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| Product | Description | |
|---|---|---|
| Acivicin | Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research. Uses: Protease inhibitor. Group: Pharmaceutical. CAS No. 42228-92-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-00541. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Bevirimat | Bevirimat, also known as MPC-4326 and PA-457, is an anti-HIV drug derived from a betulinic acid-like compound, first isolated from Syzygium claviflorum, a Chinese herb. It is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition. Like protease inhibitors, bevirimat and other maturation inhibitors interfere with protease processing of newly translated HIV polyprotein precursor, called gag. Bevirimat prevents this viral replication by specifically inhibiting cleavage of the capsid protein (CA) from the SP1 spacer protein. Group: Pharmaceutical. CAS No. 174022-42-5. Pack Sizes: 5 mg. Product ID: B0084-244897. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pepstatin A | Pepstatin A is a potent aspartic protease inhibitor, and also inhibits HIV replication.It is a hexa-peptide containing the unusual amino acid statine (Sta, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid), having the sequence Isovaleryl-Val-Val-Sta-Ala-Sta (Iva-Val-Val-Sta-Ala-Sta). Uses: Protease inhibitors. Group: Pharmaceutical. CAS No. 26305-03-3. Pack Sizes: 500 mg. Product ID: BAT-010775. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PF 429242 dihydrochloride | PF 429242 is a reversible and competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM), a transcriptional regulators of cholesterol, fatty acid, and glucose metabolism. It reduces hepatic synthesis of cholesterol and fatty acid in mice. Group: Pharmaceutical. CAS No. 2248666-66-0. Pack Sizes: 100 mg. Product ID: B1370-291470. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pseudolaric acid B | Pseudolaric acid B (PAB), which comes from the bark of Pseudolarix kaempferi Gordon, has diverse effects that are relevant to cancer therapy, including apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo. pseudolaric acid B can trigger apoptosis by decreasing Bcl-2 levels and activating caspase-3 protease. The future development of PAB as a cancer therapeutic is ongoing. Besides, PAB significantly suppressed proliferation of DU145 cells in a dose-dependent manner without obvious cytotoxicity. PAB may inhibit growth of HRPC DU145 cells and induce apoptosis through ROS generation and Bcl-2 degradation via the activation of the ubiquitin-proteasome pathway. Uses: Antifungal/antifertility. Group: Pharmaceutical. CAS No. 82508-31-4. Pack Sizes: 10 mg. Product ID: NP1536. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tumulosic acid | Tumulosic acid is a triterpenoid found in Daedalea dickinsii and Wolfiporia cocos. It inhibits KLK5 protease activity with IC50 of 14.84 μM. Group: Pharmaceutical. CAS No. 508-24-7. Pack Sizes: 10 mg. Product ID: B2703-379034. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ulinastatin | Ulinastatin is an acid-resistant protease inhibitor derived from human urine, acting as a potent anti-inflammatory agent. It was shown to inhibit the activities of a variety of enzymes, including trypsin, chymotrypsin, thrombin, kallikrein, plasmin, elastase, cathepsin, lipase, hyaluronidase, factors IXa, Xa, XIa, and XlIa, and polymorphonuclear leukocyte elastase. Group: Pharmaceutical. CAS No. 80449-31-6. Pack Sizes: 1 g. Product ID: B2693-135299. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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