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| Product | Description | |
|---|---|---|
| 2,4-Thiazolidinedione | 2,4-Thiazolidinedione. CAS No. 2295-31-0. |  CARBONE SCIENTIFIC UK |
| 5-{4-[2-(5-Ethyl-2-Pyridinyl) Ethoxyl] Benzyldene} -2,4-thiazolidinedione | 5-{4-[2-(5-Ethyl-2-Pyridinyl) Ethoxyl] Benzyldene} -2,4-thiazolidinedione Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 144809-28-9. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals. |  UK / EU / USA / Japan |
| 5-(4-Chlorobenzylidene)-2,4-thiazolidinedione | 5-(4-Chlorobenzylidene)-2,4-thiazolidinedione, a well-researched organic compound, exhibits remarkable promise in treating diabetes mellitus type 2 owing to its ability to function as an agonist for peroxisome proliferator-activated receptor gamma (PPAR-γ). PPAR-γ is implicated in the modulation of glucose and lipid metabolism. Beyond its anti-diabetic attributes, this compound has been the subject of inquiry for its potential anti-cancer properties. The chemical's therapeutic significance is evidenced by the numerous investigations conducted on its biological activity. Group: Pharmaceutical. Alternative Names: 5-(4-Chloro-benzylidene)-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[(4-chlorophenyl)methylene]-. CAS No. 24138-83-8. Pack Sizes: 50 mg. Product ID: B0001-284763. Molecular formula: C10H6ClNO2S. Mole weight: 239.673. Custom synthesis is available. Send your inquiries for more information. |  London |
| 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, a chemical compound with potential therapeutic applications in diabetes and related metabolic disorders, exhibits insulin sensitizing properties that are aimed at lowering high-blood glucose levels and enhancing insulin sensitivity. Remarkably, this compound also has antioxidant and anti-inflammatory functions, which manifest its suitability in treating ailments associated with inflammation and oxidative stress. Therefore, it stands a good chance as a candidate for the treatment of various diseases with such pathological features. Group: Pharmaceutical. Alternative Names: 2,4-Thiazolidinedione, 5-[(2-hydroxyphenyl)methylene]-. CAS No. 6325-94-6. Pack Sizes: 50 mg. Product ID: B0001-284762. Molecular formula: C10H7NO3S. Mole weight: 221.23. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione | 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione is an impurity of Pioglitazone, a PPAR agonist that has antidiabetic activity in patients with type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-; 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione; 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene]-1,3-thiazolidine-2,4-dione; 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzylidene]thiazolidine-2,4-dione. CAS No. 144809-28-9. Pack Sizes: 100 mg. Product ID: NP3434. Molecular formula: C19H18N2O3S. Mole weight: 354.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Hydroxy Pioglitazone-[d4] (M-IV) | Hydroxy Pioglitazone-[d4] (M-IV) is the labelled analogue of Hydroxy Pioglitazone (M-IV), which is a metabolite of Pioglitazone, a PPARγ agonist used as an anti-diabetic drug. Group: Pharmaceutical. Alternative Names: Hydroxy Pioglitazone-d4 (M-IV); 5-[[4-[2-[5-(1-Hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione-d4. CAS No. 1188263-49-1. Pack Sizes: 1 mg. Product ID: BLP-008210. Molecular formula: C19H16D4N2O4S. Mole weight: 376.46. Custom synthesis is available. Send your inquiries for more information. | London |
| iCRT 14 | iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling. It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Group: Pharmaceutical. Alternative Names: iCRT14; iCRT-14; iCRT 14; Wnt inhibitor; CHEMBL3589010; STK155594; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione. CAS No. 677331-12-3. Pack Sizes: 25 mg. Product ID: B0084-272145. Molecular formula: C21H17N3O2S. Mole weight: 375.44. Custom synthesis is available. Send your inquiries for more information. | London |
| MSDC-0160 | MSDC-0160 reduces resistance in the insulin/IGF-1 signaling pathway and restores IGF-1-induced Akt and GSK-3 phosphorylation. Group: Pharmaceutical. Alternative Names: Mitoglitazone; CAY10415; 5-[[4-[2-(5-Ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione; Pioglitazone Ketone; 5-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione; 5-{4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione. CAS No. 146062-49-9. Pack Sizes: 25 mg. Product ID: B0084-311834. Molecular formula: C19H18N2O4S. Mole weight: 370.42. Custom synthesis is available. Send your inquiries for more information. | London |
| MSDC-0602 | MSDC-0602 is an insulin sensitizer that has the potential to treat diabetes and other inflammatory diseases. It exhibits low affinity for binding and activation of PPARγ. Group: Pharmaceutical. Alternative Names: MSDC-0602; MSDC0602; MSDC 0602; 5-{4-[2-(3-Methoxyphenyl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]methyl]-. CAS No. 1133819-87-0. Pack Sizes: 50 mg. Product ID: B0084-284775. Molecular formula: C19H17NO5S. Mole weight: 371.407. Custom synthesis is available. Send your inquiries for more information. | London |
| Pioglitazone EP Impurity A | Pioglitazone EP Impurity A is an impurity of Pioglitazone, a PPAR agonist that has antidiabetic activity in patients with type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: (5RS)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]-phenyl]methyl]-5-hydroxythiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-5-hydroxy-; Pioglitazone Impurity A; 5-Hydroxy Pioglitazone Impurity; Pioglitazone 5-Hydroxy Metabolite; 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-5-hydroxy-2,4-thiazolidinedione; 5-Hydroxy pioglitazone; Pioglitazone hydrochloride impurity A [EP]; Hydroxypioglitazone; 5-Hydroxypioglitazone; (±)-5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl}-5-hydroxythiazolidine-2,4-dione. CAS No. 625853-74-9. Pack Sizes: 10 mg. Product ID: B2694-262097. Molecular formula: C19H20N2O4S. Mole weight: 372.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Pioglitazone hydrochloride | Pioglitazone hydrochloride, a thiazolidinedione antidiabetic drug, is a cytochrome P450 (CYP)2C8 and CYP3A4 enzymes inhibitor with Kis of 1.7, 11.8 and 32.1 μM for CYP2C8, CYP3A4 and CYP2C9, respectively. It is an agonist of the peroxisome proliferator-activated receptor γ. Uses: Hypoglycemic agents. Group: Pharmaceutical. Alternative Names: 5-[[4-[2-(5-Ethyl-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione Hydrochloride; AD-4833; Actos; U-72107A; 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride; NSC 758876; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, monohydrochloride. CAS No. 112529-15-4. Pack Sizes: 250 mg. Product ID: BBF-05868. Molecular formula: C19H20N2O3S.HCl. Mole weight: 392.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Protein Kinase Inhibitors 1 | Protein Kinase Inhibitors 1 is a HIPK2 inhibitor with IC50 of 74 nM and Kd of 9.5 nM. Group: Pharmaceutical. Alternative Names: 2,4-Thiazolidinedione, 5-[[1,2-dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-; 5-((2-oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl)methylene)thiazolidine-2,4-dione; 5-[[1,2-Dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-2,4-thiazolidinedione. CAS No. 1365986-44-2. Pack Sizes: 20 mg. Product ID: B0084-284772. Molecular formula: C18H17N5O3S. Mole weight: 383.43. Custom synthesis is available. Send your inquiries for more information. | London |
| Troglitazone-[d4] | One of the isotopic labelled form of Troglitazone, which could be used for the treatment of diabetes and inflammation. Group: Pharmaceutical. Alternative Names: 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione-d4. Pack Sizes: 5 mg. Product ID: BLP-014126. Molecular formula: C24H23NO5SD4. Mole weight: 445.57. Custom synthesis is available. Send your inquiries for more information. | London |
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