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2-Thiouridine, an esteemed biomedical marvel, is renowned for its profound efficacy in combatting malignant neoplasms and thwarting viral affections. This exalted nucleoside derivative ingeniously integrates itself into RNA, instigating the impeding of viral propagation and invoking apoptosis within neoplastic entities. Its exceptional anti-tumorigenic and antiviral prowess has propelled 2-Thiouridine to the vanguard of biomedical exploration and therapeutic breakthroughs. Group: Pharmaceutical. Alternative Names: 1-β-D-Ribofuranosyl-2-thiouracil; 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; Thiouridine. CAS No. 20235-78-3. Pack Sizes: 1 g. Product ID: B1370-331350. Molecular formula: C9H12N2O5S. Mole weight: 260.27. Custom synthesis is available. Send your inquiries for more information.
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5-Methoxycarbonylmethyl-2-thiouridine
5-(Methoxycarbonylmethyl)-2-thiouridine can be used as analyte in biological study for attomole quantification and global profile of RNA modifications in study of epitranscriptome of human neural stem cells. It can also be used to biological computational studies to provide insights into effects of modified ribonucleotides and Mg2+ on structures and stabilities of tRNAs. A trace nucleoside, isolated from yeast transfer RNA. A nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria. Group: Pharmaceutical. Alternative Names: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-, methyl ester; 5-(Methoxycarbonylmethyl)-2-thiouridine; 5-(2-methoxy-2-oxoethyl)-1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-(2-methoxy-2-oxoethyl)2-thiouridine. CAS No. 20299-15-4. Pack Sizes: 25 mg. Product ID: B1370-292000. Molecular formula: C12H16N2O7S. Mole weight: 332.33. Custom synthesis is available. Send your inquiries for more information.
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5-methylaminomethyl-2-thiouridine
5-methylaminomethyl-2-thiouridine, an indispensable compound in biomedicine, serves as a linchpin for scientific advancements. With widespread application in the exploration of antiviral agents and remedies for diverse ailments, this compound assumes a pivotal function. By enhancing the effectiveness of therapeutic interventions against viral infections, it unravels intricate mechanisms underlying drug action. Group: Pharmaceutical. Alternative Names: 5-(Methylaminomethyl)-2-thiouridine; 2-Thio-5-(N-methylaminomethyl)uridine; 5-N-Methylaminomethyl-2-thiouridine; 2-Thio-5-methylaminomethyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-((methylamino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-[(Methylamino)methyl]-1-(β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone. CAS No. 32860-54-1. Pack Sizes: 1 mg. Product ID: B2706-340121. Molecular formula: C11H17N3O5S. Mole weight: 303.34. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite is a phosphoramidite derivative used for the solid-phase research and development of modified RNA sequences. With its 5'-O-DMT protection, 2'-O-TBDMS modification and 2-thiouridine incorporation, it enables the controlled research and development of RNA molecules for studying RNA-protein interactions and RNA-based therapeutics targeting diseases like cancer and viral infections. Group: Pharmaceutical. Alternative Names: 2'-OTBS 2-Thio-U amidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 163496-21-7. Pack Sizes: 1 g. Product ID: B1370-313029. Molecular formula: C45H61N4O8PSSi. Mole weight: 877.11. Custom synthesis is available. Send your inquiries for more information.
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2-Thio-UTP tetrasodium salt
2-ThioUTP tetrasodium salt is a potent and selective P2Y2 agonist (EC50 = 0.035, 0.35 and 1.5 μM for hP2Y2, hP2Y4 and hP2Y6 receptors, respectively). Group: Pharmaceutical. Alternative Names: 2-Thiouridine 5'-triphosphate tetrasodium salt; 2-Thiouridine 5'-(tetrahydrogen triphosphate) tetrasodium salt; ((2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate tetrasodium salt; Uridine 5'-(tetrahydrogen triphosphate), 2-thio-, sodium salt (1:4). CAS No. 1343364-70-4. Pack Sizes: 1 mg. Product ID: B1370-170390. Molecular formula: C9H11N2Na4O14P3S. Mole weight: 588.13. Custom synthesis is available. Send your inquiries for more information.
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