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| Product | Description | |
|---|---|---|
| S-(5'-Adenosyl)-L-methionine chloride dihydrochloride | S-(5'-Adenosyl)-L-methionine chloride dihydrochloride, widely recognized as a pivotal constituent within the biomedical industry due to its remarkable therapeutic characteristics, manifests an extensive repertoire of applications encompassing the treatment of liver ailments, including cirrhosis and hepatitis, as well as the remediation of depressive disorders and osteoarthritis. Its profound efficacy in delivering meticulous relief tailored to specific ailments is instrumental in fostering an overarching state of holistic wellness. Group: Pharmaceutical. Alternative Names: SAM chloride dihydrochloride; Active methionine; AdoMet. CAS No. 86867-01-8. Pack Sizes: 100 mg. Product ID: B1370-337866. Molecular formula: C15H25Cl3N6O5S. Mole weight: 507.82. Custom synthesis is available. Send your inquiries for more information. |  London |
| S-(5'-Adenosyl)-L-methionine iodide | 5mg Pack Size. Group: Amino Acids, Biochemicals, Building Blocks, Organics. Formula: C15H23IN6O5S. CAS No. 3493-13-8. Prepack ID : 52277849-5mg. Molecular Weight : 526.35. |  |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A is an inhibitor of S-adenosylmethionine-dependent methyltransferase. In combination with sodium butyrate, 3-Deazaneplanocin A can induce epigenetically reprogramming of human embryonic stem cells (hESC). Group: Pharmaceutical. Alternative Names: DZNep; (1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol. CAS No. 102052-95-9. Pack Sizes: 10 mg. Product ID: B0084-462897. Molecular formula: C12H14N4O3. Mole weight: 262.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Ademethionine Disulfate Tosylate | Ademetionine Disulfate Tosylate is used to study the survival time in various damage brain models. Group: Pharmaceutical. Alternative Names: 4-Methylbenzenesulfonate (salt) Sulfate (salt) (1:1:1:1) (9CI); FO 1561; S-Adenosyl-L-methionine Disulfate Tosylate; 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine Sulfate 4-Methylbenzenesulfonate Sulfate; (3S)-5'-[(3-Amino-3-carboxyp. CAS No. 97540-22-2. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008061. Molecular formula: C22H34N6O16S4. Mole weight: 766.8. Custom synthesis is available. Send your inquiries for more information. | London |
| AMI-1 | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Group: Pharmaceutical. Alternative Names: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. CAS No. 20324-87-2. Pack Sizes: 50 mg. Product ID: B2693-087022. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. Custom synthesis is available. Send your inquiries for | London |
| GSK126 | GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity. GSK126 decreases global H3K27me3 levels and reactivates silenced PRC2 target genes. GSK126 effectively inhibits the proliferation of EZH2 mutant DLBCL cell lines and markedly inhibits the growth of EZH2 mutant DLBCL xenografts in mice. Together, these data demonstrate that pharmacological inhibition of EZH2 activity may provide a promising treatment for EZH2 mutant lymphoma. Group: Pharmaceutical. Alternative Names: GSK2816126; GSK-2816126; GSK 2816126; GSK-126; GSK 126; (S)-1-(sec-Butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide. CAS No. 1346574-57-9. Pack Sizes: 100 mg. Product ID: B1370-107617. Molecular formula: C31H38N6O2. Mole weight: 526.69. Custom synthesis is available. Send your inquiries for more information. | London |
| Homocysteine Methyltransferase, Recombinant | Homocysteine Methyltransferase, Recombinant is a key enzyme in new biocatalyst technology. Group: Pharmaceutical. Alternative Names: Homocysteine S-methyltransferase; S-adenosylmethionine homocysteine transmethylase. CAS No. 9012-40-2. Pack Sizes: 10 mg. Product ID: B1370-099183. Custom synthesis is available. Send your inquiries for more information. | London |
| Methylcobalamin | Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine. Group: Pharmaceutical. Alternative Names: Cobinamide, Co-methyl-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3); Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole; Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D. CAS No. 13422-55-4. Pack Sizes: 1mg;1g;10g. Product ID: NP3442. Molecular formula: C63H91CoN13O14P. Mole weight: 1344.38. Custom synthesis is available. Send your inquiries for more information. | London |
| MTDIA | MTDIA is a human 5'-methylthioadenosine phosphorylase (MTAP) inhibitor, which is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. It is used as an anticancer candidate. Group: Pharmaceutical. Alternative Names: Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium. CAS No. 653592-04-2. Pack Sizes: 100 mg. Product ID: B2693-476086. Molecular formula: C13H19N5OS. Mole weight: 294.35. Custom synthesis is available. Send your inquiries for more information. | London |
| MTDIA hydrochloride | MTDIA is a methylthioadenosine phosphorylase (MTAP) inhibitor. MTAP is responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer drug candidates and MTDIA is one of these TS analogues. Uses: Anticancer drug candidate. Group: Pharmaceutical. Alternative Names: (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium chloride; MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl. CAS No. 1399840-35-7. Pack Sizes: 50 mg. Product ID: B0084-475405. Molecular formula: C13H20ClN5OS. Mole weight: 329.85. Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine | (S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine, an important compound, is frequently utilized in scientific endeavors towards the development of medications for the treatment of diverse ailments, encompassing cancer and autoimmune diseases. Typically employed as a substrate for enzymes participating in the purine metabolic pathway, this substance exhibits notably high perplexity, owing to its intricate chemical composition. In addition, it boasts considerable burstiness, with some instances of relatively lucid nomenclature alongside more elaborative descriptions of its molecular properties. Uses: A novel biomarker for predicting susceptibility of a subject to a mental or neurodegenerative disorder. Group: Pharmaceutical. Alternative Names: S-adenosylhomocysteine; S-adenosyl-L-homocysteine; SAH; S-(5'-adenosyl)-L-homocysteine; AdoHcy. CAS No. 979-92-0. Pack Sizes: 100 mg. Product ID: B0001-080350. Molecular formula: C14H20N6O5S. Mole weight: 384.41. Custom synthesis is available. Send your inquiries for more information. | London |
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