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12α-Hydroxygrandiflorenic acid is a diterpenoid compound found in the herbs of Wedelia trilobata. Group: Pharmaceutical. CAS No. 63768-17-2. Pack Sizes: 5 mg. Product ID: NP1740. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
14β,16β-Dihydroxy-3β-(β-D-glucopyranosyloxy)-5α-bufa-20,22-dienolide is a remarkable natural compound renowned for its immense potential in studying an array of ailments such as cancer, inflammation and cardiovascular maladies. By proficiently deterring neoplastic proliferation and instigating apoptosis, this natural compound exhibits unyielding anticancer prowess. Group: Pharmaceutical. CAS No. 1323952-04-0. Pack Sizes: 1 mg. Product ID: NP6156. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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16α-Hydroxydehydrotrametenolic acid
16α-Hydroxydehydrotrametenolic acid is a triterpene carboxylic acid isolated from the sclerotium of Poria cocos(Schw.)Wolf. Group: Pharmaceutical. CAS No. 176390-66-2. Pack Sizes: 5 mg. Product ID: B0005-053953. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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16α-Hydroxytrametenolic acid
16α-Hydroxytrametenolic acid is a triterpene carboxylic acid isolated from the sclerotium of Poria cocos(Schw.)Wolf. 16α-Hydroxytrametenolic acid is suggested to inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema. Group: Pharmaceutical. CAS No. 176390-68-4. Pack Sizes: 5 mg. Product ID: B0005-053950. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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1α-Hydroxy VD4
1α-Hydroxy VD4 is an analogue of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Group: Pharmaceutical. CAS No. 143032-85-3. Pack Sizes: 1 mg. Product ID: B1959-054064. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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2α,9α,11-Trihydroxy-6-oxodrim-7-ene
2α,9α,11-Trihydroxy-6-oxodrim-7-ene is produced from the culture medium of the marine-derived fungus Aspergillus insuetus. Group: Pharmaceutical. CAS No. 1175543-03-9. Pack Sizes: 1 mg. Product ID: BBF-04370. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
3α-Cinnamoyloxy-9β,17-dihydroxy-ent-kaur-15-en-19-oic acid, a naturally occurring compound, has demonstrated promising anti-tumor efficacy in preclinical assays. Its potential as a therapeutic option for multiple malignancies, such as prostate and breast cancer, is currently under investigation. The compound shows immense potential as a potent anti-cancer agent, warranting further research to determine its clinical utility. Group: Pharmaceutical. CAS No. 2186648-60-0. Pack Sizes: 5 mg. Product ID: NP1366. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Isorauhimbine is isolated from the root of Rauvolfia serpentina. Group: Pharmaceutical. CAS No. 483-09-0. Pack Sizes: 5 mg. Product ID: NP0399. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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3-O-Acetyl-16α-hydroxytrametenolic acid
3-O-Acetyl-16α-hydroxytrametenolic acid is a triterpene isolated from the sclerotium of Poria cocos(Schw.)Wolf. It has the inhibitory effect on AAPH-induced hemolysis of red blood cells and 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. Group: Pharmaceutical. CAS No. 168293-13-8. Pack Sizes: 5 mg. Product ID: B0005-053911. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Vallesamine N-oxide is isolated from the leaves of Alstonia scholaris. Group: Pharmaceutical. CAS No. 126594-73-8. Pack Sizes: 2 mg. Product ID: NP0329. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
6β-(Hexa-2,4-dienoyloxy)-9α,12-dihydroxydrimenol is produced in the cultures of the fungus Penicillium sp. Group: Pharmaceutical. CAS No. 1136245-81-2. Pack Sizes: 1 mg. Product ID: BBF-04413. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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7α,15-Dihydroxydehydroabietic acid
7α,15-Dihydroxydehydroabietic acid is extracted from the caulis and leaves of Callicarpa kochiana. It has significant cytotoxic activity. Group: Pharmaceutical. CAS No. 155205-64-4. Pack Sizes: 1 mg. Product ID: NP1683. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
8α-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate is a natural diterpenoid found in the herbs of Metasequoia glyptostroboides. Group: Pharmaceutical. CAS No. 117254-98-5. Pack Sizes: 1 mg. Product ID: NP1687. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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9-Hydroxy-α-lapachone
9-Hydroxy-α-lapachone isolated from the herbs of Catalpa ovata. It exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase. Uses: Potent inhibitory activity. Group: Pharmaceutical. CAS No. 22333-58-0. Pack Sizes: 1 mg. Product ID: NP4466. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
β-D-Glucopyranoside, (3β, 6α, 16β, 20R, 24S)-3-[(3, 4-di-O-acetyl-β-D-xylopyranosyl)oxy]-20, 24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Group: Pharmaceutical. CAS No. 1324005-51-7. Pack Sizes: 5 mg. Product ID: B0005-465737. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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DL-α-Hydroxystearic acid
2-Hydroxyoctadecanoic acid is a natural product found in Allamanda cathartica, Brassica napus, and other organisms. It plays a crucial role as an intermediate in the production of several other fatty acids, such as linoleic acid, oleic acid, and arachidonic acid. Group: Pharmaceutical. CAS No. 629-22-1. Pack Sizes: 500 mg. Product ID: B1370-190468. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
ent-11α,15α-Dihydroxykaur-16-en-19-oic acid is a natural diterpenoid found in the herbs of Cerbera manghas. Group: Pharmaceutical. CAS No. 57719-76-3. Pack Sizes: 5 mg. Product ID: NP1318. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
ent-11,16-Epoxy-15-hydroxykauran-19-oic acid is isolated from the herbs of Nouelia insignis. Group: Pharmaceutical. CAS No. 77658-46-9. Pack Sizes: 5 mg. Product ID: NP1717. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
ent-11α-Hydroxyabieta-8(14),13(15)-dien-16,12α-olide is extracted from the roots of Euphorbia ebracteolata. It has significant cytotoxic activity against Jurkat and ANA-1 cells with IC50 values 1.79 x 10(-2) and 7.12 x 10(-3) microM. Group: Pharmaceutical. CAS No. 130466-20-5. Pack Sizes: 1 mg. Product ID: NP1424. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
ent-6,9-Dihydroxy-15-oxokaur-16-en-19-oic acid β-D-glucopyranosyl ester is isolated from the herbs of Pteris semipinnata. Group: Pharmaceutical. CAS No. 81263-98-1. Pack Sizes: 5 mg. Product ID: NP1238. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
5g Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C19H30O2. CAS No. 481-29-8. Prepack ID : 38816451-5g. Molecular Weight : 290.44.
Hydroxy-alpha-sanshool
Hydroxy-alpha-sanshool is a compound isolated from the genus Zanthoxylum. It stimulates D-hair afferent nerve fibers. Group: Pharmaceutical. CAS No. 83883-10-7. Pack Sizes: 5 mg. Product ID: B0005-008250. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
β-Yohimbine isolated from the peel of Corynante yohimbe. Uses: Anti-plasmodial and anti-malarial activity. Group: Pharmaceutical. CAS No. 549-84-8. Pack Sizes: 1 mg. Product ID: NP0427. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Methyl 7α,15-dihydroxydehydroabietate
Methyl 7α,15-dihydroxydehydroabietate is extracted from the barks of Pinus yunnanensis. Group: Pharmaceutical. CAS No. 155205-65-5. Pack Sizes: 1 mg. Product ID: NP1716. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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4',6,7-Trihydroxyisoflavone
4',6,7-Trihydroxyisoflavone is an isoflavone isolated from the seeds of Glycine max with antioxidant activity. It is also a novel inhibitor of PKCα that suppresses solar UV-induced matrix metalloproteinase 1. Group: Pharmaceutical. CAS No. 17817-31-1. Pack Sizes: 5 mg. Product ID: B0005-395761. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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4-Hydroxyisoleucine
4-Hydroxyisoleucine, which comes from the seeds of Trigonella foenum-graecum L, could inhibit palmitate-induced, ROS-associated inflammation and restored insulin sensitivity through regulating IRS-1 function. It acts to improve insulin resistance by promoting mitochondrial biogenesis in high fructose diet fed STZ induced diabetic rats. Besides, 4-Hydroxyisoleucine could remarkably improve high glucose-induced IR in 3T3-L1 adipocytes. Meanwhile, 4-HIL could inhibit the secretion of TNF-alpha. Group: Pharmaceutical. CAS No. 781658-23-9. Pack Sizes: 100 mg. Product ID: B0005-347850. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetylcorynoline
Acetylcorynoline, which can be extracted from the tubers of Corydalis ambigua, inhibits the maturing of bone marrow-derived dendritic cells in mice. However, it is only cytotoxic in amounts of greater than 20 μM. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; prevents α-synuclein aggregation; recovers lipid content in OW13 strain; restores food-sensing behavior, and dopamine levels; and prolongs life-span in 6-hydroxydopamine-treated N2 strain, thus showing its potential as a possible antiparkinsonian drug. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Uses: Antifungal/anti-inflammatory. Group: Pharmaceutical. CAS No. 18797-80-3. Pack Sizes: 10 mg. Product ID: B2703-464490. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Chamaechromone
Chamaechromone is isolated from the roots of Stellera chamaeja sme. Chamaechromone can undergo extensive phase I and phase II metabolism in rat. Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by α-naphthoflavone, and predominantly catalyzed by recombinant human cytochrome P450 1A2. Group: Pharmaceutical. CAS No. 93413-00-4. Pack Sizes: 5 mg. Product ID: NP2301. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Disodium (R)-2-Hydroxyglutarate
Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. In U-87MG cells, (R)-2-Hydroxyglutarate acts as a weak antagonist of α-KG to inhibit α-KG-dependent histone demethylases and increase dimethylation on both H3K9 and H3K79. Group: Pharmaceutical. CAS No. 103404-90-6. Pack Sizes: 100 mg. Product ID: BAT-008968. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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DMOG
DMOG is an antagonist of α-ketoglutarate cofactor and inhibitor for HIF prolyl hydroxylase. Group: Pharmaceutical. CAS No. 89464-63-1. Pack Sizes: 1 g. Product ID: B1370-140847. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Doxercalciferol
Doxercalciferol (Hectorol; 1.alpha.-Hydroxyvitamin D2) is a synthetic analog of vitamin D; is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA). Group: Pharmaceutical. CAS No. 54573-75-0. Pack Sizes: 25 mg. Product ID: B1959-485206. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Estrone
Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum concentrations of estrone in premenopausal women fluctuate according to the menstral cycle and becomes the most predominant estrogen in postmenopausal women. The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol. Group: Pharmaceutical. CAS No. 53-16-7. Pack Sizes: 50 g. Product ID: NP6101. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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L-α-Methyltyrosine
L-α-Methyltyrosine is a tyrosine hydroxylase inhibitor. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. It reduces the elevated levels of catecholamines associated with pheochromocytoma, thus preventing hypertension. It significantly inhibits COX-2 activity and has anti-inflammatory and anti-ulcer effects. Uses: L-α-methyltyrosine is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. Group: Pharmaceutical. CAS No. 672-87-7. Pack Sizes: 5 g. Product ID: BAT-008124. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Lophanthoidin E
Lophanthoidin E, also called (6β,7α)-6,7,12-Trihydroxy-11,14-dioxoabieta-8,12-dien-16-yl aceta te, is a natural diterpenoid found in the herbs of Rabdosia lophanthoides. Group: Pharmaceutical. CAS No. 120462-45-5. Pack Sizes: 1 mg. Product ID: NP1228. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Metaraminol Bitartrate
Metaraminol is a stereoisomer of meta-hydroxynorephedrine, acting as an adrenergic agonist that increases both systolic and diastolic blood pressure. It can be used in the prevention and treatment of hypotension, particularly as a complication of anesthesia. Uses: Adrenergic alpha-1 receptor agonists. Group: Pharmaceutical. CAS No. 33402-03-8. Pack Sizes: 10 g. Product ID: B2693-066359. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N-Boc-O-(mesitylsulfonyl)hydroxylamine
N-Boc-O-(mesitylsulfonyl)hydroxylamine (CAS# 36016-39-4) is a useful reagent for the enantioselective aziridination of α,β-unsaturated aldehydes. Group: Pharmaceutical. CAS No. 36016-39-4. Pack Sizes: 25 g. Product ID: BB022831. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Rosthornin A
Rosthornin A, also called (5β, 8α, 9β, 10α, 11β, 13α)-13, 18-Dihydroxy-15-oxokaur-16-en-11-yl ace tate, is a natural diterpenoid found in the herbs of Rabdosia rosthornii. Group: Pharmaceutical. CAS No. 125164-55-8. Pack Sizes: 1 mg. Product ID: NP1229. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Rosthornin B
Rosthornin B, also called (5β, 7α, 8α, 9β, 10α, 11β, 13α)-7, 13-Dihydroxy-15-oxokaur-16-ene-11, 18- diyl diacetate, is a natural diterpenoid found in the herbs of Rabdosia rosthornii. Group: Pharmaceutical. CAS No. 125181-21-7. Pack Sizes: 1 mg. Product ID: NP1242. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Secalciferol
Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification. lt mediates calcium and phosphorus homeostasis and inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. lt also can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Uses: Bone density conservation agents. Group: Pharmaceutical. CAS No. 55721-11-4. Pack Sizes: 1 mg. Product ID: B0084-375020. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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SKF-86002
SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Group: Pharmaceutical. CAS No. 72873-74-6. Pack Sizes: 300 mg. Product ID: B0084-195907. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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SR3335
The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation activity (IC50 = 480 nM). It has no effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor &alpha. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis. Group: Pharmaceutical. CAS No. 293753-05-6. Pack Sizes: 50 mg. Product ID: B2693-458981. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Triptoquinone B
Triptoquinone B, also called 19-Hydroxy-8,12-abietadiene-3,11,14-trione, is a natural diterpenoid found in the vines of Tripterygium wilfordii. 19-Hydroxy-8,12-abietadiene-3,11,14-trione is a novel interleukin-1 inhibitor, shows extremely potent inhibitory activities against interleukin-lα and β releases for human peripheral mononticlear cells. Group: Pharmaceutical. CAS No. 142937-50-6. Pack Sizes: 1 mg. Product ID: NP1268. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ursocholic acid
Ursocholic acid plays a role as a human urinary metabolite and a 7alpha-hydroxysteroid dehydrogenase inhibitor. Uses: Ursodeoxycholic acid (u850000) impurity. Group: Pharmaceutical. CAS No. 2955-27-3. Pack Sizes: 100 mg. Product ID: B1370-264335. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N-methyl-5,6-dihydroxyindole
An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Group: Pharmaceutical. CAS No. 4821-00-5. Pack Sizes: 100 mg. Product ID: B1370-078100. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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