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| Product | Description | |
|---|---|---|
| Agomelatine | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H17NO2. CAS No. 138112-76-2. Prepack ID : 54855684-1g. Molecular Weight : 243.3. |  |
| Agomelatine | Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Group: Pharmaceutical. CAS No. 138112-76-2. Pack Sizes: 20 g. Product ID: NP3699. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Agomelatine-[d3] | Agomelatine-[d3] is the labelled analogue of Agomelatin, which is a melatoninergic agonist and selective 5-HT2C receptor antagonist. It is used as an atypical antidepressant in the treatment of major depressive disorder. Group: Pharmaceutical. CAS No. 1079389-38-0. Pack Sizes: 5 mg. Product ID: BLP-009578. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agomelatine Impurities | Agomelatine Impurities hold critical importance in the biomedical spectrum, instrumental for evaluating the antidepressant Agomelatine's quality and safety metrics. Engaging in stringent analytical and formulation research, these impurities underscore the drug's efficacy in managing major depressive disorders, establishing themselves as essential elements in pharmaceutical quality assurance practices. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Hydroxy agomelatine-[d3] | 3-Hydroxy agomelatine-[d3] is an isotope labelled compound of 3-Hydroxyagomelatine which is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM. Group: Pharmaceutical. CAS No. 1079774-23-4. Pack Sizes: 10 mg. Product ID: BLP-013596. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tasimelteon | Tasimelteon (trade name Hetlioz) is a drug approved by the FDA solely for the treatment of non-24-hour sleep-wake disorder (often designated as N24HSWD) in totally blind adults. It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, similar to other members of the melatonin receptor agonist class of which ramelteon (2005) and agomelatine (2009) were the first approved. Uses: Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. it helps to correct the circadian rhythm disorder often seen in patients who are visually impaired. Group: Pharmaceutical. CAS No. 609799-22-6. Pack Sizes: 100 mg. Product ID: B0084-072984. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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