-3-methylbutanoic acid; 3-(Benzylsulfanyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-valine; N-α-(9-Fluorenylmethoxycarbonyl)-S-benzyl-D-penicillamine. CAS No. 139551-73-8. Pack Sizes: 1mg;1g;10g. Product ID: BAT-007489. Molecular formula: C27H27NO4S. Mole weight: 461.57. Custom synthesis is available. Send your inquiries for more information. | London |
| PKC-Theta Inhibitor | PKC-theta inhibitor is a selective PKC-theta inhibitor with IC50 of 12 nM. Group: Pharmaceutical. Alternative Names: CHEMBL248183; N4-((4-(Aminomethyl)Cyclohexyl)Methyl)-5-Nitro-N2-(2-(Trifluoromethoxy)Benzyl)Pyrimidine-2,4-Diamine; VC-8650; SCHEMBL3953579. CAS No. 736048-65-0. Pack Sizes: 5 mg. Product ID: B2693-373030. Molecular formula: C20H25F3N6O3. Mole weight: 454.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Safinamide Impurity 5 | An impurity of Safinamide, a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Group: Pharmaceutical. Alternative Names: (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanoic acid; (2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanoic acid. CAS No. 1160513-60-9. Pack Sizes: 25 mg. Product ID: B2694-479401. Molecular formula: C17H18FNO3. Mole weight: 303.34. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-NP-AMOZ-[d5] | 2-NP-AMOZ-[d5] is the labelled analogue of 2-NP-AMOZ, which is a derivative of AMOZ, a metabolite of Nitrofuran. Group: Pharmaceutical. Alternative Names: 5-Morpholin-4-ylmethyl-3-[(2-nitro-benzylidene)-amino]-oxazolidin-2-one-D5; 2-NP-AMOZ-D5; 5-(4-Morpholinylmethyl)-3-[[(2-nitrophenyl)methylene]amino]-2-oxazolidinone-d5. CAS No. 1173097-59-0. Pack Sizes: 5 mg. Product ID: BLP-012949. Molecular formula: C15H13D5N4O5. Mole weight: 339.36. Custom synthesis is available. Send your inquiries for more information. | London |
| (2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | (2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide is a linker widely used in antibody-drug conjugates (ADCs). Group: Pharmaceutical. Alternative Names: (2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide. CAS No. 1797406-69-9. Pack Sizes: 10 mg. Product ID: BADC-01565. Molecular formula: C49H60ClN9O8S2. Mole weight: 1002.64. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Benzyl Albuterol | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Group: Pharmaceutical. Alternative Names: α1-[[(1,1-Dimethylethyl)amino]methyl]-4-(phenylmethoxy)-1,3-benzenedimethanol; 1-(4-Benzyloxy-3-hydroxymethyl-phenyl)-2-(tert-butylamino)ethanol. CAS No. 56796-66-8. Pack Sizes: 200 mg. Product ID: B2694-126103. Molecular formula: C20H27NO3. Mole weight: 329.44. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-(Fmoc-amino)benzyl Alcohol | 4-(Fmoc-amino)benzyl Alcohol (CAS# 475160-83-9 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: (9H-Fluoren-9-yl)methyl (4-(hydroxymethyl)phenyl)carbamate; Fmoc-p-aminobenzyl alcohol. CAS No. 475160-83-9. Pack Sizes: 100 mg. Product ID: B1370-318318. Molecular formula: C22H19NO3. Mole weight: 345.4. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol | An impurity of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Group: Pharmaceutical. Alternative Names: (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol. CAS No. 142217-78-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3098. Molecular formula: C52H49N5O5. Mole weight: 824. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Amino-2,3,4,6-tetra-O-benzyl-5-deoxy-D-glucono-1,5-lactam | 5-Amino-2,3,4,6-tetra-O-benzyl-5-deoxy-D-glucono-1,5-lactam, a biochemical compound of wide repute, has garnered attention as a precursor for the synthesis of C-glycosyl tryptophan derivatives, and serves as a linchpin for the preparation of monosaccharides and heterocycles. With its conception rooted in chemical synthesis, this compound has exhibited potent pharmacological activity, signifying possible application in drug development aimed at remedying a range of ailments. Group: Pharmaceutical. Alternative Names: 2-Piperidinone, 3,4,5-tris(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, (3R,4S,5R,6R)-. CAS No. 77174-08-4. Pack Sizes: 100 mg. Product ID: B1999-006597. Molecular formula: C34H35NO5. Mole weight: 537.656. Custom synthesis is available. Send your inquiries for more information. | London |
| ACBI1 | ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. Group: Pharmaceutical. Alternative Names: ACBI 1; ACBI-1; (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide. CAS No. 2375564-55-7. Pack Sizes: 1mg;1g;10g. Product ID: 2375564-55-7. Molecular formula: C49H58FN9O7S. Mole weight: 936.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Aliskiren hemifumarate | Aliskiren is a direct renin inhibitor used for the treatment of essential hypertension. Group: Pharmaceutical. Alternative Names: (αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeno-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonaoyl-2-methyl-propyl)-amide hemifumarate. CAS No. 173334-58-2. Pack Sizes: 100 mg. Product ID: B0293-466286. Molecular formula: C30H53N3O6·1/2C4H4O4. Mole weight: 1219.6. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Ala(18)-Semaglutide | D-Ala(18)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: [D-Ala18]-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48R,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Pack Sizes: 5 mg. Product ID: B1370-449831. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Ala(19)-Semaglutide | D-Ala(19)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: D-Ala-19-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51R,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Pack Sizes: 5 mg. Product ID: B1370-449832. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Ala(24)-Semaglutide | D-Ala(24)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: D-Ala-24-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24R,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Pack Sizes: 5 mg. Product ID: B1370-449836. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| [D-Arg30]-Semaglutide | [D-Arg30]-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6R,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Pack Sizes: 5 mg. Product ID: B1370-449841. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Asp(9)-Semaglutide | D-Asp(9)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: (3S,9S,12S,15S,18S,21R,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Pack Sizes: 5 mg. Product ID: B1370-449824. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| Dermorphin | Dermorphin, a naturally occurring heptapeptide originally found in the skin of amphibians, is a μ-opioid receptor(MOR) agonist with analgesic and antinociceptive effects. Group: Pharmaceutical. Alternative Names: H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2; L-tyrosyl-D-alanyl-L-phenylalanyl-glycyl-L-tyrosyl-L-prolyl-L-serinamide; (S)-N-((S)-1-amino-3-hydroxy-1-oxopropan-2-yl)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-2-(4-hydroxybenzyl)-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)pyrrolidine-2-carboxamide. CAS No. 77614-16-5. Pack Sizes: 10 mg. Product ID: BAT-006192. Molecular formula: C40H50N8O10. Mole weight: 802.87. Custom synthesis is available. Send your inquiries for more information. | London |
| [D-Glu3]-Semaglutide | [D-Glu3]-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: (3R,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Pack Sizes: 5 mg. Product ID: B1370-449821. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Ser(11)-Semaglutide | D-Ser(11)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: D-[Ser]-11-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27R,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Pack Sizes: 5 mg. Product ID: B1370-087489. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Ser(12)-Semaglutide | D-Ser(12)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: D-Ser-12-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30R,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamo. Pack Sizes: 5 mg. Product ID: B1370-449827. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Val(10)-Semaglutide | D-Val(10)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: D-[Val]10-Semaglutide; D-[Val]-10-Semaglutide; (3S,9S,12S,15S,18S,21S,24R,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-Indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic Acid. Pack Sizes: 5 mg. Product ID: B1370-449825. Molecular formula: C187H291N45O59. Mole weight: 4113.64. Custom synthesis is available. Send your inquiries for more information. | London |
| Elagolix sodium | Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Uses: Endometriosis; uterine leiomyoma. Group: Pharmaceutical. Alternative Names: Sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate; NBI56418; NBI-56418; NBI 56418. CAS No. 832720-36-2. Pack Sizes: 25 mg. Product ID: B0084-354739. Molecular formula: C32H29F5N3NaO5. Mole weight: 653.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib EP Impurity D | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Group: Pharmaceutical. Alternative Names: Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride; 1-Methyl-1,4-bis[4-[(4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl)carbamoyl]benzyl]piperazin-1-ium chloride. CAS No. 1821122-73-9. Pack Sizes: 100 mg. Product ID: B2694-473167. Molecular formula: C53H51ClN12O2. Mole weight: 923.5. Custom synthesis is available. Send your inquiries for more information. | London |
| L-685,458 | L-685,458 is a potent and selective inhibitor of γ-secretase (IC50 = 17 nM) that shows 50-fold selectivity over a variety of aspartyl proteases. It also inhibits Aβ40 and Aβ42 peptides (in human neuroblastoma cells: IC50 = 48 and 67 nM respectively). Uses: Gamma secretase inhibitors and modulators. Group: Pharmaceutical. Alternative Names: L-685458; tert-butyl N-[(2S,3R,5R)-6-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate. CAS No. 292632-98-5. Pack Sizes: 25 mg. Product ID: B2693-286396. Molecular formula: C39H52N4O6. Mole weight: 672.85. Custom synthesis is available. Send your inquiries for more information. | London |
| Monodecarboxy piperacilloic acid | An impurity of Piperacillin, which is a broad-spectrum antibiotic used to treat serious, hospital-acquired infections in combination with the beta lactamase inhibitor tazobactam. Group: Pharmaceutical. Alternative Names: 4-Thiazolidinecarboxylic acid, 2-[[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]methyl]-5,5-dimethyl-, [2R-[2α(R*),4β]]-; α-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)benzylpenilloic acid; (2R,4S)-2-(((R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)methyl)-5,5-dimethylthiazolidine-4-carboxylic acid; Penilloic acids of piperacillin; Piperacillin EP Impurity C (2R-isomer). CAS No. 64817-23-8. Pack Sizes: 10 mg. Product ID: B2694-478852. Molecular formula: C22H29N5O6S. Mole weight: 491.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Obicetrapib | Obicetrapib is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors can increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may help reduce the risk of cardiovascular disease. Group: Pharmaceutical. Alternative Names: 1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl][5-(3-carboxypropoxy)-2-pyrimidinyl]amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-ethyl ester, (2R,4S)-; 1-Ethyl (2R,4S)-4-[[[3,5-bis(trifluoromethyl)phenyl]methyl][5-(3-carboxypropoxy)-2-pyrimidinyl]amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-1(2H)-quinolinecarboxylate; (2R,4S)-4-[[3,5-Bis(trifluoromethyl)benzyl][5-(3-carboxypropoxy)pyrimidin-2-yl]amino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester; AMG-899; AMG 899; AMG899; TA-8995; TA8995; TA 8995; DEZ-001; DEZ 001; DEZ001; Obicetrapib (free base). CAS No. 866399-87-3. Pack Sizes: 25 mg. Product ID: B1370-447410. Molecular formula: C32H31F9N4O5. Mole weight: 722.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Oritavancin diphosphate | Oritavancin, also known as LY333328, is a novel semisynthetic glycopeptide antibiotic. Oritavancin possesses potent and rapid bactericidal activity in vitro against a broad spectrum of both resistant and susceptible Gram-positive bacteria, including Staphylococcus aureus, MRSA, enterococci, and streptococci. Uses: Anti-bacterial agents. Group: Pharmaceutical. Alternative Names: (4R)-22-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-α-L-arabinohexopyranosyl)-N3-(p-(p-chlorophenyl)benzyl)vancomycin diphosphate; LY333328; LY-333328; LY 333328. CAS No. 192564-14-0. Pack Sizes: 50 mg. Product ID: BBF-04135. Molecular formula: C86H103Cl3N10O34P2. Mole weight: 1989.09. Custom synthesis is available. Send your inquiries for more information. | London |
| Piperacilloic Acid | An impurity of Piperacillin, which is a broad-spectrum antibiotic used to treat serious, hospital-acquired infections in combination with the beta lactamase inhibitor tazobactam. Group: Pharmaceutical. Alternative Names: Piperacillin penicilloic acid; 2-Thiazolidineacetic acid, 4-carboxy-α-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-5,5-dimethyl-, 2R-[2α[R*(R*)],4β]]-; Glycine, (2R)-N-[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]-2-phenylglycyl-2-[(2R,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]-, (2R)-; (2R,4S)-2-((R)-Carboxy((R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)methyl)-5,5-dimethylthiazolidine-4-carboxylic acid; α-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)benzylpenicilloic acid; Penicilloic acids of piperacillin. CAS No. 64817-22-7. Pack Sizes: 10 mg. Product ID: B2694-121534. Molecular formula: C23H29N5O8S. Mole weight: 535.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Protein degrader 1 hydrochloride | Protein degrader 1 hydrochloride is a building block used in the synthesis of PROTAC for the recruitment of the von Hippel-Lindau (VHL) protein. Group: Pharmaceutical. Alternative Names: (S,R,S)-AHPC hydrochloride; (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride. CAS No. 1448189-80-7. Pack Sizes: 25 mg. Product ID: B0084-007385. Molecular formula: C22H31ClN4O3S. Mole weight: 467.02. Custom synthesis is available. Send your inquiries for more information. | London |
| Rigosertib sodium | Rigosertib (ON-01910 sodium salt), a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity, is a non-ATP-competitive inhibitor of PLK1 (IC50=9 nM), inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. This agent may exhibit synergistic antitumor activity in combination with other chemotherapeutic agents. Plk1, named after the polo gene of Drosophila melanogaster, is a serine/threonine protein kinase involved in regulating mitotic spindle function in a non-ATP competitive manner. Group: Pharmaceutical. Alternative Names: Glycine, N-[2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-, monosodium salt (9CI); (E)-2,4,6-Trimethoxystyryl 3-[(carboxymethyl)amino]-4-methoxybenzyl sulfone sodium salt; Novonex; ON 01910 sodium; ON01910 sodium; ON-01910 sodium; ON 01910 sodium salt; Rigosertib sodium. CAS No. 1225497-78-8. Pack Sizes: 50 mg. Product ID: B0084-286621. Molecular formula: C21H24NNaO8S. Mole weight: 473.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Sufugolix | Sufugolix, also known as TAK-013, is a highly potent, non-peptide and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.1 nM. Sufugolix was under development to treat endometriosis and uterine leiomyoma and undergone testing in a phase II clinical study in both of these indications, but was subsequently discontinued. Group: Pharmaceutical. Alternative Names: 1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea; 5-(N-benzyl-N-methylaminomethyl)-1--(2,6-difluorobenzyl)-6-(4-(3-methoxyureido)phenyl)-3-phenylthieno(2,3-d)pyrimidine-2,4(1H,3H)-dione; Sufugolix; TAK-013; TAK013; TAK 013. CAS No. 308831-61-0. Pack Sizes: 100 mg. Product ID: B2693-106538. Molecular formula: C36H31F2N5O4S. Mole weight: 667.72. Custom synthesis is available. Send your inquiries for more information. | London |
| TAK-448 | TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Group: Pharmaceutical. Alternative Names: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. CAS No. 1234319-68-6. Pack Sizes: 25 mg. Product ID: BAT-010642. Molecular formula: C58H80N16O14. Mole weight: 1225.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Valsartan benzyl ester | An intermediate of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Group: Pharmaceutical. Alternative Names: Valsartan Impurity B; Benzyl (2S)-3-methyl-2-[pentanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoate; Valsartan Related Compound C; N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine phenylmethyl ester; USP Valsartan Related Compound C; Valsartan USP Related Compound C; (S)-Benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate; L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, phenylmethyl ester; Benzyl N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-pentanoyl-L-valinate; N-Valeryl-N-{[2'-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl}-L-valine benzyl ester; Valsartan EP Impurity B. CAS No. 137863-20-8. Pack Sizes: 25 mg. Product ID: B2694-394752. Molecular formula: C31H35N5O3. Mole weight: 525.66. Custom synthesis is available. Send your inquiries for more information. | London |
| Z-Phe-DL-Ala-FMK | Z-FA-FMK is an irreversible cysteine protease inhibitor, and it also inhibits caspases-2, -3, -6, and -7. Z-FA-FMK suppresses the degradation of fibrillar collagen by fibroblasts and osteoclasts, and reduces LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages. Uses: Cysteine proteinase inhibitors. Group: Pharmaceutical. Alternative Names: Z-Phe-DL-Ala-fluoromethylketone; Zfa-fmk; benzyloxycarbonyl-Phe-Ala-fluormethylketone; benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone; Carbamic acid, N-((1S)-2-((3-fluoro-1-methyl-2-oxopropyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester. CAS No. 197855-65-5. Pack Sizes: 50 mg. Product ID: B0084-209259. Molecular formula: C21H23FN2O4. Mole weight: 386.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Z-Val-Gly-Arg-pNA acetate salt | Z-Val-Gly-Arg-pNA is a colorimetric substrate for urokinase. Group: Pharmaceutical. Alternative Names: L-Argininamide, N-[(phenylmethoxy)carbonyl]-L-valylglycyl-N-(4-nitrophenyl)-, monoacetate; Carbobenzoxy-valyl-glycyl-arginine-p-nitroanilide acetate; Chromozym TRY acetate; Z-Val-Gly-Arg p-nitroanilide acetate salt; N-[(Phenylmethoxy)carbonyl]-L-valylglycyl-N-(4-nitrophenyl)-L-argininamide acetate salt; Cbz-Val-Gly-Arg-pNA acetate salt; Benzyl ((S)-1-((2-(((S)-5-guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)amino)-2-oxoethyl)amino)-3-methyl-1-oxobutan-2-yl)carbamate acetate salt. CAS No. 86170-43-6. Pack Sizes: 10 mg. Product ID: BAT-010823. Molecular formula: C29H40N8O9. Mole weight: 644.68. Custom synthesis is available. Send your inquiries for more information. | London |
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