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| Product | Description | |
|---|---|---|
| 3'-CPR II CPG | 3'-CPR II CPG, a vital tool in molecular biology, is renowned for unraveling the elusive role of Toll-like receptor 9 (TLR9) in shaping the immune system. In the domain of immunotherapy, the adjuvant supplements DNA vaccines and jumpstarts immune responses to eradicate cancer and infections. Dive into the intriguing world of 3'-CPR II CPG as its therapeutic potential has undergone rigorous scrutiny in pre-clinical and clinical trials. Group: Pharmaceutical. Alternative Names: 3'-CPR II CPG 1000; 3-(4,4'-Dimethoxytrityloxy)-2,2-(dicarboxymethylamido)propyl-1-O-succinoyl-long chain alkylamino-CPG; 3'-CPR II CPG 1000Å. Pack Sizes: 1 g. Product ID: B1370-376394. Custom synthesis is available. Send your inquiries for more information. |  London |
| A 841720 | A 841720 is a potent non-competitive mGlu1 receptor antagonist (IC50 = 10 nM) exhibiting 34-fold selectivity over mGluR5 and inactive to other mGluR receptors, neurotransmitter receptors, ion channels, and transporters. It inhibits complete Freund's adjuvant-induced inflammatory pain (ED50 = 23 μmol/kg) and decreases mechanical allodynia (ED50 = 28 μmol/kg) in mouse models. Group: Pharmaceutical. Alternative Names: A-841720; A 841720; A841720; 3-(azepan-1-yl)-9-(dimethylamino)pyrido[1,2]thieno[3,4-d]pyrimidin-4-one. CAS No. 869802-58-4. Pack Sizes: 1mg;1g;10g. Product ID: 869802-58-4. Molecular formula: C17H21N5OS. Mole weight: 343.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Benfotiamine | Benfotiamine is an amphiphilic S-acyl thiamine derivative used as a lipid soluble alternative source of bioavailable thiamine. Benfotiamine is being investigated in a variety of therapeutic applications. Uses: Adjuvants, immunologic. Group: Pharmaceutical. Alternative Names: Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl] ester; Benzoylthiamine monophosphate; Berdi; Betivina; Bietamine; Biotamin; Milgamma; Nitanevril; S-Benzoylthiamine O-monophosphate; Tabiomyl; Vitanevril; BTMP; Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl] ester; Benzoic acid, thio-, S-ester with N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide dihydrogen phosphate (ester); Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)-, S-benzoate O-(dihydrogen phosphate); 8088CB; Benfothiamine; Benzoylthiamine O-monophosphate; N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide S-benzoate O-phosphate; Neurostop; S-Benzoylthiamine monophosphate. CAS No. 22457-89-2. Pack Sizes: 500 g. Product ID: B1370-063311. Molecular formula: C19H23N4O6PS. Mole weight: 466.45. Custom synthesis is available. Send your inquiries for more information. | London |
| β-Glucan | β-Glucan is an extensively utilized natural polysaccharide within the biomedical sector,with immunomodulatory characteristics that augment immune system functionality and mitigate inflammation. This versatile compound finds application in studying an array of ailments such as cancer, allergies, viral infections and cardiovascular maladies. Uses: Adjuvants, immunologic. Group: Pharmaceutical. Alternative Names: (1,3)-β-Glucan; (1-3)-β-D-Glucan; (1→3)-β-D-Glucan; 1,3-β-d glucans; Aktival; Beta Right 101; Corapulan; Drieline; Epicor; Guardoran; Highcareen GS; Immunoglucan; ImmuStim; Macroforce; Maitake Gold; Now Glucan; NSC; Phellin; Poly(1→3)-β-D-glucan; Poly(1→3)-β-D-Glycopyranose; Polysaccharide 13140; PS 3; PS 3 (polysaccharide); Solgar; Sparan; SSG; Swanson; Sweet Beta Glucan; TAK; TAK (polysaccharide); TAK-N; Uniglucan 51; VitaStim; Wellmune; Wellmune WGP 3005; β-(1,3) glucans; β-1,3-D-Glucan; β-1,3-Glucan. CAS No. 9051-97-2. Pack Sizes: 10 g. Product ID: B1370-100340. Molecular formula: (C6H10O5)n. Custom synthesis is available. Send your inquiries for more information. | London |
| Calcium phosphate (3:2) | Calcium Phosphate can be used as an anti-caking agent, acidity regulator, nutritional supplement, flavoring agent, stabilizer and moisture retention agent. Calcium phosphate was used as an adjuvant in France in diphtheria, tetanus, pertussis, and poliomyelitis vaccines. Group: Pharmaceutical. Alternative Names: Phosphoric acid, calcium salt (2:3); Allogran-R; Bonarka; Calciresorb; Calcium orthophosphate (Ca3(PO4)2); Calcium phosphate; Calcium phosphate (Ca1.5(PO4)); Calcium phosphate (Ca10.5(PO4)7); Calcium tertiary phosphate; Cerasorb; Cerasorb Curasan; DET 10; EPSolute Instant S; JAX TCP; Mastergraft; Osferion; Phosphoric acid calcium(2+) salt (2:3); Posture; Synthograft; Tertiary calcium phosphate; Versacal MP; Vitoss; α-Tricalcium phosphate; β-TCP; β-Tricalcium phosphate; β-Whitlockite; Tricalcium phosphate. CAS No. 7758-87-4. Pack Sizes: 10 g. Product ID: B0001-308437. Molecular formula: Ca3O8P2. Mole weight: 310.18. Custom synthesis is available. Send your inquiries for more information. | London |
| Ceftiofur | Ceftiofur is produced by the strain of Semisynthetic third generation cephalosporin for injection. Its sodium salt is used in the animal preparations. It is resistant to antibiotic resistance enzyme beta-lactamase. It can be used for adjuvant treatment of bacterial diseases and viral diseases. It can also be used for postpartum health care of sows, to prevent and treat postpartum bacterial infections of sows, and to restore their bodies after delivery. Group: Pharmaceutical. Alternative Names: Excenel; Ceftiofurum; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-, (6R-(6alpha,7beta(Z)))-. CAS No. 80370-57-6. Pack Sizes: 1mg;1g;10g. Product ID: 80370-57-6. Molecular formula: C19H17N5O7S3. Mole weight: 523.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Chamigrenal | Chamigrenal, a pharmacological treatment of anxiety disorders, intricately works towards ameliorating the perturbed functioning of the GABA receptors that ensue due to the hyperactivity of the brain. The convoluted mechanism of action mediates a stupor gently and minimizes the manifestation of anxiety symptoms. Additionally, it occasionally serves as an adjuvant in the management of insomnia. Group: Pharmaceutical. Alternative Names: Spiro[5.5]?undec-2-ene-3-carboxaldehyde, 7,?7-dimethyl-11-methylene-, (-)?-. CAS No. 19912-84-6. Pack Sizes: 5 mg. Product ID: B0005-465632. Molecular formula: C15 H22 O. Mole weight: 218.33. Custom synthesis is available. Send your inquiries for more information. | London |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Deacetylated chitin; Poly(D-glucosamine); Poly-b-(1,4)-2-Amino-2-deoxy-D-glucose; 2-Amino-2-deoxy-(1,4)-b-D-glucopyranan; deacetylchitin; b-1,4-poly-D-glucosamine; poly-D-glucosamine; poly-(1,4-b-D-glucopyranosamine). CAS No. 9012-76-4. Pack Sizes: 1kg. Product ID: B1370-187887. Molecular formula: [C7H15NO4]n. Mole weight: 60-120 kDa. Custom synthesis is available. Send your inquiries for more information. | London |
| Cimetidine | Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors. Uses: Adjuvants, immunologic; analgesics, non-narcotic; anti-ulcer agents; enzyme inhibitors; histamine h2 antagonists. Group: Pharmaceutical. Alternative Names: SKF-92334; SKF 92334; SKF92334. CAS No. 51481-61-9. Pack Sizes: 50 g. Product ID: B2692-334512. Molecular formula: C10H16N6S. Mole weight: 252.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Ginsenoside Rh4 | Ginsenoside Rh4 is a saponin isolated from the roots of Panax notoginseng (Burk.) F. H. Chen. Ginsenoside Rh4 inhibits Wnt/β-Catenin, JAK2/STAT3, TGF-β/Smad2/3 and other signaling pathways. It is used as an adjuvant with low or non-haemolytic effect. Uses: Antitumour. Group: Pharmaceutical. Alternative Names: Ginsenoside Rh(4). CAS No. 174721-08-5. Pack Sizes: 5 mg. Product ID: B1370-003067. Molecular formula: C36H60O8. Mole weight: 620.87. Custom synthesis is available. Send your inquiries for more information. | London |
| Glycopyrrolate Bromide | Glycopyrrolate bromide is a muscarinic competitive antagonist used as an antispasmodic. Uses: Adjuvants, anesthesia. Group: Pharmaceutical. Alternative Names: 3-[(2-Cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidinium Bromide; 3-Hydroxy-1,1-dimethylpyrrolidinium Bromide α-Cyclopentylmandelate; AHR-504; Asecryl; Copyrrolate; Gastrodyn; NSC 250836; NVA 237; Nodapton; Robanul; Robinul; Tarodyl; Tarodyn; Glycopyrrolate; GLYCOPYRROLATE; Glycopyrronium bromide; Gastrodyn; NVA-237; NVA237. CAS No. 596-51-0. Pack Sizes: 1 g. Product ID: B0084-072614. Molecular formula: C19H28BrNO3. Mole weight: 398.33. Custom synthesis is available. Send your inquiries for more information. | London |
| Hyoscyamine hemisulfate | Hyoscyamine sulphate is a sulphate salt form of 3(S)-endo atropine isomer. Hyoscyamine is a non-selective antagonist of muscarinic receptors that inhbits the parasympathetic activities of acetylcholine. It is used for the treatment of stomach/intestinal problems, as well as bladder and bowel control problems, and Parkinson's disease. Uses: Adjuvants, anesthesia. Group: Pharmaceutical. Alternative Names: Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-, sulfate (2:1); 1αH,5αH-Tropan-3α-ol, (-)-tropate (ester), sulfate (2:1) (salt); Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-, sulfate (2:1) (salt; Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-, sulfate (2:1) (salt); Egazil; Hyoscyamine sulfate; Hyoscyamine sulfate (2:1); Hyoscyamine sulfate (2:1) (salt); Levsin; Levsin sulfate; Levsinex; NuLev. CAS No. 620-61-1. Pack Sizes: 1mg;1g;10g. Product ID: NP0030. Molecular formula: C17H23NO3.1/2H2O4S. Mole weight: 676.82. Custom synthesis is available. Send your inquiries for more information. | London |
| KIN1148 | KIN1148, a small-molecule IRF3 agonist, associates with and activates recombinant RIG-I protein in cell-free assays. KIN1148 is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. Group: Pharmaceutical. Alternative Names: KIN-1148; KIN 1148; KIN1148; N-([1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)naphthalene-2-carboxamide. CAS No. 1428729-56-9. Pack Sizes: 100 mg. Product ID: B0084-007650. Molecular formula: C19H11N3OS2. Mole weight: 361.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Meldonium dihydrate | Mildronate is a potent γ-butyrobetaine hydroxylase inhibitor, with a half maximal inhibitory concentration (IC50) value of 62 μM. Uses: Adjuvants, immunologic. Group: Pharmaceutical. Alternative Names: Mildronate dihydrate; Mildronate (dihydrate); 3-(2,2,2-Trimethylhydrazinium)propionate dihydrate; 1,1,1-Trimethyl-2-(2-carboxyethyl)hydrazine zwitterion dihydrate. CAS No. 86426-17-7. Pack Sizes: 500 mg. Product ID: B0084-099416. Molecular formula: C6H18N2O4. Mole weight: 182.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Poly(D,L-lactide-co-glycolide) | Poly(D,L-lactide-co-glycolide) is used for macromolecular therapeutic delivery. Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid can enhance the level of toxin-neutralizing antibodies. Group: Pharmaceutical. Alternative Names: Purasorb(R) PDLG; Poly(D,L-lactide-co-glycolide); Poly(DL-lactide-co-glycolide) (50:50); Poly(DL-lactide-co-glycolide) (85:15); Poly(DL-lactide/glycolide); DL-lactide/glycolide copolymer; LACTEL BP-0100; LACTEL BP-0200. CAS No. 26780-50-7. Pack Sizes: 10 g. Product ID: B2697-011136. Molecular formula: (C3H4O2)x(C2H2O2)y. Custom synthesis is available. Send your inquiries for more information. | London |
| Ponesimod | Ponesimod is an orally active and selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator that acts as a functional antagonist. It has potential immunomodulating activity. It may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. It is also an experimental drug for the treatment of multiple sclerosis (MS) and psoriasis. It protects against lymphocyte-mediated tissue inflammation. It activated S1P(1)-mediated signal transduction with high potency (EC(50) of 5.7 nM) and selectivity in vitro. It prevented edema formation, inflammatory cell accumulation and cytokine release in the skin of mice with delayed-type hypersensitivity. It also prevented the increase in paw volume and joint inflammation in rats with adjuvant-induced arthritis. It reduces both the amount of circulating peripheral lymphocytes and the infiltration of lymphocytes into target tissues by preventing egress of lymphocytes. It was developed by Actelion. It is in Clinical stage three. Uses: Ponesimod acts as a functional antagonist. it has potential immunomodulating activity. it may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. it is also an experimental drug for the treatment of multiple sclerosis (ms) and psoriasis. Group: Pharmaceutical. Alternative Names: ACT-128800; ACT 128800; ACT128800; Ponvory; (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolyl | London |
| QS-21 | QS-21 is a natural triterpenoid saponin extracted from the soap bark tree. It has the potential use as an immunologic adjuvant in vaccine to enhance their efficacy. Group: Pharmaceutical. Alternative Names: Saponin QA 21V1; QS-21. CAS No. 141256-04-4. Pack Sizes: 1 mg. Product ID: B0005-279950. Molecular formula: C92H148O46. Mole weight: 1990.13. Custom synthesis is available. Send your inquiries for more information. | London |
| Tariquidar | Tariquidar, also known as XR9576, is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Group: Pharmaceutical. Alternative Names: XR 9576; XR9576; XR-9576; D06008. CAS No. 206873-63-4. Pack Sizes: 50 mg. Product ID: B0084-087193. Molecular formula: C38H38N4O6. Mole weight: 646.744. Custom synthesis is available. Send your inquiries for more information. | London |
| Thymalfasin | Thymalfasin is an immunomodulating agent indicated as an adjuvant for influenza vaccine in elderly patients. Group: Pharmaceutical. Alternative Names: Thymosin α1. CAS No. 69440-99-9. Pack Sizes: 5 mg. Product ID: BAT-010336. Molecular formula: C129H215N33O55. Mole weight: 3108.31. Custom synthesis is available. Send your inquiries for more information. | London |
| Tomatine | Tomatine is a glycoalkaloid extracted from the fruits of Solanum lycopersicum. Group: Pharmaceutical. Alternative Names: Lycopersicin; (3β,5α,22β,25S)-Spirosolan-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside; α-Tomatine; NSC 234440; NSC 9223; TiterMax tomatine; Tomatine vaccine adjuvant. CAS No. 17406-45-0. Pack Sizes: 20 mg. Product ID: NP0027. Molecular formula: C50H83NO21. Mole weight: 1034.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Trehalose-6,6'-dibehenate | Trehalose-6,6'-dibehenate is a bioactive glycolipid and an analog of mycobacterial cord factor. Trehalose-6,6'-dibehenate is considered less toxic and an efficient vaccine adjuvant for tuberculosis. Group: Pharmaceutical. Alternative Names: 22:0 Trehalose; D-(+)-trehalose 6,6'-dibehenate; 6,6'-didocosanoyl-α,α'-trehalose; TDB; α-D-Glucopyranoside, 6-O-(1-oxodocosyl)-α-D-glucopyranosyl, 6-docosanoate. CAS No. 66758-35-8. Pack Sizes: 25 mg. Product ID: B1370-252651. Molecular formula: C56H106O13. Mole weight: 987.43. Custom synthesis is available. Send your inquiries for more information. | London |
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