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| Product | Description | |
|---|---|---|
| 2-Phenoxyaniline | 25g Pack Size. Group: Amines, Biochemicals, Building Blocks, Ligands. Formula: C12H11NO. CAS No. 2688-84-8. Prepack ID : 29529332-25g. Molecular Weight : 185.22. |  |
| 4-Amino-1-butanol | A reagent used in the synthesis of NSAIDs and cyclic amines. It is also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells. Group: Pharmaceutical. Alternative Names: H-Abu(4)-ol; NH2-(CH2)4-OH; δ-Amino-n-butyl alcohol; 4-aminobutan-1-ol; 4-Aminobutanol. CAS No. 13325-10-5. Pack Sizes: 500 g. Product ID: BAT-000662. Molecular formula: C4H11NO. Mole weight: 89.14. Custom synthesis is available. Send your inquiries for more information. |  London |
| Ethylenediamine | 500ml Pack Size. Group: Amines, Building Blocks, Ligands, Organics. Formula: C2H8N2. CAS No. 107-15-3. Prepack ID : 89966808-500ml. Molecular Weight : 60.1. | |
| Fluorescamine | 100mg Pack Size. Group: Amines, Ligands, Stains & Indicators. Formula: C17H10O4. CAS No. 38183-12-9. Prepack ID : 57916662-100mg. Molecular Weight : 278.26. | |
| HEDTA-Trisodium Salt 41% in H2O | 25g Pack Size. Group: Amines, Analytical Reagents, Biochemicals, Ligands. Formula: C10H15N2Na3O7. CAS No. 139-89-9. Prepack ID : 53149122-25g. Molecular Weight : 344.2. | |
| Iminodiacetic acid | 500g Pack Size. Group: Amines, Building Blocks, Ligands, Organics. Formula: HN(CH2CO2H)2. CAS No. 142-73-4. Prepack ID : 32314250-500g. Molecular Weight : 133.1. | |
| RO1138452 | RO1138452 is one of the most potent high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. It exhibits no affinity at other prostanoid receptors (EP1-4, FP and TP) in a radioligand binding assay. RO1138452 antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Group: Pharmaceutical. Alternative Names: RO-1138452; RO1138452; RO 1138452; CAY10441; CAY-10441; CAY 10441; N-(4-(4-Isopropoxybenzyl)phenyl)-4,5-dihydro-1H-imidazol-2-amine. CAS No. 221529-58-4. Pack Sizes: 50 mg. Product ID: B0084-205752. Molecular formula: C19H23N3O. Mole weight: 309.413. Custom synthesis is available. Send your inquiries for more information. | London |
| Triethylenetetramine | 500g Pack Size. Group: Amines, Building Blocks, Catalysts, Ligands, Organics. Formula: NH2CH2CH2 (NHCH2CH2)2NH2. CAS No. 112-24-3. Prepack ID : 89967212-500g. Molecular Weight : 146.23. | |
| 4-Di methyl aminoantipyrine | 100g Pack Size. Group: Analytical Reagents, Building Blocks, Ligands, Organics. Formula: C13H17N3O. CAS No. 58-15-1. Prepack ID : 27652384-100g. Molecular Weight : 231.29. | |
| ACBI1 | ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. Group: Pharmaceutical. Alternative Names: ACBI 1; ACBI-1; (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide. CAS No. 2375564-55-7. Pack Sizes: 1mg;1g;10g. Product ID: 2375564-55-7. Molecular formula: C49H58FN9O7S. Mole weight: 936.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Angiotensin A | Angiotensin A is a potent endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. It shows similar affinity for AT1 and AT2 receptors as angiotensin II with Ki values of 1.6 and 2.3 nM in vitro. It causes pressor and renal vasoconstrictor effects in rodents by the AT1 receptor. It is inhibited by Candesartan but not by AT2 receptor ligands in vivo. It also increases inositol phosphate accumulation with a similar potency to Ang II with EC50 value of 6.7 nM. Group: Pharmaceutical. Alternative Names: Ala-Angiotensin III; H-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; Ang A; Angiotensin II, 1-L-alanine-5-L-isoleucine-; L-alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine. CAS No. 51833-76-2. Pack Sizes: 10 mg. Product ID: BAT-015367. Molecular formula: C49H71N13O10. Mole weight: 1002.18. Custom synthesis is available. Send your inquiries for more information. | London |
| ARV-771 | ARV-771 is a potent BET bromodomain PROTAC® Degrader based on von Hippel-Lindau (VHL) E3 ligase, consisting of a BRD4-binding moiety bound to a VHL ligand via a linker. Group: Pharmaceutical. Alternative Names: ARV 771; ARV771; (2S,4R)-1-((S)-2-(tert-butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,14-dioxo-6,10-dioxa-3,13-diazapentadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide; L-Prolinamide, N-[2-[3-[2-[[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]amino]ethoxy]propoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-; N-({3-[2-({[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl}amino)ethoxy]propoxy}acetyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-{(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl}-L-prolinamide. CAS No. 1949837-12-0. Pack Sizes: 5 mg. Product ID: B2693-007297. Molecular formula: C49H60ClN9O7S2. Mole weight: 986.64. Custom synthesis is available. Send your inquiries for more information. | London |
| BAPTA (1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid) | 1g Pack Size. Group: Biochemicals, Ligands. Formula: C22H24N2O10. CAS No. 85233-19-8. Prepack ID : 20358510-1g. Molecular Weight : 476.43. | |
| β-Aspartylaspartic acid | An impurity of L-Ornithine L-aspartate salt which is used as a ligand in targeting SDF-1/CXCL12 with ligands that prevents activation of CXCR4 through structure-based drug design. Group: Pharmaceutical. Alternative Names: Ornithine aspartate-2; Ornithine aspartate impurity B; L-Ornithine L-Aspartate Impurity 2; beta-Asp-Asp; (2S)-2-[[(3S)-3-amino-3-carboxypropanoyl]amino]butanedioic acid; ((S)-3-amino-3-carboxypropanoyl)-L-aspartic acid. CAS No. 60079-22-3. Pack Sizes: 1mg;1g;10g. Product ID: BAT-009105. Molecular formula: C8H12N2O7. Mole weight: 248.19. Custom synthesis is available. Send your inquiries for more information. | London |
| β-Aspartylaspartic acid TFA salt | An impurity of L-Ornithine L-aspartate salt which is used as a ligand in targeting SDF-1/CXCL12 with ligands that prevents activation of CXCR4 through structure-based drug design. Group: Pharmaceutical. Alternative Names: β-Aspartylaspartic acid TFA; β-Aspartylaspartic acid trifluoroacetate salt; beta-Asp-Asp TFA salt; (2S)-2-[[(3S)-3-amino-3-carboxypropanoyl]amino]butanedioic acid trifluoroacetate salt. Pack Sizes: 100 mg. Product ID: BAT-016097. Molecular formula: C10H13F3N2O9. Mole weight: 362.21. Custom synthesis is available. Send your inquiries for more information. | London |
| Di-(2-pyridyl)(dicyclohexylphosphino)amine | Di-(2-pyridyl)(dicyclohexylphosphino)amine, a chemical compound often employed in the biomedicine sector, acts as an adept ligand for palladium-catalyzed C-N and C-C bond formation reactions, rendering it especially valuable in the creation of heterocyclic compounds. This product boasts widespread usage in the role of a catalyst and can even be utilized for the treatment of specific strains of cancer, such as breast cancer, owing to its exceptional medicinal characteristics. Group: Pharmaceutical. Alternative Names: N-(Dicyclohexylphosphino)-N-(pyridin-2-yl)pyridin-2-amine. CAS No. 472959-98-1. Pack Sizes: 100 mg. Product ID: B2699-238735. Molecular formula: C22H30N3P. Mole weight: 367.47. Custom synthesis is available. Send your inquiries for more information. | London |
| DSPE-PEG Folate | DSPE-PEG-Folate is a conjugate of folic acid and amino-PEG-DSPE, used for folate-targeted PEGylated liposome preparation. Uses: Dspe-peg-folate incorporated into liposomes serves as a targeting ligand. folate targeted drug delivery is useful in diagnosing and treating cancer and inflammatory diseases. Group: Pharmaceutical. Alternative Names: Folic acid PEG DSPE; 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000/5000]. CAS No. 1236288-25-7. Pack Sizes: 100 mg. Product ID: B1370-051336. Molecular formula: (C2H4O)nC63H104N9O15P. Custom synthesis is available. Send your inquiries for more information. | London |
| Fmoc-Leu-OH | Fmoc-Leu-OH is an amino acid derivative. It is also one of the novel PPARγ ligands that can reduce osteoclasts differentiation through activating PPARγ. Group: Pharmaceutical. Alternative Names: Fmoc-L-Leu-OH; N-(9-fluorenylmethoxycarbonyl)-L-leucine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine; NPC 15199; NPC15199; NPC-15199. CAS No. 35661-60-0. Pack Sizes: 1 kg. Product ID: BAT-008101. Molecular formula: C21H23NO4. Mole weight: 353.42. Custom synthesis is available. Send your inquiries for more information. | London |
| GalNAc-INF7 | GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. INF7 peptide is a glutamine-enriched analogue of the membrane-disruptive segment of HA2 (amino acids 1-23) with greater pH sensitivity. Group: Pharmaceutical. Alternative Names: GalNAc-CGLFEAIEGFIENGWEGMIDGWYG. Pack Sizes: 5 mg. Product ID: B1370-410022. Molecular formula: C189H303N39O70S2. Mole weight: 4305.78. Custom synthesis is available. Send your inquiries for more information. | London |
| GalNac-L96 free base | GalNAC-L96 free base is a triantennary GalNAc ligand that can be used for the synthesis of GalNAC-SiRNA and for the delivery of nucleic acid drugs. GalNAc is a ligand for the asialal glycoprotein receptor (ASGPR). Group: Pharmaceutical. Alternative Names: L-96; Butanedioic acid, 1-[(3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] ester; 1-[(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] butanedioate; GalNAc-L96-SA; L-96-Succinic Acid; GalNAc-L96-Succinate. CAS No. 1159408-61-3. Pack Sizes: 100 mg. Product ID: B1370-427872. Molecular formula: C121H179N11O45. Mole weight: 2507.76. Custom synthesis is available. Send your inquiries for more information. | London |
| JUN68744 | JUN68744 is a useful peptide linker for synthesis of PSMA-617 (vipivotide tetraxetan), which is a ligand used to make 177Lu-PSMA-617, a radioactive molecule to fight cancer. PSMA-617 originally was developed at the German Cancer Research Center and the Heidelberg University Hospital. ABX held the exclusive license to bring the treatment, which targets prostate-specific membrane antigen (PSMA), through early clinical development. Group: Pharmaceutical. Alternative Names: JUN-68744; JUN 68744; PSMA-617-linker; PSMA 617-linker; PSMA617-linker; Vipivotide tetraxetan Linker; (((S)-5-((S)-2-((1r,4S)-4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanamido)-1-carboxypentyl)carbamoyl)-L-glutamic acid. CAS No. 1703768-74-4. Pack Sizes: 100 mg. Product ID: BADC-00615. Molecular formula: C33H45N5O9. Mole weight: 655.74. Custom synthesis is available. Send your inquiries for more information. | London |
| Mirogabalin | This active molecular is an α2δ-1 ligand being developed for pain associated with diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia which related to related to drugs such as gabapentin and pregabalin. Mirogabalin binds to the α2δ calcium channels (1 and 2) and was estimated to be much more potent than pregabalin. In Nov 2015, a Japanese company named Daiichi Sankyo plans a phase III trial for Postherpetic neuralgia and Neuropathic pain (in patients with diabetic peripheral neuropathy and renal impairment) in Japan. In May 2016, Pharmacokinetics and adverse data from a phase I trial in volunteers presented at the 35th Annual Scientific Meeting of the American Pain Society. Uses: Treatment of diabetic peripheral neuropathic pain. Group: Pharmaceutical. Alternative Names: 2-[(1R,5S,6S)-6-(aminomethyl)-3-ethyl-6-bicyclo[3.2.0]hept-3-enyl]acetic acid, DS-5565,CAS#1138245-21-2 ( Mirogabalin besylate). CAS No. 1138245-13-2. Pack Sizes: 25 mg. Product ID: B0084-475092. Molecular formula: C12H19NO2. Mole weight: 209.29. Custom synthesis is available. Send your inquiries for more information. | London |
| N10-(Trifluoroacetyl)pteroic acid | N10-(Trifluoroacetyl)pteroic acid (CAS# 37793-53-6) is a derivative of Pteroic acid (P840110), both of which are used as reagents to synthesize target ligands, like Folic acid (F680300), that have the ability to deliver chemotherapeutic agents specifically to cancer cells. Group: Pharmaceutical. Alternative Names: 4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-(2,2,2-trifluoroacetyl)amino]benzoic acid. CAS No. 37793-53-6. Pack Sizes: 500 mg. Product ID: B0817-114099. Molecular formula: C16H11F3N6O4. Mole weight: 408.29. Custom synthesis is available. Send your inquiries for more information. | London |
| Nociceptin | Nociceptin, a 17 amino acid neuropeptide involved in a variety of biological systems, is the endogenous ligand of the nociceptin receptor, acting as a potent anti-analgesic. Group: Pharmaceutical. Alternative Names: Orphanin FQ; H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH; L-phenylalanyl-glycyl-glycyl-L-phenylalanyl-L-threonyl-glycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-asparagyl-L-glutamine; Nociceptin/orphanin FQ; Nociceptin (1-17); Orphanin FQ (rat, human, swine). CAS No. 170713-75-4. Pack Sizes: 5 mg. Product ID: BAT-006193. Molecular formula: C79H129N27O22. Mole weight: 1809.04. Custom synthesis is available. Send your inquiries for more information. | London |
| Pomalidomide-C2-NH2 | Pomalidomide-C2-NH2 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. Group: Pharmaceutical. Alternative Names: 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; SCHEMBL17884390; TQP0427; Cereblon Ligand-Linker Conjugates 15; HY-128846; Pomalidomide-C2-NH2; Pomalidomide-alkylC2-amine; E3 ligase Ligand 17; 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride. CAS No. 1957235-66-3. Pack Sizes: 25 mg. Product ID: BAT-006493. Molecular formula: C15H16N4O4. Mole weight: 316.31. Custom synthesis is available. Send your inquiries for more information. | London |
| Pomalidomide-PEG3-C2-NH2 hydrochloride | Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker of 3 O(CH2)2 units with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Group: Pharmaceutical. Alternative Names: Cereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride. CAS No. 2446474-09-3. Pack Sizes: 100 mg. Product ID: B2693-052918. Molecular formula: C21H29ClN4O7. Mole weight: 484.93. Custom synthesis is available. Send your inquiries for more information. | London |
| Pomalidomide-PEG5-CO2H | Pomalidomide-PEG5-CO2H is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal carboxylic acid for reactivity with an amine on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Group: Pharmaceutical. Alternative Names: 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid. CAS No. 2139348-63-1. Pack Sizes: 25 mg. Product ID: B2693-285227. Molecular formula: C26H35N3O11. Mole weight: 565.57. Custom synthesis is available. Send your inquiries for more information. | London |
| RGD peptide | RGD peptide is an inhibitor of integrin-ligand interactions. Group: Pharmaceutical. Alternative Names: H-Gly-Arg-Gly-Asp-Asn-Pro-OH; RGD peptide (GRGDNP); glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-asparagyl-L-proline; (S)-1-((6S,12S,15S)-1-amino-15-(2-amino-2-oxoethyl)-6-(2-aminoacetamido)-12-(carboxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecane)pyrrolidine-2-carboxylic acid. CAS No. 114681-65-1. Pack Sizes: 10 mg. Product ID: BAT-006171. Molecular formula: C23H38N10O10. Mole weight: 614.61. Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-2-Amino-2-methyl-4-pentenoic acid | (S)-2-Amino-2-methyl-4-pentenoic acid, an analog of amino acid, serves as a versatile ligand for studying the ionotropic glutamate receptors, besides becoming a precursor for synthesizing diverse natural and unnatural amino acids. With its potential therapeutic effects on neural injury and epilepsy, this compound bears immense significance in the realm of neurological research. Group: Pharmaceutical. Alternative Names: L-alpha-Allylalanine; 4-Pentenoicacid,2-amino-2-methyl-,(2R)-(9CI); L-α-Methylallylalanine; (S)-2-Amino-2-methyl-4-pentenoic acid; L-α-ALLYLALANINE; (R)-alpha-Allylalanine (>98%, >98%ee); H-alpha-All-L-Ala-OH; (R)-2-amino-2-methylpent-4-enoic acid. CAS No. 96886-56-5. Pack Sizes: 100 mg. Product ID: BAT-006499. Molecular formula: C6H11NO2. Mole weight: 129.16. Custom synthesis is available. Send your inquiries for more information. | London |
| [(S)-N-2'-Amino[1,1'-binaphthalen]-2-yl]-4-methylbenzenesulfonamide | N-[(S)-2'-Amino-[1,1'-binaphthalen]-2-yl]-4-methylbenzenesulfonamide is a chiral nitrogen ligand for enantioselective synthesis. Group: Pharmaceutical. Alternative Names: N-[(S)-2'-Amino-[1,1'-binaphthalen]-2-yl]-4-methylbenzenesulfonamide. CAS No. 933782-32-2. Pack Sizes: 1 g. Product ID: B1370-368977. Molecular formula: C27H22N2O2S. Mole weight: 438.54. Custom synthesis is available. Send your inquiries for more information. | London |
| (S,R,S)-AHPC-C10-NH2 dihydrochloride | (S,R,S)-AHPC-C10-NH2 dihydrochloride is a synthetic E3 ligand-linker conjugate containing a von-Hippel-Lindau (VHL) ligand based on (S,R,S)-AHPC and a C10 alkyl linker with terminal amine for covalent binding, which is an intermediate in the synthesis of a PROTAC degradation agent targeting BET. Group: Pharmaceutical. Alternative Names: VH032-C10-NH2 dihydrochloride. CAS No. 2341796-75-4. Pack Sizes: 50 mg. Product ID: B1370-292453. Molecular formula: C33H53Cl2N5O4S. Mole weight: 686.78. Custom synthesis is available. Send your inquiries for more information. | London |
| (S,R,S)-AHPC-Me | E3 ligase Ligand 1A is a VH032 derivate for conjugation reactions of PROTAC, which can hijack VHL as the E3 ubiquitin ligase component. Group: Pharmaceutical. Alternative Names: (S,R,S)-AHPC-Me; VHL ligand 2; E3 ligase Ligand 1A; 1-(2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-[1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide. CAS No. 1948273-02-6. Pack Sizes: 1 g. Product ID: B2693-291831. Molecular formula: C23H32N4O3S. Mole weight: 444.59. Custom synthesis is available. Send your inquiries for more information. | London |
| (S,R,S)-AHPC-PEG2-NH2 hydrochloride | (S,R,S)-AHPC-PEG2-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate consisting of a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Group: Pharmaceutical. Alternative Names: E3 ligase Ligand-Linker Conjugates 6; VHL Ligand-Linker Conjugates 3 hydrochloride. CAS No. 2097973-72-1. Pack Sizes: 100 mg. Product ID: B1370-285252. Molecular formula: C28H42ClN5O6S. Mole weight: 612.18. Custom synthesis is available. Send your inquiries for more information. | London |
| Thalidomide 4'-ether-alkylC2-amine hydrochloride | Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a short C2 alkyl linker with terminal amine for covalent binding, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Group: Pharmaceutical. Alternative Names: Thalidomide - linker 6. CAS No. 2341840-99-9. Pack Sizes: 500 mg. Product ID: B2693-008870. Molecular formula: C15H16ClN3O5. Mole weight: 353.76. Custom synthesis is available. Send your inquiries for more information. | London |
| Thalidomide-O-amido-C6-NH2 (TFA) | Thalidomide-O-amido-C6-Amine trifluoroacetate is a PROTAC block consist of Thalidomide linked to alkyl with Amine functional group for conjugation reactions. Group: Pharmaceutical. Alternative Names: Thalidomide-O-amido-C6-NH2 (TFA); Cereblon Ligand-Linker Conjugates 11 (TFA); E3 Ligase Ligand-Linker Conjugates 25 (TFA); Thalidomide-O-amido-C6-Amine Trifluoroacetate; N-(6-aminohexyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid. CAS No. 1950635-14-9. Pack Sizes: 100 mg. Product ID: B2693-008754. Molecular formula: C23H27F3N4O8. Mole weight: 544.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Thalidomide-O-C4-NH2 hydrochloride | Thalidomide-O-C4-NH2 hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C4 alkyl linker with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Group: Pharmaceutical. Alternative Names: Thalidomide-linker 9. CAS No. 2376990-29-1. Pack Sizes: 100 mg. Product ID: B1370-292464. Molecular formula: C17H20ClN3O5. Mole weight: 381.81. Custom synthesis is available. Send your inquiries for more information. | London |
| TL13-112 | TL13-112 is a potent and selective PROTAC® degrader targeting anaplastic lymphoma kinase (ALK) with an IC50 value of 0.14 nM, consisiting of a cereblon E3 ligase ligand Pomalidomide conjugated to an ALK inhibitor by a linker. Group: Pharmaceutical. Alternative Names: TL 13-112; TL-13-112; N-[2-[2-[2-[4-[4-[[5-Chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]acetamide; N-(2-{2-[2-(4-{4-[(5-Chloro-4-{[2-(isopropylsulfonyl)phenyl]amino}-2-pyrimidinyl)amino]-5-isopropoxy-2-methylphenyl}-1-piperidinyl)ethoxy]ethoxy}ethyl)-N2-[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]glycinamide; Acetamide, N-[2-[2-[2-[4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-. CAS No. 2229037-19-6. Pack Sizes: 5 mg. Product ID: B1370-292444. Molecular formula: C49H60ClN9O10S. Mole weight: 1002.57. Custom synthesis is available. Send your inquiries for more information. | London |
| TL13-12 | TL13-12 is a potent PROTAC® degrader targeting anaplastic lymphoma kinase (ALK) with an IC50 value of 0.69 nM, consisiting of a cereblon E3 ligase ligand Pomalidomide conjugated to an ALK inhibitor by a linker. Group: Pharmaceutical. Alternative Names: TL 13-12; TL-13-12; Acetamide, N-[2-[2-[2-[4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-3-methoxyphenyl]-1-piperazinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-; N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamide. CAS No. 2229037-04-9. Pack Sizes: 5 mg. Product ID: B1370-292442. Molecular formula: C45H53ClN10O10S. Mole weight: 961.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Tri-GalNAc(OAc)3 | Tri-GalNAc(OAc)3 is a modified glycosylated compound that features three N-acetylgalactosamine (GalNAc) units, and is typically provided as a trifluoroacetic acid (TFA) salt. This structure enhances the compound's solubility and stability, making it suitable for use in various biological applications, including drug delivery and targeted therapeutics. The presence of multiple acetyl groups can improve the bioavailability and cellular uptake of the compound, while the tri-GalNAc configuration allows for specific interactions with receptors, particularly in the context of glycoengineering and the development of therapies for conditions like cancer and genetic disorders. It is a molecular building block belonging to the GalNAc series or related delivery systems. Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. Group: Pharmaceutical. Alternative Names: Peracetylated GalNAc-L96-Amine; Peracetylated tri-GalNAc-amine; 6-Amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy. CAS No. 1159408-64-6. Pack Sizes: 25 mg. Product ID: B1370-098387. Molecular formula: C79H128N10O36. Mole weight: 1793. | London |
| Tri-GalNAc(OAc)3 TFA | Tri-GalNAc(OAc)3 TFA is a modified glycosylated compound that features three N-acetylgalactosamine (GalNAc) units, and is typically provided as a trifluoroacetic acid (TFA) salt. This structure enhances the compound's solubility and stability, making it suitable for use in various biological applications, including drug delivery and targeted therapeutics. The presence of multiple acetyl groups can improve the bioavailability and cellular uptake of the compound, while the tri-GalNAc configuration allows for specific interactions with receptors, particularly in the context of glycoengineering and the development of therapies for conditions like cancer and genetic disorders. It is a molecular building block belonging to the GalNAc series or related delivery systems. Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. Group: Pharmaceutical. Alternative Names: Peracetylated tri-GalNAc-amine TFA salt; 4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galac. CAS No. 1159408-65-7. Pack Sizes: 100 mg. Product ID: B1370-427874. Molecular formula: C81H129F3N10O38. Mole we | London |
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