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Terpendole I Quick enquiry Where to buy Suppliers range | Terpendole I is a fungal metabolite originally isolated from A. yamanashiensis. It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50=145 μM) and is active against the bacteria B. cereus and B. subtilis (MICs = 100 μg/ml for both) but not S. aureus, P. aeruginosa, or K. pneumoniae (MICs = >200 μg/ml for all) or the fungus C. albicans (MIC = 200 μg/ml). It is also cytotoxic to HeLa cells with an IC50 value of 52.6 μM. Group: Pharmaceuticals. Alternative Names: Terpendole I; 167612-17-1; (1S, 2R, 5S, 7S, 8R, 9R, 11S, 12S, 15S)-7-(2-hydroxypropan-2-yl)-1, 2-dimethyl-6, 10-dioxa-24-azaheptacyclo[13.10.0.02, 12.05, 11.09, 11.017, 25.018, 23]pentacosa-17(25), 18, 20, 22-tetraene-8, 12-diol; (2S, 3R, 3aR, 4aS, 4bS, 6aS, 12bS, 12cR, 14aS)-3, 3a, 5, 6, 6a, 7, 12, 12b, 12c, 13, 14, 14a-dodecahydro-2-(1-hydroxy-1-methylethyl)-12b, 12c-dimethyl-2H, 4bH-oxireno[4', 4'a]-1-benzopyrano[5', 6':6, 7]indeno[1, 2-b]indole-3, 4b-diol; SCHEMBL20869892. CAS No. 167612-17-1. Pack Sizes: 1mg; 1g; 10g. Product ID: 167612-17-1. Custom synthesis is available. Send your inquiries for more information. | London |