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| Product | Description | |
|---|---|---|
| 5-Hydroxymethyl-2'-deoxyuridine | 5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 5-Hydroxymethyl-2'-deoxyuridine;5116-24-5;alpha-Hydroxythymidine;5-Hydroxymethyldeoxyuridine;2'-Deoxy-5-(hydroxymethyl)uridine;HMdU;5-HMdU;alpha-Hydroxy-thymidin;Thymidine, alpha-hydroxy-;CHEBI:61288;Uridine, 2'-deoxy-5-(hydroxymethyl)-;2'-Deoxy-5-hydroxymethyluridine;5-Hydroxymethyl-deoxyuridine;EJZ33W33JN;1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-. CAS No. 5116-24-5. Pack Sizes: 1 g. Product ID: B1370-120698. Molecular formula: C14H11N5O2S. Mole weight: 313.34. Custom synthesis is available. Send your inquiries for more information. |  London |
| 5-Hydroxymethyl-2'-deoxyuridine 5'-monophosphate Sodium | 5-Hydroxymethyl-2'-deoxyuridine 5'-monophosphate Sodium is a nucleotide that can be used in DNA bioresearch and repair, as well as cancer treatment. It inhibits the synthesis of DNA by binding to the enzyme DNMT1 and causing it to lose its ability to produce DNA. It also suppresses RNA synthesis to induce cell death. Group: Pharmaceutical. Alternative Names: 5-Hydroxymethyl-2'-deoxyuridine 5'-monophosphate monosodium; 5-hydroxymethyl-dUMP sodium. CAS No. 160509-68-2. Pack Sizes: 10 mg. Product ID: B2693-076438. Molecular formula: C10H14N2NaO9P. Mole weight: 360.19. Custom synthesis is available. Send your inquiries for more information. | London |
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