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| Product | Description | |
|---|---|---|
| A-9758 | A-9758 is an RORγ ligand and a potent and selective RORγt inverse agonist (IC50 = 5 nM), and shows strong potency against IL-17A release. A-9758 can effectively inhibit Th17 differentiation and Th17 effector function. A-9758 significantly attenuates IL-23 driven psoriasiform dermatitis and effectively blocks skin and joint inflammation. Group: Pharmaceutical. Alternative Names: 4-Piperidinecarboxylic acid, 1-[2,4-dichloro-3-[[1,4-dimethyl-6-(trifluoromethyl)-1H-indol-2-yl]methyl]benzoyl]-; 1-(2,4-Dichloro-3-{[1,4-dimethyl-6-(trifluoromethyl)-1H-indol-2-yl]methyl}benzoyl)-4-piperidinecarboxylic acid. CAS No. 2055271-22-0. Pack Sizes: 1mg;1g;10g. Product ID: 2055271-22-0. Molecular formula: C25H23Cl2F3N2O3. Mole weight: 527.36. Custom synthesis is available. Send your inquiries for more information. |  London |
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