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| Product | Description | |
|---|---|---|
| Amarogentin | Amarogentin exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways and displays immunomodulatory effects in human mast cells and keratinocytes. It inhibits the growth of SNU-16 human gastric cancer cells (IC50 = 12.4 μM) and increases apoptosis when used at a concentration of 50 μM. Amarogentin dose-dependently reduces tumor growth in a SNU-16 nude mouse xenograft model. Amarogentin may offer therapeutic potential for preventing or treating thromboembolic disorders, it prevents platelet activation through the inhibition of PLC γ2-PKC cascade and MAPK pathway. Group: Pharmaceutical. Alternative Names: sweroside-2'-(3'',5'',3'''-trihydroxydiphenyl)-2''-carboxylic acid ester; (4aS)-6α-[2-O-[(3,3',5-Trihydroxy-1,1'-biphenyl-2-yl)carbonyl]-β-D-glucopyranosyloxy]-5β-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one. CAS No. 21018-84-8. Pack Sizes: 50 mg. Product ID: B1370-062768. Molecular formula: C29H30O13. Mole weight: 586.54. Custom synthesis is available. Send your inquiries for more information. |  London |
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