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| Product | Description | |
|---|---|---|
| 3'-O-Methylguanosine | 3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. Group: Pharmaceutical. Alternative Names: 3'-(O-Methyl) Guanosine; 3'-O-Methyl-D-guanosine; 3'-O-Methyl guanosine; O3'-methyl-guanosine; 3'-OMe-G; 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one. CAS No. 10300-27-3. Pack Sizes: 50 mg. Product ID: B2706-306475. Molecular formula: C11H15N5O5. Mole weight: 297.27. Custom synthesis is available. Send your inquiries for more information. |  London |
| 7-Methyl-3'-O-methylguanosine 5'-(trihydrogen diphosphate), inner salt, TEA salt | 7-Methyl-3'-O-methylguanosine 5'-(trihydrogen diphosphate), inner salt, TEA salt is a modified nucleoside used in research. It consists of guanosine with methyl groups at the 7th position of the base and the 3' carbon of the ribose sugar. It has a diphosphate group at the 5' carbon of the ribose with three hydrogen atoms bound to the phosphates. It is commonly employed in biochemical studies, especially in RNA research. Group: Pharmaceutical. Alternative Names: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-3'-O-methyl-, inner salt, compd. with N,N-diethylethanamine (1:x); Triethylamine ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-3,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl diphosphate (1:x); 3'-OMe-m7GDP TEA Salt; Guanosine 5'-(trihydrogen diphosphate), 7-Methyl-3'-O-Methyl-, inner Salt, compd. with N,N-diethylethanamine. CAS No. 2089461-52-7. Pack Sizes: 100 mg. Product ID: B1370-088411. Molecular formula: C12H19N5O11P2.xC6H15N. Mole weight: 471.26 (free base). Custom synthesis is available. Send your inquiries for more information. | London |
| N2-iso-Butyroyl-3'-O-methylguanosine | N2-iso-Butyroyl-3'-O-methylguanosine - a valuable tool for biomedicine exploration. This organic compound finds frequent utility in mRNA synthesis, the development of capping analogs and high-affinity RNA aptamers. Its worth extends beyond these applications, with capabilities to examine structural and functional elements of mRNA capping enzymes. Group: Pharmaceutical. Alternative Names: Guanosine, 3'-O-methyl-N-(2-methyl-1-oxopropyl)-; N-(9-((2R,3R,4S,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)isobutyramide. CAS No. 160107-07-3. Pack Sizes: 1 g. Product ID: B2706-346657. Molecular formula: C15H21N5O6. Mole weight: 367.36. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside | 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a remarkable biomedical entity, diligently confronting the pernicious wrath of herpes simplex virus and varicella-zoster virus, rendering them futile through the inhibition of viral DNA synthesis and replication. Group: Pharmaceutical. Alternative Names: 6-Chloro-2'-O-methylguanosine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-Amino-6-chloro-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(2-O-methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2'-O-Methyl-2-amino-6-chloropurine riboside. CAS No. 194034-59-8. Pack Sizes: 25 mg. Product ID: B2706-047011. Molecular formula: C11H14ClN5O4. Mole weight: 315.71. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-OMe-dmf-G-CE Phosphoramidite | 2'-OMe-dmf-G-CE Phosphoramidite, a vital compound in the biomedicine industry, is leveraged for the crucial synthesis of oligonucleotides. These tiny yet potent molecules are widely utilized in treating an array of afflictions such as cancer, viral infections, and genetic disorders. Devised to heighten the steadfastness and efficacy of oligonucleotides, our product offers patients the potential for better therapeutic outcomes. Group: Pharmaceutical. Alternative Names: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methylguanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; DMT-2'-O-Me-G(dmf)-CE Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-OMe-G-CE Phosphoramidite; 2'-O-Methyl Guanosine (n,n-dmf) CED phosphoramidite. CAS No. 128219-77-2. Pack Sizes: 1 g. Product ID: B2706-004449. Molecular formula: C44H55N8O8P. Mole weight: 854.92. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-OMe-G(iBu)-3'-phosphoramidite | 2'-OMe-G(iBu)-3'-phosphoramidite is a modified phosphoramidite designed for the synthesis of stable and efficient RNA oligonucleotides. The protective groups and modifications, such as 5'-O-DMTr, N2-isobutyryl, and 2'-O-methyl, enhance the stability of the resulting nucleic acids and facilitate their incorporation into nucleic acid chains during solid-phase synthesis. This compound is crucial in producing antisense oligonucleotides, siRNA, probes, and primers, providing enhanced resistance to enzymatic degradation and improved performance in various applications. Group: Pharmaceutical. Alternative Names: 5'-O-DMTr-N2-iBu-2'-O-Me-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyroyl-2'-O-methylguanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite; 2'-OMe-iBu-G CE phosphoramidite; 5'-O-DMT-2'-O-Me-G(iBu) phosporamidite; DMT-2'-O-Me-rG(iBu) amidite; N2-Isobutyryl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-Guanosine-3'-CE-Phosphoramidite. CAS No. 150780-67-9. Pack Sizes: 5 g. Product ID: B2706-084599. Molecular formula: C45H56N7O9P. Mole weight: 869.94. Custom synthesis is available. Send your inquiries for more information. | London |
| N2-DMF-2'-O-methylguanosine | N2-DMF-2'-O-methylguanosine, an indispensable biomedical resource, showcases remarkable efficacy in combating targeted illnesses. Its distinctive composition as a modified nucleoside endows it with unparalleled potential in countering RNA viruses. Addressing the pressing need for effective antiviral treatments, especially for respiratory syncytial virus (RSV) and influenza, this compound serves as a pivotal asset in formulating groundbreaking therapies. Group: Pharmaceutical. Alternative Names: DMF-2'-OMe-G; N2-[(dimethylamino)methylidene]-2'-O-methyl-D-guanosine; N2-DMF-2'-O-methyl-D-guanosine; N2-DMF-2'-OMe-rG; Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl-; N-(Dimethylaminomethylene)-2'-O-methylguanosine. CAS No. 183737-04-4. Pack Sizes: 1 g. Product ID: B1370-339986. Molecular formula: C14H20N6O5. Mole weight: 352.35. Custom synthesis is available. Send your inquiries for more information. | London |
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