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Donepezil impurity. Uses: 4-[(2,3-dihydro-5,6-dimethoxy-1-oxo-1h-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium is an isotope labelled impurity in the synthesis of donepezil (d531750), an inhibitor of acetylcholinesterase. Group: Pharmaceutical. Alternative Names: 2-[[1,1-bis(phenylmethyl)-4-piperidin-1-iumyl]methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;bromide; 2-[(1,1-dibenzylpiperidin-1-ium-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;bromide. CAS No. 844694-85-5. Pack Sizes: 100 mg. Product ID: B0794-470368. Molecular formula: C31H36BrNO3. Mole weight: 550.53. Custom synthesis is available. Send your inquiries for more information.
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1-Methyl-4-piperidone-[2,2,6,6-d4]
1-Methyl-4-piperidone-[2,2,6,6-d4], a deuterium-labeled analog of the potent neurotransmitter acetylcholine, has been extensively employed to scrutinize the intricate metabolic pathways of acetylcholine. Owing to its properties, it has garnered immense interest in the pharmaceutical and agrochemical sectors, rendering it a vital precursor in various chemical syntheses. The intricate isotopic labeling of this compound confers significant benefits in terms of stability, efficiency, and sensitivity in investigative studies. Group: Pharmaceutical. Alternative Names: N-Methyl-4-piperidone-d4; 1-Methyl-4-oxopiperidine-d4. CAS No. 1189723-14-5. Pack Sizes: 10 mg. Product ID: BLP-009661. Molecular formula: C6H7D4NO. Mole weight: 117.18. Custom synthesis is available. Send your inquiries for more information.
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1-Methylpyridin-1-ium-2-carboxamide
1-Methylpyridin-1-ium-2-carboxamide is an impurity of Pralidoxime Chloride, a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. Alternative Names: 1-Methyl-2-carbamoylpyridinium; 1-methylpyridine-2-carboxamide; 2-Carbamoyl-1-methyl-pyridinium. CAS No. 45750-74-1. Pack Sizes: 100 mg. Product ID: B0157-284893. Molecular formula: C7H9ClN2O. Mole weight: 172.61. Custom synthesis is available. Send your inquiries for more information.
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1-methylpyridin-1-ium-2-carboxamide chloride
An impurity of Pralidoxime Chloride. Pralidoxime Chloride is a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. Alternative Names: 21032-31-5; 2-Carbamoyl-1-methylpyridin-1-ium chloridePyridinium, 2-(aminocarbonyl)-1-methyl-, chloride (1:1); SCHEMBL8434012; DTXSID70545796. CAS No. 21032-31-5. Pack Sizes: 5 mg. Product ID: B2694-338837. Molecular formula: C7H9ClN2O. Mole weight: 172.61. Custom synthesis is available. Send your inquiries for more information.
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1-methylpyridin-1-ium-2-carboxamide iodide
An impurity of Pralidoxime Chloride. Pralidoxime Chloride is a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. Alternative Names: 2-Carbamoyl-1-methylpyridinium iodide; 3861-69-6; 2-(AMINOCARBONYL)-1-METHYLPYRIDINIUM IODIDE; PCMM; 2-CARBAMOYL-1-METHYLPYRIDIN-1-IUM IODIDE; Iodide 2-(aminocarbonyl)-1-methylpyridinium; Pyridinium, 2-(aminocarbonyl)-1-methyl-, iodide; Pyridinium, 2-carbamoyl-1-methyl-, iodide; 1-methylpyridin-1-ium-2-carboxamide; iodide. CAS No. 3861-69-6. Pack Sizes: 5 mg. Product ID: B2694-338836. Molecular formula: C7H9IN2O. Mole weight: 264.06. Custom synthesis is available. Send your inquiries for more information.
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1-methylpyridin-1-ium-2-carboxylic acid
1-methylpyridin-1-ium-2-carboxylic acid is an impurity of Pralidoxime Chloride, a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. Alternative Names: Homarine Hydrochloride. CAS No. 3697-38-9. Pack Sizes: 100 mg. Product ID: B0157-131635. Molecular formula: C7H8ClNO2. Mole weight: 173.596. Custom synthesis is available. Send your inquiries for more information.
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3-Hydroxy Donepezil
3-Hydroxy Donepezil is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Group: Pharmaceutical. Alternative Names: 2-((1-Benzylpiperidin-4-yl)methyl)-3-hydroxy-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one. CAS No. 2097683-67-3. Pack Sizes: 50 mg. Product ID: B1370-342805. Molecular formula: C24H29NO4. Mole weight: 395.5. Custom synthesis is available. Send your inquiries for more information.
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7,14-Epoxymeliatoxin A1
Toxicological properties of 7,14-Epoxymeliatoxin A1, a coral-derived toxin, have been extensively researched. This potent inhibitor of nicotinic acetylcholine receptors holds potential for neurological studies on afflictions including Alzheimer's and Parkinson's. Its notable selectivity and distinct inhibition mechanism have garnered significant scientific attention for unveiling new therapeutic strategies towards disorders of the brain. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B0005-482207. Custom synthesis is available. Send your inquiries for more information.
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A-366833
A-366833 is a an agonist at neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Uses: Neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Group: Pharmaceutical. Alternative Names: A-366833; A 366833; A366833; 5-[(1R,5S)-3,6-diazabicyclo[3.2.0]heptan-6-yl]pyridine-3-carbonitrile. CAS No. 370882-41-0. Pack Sizes: 1mg;1g;10g. Product ID: 370882-41-0. Molecular formula: C11H12N4. Mole weight: 200.24. Custom synthesis is available. Send your inquiries for more information.
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A 844606
A 844606 is a selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist (EC50 = 1.4 and 2.2 μM at human and rat receptors, respectively). It has no measurable effect on α4β2 nAChRs. Group: Pharmaceutical. Alternative Names: A 844606; A844606; A-844606; 2-(Hexahydro-5-methylpyrrolo[3,4-c]pyrrol-2(1H)-yl)-9H-xanthen-9-one. CAS No. 861119-08-6. Pack Sizes: 1mg;1g;10g. Product ID: 861119-08-6. Molecular formula: C20H20N2O2. Mole weight: 320.38. Custom synthesis is available. Send your inquiries for more information.
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Abeprazan
Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is used for the treatment of 5-HT receptor or muscarinic acetylcholine receptor-mediated diseases. Group: Pharmaceutical. Alternative Names: Fexuprazan; 5-(2,4-Difluorophenyl)-1-[(3-fluorophenyl)sulfonyl]-4-methoxy-N-methyl-1H-pyrrole-3-methanamine; DWP14012; DWP-14012. CAS No. 1902954-60-2. Pack Sizes: 1mg;1g;10g. Product ID: 1902954-60-2. Molecular formula: C19H17F3N2O3S. Mole weight: 410.41. Custom synthesis is available. Send your inquiries for more information.
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Abeprazan hydrochloride
Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is used for the treatment of 5-HT receptor or muscarinic acetylcholine receptor-mediated diseases. Group: Pharmaceutical. Alternative Names: DWP14012 hydrochloride; Fexuprazan hydrochloride. CAS No. 1902954-87-3. Pack Sizes: 1mg;1g;10g. Product ID: 1902954-87-3. Molecular formula: C19H18ClF3N2O3S. Mole weight: 446.87. Custom synthesis is available. Send your inquiries for more information.
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ABT 089 dihydrochloride
ABT 089 dihydrochloride is a selective α4β2 nicotinic acetylcholine receptor partial agonist (Ki = 16 nM) with >1000-fold and >10,000-fold selectivity for α4β2 over α1β1γ1 and α7 receptors, respectively. ABT 089 dihydrochloride is used as a nootropic and neuroprotective agent. Uses: Nootropic and neuroprotective agent. Group: Pharmaceutical. Alternative Names: ABT 089 dihydrochloride; ABT089 dihydrochloride; ABT-089 dihydrochloride; 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride; Pozanicline hydrochloride. CAS No. 161416-61-1. Pack Sizes: 1mg;1g;10g. Product ID: 161416-61-1. Molecular formula: C11H16N2O.2HCl. Mole weight: 265.18. Custom synthesis is available. Send your inquiries for more information.
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ABT-20
ABT-202, a small molecule, asts as an agonist at neural nicotinic acetylcholine receptors. Uses: An agonist at neural nicotinic acetylcholine receptors and has been researched for use as an analgesic. Group: Pharmaceutical. Alternative Names: ABT-202; ABT 202; ABT202; (3R)-1-(Pyridin-3-yl)pyrrolidin-3-amine. CAS No. 309959-34-0. Pack Sizes: 1mg;1g;10g. Product ID: 309959-34-0. Molecular formula: C9H13N3. Mole weight: 163.22. Custom synthesis is available. Send your inquiries for more information.
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ABT-418 hydrochloride
ABT-418 is a neuronal nicotinic acetylcholine receptor agonist with anxiolytic and cognition enhancing activities. Group: Pharmaceutical. Alternative Names: ABT-418 HCl; (S)-3-Methyl-5-(1-methylpyrrolidin-2-yl)-isoxazole HCl. CAS No. 147388-83-8. Pack Sizes: 1mg;1g;10g. Product ID: 147388-83-8. Molecular formula: C9H15ClN2O. Mole weight: 202.68. Custom synthesis is available. Send your inquiries for more information.
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Acotiamide
Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Group: Pharmaceutical. Alternative Names: Acotiamide;MZ-338;UNII-D42OWK5383. CAS No. 185106-16-5. Pack Sizes: 100 mg. Product ID: B0084-284892. Molecular formula: C21H30N4O5S. Mole weight: 450.554. Custom synthesis is available. Send your inquiries for more information.
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Benzetimide hydrochloride
Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist that has anticholinergic properties and could block pilocarpine-induced lacrimation. Uses: Amuscarinic acetylcholine receptor antagonist. Group: Pharmaceutical. Alternative Names: R 4929; R4929; R-4929Spasmentral;3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione;hydrochloride. CAS No. 5633-14-7. Pack Sizes: 500 mg. Product ID: B0084-125722. Molecular formula: C23H26N2O2.HCl. Mole weight: 398.93. Custom synthesis is available. Send your inquiries for more information.
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beta-Amyrenone
β-Amyrone isolated from the leaves of Cyclocarya paliums. It has snakevenom inactivating action. Uses: Anti-acetylcholinesterase (ache) activity. Group: Pharmaceutical. Alternative Names: (6aR,6bS,8aR,12aS,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-2,4a,5,6,7,8,9,10,12,12a,14,14a-dodecahydro-1H-picen-3-one. CAS No. 638-97-1. Pack Sizes: 1mg;1g;10g. Product ID: NP6313. Molecular formula: C30H48O. Mole weight: 424.7. Custom synthesis is available. Send your inquiries for more information.
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β-Eudesmol
β-Eudesmol is a sesquiterpene found in a wide range of plants, including Cannabis, and has diverse biological activities. It acts as a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs). Group: Pharmaceutical. Alternative Names: (+)-β-Eudesmol; beta-Eudesmol. CAS No. 473-15-4. Pack Sizes: 10 mg. Product ID: B2703-015067. Molecular formula: C15H26O. Mole weight: 222.37. Custom synthesis is available. Send your inquiries for more information.
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COG 133
COG 1333 is a fragment of ApoE that exhibits anti-inflammatory and neuroprotective effects and could also be an antagonist at α7 nicotinic acetylcholine receptors. Group: Pharmaceutical. Alternative Names: COG133; COG-133; Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu. CAS No. 514200-66-9. Pack Sizes: 5 mg. Product ID: BAT-006089. Molecular formula: C97H181N37O19. Mole weight: 2169.73. Custom synthesis is available. Send your inquiries for more information.
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Corynoline
Corynoline, which is found in the tubers of Corydalis ambigua, is an acetylcholinesterase inhibitor. Uses: Sedative/anti-leptospira. Group: Pharmaceutical. Alternative Names: Corynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-, dimethyl-, (5bR,6S,12bR)-; (5bR)-5bα,13-Dimethyl-5bα,6,7,12bα,13,14-hexahydro[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-6β-ol; 13-Methylchelidonan-11β-ol. CAS No. 18797-79-0. Pack Sizes: 25 mg. Product ID: NP0588. Molecular formula: C21H21NO5. Mole weight: 367.4. Custom synthesis is available. Send your inquiries for more information.
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Corynoxidine
Corynoxidine is an antibacterial alkaloid isolated from the roots of Stephania epigaea. Corynoxidine also acts as a dose-dependent acetylcholinesterase inhibitor. Group: Pharmaceutical. Alternative Names: Tetrahydropalmatine N-oxide; (7S,13aS)-2,3,9,10-tetramethoxy-7-oxido-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium. CAS No. 57906-85-1. Pack Sizes: 1 mg. Product ID: NP0804. Molecular formula: C21H25NO5. Mole weight: 371.433. Custom synthesis is available. Send your inquiries for more information.
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Cytisine
Cytisine is a nicotinic acetylcholine receptor (nAChR) agonist. It has been used medically to help with smoking cessation. Cytisine can be used in health products. Uses: Smoking cessation. Group: Pharmaceutical. Alternative Names: Baptitoxin; Citizin; HSDB 3560; HSDB3560; HSDB-3560; Laburnin; NSC 407282; NSC407282; NSC-407282; Sophorin; Cytisine; Cytisinicline; Baptitoxine; Sophorine; (-)-Cytisine; Laburnin. CAS No. 485-35-8. Pack Sizes: 5 g. Product ID: NP0545. Molecular formula: C11H14N2O. Mole weight: 190.246. Custom synthesis is available. Send your inquiries for more information.
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[D-Ala2]-Leucine enkephalin
[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors. It inhibits the release of acetylcholine and inhibits muscle contraction. Group: Pharmaceutical. Alternative Names: L-Leucine, N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-; L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-L-leucine; 1-5-(D-Ala2)-dynorphin; 2-D-Alanine-5-leucine-enkephalin; [D-Ala2]leucine-enkephalin; H-Tyr-D-Ala-Gly-Phe-Leu-OH; Leuphasyl; NSC 374895; Pentapeptide 18; Tyr-D-Ala-Gly-Phe-Leu; Tyr-D-Ala-Gly-Phe-Leu-OH; Tyrosyl-D-alanylglycylphenylalanylleucine. CAS No. 64963-01-5. Pack Sizes: 1 g. Product ID: BAT-010076. Molecular formula: C29H39N5O7. Mole weight: 569.65. Custom synthesis is available. Send your inquiries for more information.
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Demecarium bromide
Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals. Uses: Cholinesterase inhibitors; miotics. Group: Pharmaceutical. Alternative Names: 3,3'-[1,10-decanediylbis[(methylimino)carbonyloxy]]bis[N,N,N-trimethylbenzenaminium Bromide; (m-Hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; (m-hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; Demekarium Bromide; Demekastigmine Bromide; Frumtosnil; Humorsol. CAS No. 56-94-0. Pack Sizes: 500 mg. Product ID: B0084-071868. Molecular formula: White Solid. Mole weight: 716.59. Custom synthesis is available. Send your inquiries for more information.
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Dicyclomine-[d4] Hydrochloride
Dicyclomine-[d4] Hydrochloride is a deuterium labelled form of Dicyclomine. Dicyclomine is a medication that is used to treat spasms of the intestines such as occur in irritable bowel syndrome. Dicyclomine is an M1 and M2 muscarinic acetylcholine receptor antagonist. Group: Pharmaceutical. Alternative Names: Dicyclomine-d4 Hydrochloride. Pack Sizes: 10 mg. Product ID: BLP-005108. Molecular formula: C19H32D4ClNO2. Mole weight: 349.97. Custom synthesis is available. Send your inquiries for more information.
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Diethylethanolamine Dicyclohexylketone
Diethylethanolamine Dicyclohexylketone is an impurity of Dicyclomine, which is an M1 and M2 muscarinic acetylcholine receptor antagonist. Group: Pharmaceutical. CAS No. 2731926-17-1. Pack Sizes: 100 mg. Product ID: B1370-286446. Molecular formula: C19H35NO2. Mole weight: 309.49. Custom synthesis is available. Send your inquiries for more information.
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Dipeptide diaminobutyroyl benzylamide diacetate
Dipeptide diaminobutyroyl benzylamide is a biomimetic peptide and a muscarinic acetylcholine receptor antagonist. It mimics the action of the temple viper venom peptide Waglerin-1 to block sodium uptake and induce muscle relaxation. A cosmetic formulation acts as an anti-wrinkle ingredient used in anti-aging products. Group: Pharmaceutical. Alternative Names: H-β-Ala-Pro-Dab-NH-benzyl acetate; H-β-Ala-Pro-DabNHBz acetate; Syn-Ake acetate; Snake trippetide acetate; (2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate; BCP18324; Butanamide, β-alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)-, (2S)-, acetate (1:2); Butanamide, β-alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)-, (2S)-, diacetate; Dipeptide diaminobutyryl benzylamide diacetate; SYN-AKE. CAS No. 823202-99-9. Pack Sizes: 1 g. Product ID: BAT-010789. Molecular formula: C19H29N5O3.2C2H4O2. Mole weight: 495.57. Custom synthesis is available. Send your inquiries for more information.
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Donepezil
Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Group: Pharmaceutical. Alternative Names: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE. CAS No. 120014-06-4. Pack Sizes: 50 g. Product ID: B2692-082304. Molecular formula: C24H29NO3. Mole weight: 379.49. Custom synthesis is available. Send your inquiries for more information.
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Etiracetam
Etiracetam is an acetylcholine agonist used as a nootropic drug of the racetam family. S-enantiomer, Levetiracetam, is more active compared to the opposite R-enantiomer, UCB L-060. Uses: Nootropic drug. Group: Pharmaceutical. Alternative Names: UCB 6474; UCB6474; UCB-6474; 2-(2-oxopyrrolidin-1-yl)butanamide. CAS No. 33996-58-6. Pack Sizes: 5 g. Product ID: B2693-066496. Molecular formula: C8H14N2O2. Mole weight: 170.21. Custom synthesis is available. Send your inquiries for more information.
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Flutropium bromide
Flutropium bromide, a potent long-acting muscarinic antagonist, is utilized for the management of chronic obstructive pulmonary disease (COPD) to enhance pulmonary function and alleviate exacerbations. This mechanism involves the inhibition of acetylcholine's effect on muscarinic receptors within the airways, resulting in bronchodilation. Group: Pharmaceutical. CAS No. 63516-07-4. Pack Sizes: 1mg;1g;10g. Product ID: 63516-07-4. Molecular formula: C24H29BrFNO3. Mole weight: 478.39. Custom synthesis is available. Send your inquiries for more information.
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Galantamine hydrobromide
Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. Uses: Nootropic agents. Group: Pharmaceutical. Alternative Names: 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-; 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, monohydrobromide, (4aS,6R,8aS)-; Galanthamine, hydrobromide; (-)-Galantamine hydrobromide; (-)-Galanthamine hydrobromide; Galanthamine hydrogen bromide; Jilkon hydrobromide; Lycoremine hydrobromide; Nivalin; Nivaline; Nivaline (pharmaceutical); Razadyne; Reminyl; Tamilin. CAS No. 1953-4-4. Pack Sizes: 500 mg. Product ID: NP0561. Molecular formula: C17H21NO3.HBr. Mole weight: 368.28. Custom synthesis is available. Send your inquiries for more information.
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Galanthamine
Galanthamine, also called Razadyne, found in GALANTHUS and other AMARYLLIDACEAE, a cholinesterase inhibitor prescribed to treat symptoms of mild to moderate Alzheimer's, enhances cholinergic function accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Uses: Treatment of alzheimer's disease. Group: Pharmaceutical. Alternative Names: NSC 100058; NSC100058; NSC-100058; BRN 0093736; BRN0093736; BRN-0093736; Galantamine; Reminyl; Lycoremine; (-)-Galanthamine; Galantamin; Lycoremin; Jilkon; Nivalin; Razadyne; Galantamina; Galanthaminum; Galantaminum; Razadyne ER; Galantaminum. CAS No. 357-70-0. Pack Sizes: 1 g. Product ID: B1370-343377. Molecular formula: C17H21NO3. Mole weight: 287.35. Custom synthesis is available. Send your inquiries for more information.
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Geissoschizine methyl ether
Geissoschizine methyl ether is an indole alkaloid isolated from Uncariae hooks. Geissoschizine methyl ether acts as a 5-HT7 receptor antagonist and also a potent acetylcholinesterase (AChE) inhibitor. Group: Pharmaceutical. Alternative Names: Methyl (Z)-2-[(2S,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate. CAS No. 60314-89-8. Pack Sizes: 5 mg. Product ID: NP0821. Molecular formula: C22H26N2O3. Mole weight: 366.461. Custom synthesis is available. Send your inquiries for more information.
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Ginsenoside Rg2
Ginsenoside Rg2, a steroid glycoside, is abundant in Panax ginseng root, which has been used for prevention of illness. It has a neuroprotective effect against glutamate-induced neurotoxicity through mechanisms related to anti-oxidation and anti-apoptosis. It inhibits nicotinic acetylcholine receptor-mediated Na+ influx and channel activity. It might regulate the 5-HT3A receptors that are expressed in Xenopus oocytes. It may have properties that inhibit or prevent the growth of tumors. Ginsenoside Rg2 can be used in health products. Uses: Anti-arthritic agent. Group: Pharmaceutical. Alternative Names: (3b,6a,12b)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranoside; β-D-Glucopyranoside, (3β,6α,12β)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-; Dammarane, β-D-glucopyranoside deriv.; Chikusetsusaponin I. CAS No. 52286-74-5. Pack Sizes: 100 mg. Product ID: B1370-003062. Molecular formula: C42H72O13. Mole weight: 785.01. Custom synthesis is available. Send your inquiries for more information.
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Glabredelphinine
Glabredelphinine, a naturally occurring substance, has garnered attention for its remarkable efficacy in inducing apoptosis in tumors, thus displaying its potent anti-tumor activity. Furthermore, it has exhibited potential therapeutic benefits in the treatment of Alzheimer's disease by impeding acetylcholinesterase activity. Through its multifaceted mechanisms, Glabredelphinine represents an intriguing candidate for further exploration within both oncological and neurological research domains. Group: Pharmaceutical. Alternative Names: Glabredelphinine; 132160-37-3; (3R,4S,5S,6S,8R,13R,16S,17R,18S)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadec-14-ene-4,8,9,16,18-pentol(2R,3R,4S,5S,6S,8R,13R,16S,17R,18S)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadec-14-ene-4,8,9,16,18-pentol. CAS No. 132160-37-3. Pack Sizes: 1 mg. Product ID: NP0658. Molecular formula: C22H33NO6. Mole weight: 407.507. Custom synthesis is available. Send your inquiries for more information.
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GTS-21 dihydrochloride
GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It binds to both the α4β2 and α7 subtypes, but activates only the α7 to any significant extent. Group: Pharmaceutical. Alternative Names: GTS-21; GTS 21; GTS21; DMBX-A. CAS No. 156223-05-1. Pack Sizes: 100 mg. Product ID: B0084-436419. Molecular formula: C19H20N2O2.2HCl. Mole weight: 381.3. Custom synthesis is available. Send your inquiries for more information.
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Guanosine 3',5'-cyclic monophosphate
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Group: Pharmaceutical. Alternative Names: 3:5-CGMP; D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate. CAS No. 7665-99-8. Pack Sizes: 250 mg. Product ID: B1370-013547. Molecular formula: C10H12N5O7P. Mole weight: 345.21. Custom synthesis is available. Send your inquiries for more information.
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Huperzine A
(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: N/A. CAS No. 102518-79-6. Pack Sizes: 100 mg. Product ID: NP0543. Molecular formula: C15H18N2O. Mole weight: 242.32. Custom synthesis is available. Send your inquiries for more information.
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Hyoscyamine hemisulfate
Hyoscyamine sulphate is a sulphate salt form of 3(S)-endo atropine isomer. Hyoscyamine is a non-selective antagonist of muscarinic receptors that inhbits the parasympathetic activities of acetylcholine. It is used for the treatment of stomach/intestinal problems, as well as bladder and bowel control problems, and Parkinson's disease. Uses: Adjuvants, anesthesia. Group: Pharmaceutical. Alternative Names: Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-, sulfate (2:1); 1αH,5αH-Tropan-3α-ol, (-)-tropate (ester), sulfate (2:1) (salt); Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-, sulfate (2:1) (salt; Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-, sulfate (2:1) (salt); Egazil; Hyoscyamine sulfate; Hyoscyamine sulfate (2:1); Hyoscyamine sulfate (2:1) (salt); Levsin; Levsin sulfate; Levsinex; NuLev. CAS No. 620-61-1. Pack Sizes: 1mg;1g;10g. Product ID: NP0030. Molecular formula: C17H23NO3.1/2H2O4S. Mole weight: 676.82. Custom synthesis is available. Send your inquiries for more information.
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Ipidacrine hydrochloride hydrate
Ipidacrine is a drug used for the treatment of memory disorders. It acts as a reversible acetylcholinesterase inhibitor. Group: Pharmaceutical. Alternative Names: Senita; 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride hydrate. CAS No. 118499-70-0. Pack Sizes: 1 g. Product ID: B0046-013871. Molecular formula: C12H16N2.HCl.H2O. Mole weight: 242.75. Custom synthesis is available. Send your inquiries for more information.
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Meobal-[d3]
Meobal-[d3] is a deuterium labelled Meobal, an acetylcholinesterase inhibitor used as an insecticide. Group: Pharmaceutical. Alternative Names: Meobal-d3. Pack Sizes: 10 mg. Product ID: BLP-014105. Molecular formula: C10H10D3NO2. Mole weight: 182.23. Custom synthesis is available. Send your inquiries for more information.
Nitenpyram, a natural product found in Streptomyces canus, is a nicotinic acetylcholine receptor (AchR) agonist used in veterinary medicine to treat parasites of livestock and pets. Uses: The treatment of parasites. Group: Pharmaceutical. Alternative Names: (E)-Nitenpyram; Capstar; TI 304; TI304; TI-304; (1E)-N-[(6-Chloro-3-pyridinyl)methyl]-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine; (E)-N-(6-Chloro-3-pyridylmethyl)-N-ethyl-N'-methyl-2-nitroethylene-1,1-diamine; Bestguard; Niterndipoine. CAS No. 150824-47-8. Pack Sizes: 10 g. Product ID: BBF-05823. Molecular formula: C11H15ClN4O2. Mole weight: 270.72. Custom synthesis is available. Send your inquiries for more information.
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N-Nitrosocytisine
N-Nitrosocytisine is a derivative of Cytisine, which is a nicotinic acetylcholine receptor (nAChR) agonist. Group: Pharmaceutical. Alternative Names: (1R,5R)-1,2,3,4,5,6-Hexahydro-3-nitroso-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one; 12-Nitrosocytisine; Nitrosocytisine; 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-nitroso-, (1R,5R)-. CAS No. 19634-60-7. Pack Sizes: 100 mg. Product ID: B1370-343453. Molecular formula: C11H13N3O2. Mole weight: 219.24. Custom synthesis is available. Send your inquiries for more information.
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Norhyoscyamine sulfate
Norhyoscyamine sulfate, a potent anticholinergic agent, exerts its therapeutic effects through the inhibition of acetylcholine activity, which makes it a valuable treatment option for several types of gastrointestinal disorders, such as motility disorders, as well as urinary incontinence. Moreover, this multifaceted medication exhibits remarkable preoperative benefits, as it can effectively reduce both respiratory and digestive secretions, underscoring its versatility and potential for widespread clinical use. Group: Pharmaceutical. Alternative Names: Norhyoscyamine. CAS No. 537-29-1. Pack Sizes: 100 mg. Product ID: B1370-152647. Molecular formula: C16H21NO3. Mole weight: 275.34. Custom synthesis is available. Send your inquiries for more information.
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Phencarol
Phencarol is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists. Group: Pharmaceutical. Alternative Names: Quifenadine [INN]; 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol; 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol; Fenkarol. CAS No. 10447-39-9. Pack Sizes: 1mg;1g;10g. Product ID: 10447-39-9. Molecular formula: C20H23NO. Mole weight: 293.41. Custom synthesis is available. Send your inquiries for more information.
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Physostigmine salicylate
Physostigmine salicylate is a cholinesterase inhibitor that can cross blood-brain barrier. It forms slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). It has been used to improve cognitive ability and treat glaucoma. Group: Pharmaceutical. Alternative Names: [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate (2-hydroxybenzoic acid) salt. CAS No. 57-64-7. Pack Sizes: 250 mg. Product ID: B0084-028331. Molecular formula: C22H27N3O5. Mole weight: 413.5. Custom synthesis is available. Send your inquiries for more information.
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Propoxur
Propoxur is a carbamate insecticide and an acetylcholinesterase inhibitor. Group: Pharmaceutical. Alternative Names: Baygon; 2-Isopropoxyphenyl methylcarbamate; Aprocarb; Sendran; Blattanex; Mrowkozol; 2-Isopropoxyphenyl N-methylcarbamate; 2-(1-Methylethoxy)phenol methylcarbamate. CAS No. 114-26-1. Pack Sizes: 1mg;1g;10g. Product ID: 114-26-1. Molecular formula: C11H15NO3. Mole weight: 209.24. Custom synthesis is available. Send your inquiries for more information.
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(R)-Coclaurine
(R)-Coclaurine is a nicotinic acetylcholine receptor antagonist isolated from a variety of plant sources. Group: Pharmaceutical. Alternative Names: 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1R)-. CAS No. 2196-60-3. Pack Sizes: 5 mg. Product ID: B2703-279867. Molecular formula: C17H19NO3. Mole weight: 285.34. Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine EP Impurity B
An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. Alternative Names: (R,S)-3-[1-(Dimethylamino)ethyl]phenyl dimethylcarbamate; RivastigMine USP RC B; Desmethyl Rivastigmine; N-Desethyl N-Methyl rac-Rivastigmine; N,N-Dimethylcarbamic acid 3-[(RS)-1-(dimethyl amino) ethyl]phenyl ester. CAS No. 25081-93-0. Pack Sizes: 10 mg. Product ID: B1370-264654. Molecular formula: C13H20N2O2. Mole weight: 236.32. Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine Impurity F
An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. Alternative Names: (αS)-3-Methoxy-N,N,α-trimethylbenzenemethanamine; (S)-1-(3-Methoxyphenyl)-N,N-dimethylethanamine; Rivastigmine EP Impurity F. CAS No. 889443-69-0. Pack Sizes: 25 mg. Product ID: B2694-479199. Molecular formula: C11H17NO. Mole weight: 179.26. Custom synthesis is available. Send your inquiries for more information.
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Rivastigmine USP Related Compound F
An impurity of Rivastigmine, a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. Alternative Names: 3-Vinylphenyl ethyl(methyl)carbamate; 3-Ethenylphenyl ethyl(methyl)carbamate; N-Ethyl-N-methyl-3-vinylphenyl Carbamate. CAS No. 1346602-84-3. Pack Sizes: 5 g. Product ID: B2694-479202. Molecular formula: C12H15NO2. Mole weight: 205.26. Custom synthesis is available. Send your inquiries for more information.
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Sevoflurane
Sevoflurane is an ether inhalation anaesthetic agent primarily used for the induction and maintenance of general anesthesia. It has been shown to enhance inhibitory postsynaptic channel activity (GABA and glycine), and inhibit excitatory synaptic channel activity (NMDA, nicotinic acetylcholine, serotonin, and glutamate) in the central nervous system. Group: Pharmaceutical. Alternative Names: Sevofluran; Ultane; 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane; Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl ester; Fluoromethyl 1,1,1,3,3,3-Hexafluoro-2-propyl ester. CAS No. 28523-86-6. Pack Sizes: 1mg;1g;10g. Product ID: 28523-86-6. Molecular formula: C4H3F7O. Mole weight: 200.1. Custom synthesis is available. Send your inquiries for more information.
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(±)-Vesamicol hydrochloride
(±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (Ki = 2 nM) that blocks the loading of acetylcholine into synaptic vesicles of cholinergic nerve terminals. The inhibition by Vesamicol attenuates acetylcholine neuronal signaling without direct effecys on signaling mechanisms. Group: Pharmaceutical. Alternative Names: AH5183 hydrochloride; AH 5183 hydrochloride; (±)-trans-2-(4-Phenylpiperidinyl)cyclohexanol hydrochloride; 2-(4-Phenylpiperidino)cyclohexanol hydrochloride; Cyclohexanol, 2-(4-phenylpiperidino)-, hydrochloride. CAS No. 120447-62-3. Pack Sizes: 100 mg. Product ID: B1370-072516. Molecular formula: C17H25NO.HCl. Mole weight: 295.85. Custom synthesis is available. Send your inquiries for more information.
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VU0152099
VU0152099 is a potent and selective allosteric potentiator of M4 mAChR with an EC50 of 380 ± 93 nM. VU0152099 has no agonist activity but potentiated responses of M4 to acetylcholine. Group: Pharmaceutical. Alternative Names: VU 0152099; VU-0152099. CAS No. 612514-42-8. Pack Sizes: 25 mg. Product ID: B1370-382526. Molecular formula: C18H17N3O3S. Mole weight: 355.41. Custom synthesis is available. Send your inquiries for more information.
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VU0467154
VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor. It potentiates acetylcholine responses in CHO cells expressing M4 receptors (EC50s = 17.7, 630, and 1,000 nM for rat, human, and cynomolgus monkey receptors, respectively). Group: Pharmaceutical. Alternative Names: 5-Amino-3,4-dimethyl-N-[[4-(trifluoromethylsulfonyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide. CAS No. 1451993-15-9. Pack Sizes: 100 mg. Product ID: B2693-292401. Molecular formula: C17H15F3N4O3S2. Mole weight: 444.45. Custom synthesis is available. Send your inquiries for more information.
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XMC-[d3]
XMC-[d3] is a deuterium labelled 3,5-Xylyl methylcarbamate, an acetylcholinesterase inhibitor used as an insecticide. Group: Pharmaceutical. Alternative Names: XMC-d3; 3,5-Xylyl methylcarbamate-d3; Cosban-d3; Maqbarl-d3; Macbal-d3. Pack Sizes: 10 mg. Product ID: BLP-014106. Molecular formula: C10H10D3NO2. Mole weight: 182.23. Custom synthesis is available. Send your inquiries for more information.
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