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5-HT3 antagonist 5 is a 5-HT3 receptor antagonist with anti-depressant activity. Group: Pharmaceutical. CAS No. 901599-43-7. Pack Sizes: 50 mg. Product ID: B1370-186731. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Antagonist G
Antagonist G is a substance P analog, which is a broad spectrum neuropeptide growth factor antagonist and antiproliferative agent. It was developed for the treatment of small cell lung cancer. It could inhibit neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro. It also inhibits growth of SCLC xenografts in mice in vivo. It blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. It activates JNK and stimulates apoptosis. It is an anticancer agent and is resistant to degradation by peptidases. Group: Pharmaceutical. CAS No. 115150-59-9. Pack Sizes: 1 mg. Product ID: BAT-006104. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
TLR7/8 agonist 1
TLR7/8 agonist 1 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It exhibits prominent immunostimulatory activities. Group: Pharmaceutical. CAS No. 1258457-59-8. Pack Sizes: 100 mg. Product ID: B2693-009945. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
TLR7/8 agonist 1 dihydrochloride
TLR7/8 agonist 1 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It exhibits prominent immunostimulatory activities. Group: Pharmaceutical. CAS No. 1620278-72-9. Pack Sizes: 100 mg. Product ID: B2693-009887. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Group: Pharmaceutical. CAS No. 52144-90-8. Pack Sizes: 100 mg. Product ID: B1712-284935. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
13-trans-Latanoprost
17-phenyl trinor PGF2α is a potent FP receptor agonist. Group: Pharmaceutical. CAS No. 130209-76-6. Pack Sizes: 100 mg. Product ID: B2693-072499. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. CAS No. 1227626-50-7. Pack Sizes: 100 mg. Product ID: B0176-284898. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
One of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It is a prescription drug used to treat cigarette addiction. Group: Pharmaceutical. CAS No. 357424-12-5. Pack Sizes: 10 mg. Product ID: B2694-039627. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
15-Keto Travoprost
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. CAS No. 404830-45-1. Pack Sizes: 25 mg. Product ID: B1911-313687. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1,5-methano-1H-3-benzazepine
1,5-methano-1H-3-benzazepine is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It is a prescription drug used to treat cigarette addiction. Group: Pharmaceutical. CAS No. 230615-59-5. Pack Sizes: 1 g. Product ID: B2694-342826. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. CAS No. 1418133-29-5. Pack Sizes: 100 mg. Product ID: B0176-284894. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. CAS No. 1882095-50-2. Pack Sizes: 100 mg. Product ID: B0027-284940. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
2-[2,6-Dimethyl-4-[3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid is a racemic compound of Elafibranor, a dual PPARα/δ agonist that has demonstrated efficacy in disease models of nonalcoholic fatty liver disease (NAFLD)/NASH and liver fibrosis. Group: Pharmaceutical. CAS No. 824932-88-9. Pack Sizes: 50 mg. Product ID: B0084-474857. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine-7,8-diamine is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Group: Pharmaceutical. CAS No. 808120-35-6. Pack Sizes: 10 mg. Product ID: B1370-342922. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is an intermediate in the synthesis of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. CAS No. 150026-75-8. Pack Sizes: 100 mg. Product ID: B0052-208484. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2-Amino-3'-O-(2-methoxyethyl)adenosine
2-Amino-3'-O-(2-methoxyethyl)adenosine, a highly potent adenosine receptor agonist, finds extensive utility in biomedical research. Esteemed for its exceptional capabilities, this compound demonstrates remarkable promise in combating diverse ailments. Group: Pharmaceutical. CAS No. 256224-02-9. Pack Sizes: 100 mg. Product ID: B2000-242149. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
One impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Group: Pharmaceutical. CAS No. 882066-15-1. Pack Sizes: 10 mg. Product ID: B2694-338821. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Group: Pharmaceutical. CAS No. 52144-92-0. Pack Sizes: 100 mg. Product ID: B1712-284933. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Group: Pharmaceutical. CAS No. 52144-93-1. Pack Sizes: 100 mg. Product ID: B1712-284934. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2-Bromo-3',5'-dibenzyloxyacetphenone
An impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Group: Pharmaceutical. CAS No. 28924-18-7. Pack Sizes: 100 mg. Product ID: B1712-117930. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2'-MeCCPA
2'-MeCCPA is a potent and highly selective agonist at A1 adenosine receptors (Ki= 3.3, 9580, 37600 and 1150 nM for human recombinant A1, A2A, A2B and A3 receptors respectively). Group: Pharmaceutical. CAS No. 205171-12-6. Pack Sizes: 10 mg. Product ID: B1370-115137. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
[2-(Methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide, an innovative pharmaceutical compound, plays a pivotal role in addressing a myriad of diseases by selectively modulating intricate cellular mechanisms. As an effective antagonist of key enzymes involved in the pathogenesis of malignant tumors, it is widely used in antimicrobial drug development. Group: Pharmaceutical. CAS No. 3637-26-1. Pack Sizes: 1 kg. Product ID: B1370-091081. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2-Propylsulfanyl-pyrimidin-4-ol
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. CAS No. 54460-95-6. Pack Sizes: 100 mg. Product ID: B0027-284937. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid
(2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid, an essential substrate in the preparation of assorted biologically active molecules, is a formidable entity. This compound finds extensive utility as a chiral intermediate in the production of pharmacological agents with specific molecular arrangements. The synthetic derivatives of this intermediate exhibit GABA agonist and dopamine agonist activities with significant implications in managing pathologies related to Alzheimer's, Parkinson's and schizophrenia. Group: Pharmaceutical. CAS No. 4298-8-2. Pack Sizes: 100 mg. Product ID: B2699-117825. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Bepotastine besylate, a histamine H1 receptor antagonist that has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus. Group: Pharmaceutical. CAS No. 210095-58-2. Pack Sizes: 50 g. Product ID: B2694-014533. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of BAR-501 which is a selective GPBAR1 agonist devoid of any FXR agonistic activity. Group: Pharmaceutical. CAS No. 1632118-70-7. Pack Sizes: 10 mg. Product ID: B1662-482217. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
3-Hydroxy agomelatine-[d3]
3-Hydroxy agomelatine-[d3] is an isotope labelled compound of 3-Hydroxyagomelatine which is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM. Group: Pharmaceutical. CAS No. 1079774-23-4. Pack Sizes: 10 mg. Product ID: BLP-013596. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
3-Keto Fenretinide
A derivative of Fenretinide. Fenretinide is a synthetic retinoid agonist. Group: Pharmaceutical. CAS No. 865536-65-8. Pack Sizes: 50 mg. Product ID: B0919-099444. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
4-(2-Bromoacetyl)phenyl acetate
An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Group: Pharmaceutical. CAS No. 41104-10-3. Pack Sizes: 25 mg. Product ID: B2694-331237. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An intermediate of Ropinirole. Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Group: Pharmaceutical. CAS No. 120427-95-4. Pack Sizes: 100 mg. Product ID: B2694-055636. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
4-Benzyl Albuterol
An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Group: Pharmaceutical. CAS No. 56796-66-8. Pack Sizes: 200 mg. Product ID: B2694-126103. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
4-Chloro-2-propylsulfanyl-pyrimidine
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. CAS No. 1351990-36-7. Pack Sizes: 100 mg. Product ID: B0027-284938. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
4-Chloro-N,N-dipropylbenzamide
The TRPA1 receptor agonist 4-Chloro-N,N-dipropylbenzamide has garnered attention for its potential therapeutic applications in pain and inflammation treatment. The compounds' promising effects on migraines and neuropathic pain have been extensively studied. Its unique properties hold immense potential for the development of novel treatments for these conditions. Group: Pharmaceutical. CAS No. 2447-87-2. Pack Sizes: 50 mg. Product ID: B0001-284758. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
4-IBP
4-IBP, an agonist that specially targets sigma receptor (IC50= 1.7 nM), induced marked concentration-dependent decreases in the growth of human cancer cells. Group: Pharmaceutical. CAS No. 155798-08-6. Pack Sizes: 100 mg. Product ID: B2693-474615. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(±)-4-O-Ethyl Albuterol
An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Group: Pharmaceutical. CAS No. 2387728-91-6. Pack Sizes: 100 mg. Product ID: B2694-479414. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
5-(2-Chlorobenzyl)thieno(3,2-C)pyridinium chloride is an impurity of Ticlopidine, a reversible P2Y12 receptor antagonist used to decrease the risk of stroke in patients known to have atherosclerosis. Group: Pharmaceutical. CAS No. 53885-64-6. Pack Sizes: 25 mg. Product ID: B1370-469260. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione is an impurity of Pioglitazone, a PPAR agonist that has antidiabetic activity in patients with type 2 diabetes mellitus. Group: Pharmaceutical. CAS No. 144809-28-9. Pack Sizes: 100 mg. Product ID: NP3434. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Group: Pharmaceutical. CAS No. 152708-24-2. Pack Sizes: 25 mg. Product ID: B2694-376321. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
5-(4-Chlorobenzylidene)-2,4-thiazolidinedione
5-(4-Chlorobenzylidene)-2,4-thiazolidinedione, a well-researched organic compound, exhibits remarkable promise in treating diabetes mellitus type 2 owing to its ability to function as an agonist for peroxisome proliferator-activated receptor gamma (PPAR-γ). PPAR-γ is implicated in the modulation of glucose and lipid metabolism. Beyond its anti-diabetic attributes, this compound has been the subject of inquiry for its potential anti-cancer properties. The chemical's therapeutic significance is evidenced by the numerous investigations conducted on its biological activity. Group: Pharmaceutical. CAS No. 24138-83-8. Pack Sizes: 50 mg. Product ID: B0001-284763. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Prasugrel. Prasugrel is a platelet inhibitor and an irreversible antagonist of P2Y12ADP receptors that prevents the formation of blood clots. It was appoved for the treatment of acute coronary syndrome (ACS), and some cardiovascular diseasess in combination with Aspirin. Group: Pharmaceutical. CAS No. 1373350-61-8. Pack Sizes: 20 mg. Product ID: B0219-007244. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
5-Hydroxy Albuterol
An impurity of Levalbuterol. Levalbuterol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Group: Pharmaceutical. CAS No. 182676-90-0. Pack Sizes: 10 mg. Product ID: B2694-302184. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
5-methoxyuridine
5-Methoxyuridine is an analog of Uridine and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist. Group: Pharmaceutical. CAS No. 35542-01-9. Pack Sizes: 50 mg. Product ID: B2706-111772. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Group: Pharmaceutical. CAS No. 1040405-56-8. Pack Sizes: 100 mg. Product ID: B0176-284897. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
6-Keto Fulvestrant
6-Keto Fulvestrant is an impurity of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B2694-471908. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Group: Pharmaceutical. CAS No. 2059954-32-2. Pack Sizes: 100 mg. Product ID: B0461-284942. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
7-(4-Chlorobutoxy)quinolin-2(1H)-one
An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Group: Pharmaceutical. CAS No. 913613-82-8. Pack Sizes: 100 mg. Product ID: B0461-116115. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. Varenicline is a nicotinic receptor partial agonist. Group: Pharmaceutical. CAS No. 230615-70-0. Pack Sizes: 50 mg. Product ID: B2694-014620. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
8-Deschloro-8-bromo-N-methyl Desloratadine
8-Deschloro-8-bromo-N-methyl Desloratadine is one of Loratadine derivatives. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Group: Pharmaceutical. CAS No. 130642-57-8. Pack Sizes: 25 mg. Product ID: B1370-118732. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
A 1120
A 1120 is a retinol-binding protein 4 (RBP4) antagonist (Ki = 8.3 nM) that can reduce serum RBP4 and retinol, and displaces transthyretin (TTR) from RBP4-TTR complexes. Group: Pharmaceutical. CAS No. 1152782-19-8. Pack Sizes: 100 mg. Product ID: B1370-271974. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
A 71915
A 71915 is a highly potent and competitive natriuretic peptide receptor A (NPRA) antagonist (pKi = 9.18). Group: Pharmaceutical. CAS No. 132956-87-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015128. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
A 779
A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor) (IC50 = 0.3 nM) with no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. Group: Pharmaceutical. CAS No. 159432-28-7. Pack Sizes: 10 mg. Product ID: BAT-006218. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
A 779 TFA
A 779 TFA is a potent angiotensin (1-7) receptor antagonist. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016355. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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AB928
AB928 is a dual antagonist of the A2aR and A2bR adenosine receptors with Kb of 1.5 and 2.0 nM, respectively. It potently blocks the immunosuppressive effects of high adenosine concentrations in the tumor microenvironment. Group: Pharmaceutical. CAS No. 2239273-34-6. Pack Sizes: 50 mg. Product ID: B2693-334167. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Abarelix
Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Group: Pharmaceutical. CAS No. 183552-38-7. Pack Sizes: 10 mg. Product ID: BAT-006166. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
ABT 263-[d8]
ABT 263-[d8] is a labelled ABT 263. ABT 263, also named Navitoclax, is an orally active, synthetic small molecule and an antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. Group: Pharmaceutical. CAS No. 1217620-38-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003186. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
ABT 724 trihydrochloride
ABT 724 trihydrochloride is a potent dopamine D4 receptor partial agonist (EC50 = 12.4 nM; 61% efficacy vs. dopamine) for treatment of sexual dysfunction. Group: Pharmaceutical. CAS No. 587870-77-7. Pack Sizes: 100 mg. Product ID: B2693-375680. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
AC 187
AC 187 is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo. Group: Pharmaceutical. CAS No. 151804-77-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-010348. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
AC 187 acetate
AC 187 acetate is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels, and increases food intake in vivo. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016307. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
AC-55541
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist which displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. It activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. It was well absorbed when administered intraperitoneally to rats, reaching micromolar peak plasma concentrations. It was stable to metabolism by liver microsomes and maintained sustained exposure in rats. Uses: Ac-55541 stimulates cell proliferation, phosphatidylinositol hydrolysis, and calcium mobilization. Group: Pharmaceutical. CAS No. 916170-19-9. Pack Sizes: 300 mg. Product ID: B0084-271988. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acamprosate Calcium
Acamprosate calcium is a gamma-aminobutyric acid(GABA)agonist and modulator of glutamatergic systems. It has been used in alcohol dependence treatments and may be an effective augmentation therapy in patients with treatment-resistant anxiety. It has low bioavailability, but also has an excellent tolerability and safety profile. It is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so it can be administered to patients with hepatitis or liver disease and to patients who continue drinking alcohol. It was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Uses: Alcohol deterrents. Group: Pharmaceutical. CAS No. 77337-73-6. Pack Sizes: 10 g. Product ID: B1370-076955. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acamprosate Calcium-[d12]
Acamprosate Calcium-[d12] is a labelled analogue of Acamprosate Calcium. Acamprosate calcium is a gamma-aminobutyric acid (GABA) agonist and modulator of glutamatergic systems. It has been used in alcohol-dependent treatments and may be an effective augmentation therapy in patients with treatment-resistant anxiety. It has low bioavailability, but also has an excellent tolerability and safety profile. It is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so it can be administered to patients with hepatitis or liver disease and to patients who continue drinking alcohol. It was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003189. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2 is a full competitive MCH-1 receptor antagonist and has no agonist effect on human MCH-1 receptor even at micromolar concentrations (Kb = 3.6 nM). Group: Pharmaceutical. CAS No. 353487-64-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015327. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ac-D-phenylglycinol
Amino acid antagonist. Group: Pharmaceutical. CAS No. 78761-26-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-002629. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acebutolol-[d5]
Acebutolol-[d5] is the labelled analogue of Acebutolol, which is a β-adrenergic receptor antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. Group: Pharmaceutical. CAS No. 1189500-68-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-013703. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Aceclidine-[d3] Hydrochloride
Aceclidine-[d3] Hydrochloride is an isotopic labelled hydrochloride form of Aceclidine. Aceclidine is an agonist of muscarinic receptors. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003192. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acenocoumarol-[d4]
Acenocoumarol-[d4] is a labelled Acenocoumarol. Acenocoumarol, a derivative of coumarin, is an anticoagulant and a Vitamin K antagonist. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003197. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acenocoumarol-[d5]
Acenocoumarol-[d5] is a labelled Acenocoumarol. Acenocoumarol, a derivative of coumarin, is an anticoagulant and a Vitamin K antagonist. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003198. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acepromazine-[d6]
Acepromazine-[d6] is an isotope compound of Acepromazine. Acetylpromazine is a phenothiazine derivative. It has depressant effect on the central nervous system and is used in the treatment of psychoses. It is now almost exclusively used on animals as a sedative and antiemetic. It is used primarily as a chemical restraint in hyperactive or fractious animals. It acts as a dopamine receptor antagonist in the central nervous system, thus causing sedation, muscular relaxation and a reduction in spontaneous activity. It acts as an antagonist on different postsysnaptic receptors - on dopaminergic receptors, on serotonergic receptors, on histaminergic receptors and so on. Group: Pharmaceutical. CAS No. 1173147-97-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003199. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acetyl-Amylin (8-37) (human)
Acetyl-Amylin (8-37) (human) is a most effective amylin antagonist, but its ability to block CGRP inhibition is limited. It completely reverses the inhibitory effect of IAPP on 14C-glycogen accumulation in vitro. Group: Pharmaceutical. CAS No. 178603-79-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015123. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acetylaszonalenin
Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes. It acts as an antagonist of neurokinin-1 (NK1) receptor. Group: Pharmaceutical. CAS No. 42230-55-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-04519. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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